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Importance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin

  1. TitleImportance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin
    Author Swietach P.
    Co-authors Hulíková Alžbeta 1979    ORCID

    Patiar Shalini

    Vaughan-Jones R.D.

    Harris A.L.

    Source document PLoS ONE. Vol. 7, no. 4 (2012), p. e.35949
    Languageeng - English
    Document kindrozpis článkov z periodík (rbx)
    CitationsMadsen, J (Madsen, Jeppe)[ 1,2 ] ; Canton, I (Canton, Irene)[ 1 ] ; Warren, NJ (Warren, Nicholas J.)[ 2 ] ; Themistou, E (Themistou, Efrosyni)[ 2 ] ; Blanazs, A (Blanazs, Adam)[ 2 ] ; Ustbas, B (Ustbas, Burcin)[ 1 ] ; Tian, XH (Tian, Xiaohe)[ 1 ] ; Pearson, R (Pearson, Russell)[ 1 ] ; Battaglia, G (Battaglia, Giuseppe)[ 1 ] ; Lewis, AL (Lewis, Andrew L.)[ 3 ] ; Armes, SP Nile Blue-Based Nanosized pH Sensors for Simultaneous Far-Red and Near-Infrared Live Bioimaging JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 135 Issue: 39 Pages: 14863-14870 , 2013
    Parks, Scott K.; Chiche, Johanna; Pouyssegur, Jacques Disrupting proton dynamics and energy metabolism for cancer therapy NATURE REVIEWS CANCER Volume: 13 Issue: 9 Pages: 611-623 Published: SEP 2013
    Dicheva, BM (Dicheva, Bilyana M.)[ 1 ] ; ten Hagen, TLM (ten Hagen, Timo L. M.)[ 1 ] ; Schipper, D (Schipper, Debby)[ 1 ] ; Seynhaeve, ALB (Seynhaeve, Ann L. B.)[ 1 ] ; van Rhoon, GC (van Rhoon, Gerard C.)[ 2 ] ; Eggermont, AMM (Eggermont, Alexander M. M.)[ 1,3 ] ; Koning, GA Targeted and heat-triggered doxorubicin delivery to tumors by dual targeted cationic thermosensitive liposomes JOURNAL OF CONTROLLED RELEASE Volume: 195 Pages: 37-48, 2014
    Salerno, M (Salerno, Manuela)[ 1,2 ] ; Avnet, S (Avnet, Sofia)[ 1 ] ; Bonuccelli, G (Bonuccelli, Gloria)[ 1,2 ] ; Hosogi, S (Hosogi, Shigekuni)[ 1,3 ] ; Granchi, D (Granchi, Donatella)[ 1 ] ; Baldini, N Impairment of Lysosomal Activity as a Therapeutic Modality Targeting Cancer Stem Cells of Embryonal Rhabdomyosarcoma Cell Line RD PLOS ONE Volume: 9 Issue: 10 , 2014
    Madhusudhan, A (Madhusudhan, Alle)[ 1 ] ; Reddy, GB (Reddy, Gangapuram Bhagavanth)[ 1 ] ; Venkatesham, M (Venkatesham, Maragoni)[ 1 ] ; Veerabhadram, G (Veerabhadram, Guttena)[ 1 ] ; Kumar, DA (Kumar, Dudde Anil)[ 3 ] ; Natarajan, S (Natarajan, Sumathi)[ 3 ] ; Yang, MY (Yang, Ming-Yeh)[ 2 ] ; Hu, AR (Hu, Anren)[ 2 ] ; Singh, SS Efficient pH Dependent Drug Delivery to Target Cancer Cells by Gold Nanoparticles Capped with Carboxymethyl Chitosan INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 15 Issue: 5 Pages: 8216-8234, 2014
    Edmondson, R (Edmondson, Rasheena); Broglie, JJ (Broglie, Jessica Jenkins); Adcock, AF (Adcock, Audrey F.); Yang, LJ Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES Volume: 12 Issue: 4 Pages: 207-218, 2014
    Man, CH (Man, Cheuk Him)[ 1 ] ; Lam, SSY (Lam, Stephen S. Y.)[ 1 ] ; Sun, MKH (Sun, Murphy K. H.)[ 1 ] ; Chow, HCH (Chow, Howard C. H.)[ 1 ] ; Gill, H (Gill, Harinder)[ 1 ] ; Kwong, YL (Kwong, Yok Lam)[ 1 ] ; Leung, AYH A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML BLOOD Volume: 123 Issue: 16 Pages: 2530-2539, 2014
    Taylor, S (Taylor, Sophie)[ 1 ] ; Spugnini, EP (Spugnini, Enrico Pierluigi)[ 2 ] ; Assaraf, YG (Assaraf, Yehuda G.)[ 4 ] ; Azzarito, T (Azzarito, Tommaso)[ 3 ] ; Rauch, C (Rauch, Cyril)[ 1 ] ; Fais, S Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach DRUG RESISTANCE UPDATES Volume: 23 Pages: 69-78 , 2015
    Brosseau, N. ; Andreev, E. ; Ramotar, D. Complementation of the Yeast Model System Reveals that Caenorhabditis elegans OCT-1 Is a Functional Transporter of Anthracyclines PLOS ONE, vol. 10, iss. 7, 2015, artic. nu e0133182.
    CategoryADCA - Scientific papers in foreign journals registered in Current Contents Connect with IF (impacted)
    Category of document (from 2022)V3 - Vedecký výstup publikačnej činnosti z časopisu
    Type of documentčlánok
    Year2012
    Registered inWOS
    Registered inSCOPUS
    DOI 10.1371/journal.pone.0035949
    article

    article

    rokCCIFIF Q (best)JCR Av Jour IF PercSJRSJR Q (best)CiteScore
    A
    rok vydaniarok metrikyIFIF Q (best)SJRSJR Q (best)
    201220114.092Q12.425Q1
Number of the records: 1  

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