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Therapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans

  1. TitleTherapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans
    Author Weisová Petronela
    Co-authors Cehlár Ondrej    ORCID

    Škrabana Rostislav    ORCID

    Žilková Monika    ORCID

    Filipčík Peter    ORCID

    Kováčech Branislav    SCOPUS

    Smolek K.

    Smolek Tomáš    SCOPUS

    Kontseková Eva    SCOPUS

    Žilka Norbert    SCOPUS

    Novák Michal    SCOPUS

    Co-authors Prčina Michal Wojčiaková Ľubica Fialová Ľubica
    Source document Acta Neuropathologica Communications. Vol. 7, no. 1 (2019), art. no. 129
    Languageeng - English
    Document kindrozpis článkov z periodík (rbx)
    CitationsFERNANDEZ-VEGA, I. - LORENTE-GEA, L. - MARTIN, C. - QUIROS, L.M. Heparan sulfate proteoglycans as possible diagnostic molecular tools with therapeutic potential in Alzheimer ' s disease. ISSN 1673-5374.
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    CHANDUPATLA, R.R. - FLATLEY, A. - FEEDERLE, R. - MANDELKOW, E.M. - KANIYAPPAN, S. Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes. In ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS. 2020, vol. 6, no. 1. Dostupné na: https://doi.org/10.1002/trc2.12097.
    HORIE, K. - BARTHELEMY, N.R. - SATO, C. - BATEMAN, R.J. CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease. In BRAIN. ISSN 0006-8950, FEB 2021, vol. 144, 2, p. 515-527. Dostupné na: https://doi.org/10.1093/brain/awaa373.
    ZHAO, J.F. - WU, H.R. - TANG, X.Q. Tau internalization: A complex step in tau propagation. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, MAY 2021, vol. 67. Dostupné na: https://doi.org/10.1016/j.arr.2021.101272.
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    WU, M.X. - ZHANG, M.Q. - YIN, X.P. - CHEN, K. - HU, Z.J. - ZHOU, Q. - CAO, X.M. - CHEN, Z.Y. - LIU, D. The role of pathological tau in synaptic dysfunction in Alzheimer's diseases. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, NOV 10 2021, vol. 10, no. 1. Dostupné na: https://doi.org/10.1186/s40035-021-00270-1.
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    MORETTO, E. - STUART, S. - SURANA, S. - VARGAS, J.N.S. - SCHIAVO, G. The Role of Extracellular Matrix Components in the Spreading of Pathological Protein Aggregates. In FRONTIERS IN CELLULAR NEUROSCIENCE. APR 29 2022, vol. 16. Dostupné na: https://doi.org/10.3389/fncel.2022.844211.
    WASIELEWSKA, J.M. - CHAVES, J.C.S. - JOHNSTON, R.L. - MILTON, L.A. - HERNáNDEZ, D. - CHEN, L.Y. - SONG, J. - LEE, W. - LEINENGA, G. - NISBET, R.M. - PéBAY, A. - GöTZ, J. - WHITE, A.R. - OIKARI, L.E. A sporadic Alzheimer's blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies. In THERANOSTICS. ISSN 1838-7640, 2022, vol. 12, no. 16, p. 6826-6847. Dostupné na: https://doi.org/10.7150/thno.72685.
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    CategoryADMA - Scientific papers in foreign impacted journals registered in Web of Sciences or Scopus
    Category of document (from 2022)V3 - Vedecký výstup publikačnej činnosti z časopisu
    Type of documentčlánok
    Year2019
    Registered inWOS
    Registered inSCOPUS
    DOI 10.1186/s40478-019-0770-y
    article

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    201920185.883Q13.279Q1
Number of the records: 1  

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