Počet záznamov: 1
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/ straight filaments
Názov Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/ straight filaments Autor Alonso A. Spoluautori Zaidi T. Novák Michal SAVNEIMU - Neuroimunologický ústav SAV SCOPUS Grundke-Iqbal I. Iqbal K. Zdroj.dok. Proceedings of the National Academy of Sciences of the United States of America. Vol. 98, (2001) p. 6923 - 6928 Jazyk dok. eng - angličtina Krajina SK - Slovenská republika Druh dok. rozpis článkov z periodík (rbx) Ohlasy MORALES-CORRALIZA, J. - MAZZELLA, M.J. - BERGER, J.D. - DIAZ, N.S. - CHOI, J.H.K. - LEVY, E. - MATSUOKA, Y. - PLANEL, E. - MATHEWS, P.M. In Vivo Turnover of Tau and APP Metabolites in the Brains of Wild-Type and Tg2576 Mice: Greater Stability of sAPP in the beta-Amyloid Depositing Mice. In PLOS ONE. ISSN 1932-6203, SEP 22 2009, vol. 4, no. 9. CAMPOS-PENA, V. - TAPIA-RAMIREZ, J. - SANCHEZ-TORRES, C. - MERAZ-RIOS, M.A. Pathological-Like Assembly of TAU Induced by a Paired Helical Filament Core Expressed at the Plasma Membrane. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2009, vol. 18, no. 4, p. 919-933. LING, K.H. - HEWITT, C.A. - BEISSBARTH, T. - HYDE, L. - BANERJEE, K. - CHEAH, P.S. - CANNON, P.Z. - HAHN, C.N. - THOMAS, P.Q. - SMYTH, G.K. - TAN, S.S. - THOMAS, T. - SCOTT, H.S. Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. In GENOME BIOLOGY. ISSN 1474-760X, 2009, vol. 10, no. 10. BJERKE, M. - ANDREASSON, U. - ROLSTAD, S. - NORDLUND, A. - LIND, K. - ZETTERBERG, H. - EDMAN, A. - BLENNOW, K. - WALLIN, A. Subcortical Vascular Dementia Biomarker Pattern in Mild Cognitive Impairment. In DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. ISSN 1420-8008, 2009, vol. 28, no. 4, p. 348-356. SCHNEIDER, P. - HAMPEL, H. - BUERGER, K. Biological Marker Candidates of Alzheimer's Disease in Blood, Plasma, and Serum. In CNS NEUROSCIENCE & THERAPEUTICS. ISSN 1755-5930, 2009, vol. 15, no. 4, p. 358-374. TAUPIN, P. Adult Neurogenesis, Neural Stem Cells and Alzheimer's Disease: Developments, Limitations, Problems and Promises. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, DEC 2009, vol. 6, no. 6, p. 461-470. ZHOU, Z. - FAN, J.B. - ZHU, H.L. - SHEWMAKER, F. - YAN, X. - CHEN, X. - CHEN, J. - XIAO, G.F. - GUO, L. - LIANG, Y. Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, OCT 30 2009, vol. 284, no. 44, p. 30148-30158. MCCONNELL, G.C. - REES, H.D. - LEVEY, A.I. - GUTEKUNST, C.A. - GROSS, R.E. - BELLAMKONDA, R.V. Implanted neural electrodes cause chronic, local inflammation that is correlated with local neurodegeneration. In JOURNAL OF NEURAL ENGINEERING. ISSN 1741-2560, OCT 2009, vol. 6, no. 5. VAN EERSEL, J. - BI, M.A. - KE, Y.D. - HODGES, J.R. - XUEREB, J.H. - GREGORY, G.C. - HALLIDAY, G.M. - GOTZ, J. - KRIL, J.J. - ITTNER, L.M. Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. In JOURNAL OF NEURAL TRANSMISSION. ISSN 0300-9564, OCT 2009, vol. 116, no. 10, p. 1243-1251. BARRANTES, A. - SOTRES, J. - HERNANDO-PEREZ, M. - BENITEZ, M.J. - DE PABLO, P.J. - BARO, A.M. - AVILA, J. - JIMENEZ, J.S. Tau Aggregation Followed by Atomic Force Microscopy and Surface Plasmon Resonance, and Single Molecule Tau-Tau Interaction Probed by Atomic Force Spectroscopy. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2009, vol. 18, no. 1, p. 141-151. KORENOVA, M. - STOZICKA, Z. Improved Behavioral Response as a Valid Biomarker for Drug Screening Program in Transgenic Rodent Models of Tauopathies. In CELLULAR AND MOLECULAR NEUROBIOLOGY. ISSN 0272-4340, SEP 2009, vol. 29, no. 6-7, p. 937-944. JUNG, T. - CATALGOL, B. - GRUNE, T. The proteasomal system. In MOLECULAR ASPECTS OF MEDICINE. ISSN 0098-2997, AUG 2009, vol. 30, no. 4, Sp. Iss. SI, p. 191-296. VIEIRA, S. - REBELO, S. - DOMINGUES, S. - SILVA, E.F.D.E. - SILVA, O.A.B.D.E. S655 phosphorylation enhances APP secretory traffic. In MOLECULAR AND CELLULAR BIOCHEMISTRY. ISSN 0300-8177, AUG 2009, vol. 328, no. 1-2, p. 145-154. MATHIEU, J.M. - SCHLOENDORN, J. - RITTMANN, B.E. - ALVAREZ, P.J.J. Medical bioremediation of age-related diseases. In MICROBIAL CELL FACTORIES. ISSN 1475-2859, APR 9 2009, vol. 8. AMNIAI, L. - BARBIER, P. - SILLEN, A. - WIERUSZESKI, J.M. - PEYROT, V. - LIPPENS, G. - LANDRIEU, I. Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules. In FASEB JOURNAL. ISSN 0892-6638, APR 2009, vol. 23, no. 4, p. 1146-1152. GENDRON, T.F. - PETRUCELLI, L. The role of tau in neurodegeneration. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, MAR 11 2009, vol. 4. TEZAPSIDIS, N. - JOHNSTON, J.M. - SMITH, M.A. - ASHFORD, J.W. - CASADESUS, G. - ROBAKIS, N.K. - WOLOZIN, B. - PERRY, G. - ZHU, X.W. - GRECO, S.J. - SARKAR, S. Leptin: A Novel Therapeutic Strategy for Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2009, vol. 16, no. 4, p. 731-740. ZHANG, Q.P. - ZHANG, X.G. - SUN, A.Y. Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models. In ACTA NEUROPATHOLOGICA. ISSN 0001-6322, JUN 2009, vol. 117, no. 6, p. 687-697. LIRA-DE LEON, K.I. - DE ANDA-HERNANDEZ, M.A. - CAMPOS-PENA, V. - MERAZ-RIOS, M.A. Plasma Membrane-Associated PHF-Core Could be the Trigger for Tau Aggregation in Alzheimer's Disease. In CURRENT HYPOTHESES AND RESEARCH MILESTONES IN ALZHEIMER'S DISEASE. 2009, p. 93-+. WOLFE, M.S. Tau Mutations in Neurodegenerative Diseases. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, MAR 6 2009, vol. 284, no. 10, p. 6021-6025. GRECO, S.J. - SARKAR, S. - JOHNSTON, J.M. - TEZAPSIDIS, N. Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells. In BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. ISSN 0006-291X, FEB 27 2009, vol. 380, no. 1, p. 98-104. ROHN, T.T. - HEAD, E. Caspase Activation in Alzheimer's Disease: Early to Rise and Late to Bed. In REVIEWS IN THE NEUROSCIENCES. ISSN 0334-1763, 2008, vol. 19, no. 6, p. 383-393. SAHARA, N. - MAEDA, S. - TAKASHIMA, A. Tau Oligomerization: A Role for Tau Aggregation Intermediates Linked to Neurodegeneration. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, DEC 2008, vol. 5, no. 6, p. 591-598. KROLAK-SALMON, P. - SEGUIN, J. - PERRET-LIAUDET, A. - DESESTRET, V. - VIGHETTO, A. - BONNEFOY, M. Near a biological diagnosis of Alzheimer's disease and related disorders. In REVUE DE MEDECINE INTERNE. ISSN 0248-8663, OCT 2008, vol. 29, no. 10, p. 785-793. HIRATA-FUKAE, C. - LI, H.F. - MA, L. - HOE, H.S. - REBECK, G.W. - AISEN, P.S. - MATSUOKA, Y. Levels of soluble and insoluble tau reflect overall status of tau phosphorylation in vivo. In NEUROSCIENCE LETTERS. ISSN 0304-3940, JAN 23 2009, vol. 450, no. 1, p. 51-55. GUERRERO, R. - NAVARRO, P. - GALLEGO, E. - GARCIA-CABRERO, A.M. - AVILA, J. - SANCHEZ, M.P. Hyperphosphorylated tau aggregates in the cortex and hippocampus of transgenic mice with mutant human FTDP-17 Tau and lacking the PARK2 gene. In ACTA NEUROPATHOLOGICA. ISSN 0001-6322, FEB 2009, vol. 117, no. 2, p. 159-168. DONNELLY, A. - BLAGG, B.S.J. Novobiocin and Additional Inhibitors of the Hsp90 C-Terminal Nucleotide-binding Pocket. In CURRENT MEDICINAL CHEMISTRY. ISSN 0929-8673, NOV 2008, vol. 15, no. 26, p. 2702-2717. NAVARRO, R. - GUERRERO, R. - GALLEGO, E. - AVILA, J. - LUQUIN, R. - RUIZ, P.J.G. - SANCHEZ, M.R. Motor alterations are reduced in mice lacking the PARK2 gene in the presence of a human FTDP-17 mutant form of four-repeat tau. In JOURNAL OF THE NEUROLOGICAL SCIENCES. ISSN 0022-510X, DEC 15 2008, vol. 275, no. 1-2, p. 139-144. LIPPENS, G. - SILLEN, A. - LANDRIEU, I. - AMNIAI, L. - SIBILLE, N. - BARBIER, P. - LEROY, A. - HANOULLE, X. - WIERUSZESKI, J.M. Tau Aggregation in Alzheimer's Disease What Role for Phosphorylation?. In PRION. ISSN 1933-6896, JAN-MAR 2007, vol. 1, no. 1, p. 21-25. ENGEL, T. - GONI-OLIVER, P. - GOMEZ-RAMOS, P. - MORAN, M.A. - LUCAS, J.J. - AVILA, J. - HERNANDEZ, F. HIPPOCAMPAL NEURONAL SUBPOPULATIONS ARE DIFFERENTIALLY AFFECTED IN DOUBLE TRANSGENIC MICE OVEREXPRESSING FRONTOTEMPORAL DEMENTIA AND PARKINSONISM LINKED TO CHROMOSOME 17 TAU AND GLYCOGEN SYNTHASE KINASE-3 beta. In NEUROSCIENCE. ISSN 0306-4522, DEC 10 2008, vol. 157, no. 4, p. 772-780. SADIK, G. - TANAKA, T. - KATO, K. - YAMAMORI, H. - NESSA, B.N. - MORIHARA, T. - TAKEDA, M. Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: implications for the mechanism of tau aggregation. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, JAN 2009, vol. 108, no. 1, p. 33-43. PLANEL, E. - KRISHNAMURTHY, P. - MIYASAKA, T. - LIU, L. - HERMAN, M. - KUMAR, A. - BRETTEVILLE, A. - FIGUEROA, H.Y. - YU, W.H. - WHITTINGTON, R.A. - DAVIES, P. - TAKASHIMA, A. - NIXON, R.A. - DUFF, K.E. Anesthesia-Induced Hyperphosphorylation Detaches 3-Repeat Tau from Microtubules without Affecting Their Stability In Vivo. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, NOV 26 2008, vol. 28, no. 48, p. 12798-12807. HERNANDEZ, F. - AVILA, J. The role of glycogen synthase kinase 3 in the early stages of Alzheimers' disease. In FEBS LETTERS. ISSN 0014-5793, NOV 26 2008, vol. 582, no. 28, p. 3848-3854. INOUE, M. - HIRATA, A. - TAINAKA, K. - MORII, T. - KONNO, T. Charge-Pairing Mechanism of Phosphorylation Effect upon Amyloid Fibrillation of Human Tau Core Peptide. In BIOCHEMISTRY. ISSN 0006-2960, NOV 11 2008, vol. 47, no. 45, p. 11847-11857. KONDZIELLA, D. - ZETTERBERG, H. Hyperphosphorylation of tau protein in superficial CNS siderosis. In JOURNAL OF THE NEUROLOGICAL SCIENCES. ISSN 0022-510X, OCT 15 2008, vol. 273, no. 1-2, p. 130-132. MASTRANGELO, M.A. - BOWERS, W.J. Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice. In BMC NEUROSCIENCE. ISSN 1471-2202, AUG 12 2008, vol. 9. YU, C.H. - SI, T. - WU, W.H. - HU, J. - DU, J.T. - ZHAO, Y.F. - LI, Y.M. O-GlcNAcylation modulates the self-aggregation ability of the fourth microtubule-binding repeat of tau. In BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. ISSN 0006-291X, OCT 10 2008, vol. 375, no. 1, p. 59-62. FILIPEK, A. - SCHNEIDER, G. - MIETELSKA, A. - FIGIEL, I. - NIEWIADOMSKA, G. Age-dependent changes in neuronal distribution of CacyBP/SIP: comparison to tubulin and the tau protein. In JOURNAL OF NEURAL TRANSMISSION. ISSN 0300-9564, SEP 2008, vol. 115, no. 9, p. 1257-1264. PEI, J.J. - BJORKDAHL, C. - ZHANG, H.Y. - ZHOU, X.W. - WINBLAD, B. p70 S6 kinase and tau in Alzheimer's disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2008, vol. 14, no. 4, p. 385-392. RANKIN, C.A. - GAMBLIN, T.C. Assessing the toxicity of tau aggregation. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2008, vol. 14, no. 4, p. 411-416. BRETTEVILLE, A. - PLANEL, E. Tau aggregates: Toxic, inert, or protective species?. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2008, vol. 14, no. 4, p. 431-436. DING, H.P. - JOHNSON, G.V.W. The last tangle of tau. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2008, vol. 14, no. 4, p. 441-447. DING, H.P. - DOLAN, P.J. - JOHNSON, G.V.W. Histone deacetylase 6 interacts with the microtubule-associated protein tau. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, SEP 2008, vol. 106, no. 5, p. 2119-2130. DING, H.P. - JOHNSON, G.V.W. New application of beta-galactosidase complementation to monitor tau self-association. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, AUG 2008, vol. 106, no. 4, p. 1545-1551. WINDERICKX, J. - DELAY, C. - DE VOS, A. - KLINGER, H. - PELLENS, K. - VANHELMONT, T. - VAN LEUVEN, F. - ZABROCKI, P. Protein folding diseases and neurodegeneration: Lessons learned from yeast. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. ISSN 0167-4889, JUL 2008, vol. 1783, no. 7, p. 1381-1395. REZAI-ZADEH, K. - ARENDASH, G.W. - HOU, H.Y. - FERNANDEZ, F. - JENSEN, M. - RUNFELDT, M. - SHYTLE, R.D. - TAN, J. Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice. In BRAIN RESEARCH. ISSN 0006-8993, JUN 12 2008, vol. 1214, p. 177-187. WANG, J.Z. - LIU, F. Microtubule-associated protein tau in development, degeneration and protection of neurons. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, JUN 2008, vol. 85, no. 2, p. 148-175. HUBINGER, G. - GEIS, S. - LECORRE, S. - MUHLBACHER, S. - GORDON, S. - FRACASSO, R.P. - HOFFMAN, F. - FERRAND, S. - KLAFKI, H.W. - RODER, H.M. Inhibition of PHF-like tau hyperphosphorylation in SH-SY5Y cells and rat brain slices by K252a. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, APR 2008, vol. 13, no. 3, p. 281-294. UVERSKY, V.N. Amyloidogenesis of natively unfolded proteins. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, JUN 2008, vol. 5, no. 3, p. 260-287. RAMALHO, R.M. - VIANA, R.J.S. - CASTRO, R.E. - STEER, C.J. - LOW, W.C. - RODRIGUES, C.M.P. Apoptosis in Transgenic mice expressing the P301L mutated form of human tau. In MOLECULAR MEDICINE. ISSN 1076-1551, MAY-JUN 2008, vol. 14, no. 5-6, p. 309-317. CONGDON, E.E. - KIM, S. - BONCHAK, J. - SONGRUG, T. - MATZAVINOS, A. - KURET, J. Nucleation-dependent tau filament formation - The importance of dimerization and an estimation of elementary rate constants. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, MAY 16 2008, vol. 283, no. 20, p. 13806-13816. NAVARRO, P. - GUERRERO, R. - GALLEGO, E. - AVILA, J. - LUQUIN, R. - RUIZ, P.J.G. - SANCHEZ, M.P. Memory and exploratory impairment in mice that lack the Park-2 gene and that over-express the human FTDP-17 mutant Tau. In BEHAVIOURAL BRAIN RESEARCH. ISSN 0166-4328, JUN 3 2008, vol. 189, no. 2, p. 350-356. GUERRERO, R. - NAVARRO, P. - GALLEGO, E. - AVILA, J. - DE YEBENES, J.G. - SANCHEZ, M.P. Park2-null/tau transgenic mice reveal a functional relationship between parkin and tau. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2008, vol. 13, no. 2, p. 161-172. PRASAD, K.K. - VERMA, S. Facilitation of peptide fibre formation by arginine-phosphate/carboxylate interactions. In JOURNAL OF CHEMICAL SCIENCES. ISSN 0253-4134, JAN 2008, vol. 120, no. 1, p. 155-162. MONDRAGON-RODRIGUEZ, S. - BASURTO-ISLAS, G. - SANTA-MARIA, I. - MENA, R. - BINDER, L.I. - AVILA, J. - SMITH, M.A. - PERRY, G. - GARCIA-SIERRA, F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. ISSN 0959-9673, APR 2008, vol. 89, no. 2, p. 81-90. MONDRAGON-RODRIGUEZ, S. - MENA, R. - BINDER, L.I. - SMITH, M.A. - PERRY, G. - GARCIA-SIERRA, F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. In NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. ISSN 0305-1846, FEB 2008, vol. 34, no. 1, p. 62-75. PLANEL, E. - TATEBAYASHI, Y. - MIYASAKA, T. - LIU, L. - WANG, L.L. - HERMAN, M. - YU, W.H. - LUCHSINGER, J.A. - WADZINSKI, B. - DUFF, K.E. - TAKASHIMA, A. Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, DEC 12 2007, vol. 27, no. 50, p. 13635-13648. CHUN, W.J. - WALDO, G.S. - JOHNSON, G.V.W. Split GFP complementation assay: a novel approach to quantitatively measure aggregation of tau in situ: effects of GSK3 beta activation and caspase 3 cleavage. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, DEC 2007, vol. 103, no. 6, p. 2529-2539. ORLACCHIO, A. - BERNARDI, G. - ORLACCHI, A. - MARTIN, S. RNA interference as a tool for Alzheimer's disease therapy. In MINI-REVIEWS IN MEDICINAL CHEMISTRY. ISSN 1389-5575, NOV 2007, vol. 7, no. 11, p. 1166-1176. DU, J.T. - YU, C.H. - ZHOU, L.X. - WU, W.H. - LEI, P. - LI, Y. - ZHAO, Y.F. - NAKANISHI, H. - LI, Y.M. Phosphorylation modulates the local conformation and self-aggregation ability of a peptide from the fourth tau microtubule-binding repeat. In FEBS JOURNAL. ISSN 1742-464X, OCT 2007, vol. 274, no. 19, p. 5012-5020. CARLSON, S.W. - BRANDEN, M. - VOSS, K. - SUN, Q. - RANKIN, C.A. - GAMBLIN, T.C. A complex mechanism for inducer mediated tau polymerization. In BIOCHEMISTRY. ISSN 0006-2960, JUL 31 2007, vol. 46, no. 30, p. 8838-8849. REBELO, S. - VIEIRA, S.I. - ESSELMANN, H. - WILTFANG, J. - SILVA, E.F.D.E. - SILVA, O.A.B.D.E. Tyrosine 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits decreased turnover rate. In NEURODEGENERATIVE DISEASES. ISSN 1660-2854, 2007, vol. 4, no. 2-3, p. 78-87. GASPARINI, L. - TERNI, B. - SPILLANTINI, M.G. Frontotemporal dementia with tau pathology. In NEURODEGENERATIVE DISEASES. ISSN 1660-2854, 2007, vol. 4, no. 2-3, p. 236-253. GALLO, J.M. - NOBLE, W. - MARTIN, T.R. RNA and protein-dependent mechanisms in tauopathies: consequences for therapeutic strategies. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, JUL 2007, vol. 64, no. 13, p. 1701-1714. ENGEL, T. - LUCAS, J.J. - HERNANDEZ, F. - AVILA, J. A mouse model to study tau pathology related with tau phosphorylation and assembly. In JOURNAL OF THE NEUROLOGICAL SCIENCES. ISSN 0022-510X, JUN 15 2007, vol. 257, no. 1-2, p. 250-254. CHUN, W. - JOHNSON, G.V.W. Activation of glycogen synthase kinase 3 beta promotes the intermolecular association of tau - The use of fluorescence resonance energy transfer microscopy. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, AUG 10 2007, vol. 282, no. 32, p. 23410-23417. BECKER, J.S. - PRZYBYLSKI, M. Studies of structure and phosphorylation of tau protein using high resolution mass spectrometry. In JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY. ISSN 0267-9477, 2007, vol. 22, no. 7, p. 761-765. SAHARA, N. - MAEDA, S. - MURAYAMA, M. - SUZUKI, T. - DOHMAE, N. - YEN, S.H. - TAKASHIMA, A. Assembly of two distinct dimers and higher-order oligomers from full-length tau. In EUROPEAN JOURNAL OF NEUROSCIENCE. ISSN 0953-816X, MAY 2007, vol. 25, no. 10, p. 3020-3029. UENO, H. - MURAYAMA, O. - MAEDA, S. - SAHARA, N. - PARK, J.M. - MURAYAMA, M. - SANDA, A. - IWAHASHI, K. - MATSUDA, M. - TAKASHIMA, A. Novel conformation-sensitive antibodies specific to three- and four-repeat tau. In BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. ISSN 0006-291X, JUN 29 2007, vol. 358, no. 2, p. 602-607. BANDYOPADHYAY, B. - LI, G.B. - YIN, H.S. - KURET, J. Tau aggregation and toxicity in a cell culture model of tauopathy. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, JUN 1 2007, vol. 282, no. 22, p. 16454-16464. PLANEL, E. - RICHTER, K.E.G. - NOLAN, C.E. - FINLEY, J.E. - LIU, L. - WEN, Y. - KRISHNAMURTHY, P. - HERMAN, M. - WANG, L.L. - SCHACHTER, J.B. - NELSON, R.B. - LAU, L.F. - DUFF, K.E. Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, MAR 21 2007, vol. 27, no. 12, p. 3090-3097. KUHLA, B. - HAASE, C. - FLACH, K. - LUTH, H.J. - ARENDT, T. - MUNCH, G. Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on Tau aggregation and filament formation. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, MAR 9 2007, vol. 282, no. 10, p. 6984-6991. RODER, H.M. - HUTTON, M.L. Microtubule-associated protein tau as a therapeutic target in neurodegenerative disease. In EXPERT OPINION ON THERAPEUTIC TARGETS. ISSN 1472-8222, APR 2007, vol. 11, no. 4, p. 435-442. NIEWIADOMSKA, G. - BAKSALERSKA-PAZERA, M. - RIEDEL, G. Cytoskeletal transport in the aging brain: Focus on the cholinergic system. In REVIEWS IN THE NEUROSCIENCES. ISSN 0334-1763, 2006, vol. 17, no. 6, p. 581-618. CHUN, W. - JOHNSON, G.V.W. The role of tau phosphorylation and cleavage in neuronal cell death. In FRONTIERS IN BIOSCIENCE. ISSN 1093-9946, JAN 1 2007, vol. 12, p. 733-756. LEROY, K. - YILMAZ, Z. - BRION, J.P. Increased level of active GSK-3 beta in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration. In NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. ISSN 0305-1846, FEB 2007, vol. 33, no. 1, p. 43-55. TSUKANE, M. - YOSHIZAKI, C. - YAMAUCHI, T. Development and specific induction of apoptosis of cultured cell models overexpressing human tau during neural differentiation: Implication in Alzheimer's disease. In ANALYTICAL BIOCHEMISTRY. ISSN 0003-2697, JAN 1 2007, vol. 360, no. 1, p. 114-122. ENGEL, T. - GONI-OLIVER, P. - LUCAS, J.J. - AVILA, J. - HERNANDEZ, F. Chronic lithium administration to FTDP-17 tau and GSK-3 beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, DEC 2006, vol. 99, no. 6, p. 1445-1455. ZHANG, X. - ZHANG, Y.W. - LIU, S.J. - BULLOJ, A. - TONG, G.G. - ZHANG, Z.H. - LIAO, F.F. - XU, H.X. Tumor suppressor PTEN affects tau phosphorylation: deficiency in the phosphatase activity of PTEN increases aggregation of an FTDP-17 mutant Tau. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, 2006, vol. 1. LIU, F. - LIANG, Z. - GONG, C.X. Hyperphosphorylation of tau and protein phosphatases in Alzheimer disease. In PANMINERVA MEDICA. ISSN 0031-0808, JUN 2006, vol. 48, no. 2, p. 97-108. ZHANG, X. - LI, F. - BULLOJ, A. - ZHANG, Y.W. - TONG, G. - ZHANG, Z.H. - LIAO, F.F. - XU, H.X. Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubules. In FASEB JOURNAL. ISSN 0892-6638, JUN 2006, vol. 20, no. 8, p. 1272-+. SANTA-MARIA, I. - PEREZ, M. - HERNANDEZ, F. - MUNOZ, V. - MORENO, F.J. - AVILA, J. In vitro tau fibrillization: Mapping protein regions. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, JUL 2006, vol. 1762, no. 7, p. 683-692. ZHOU, L.X. - ZENG, Z.Y. - DU, J.T. - ZHAO, Y.F. - LI, Y.M. The self-assembly ability of the first microtubule-binding repeat from tau and its modulation by phosphorylation. In BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. ISSN 0006-291X, SEP 22 2006, vol. 348, no. 2, p. 637-642. SATO, S. - CERNY, R.L. - BUESCHER, J.L. - IKEZU, T. Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, SEP 2006, vol. 98, no. 5, p. 1573-1584. DING, H.P. - MATTHEWS, T.A. - JOHNSON, G.V.W. Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, JUL 14 2006, vol. 281, no. 28, p. 19107-19114. MONACO, S. - ZANUSSO, G. - MAZZUCCO, S. - RIZZUTO, N. Cerebral amyloidoses: Molecular pathways and therapeutic challenges. In CURRENT MEDICINAL CHEMISTRY. ISSN 0929-8673, 2006, vol. 13, no. 16, p. 1903-1913. SULTANA, R. - BOYD-KIMBALL, D. - POON, H.F. - CAI, J. - PIERCE, W.M. - KLEIN, J.B. - MARKESBERY, W.R. - ZHOU, X.Z. - LU, K.P. - BUTTERFIELD, D.A. Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, JUL 2006, vol. 27, no. 7, p. 918-925. RUBIO, A. - PEREZ, M. - AVILA, J. Acetylcholine receptors and tau phosphorylation. In CURRENT MOLECULAR MEDICINE. ISSN 1566-5240, JUN 2006, vol. 6, no. 4, p. 423-428. CRIPPS, D. - THOMAS, S.N. - JENG, Y. - YANG, F. - DAVIES, P. - YANG, A.J. Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, APR 21 2006, vol. 281, no. 16, p. 10825-10838. LANDRIEU, I. - LACOSSE, L. - LEROY, A. - WIERUSZESKI, J.M. - TRIVELLI, X. - SILLEN, A. - SIBILLE, N. - SCHWALBE, H. - SAXENA, K. - LANGER, T. - LIPPENS, G. NMR analysis of a Tau phosphorylation pattern. In JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. ISSN 0002-7863, MAR 22 2006, vol. 128, no. 11, p. 3575-3583. LIPPENS, G. - SILLEN, A. - SMET, C. - WIERUSZESKI, J.M. - LEROY, A. - BUEE, L. - LANDRIEU, I. Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy. In PROTEIN AND PEPTIDE LETTERS. ISSN 0929-8665, 2006, vol. 13, no. 3, p. 235-246. TSUKANE, M. - YAMAUCHI, T. Increase in apoptosis with neural differentiation and shortening of the lifespan of P19 cells overexpressing tau. In NEUROCHEMISTRY INTERNATIONAL. ISSN 0197-0186, MAR 2006, vol. 48, no. 4, p. 243-254. INOUYE, H. - SHARMA, D. - GOUX, W.J. - KIRSCHNER, D.A. Structure of core domain of fibril-forming PHF/Tau fragments. In BIOPHYSICAL JOURNAL. ISSN 0006-3495, MAR 2006, vol. 90, no. 5, p. 1774-1789. XIAO, J.F. - GUO, Z.R. - GUO, Y.S. - CHU, F.M. - SUN, P.Y. Inhibitory mode of N-phenyl-4-pyrazolo[1,5-b] pyridazin-3-ylpyrimidin-2-amine series derivatives against GSK-3: molecular docking and 3D-QSAR analyses. In PROTEIN ENGINEERING DESIGN & SELECTION. ISSN 1741-0126, FEB 2006, vol. 19, no. 2, p. 47-54. PEI, J.J. - AN, W.L. - ZHOU, X.W. - NISHIMURA, T. - NORBERG, J. - BENEDIKZ, E. - GOTZ, J. - WINBLAD, B. P70S6 kinase mediates tau phosphorylation and synthesis. In FEBS LETTERS. ISSN 0014-5793, JAN 9 2006, vol. 580, no. 1, p. 107-114. D'AMBROSIO, C. - ARENA, S. - FULCOLI, G. - SCHEINFELD, M.H. - ZHOU, D.W. - D'ADAMIO, L. - SCALONI, A. Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease. In MOLECULAR & CELLULAR PROTEOMICS. ISSN 1535-9476, JAN 2006, vol. 5, no. 1, p. 97-113. NAKASHIMA, H. - ISHIHARA, T. - SUGUIMOTO, P. - YOKOTA, O. - OSHIMA, E. - KUGO, A. - TERADA, S. - HAMAMURA, T. - TROJANOWSKI, J.Q. - LEE, V.M.Y. - KURODA, S. Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies. In ACTA NEUROPATHOLOGICA. ISSN 0001-6322, DEC 2005, vol. 110, no. 6, p. 547-556. ELLIOTT, E. - ATLAS, R. - LANGE, A. - GINZBURG, I. Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3Kinase signalling mechanism. In EUROPEAN JOURNAL OF NEUROSCIENCE. ISSN 0953-816X, SEP 2005, vol. 22, no. 5, p. 1081-1089. VANDEBROEK, T. - VANHELMONT, T. - TERWEL, D. - BORGHGRAEF, P. - LEMAIRE, K. - SNAUWAERT, J. - WERA, S. - VAN LEUVEN, F. - WINDERICKX, J. Identification and isolation of a hyperphosphorylated, conformationally changed intermediate of human protein tau expressed in yeast. In BIOCHEMISTRY. ISSN 0006-2960, AUG 30 2005, vol. 44, no. 34, p. 11466-11475. KURET, J. - CONGDON, E.E. - LI, G.B. - YIN, H.H. - YU, X. - ZHONG, Q. Evaluating triggers and enhancers of tau fibrillization. In MICROSCOPY RESEARCH AND TECHNIQUE. ISSN 1059-910X, JUL 2005, vol. 67, no. 3-4, p. 141-155. DUFF, K. - PLANEL, E. Untangling memory deficits. In NATURE MEDICINE. ISSN 1078-8956, AUG 2005, vol. 11, no. 8, p. 826-827. CHIRITA, C.N. - CONGDON, E.E. - YIN, H.S. - KURET, J. Triggers of full-length tau aggregation: A role for partially folded interrnediates. In BIOCHEMISTRY. ISSN 0006-2960, APR 19 2005, vol. 44, no. 15, p. 5862-5872. GEDDES, J.W. alpha-Synuclein: A potent inducer of tau pathology. In EXPERIMENTAL NEUROLOGY. ISSN 0014-4886, APR 2005, vol. 192, no. 2, p. 244-250. NECULA, M. - KURET, J. Site-specific pseudophosphorylation modulates the rate of tau filament dissociation. In FEBS LETTERS. ISSN 0014-5793, FEB 28 2005, vol. 579, no. 6, p. 1453-1457. GOZES, I. - DIVINSKI, I. The femtomolar-acting NAP interacts with microtubules: Novel aspects of astrocyte protection. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, DEC 2004, vol. 6, no. 6, p. S37-S41. COTMAN, C.W. - POON, W.W. - RISSMAN, R.A. - BLURTON-JONES, M. The role of caspase cleavage of tau in Alzheimer disease neuropathology. In JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. ISSN 0022-3069, FEB 2005, vol. 64, no. 2, p. 104-112. TERWEL, D. - LASRADO, R. - SNAUWAERT, J. - VANDEWEERT, E. - VAN HAESENDONCK, C. - BORGHGRAEF, P. - VAN LEUVEN, F. Changed conformation of mutant tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of tau-4R/2N transgenic mice. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, FEB 4 2005, vol. 280, no. 5, p. 3963-3973. KUMAR, V. - MADAN, A.K. Application of graph theory: prediction of glycogen synthase kinase-3 beta inhibitory activity of thiadiazolidinones as potential drugs for the treatment of Alzheimer's disease. In EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. ISSN 0928-0987, FEB 2005, vol. 24, no. 2-3, p. 213-218. PALOMO, T. - ARCHER, T. - BENINGER, R.J. - KOSTRZEWA, R.M. Gene-environment interplay in Neurogenesis and neurodegeneration. In NEUROTOXICITY RESEARCH. ISSN 1029-8428, 2004, vol. 6, no. 6, p. 415-434. GAMBLIN, T.C. Potential structure/function relationships of predicted secondary structural elements of tau. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, JAN 3 2005, vol. 1739, no. 2-3, p. 140-149. VON BERGEN, M. - BARGHORN, S. - BIERNAT, J. - MANDELKOW, E.M. - MANDELKOW, E. Tau aggregation is driven by a transition from random coil to beta sheet structure. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, JAN 3 2005, vol. 1739, no. 2-3, p. 158-166. KURET, J. - CHIRITA, C.N. - CONGDON, E.E. - KANNANAYAKAL, T. - LI, G.B. - NECULA, M. - YIN, H.S. - ZHONG, Q. Pathways of tau fibrillization. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, JAN 3 2005, vol. 1739, no. 2-3, p. 167-178. HALL, G.F. - YAO, J. Modeling tauopathy: a range of complementary approaches. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, JAN 3 2005, vol. 1739, no. 2-3, p. 224-239. BRANDT, R. - HUNDELT, M. - SHAHANI, N. Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, JAN 3 2005, vol. 1739, no. 2-3, p. 331-354. PEREZ, M. - RIBE, E. - RUBIO, A. - LIM, F. - MORAN, M.A. - RAMOS, P.G. - FERRER, I. - ISLA, M.T.G. - AVILA, J. Characterization of a double (amyloid precursor protein-tau) transgenic: Tau phosphorylation and aggregation. In NEUROSCIENCE. ISSN 0306-4522, 2005, vol. 130, no. 2, p. 339-347. NECULA, M. - KURET, J. Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, NOV 26 2004, vol. 279, no. 48, p. 49694-49703. YOSHIZAKI, C. - TSUKANE, M. - YAMAUCHI, T. Overexpression of tau leads to the stimulation of neurite outgrowth, the activation of caspase 3 activity, and accumulation and phosphorylation of tau in neuroblastoma cells on cAMP treatment. In NEUROSCIENCE RESEARCH. ISSN 0168-0102, AUG 2004, vol. 49, no. 4, p. 363-371. RISSMAN, R.A. - POON, W.W. - BLURTON-JONES, M. - ODDO, S. - TORP, R. - VITEK, M.P. - LAFERLA, F.M. - ROHN, T.T. - COTMAN, C.W. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. In JOURNAL OF CLINICAL INVESTIGATION. ISSN 0021-9738, JUL 2004, vol. 114, no. 1, p. 121-130. TIAN, Q. - LIN, Z.Q. - WANG, X.C. - CHEN, J. - WANG, Q. - GONG, C.X. - WANG, J.Z. Injection of okadaic acid into the Meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit. In NEUROSCIENCE. ISSN 0306-4522, 2004, vol. 126, no. 2, p. 277-284. LU, K.P. Pinning down cell signaling, cancer and Alzheimer's disease. In TRENDS IN BIOCHEMICAL SCIENCES. ISSN 0968-0004, APR 2004, vol. 29, no. 4, p. 200-209. AVILA, J. - LUCAS, J.J. - PEREZ, M. - HERNANDEZ, F. Role of tau protein in both physiological and pathological conditions. In PHYSIOLOGICAL REVIEWS. ISSN 0031-9333, APR 2004, vol. 84, no. 2, p. 361-384. LEE, V.M.Y. - GIASSON, B.I. - TROJANOWSKI, J.Q. More than just two peas in a pod: common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases. In TRENDS IN NEUROSCIENCES. ISSN 0166-2236, MAR 2004, vol. 27, no. 3, p. 129-134. PLANEL, E. - MIYASAKA, T. - LAUNEY, T. - CHUI, D.H. - TANEMURA, K. - SATO, S. - MURAYAMA, O. - ISHIGURO, K. - TATEBAYASHI, Y. - TAKASHIMA, A. Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: Implications for Alzheimer's disease. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, MAR 10 2004, vol. 24, no. 10, p. 2401-2411. SANTA-MARIA, I. - HERNANDEZ, F. - MARTIN, C.P. - AVILA, J. - MORENO, F.J. Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers. In BIOCHEMISTRY. ISSN 0006-2960, MAR 16 2004, vol. 43, no. 10, p. 2888-2897. GOEDERT, M. Tau protein and neurodegeneration. In SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. ISSN 1084-9521, FEB 2004, vol. 15, no. 1, p. 45-49. CHIRITA, C.N. - KURET, J. Evidence for an intermediate in tau filament formation. In BIOCHEMISTRY. ISSN 0006-2960, FEB 17 2004, vol. 43, no. 6, p. 1704-1714. CANU, N. - CALISSANO, P. In vitro cultured neurons for molecular studies correlating apoptosis with events related to Alzheimer disease. In CEREBELLUM. ISSN 1473-4222, 2003, vol. 2, no. 4, p. 270-278. LAU, L.F. - AHLIJANIAN, M.K. Role of cdk5 in the pathogenesis of Alzheimer's disease. In NEUROSIGNALS. ISSN 1424-862X, 2003, vol. 12, no. 4-5, p. 209-214. GAMBLIN, T.C. - BERRY, R.W. - BINDER, L.I. Modeling Tau polymerization in vitro: A review and synthesis. In BIOCHEMISTRY. ISSN 0006-2960, DEC 30 2003, vol. 42, no. 51, p. 15009-15017. SHULMAN, J.M. - FEANY, M.B. Genetic modifiers of tauopathy in Drosophila. In GENETICS. ISSN 0016-6731, NOV 2003, vol. 165, no. 3, p. 1233-1242. SCHEFF, S.W. - PRICE, D.A. Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, DEC 2003, vol. 24, no. 8, p. 1029-1046. PHINNEY, A.L. - HORNE, P. - YANG, J. - JANUS, C. - BERGERON, C. - WESTAWAY, D. Mouse models of Alzheimer's disease: The long and filamentous road. In NEUROLOGICAL RESEARCH. ISSN 0161-6412, SEP 2003, vol. 25, no. 6, p. 590-600. OHM, T.G. - GLOCKNER, F. - DISTL, R. - TREIBER-HELD, S. - MESKE, V. - SCHONHEIT, B. Plasticity and the spread of Alzheimer's disease-like changes. In NEUROCHEMICAL RESEARCH. ISSN 0364-3190, NOV 2003, vol. 28, no. 11, p. 1715-1723. HAMDANE, M. - SAMBO, A.V. - DELOBEL, P. - BEGARD, S. - VIOLLEAU, A. - DELACOURTE, A. - BERTRAND, P. - BENAVIDES, J. - BUEE, L. Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, SEP 5 2003, vol. 278, no. 36, p. 34026-34034. GAMBLIN, T.C. - CHEN, F. - ZAMBRANO, A. - ABRAHA, A. - LAGALWAR, S. - GUILLOZET, A.L. - LU, M.L. - FU, Y.F. - GARCIA-SIERRA, F. - LAPOINTE, N. - MILLER, R. - BERRY, R.W. - BINCLER, L.I. - CRYNS, V.L. Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease. In PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ISSN 0027-8424, AUG 19 2003, vol. 100, no. 17, p. 10032-10037. ANGELO, M. - PLATTNER, F. - IRVINE, E.E. - GIESE, K.P. Improved reversal learning and altered fear conditioning in transgenic mice with regionally restricted p25 expression. In EUROPEAN JOURNAL OF NEUROSCIENCE. ISSN 0953-816X, JUL 2003, vol. 18, no. 2, p. 423-431. CHIRITA, C.N. - NECULA, M. - KURET, J. Anionic micelles and vesicles induce tau fibrillization in vitro. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, JUL 11 2003, vol. 278, no. 28, p. 25644-25650. RODER, H.M. Prospect of therapeutic approaches to tauopathies. In JOURNAL OF MOLECULAR NEUROSCIENCE. ISSN 0895-8696, APR 2003, vol. 20, no. 2, p. 197-201. NOBLE, W. - OLM, V. - TAKATA, K. - CASEY, E. - O, M. - MEYERSON, J. - GAYNOR, K. - LAFRANCOIS, J. - WANG, L.L. - KONDO, T. - DAVIES, P. - BURNS, M. - NIXON, V.R. - DICKSON, D. - MATSUOKA, Y. - AHLIJANIAN, M. - LAU, L.F. - DUFF, K. Cdk5 is a key factor in tau aggregation and tangle formation in vivo. In NEURON. ISSN 0896-6273, MAY 22 2003, vol. 38, no. 4, p. 555-565. LU, K.P. - LIOU, Y.C. - VINCENT, I. Proline-directed phosphorylation and isomerization in mitotic regulation and in Alzheimer's Disease. In BIOESSAYS. ISSN 0265-9247, FEB 2003, vol. 25, no. 2, p. 174-181. TAKAHASHI, M. - KANUKA, H. - FUJIWARA, H. - KOYAMA, A. - HASEGAWA, M. - MIURA, M. - IWATSUBO, T. Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila. In NEUROSCIENCE LETTERS. ISSN 0304-3940, JAN 23 2003, vol. 336, no. 3, p. 155-158. GOZES, I. Tau as a drug target in Alzheimer's disease. In JOURNAL OF MOLECULAR NEUROSCIENCE. ISSN 0895-8696, DEC 2002, vol. 19, no. 3, p. 337-338. GIASSON, B.I. - SAMPATHU, D.M. - WILSON, C.A. - VOGELSBERG-RAGAGLIA, V. - MUSHYNSKI, W.E. - LEE, V.M.Y. The environmental toxin arsenite induces tau hyperphosphorylation. In BIOCHEMISTRY. ISSN 0006-2960, DEC 24 2002, vol. 41, no. 51, p. 15376-15387. BU, B.T. - KLUNEMANN, H. - SUZUKI, K. - LI, J. - BIRD, T. - JIN, L.W. - VINCENT, I. Niemann-Pick disease type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, NOV 2002, vol. 11, no. 2, p. 285-297. SAHARA, N. - LEWIS, J. - DETURE, M. - MCGOWAN, E. - DICKSON, D.W. - HUTTON, M. - YEN, S.H. Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, DEC 2002, vol. 83, no. 6, p. 1498-1508. SHAHANI, N. - BRANDT, R. Functions and malfunctions of the tau proteins. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, OCT 2002, vol. 59, no. 10, p. 1668-1680. SATO, S. - TATEBAYASHI, Y. - AKAGI, T. - CHUI, D.H. - MURAYAMA, M. - MIYASAKA, T. - PLANEL, E. - TANEMURA, K. - SUN, X.Y. - HASHIKAWA, T. - YOSHIOKA, K. - ISHIGURO, K. - TAKASHIMA, A. Aberrant tau phosphorylation by glycogen synthase kinase-3 beta and JNK3 induces oligomeric tau fibrils in COS-7 cells. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, NOV 1 2002, vol. 277, no. 44, p. 42060-42065. TERWEL, D. - DEWACHTER, I. - VAN LEUVEN, F. Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease. In NEUROMOLECULAR MEDICINE. ISSN 1535-1084, 2002, vol. 2, no. 2, p. 151-165. PLANEL, E. - SUN, X.Y. - TAKASHIMA, A. Role of GSK-3 beta in Alzheimer's disease pathology. In DRUG DEVELOPMENT RESEARCH. ISSN 0272-4391, JUL 2002, vol. 56, no. 3, p. 491-510. YAMAMOTO, A. - SHIN, R.W. - HASEGAWA, K. - NAIKI, H. - SATO, H. - YOSHIMASU, F. - KITAMOTO, T. Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, SEP 2002, vol. 82, no. 5, p. 1137-1147. FORMAN, M.S. - ZHUKAREVA, V. - BERGERON, C. - CHIN, S.S.M. - GROSSMAN, M. - CLARK, C. - LEE, V.M.Y. - TROJANOWSKI, J.Q. Signature tau neuropathology in gray and white matter of corticobasal degeneration. In AMERICAN JOURNAL OF PATHOLOGY. ISSN 0002-9440, JUN 2002, vol. 160, no. 6, p. 2045-2053. VAFAI, S.B. - STOCK, J.B. Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease. In FEBS LETTERS. ISSN 0014-5793, MAY 8 2002, vol. 518, no. 1-3, p. 1-4. SUN, A.Y. - NGUYEN, X.V. - BING, G.Y. Comparative analysis of an improved thioflavin-S stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections. In JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. ISSN 0022-1554, APR 2002, vol. 50, no. 4, p. 463-472. MARTINEZ, A. - ALONSO, M. - CASTRO, A. - PEREZ, C. - MORENO, F.J. First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3 beta) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease. In JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623, MAR 14 2002, vol. 45, no. 6, p. 1292-1299. PEREZ, M. - HERNANDEZ, F. - GOMEZ-RAMOS, A. - SMITH, M. - PERRY, G. - AVILA, J. Formation of aberrant phosphotau fibrillar polymers in neural cultured cells. In EUROPEAN JOURNAL OF BIOCHEMISTRY. ISSN 0014-2956, MAR 2002, vol. 269, no. 5, p. 1484-1489. CHOI, J.Y. - SUNG, Y.M. - PARK, H.J. - HUR, E.H. - KIM, X.Y. - CHOI, E.Y. - PARK, J. - MIN, B.R. - KANG, S. - RHIM, R. Slowly-migrating alpha-synuclein forms are found in the brains of patients with Parkinsons disease. In KOREAN JOURNAL OF GENETICS. ISSN 0254-5934, DEC 2001, vol. 23, no. 4, p. 393-400. ATZORI, C. - GHETTI, B. - PIVA, R. - SRINIVASAN, A.N. - ZOLO, P. - DELISLE, M.B. - MIRRA, S.S. - MIGHELI, A. Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. In JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. ISSN 0022-3069, DEC 2001, vol. 60, no. 12, p. 1190-1197. REIERSEN, H. - REES, A.R. The hunchback and its neighbours: proline as an environmental modulator. In TRENDS IN BIOCHEMICAL SCIENCES. ISSN 0968-0004, NOV 2001, vol. 26, no. 11, p. 679-684. GOZES, I. Tau Pathology and Future Therapeutics. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, DEC 2010, vol. 7, no. 8, p. 685-696. WHITTINGTON, R.A. - PAPON, M.A. - CHOUINARD-DECORTE, F. - PLANEL, E. Hypothermia and Alzheimer's Disease Neuropathogenic Pathways. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, DEC 2010, vol. 7, no. 8, p. 717-725. THORSELL, A. - BJERKE, M. - GOBOM, J. - BRUNHAGE, E. - VANMECHELEN, E. - ANDREASEN, N. - HANSSON, O. - MINTHON, L. - ZETTERBERG, H. - BLENNOW, K. Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease. In BRAIN RESEARCH. ISSN 0006-8993, NOV 29 2010, vol. 1362, p. 13-22. VIEIRA, S.I. - REBELO, S. - ESSELMANN, H. - WILTFANG, J. - LAH, J. - LANE, R. - SMALL, S.A. - GANDY, S. - DA CRUZ E SILVA, E.F. - AB DA CRUZ E SILVA, O. Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, OCT 11 2010, vol. 5. PARK, Y.J. - JANG, Y. - KWON, Y.H. Protective effect of isoflavones against homocysteine-mediated neuronal degeneration in SH-SY5Y cells. In AMINO ACIDS. ISSN 0939-4451, AUG 2010, vol. 39, no. 3, p. 785-794. LU F - LI X - SUO A - ZHANG J. Inhibition of tau hyperphosphorylation and beta amyloid production in rat brain by oral administration of atorvastatin. In CHINESE MEDICAL JOURNAL. ISSN 0366-6999, JUL 20 2010, vol. 123, no. 14, p. 1864-1870. DOLAN, P.J. - JOHNSON, G.V.W. A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, JUL 16 2010, vol. 285, no. 29, p. 21978-21987. ZHANG, Z.H. - FANG, X.B. - XI, G.M. - LI, W.C. - LING, H.Y. - QU, P. Calcitonin gene-related peptide enhances CREB phosphorylation and attenuates tau protein phosphorylation in rat brain during focal cerebral ischemia/reperfusion. In BIOMEDICINE & PHARMACOTHERAPY. ISSN 0753-3322, JUL 2010, vol. 64, no. 6, p. 430-436. GUZEL, A. - KARASALIHOGLU, S. - AYLANC, H. - TEMIZOZ, O. - HICDONMEZ, T. Validity of serum tau protein levels in pediatric patients with minor head trauma. In AMERICAN JOURNAL OF EMERGENCY MEDICINE. ISSN 0735-6757, MAY 2010, vol. 28, no. 4, p. 399-403. MONDRAGON-RODRIGUEZ, S. - BASURTO-ISLAS, G. - LEE, H.g. - PERRY, G. - ZHU, X. - CASTELLANI, R.J. - SMITH, M.A. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. In EXPERT REVIEW OF NEUROTHERAPEUTICS. ISSN 1473-7175, MAY 2010, vol. 10, no. 5, p. 683-691. MERAZ-RIOS, M.A. - LIRA-DE LEON, K.I. - CAMPOS-PENA, V. - DE ANDA-HERNANDEZ, M.A. - MENA-LOPEZ, R. Tau oligomers and aggregation in Alzheimer's disease. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, MAR 2010, vol. 112, no. 6, p. 1353-1367. LOPES, J.P. - OLIVEIRA, C.R. - AGOSTINHO, P. Neurodegeneration in an A beta-induced model of Alzheimer's disease: the role of Cdk5. In AGING CELL. ISSN 1474-9718, FEB 2010, vol. 9, no. 1, p. 64-77. BRONCEL, M. - WAGNER, S.C. - PAUL, K. - HACKENBERGER, C.P.R. - KOKSCH, B. Towards understanding secondary structure transitions: phosphorylation and metal coordination in model peptides. In ORGANIC & BIOMOLECULAR CHEMISTRY. ISSN 1477-0520, 2010, vol. 8, no. 11, p. 2575-2579. ZHAO, J.H. - LIU, H.L. - CHUANG, C.K. - LIU, K.T. - TSAI, W.B. - HO, Y. Molecular dynamics simulations to investigate the stability and aggregation behaviour of the amyloid-forming peptide VQIVYK from tau protein. In MOLECULAR SIMULATION. ISSN 0892-7022, 2010, vol. 36, no. 13, p. 1013-1024. JIMENEZ, J.S. Protein-DNA Interaction at the Origin of Neurological Diseases: A Hypothesis. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2010, vol. 22, no. 2, p. 375-391. MICHEL, T.M. - GSELL, W. - KAESBAUER, L. - TATSCHNER, T. - SHELDRICK, A.J. - NEUNER, I. - SCHNEIDER, F. - GRUENBLATT, E. - RIEDERER, P. Increased Mitochondrial Aldehydedehydrogenase in the putamen of individuals with Alzheimer's disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2010, vol. 19, no. 4, p. 1295-1301. ROJO, L.E. - ALZATE-MORALES, J. - SAAVEDRA, I.N. - DAVIES, P. - MACCIONI, R.B. Selective Interaction of Lansoprazole and Astemizole with Tau Polymers: Potential New Clinical Use in Diagnosis of Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2010, vol. 19, no. 2, p. 573-589. LEROY, K. - ANDO, K. - HERAUD, C. - YILMAZ, Z. - AUTHELET, M. - BOEYNAEMS, J.M. - BUEE, L. - DE DECKER, R. - BRION, J.P. Lithium Treatment Arrests the Development of Neurofibrillary Tangles in Mutant Tau Transgenic Mice with Advanced Neurofibrillary Pathology. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2010, vol. 19, no. 2, p. 705-719. BRONCEL, M. - FALENSKI, J.A. - WAGNER, S.C. - HACKENBERGER, C.P.R. - KOKSCH, B. How Post-Translational Modifications Influence Amyloid Formation: A Systematic Study of Phosphorylation and Glycosylation in Model Peptides. In CHEMISTRY-A EUROPEAN JOURNAL. ISSN 0947-6539, 2010, vol. 16, no. 26, p. 7881-7888. ROMANO, S. - SORRENTINO, A. - DI PACE, A. L. - NAPPO, G. - MERCOGLIANO, C. - ROMANO, M. F. The Emerging Role of Large Immunophilin FK506 Binding Protein 51 in Cancer. In CURRENT MEDICINAL CHEMISTRY. ISSN 0929-8673, DEC 2011, vol. 18, no. 35, p. 5424-5429. GONG, Eun Ji - PARK, Hee Ra - KIM, Mi Eun - PIAO, Shunfu - LEE, Eunjin - JO, Dong-Gyu - CHUNG, Hae Young - HA, Nam-Chul - MATTSON, Mark P. - LEE, Jaewon. Morin attenuates tau hyperphosphorylation by inhibiting GSK3 beta. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, NOV 2011, vol. 44, no. 2, p. 223-230. SALMINEN, Antero - KAARNIRANTA, Kai - HAAPASALO, Annakaisa - SOININEN, Hilkka - HILTUNEN, Mikko. AMP-activated protein kinase: a potential player in Alzheimer's disease. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, AUG 2011, vol. 118, no. 4, p. 460-474. CAMACHO-ARROYO, Ignacio - GONZALEZ-ARENAS, Aliesha - ESPINOSA-RAYA, Judith - GABRIELA PINA-MEDINA, Ana - PICAZO, Ofir. Short- and long-term treatment with estradiol or progesterone modifies the expression of GFAP, MAP2 and Tau in prefrontal cortex and hippocampus. In LIFE SCIENCES. ISSN 0024-3205, JUL 18 2011, vol. 89, no. 3-4, p. 123-128. HUDSON, A. E. - HEMMINGS, H. C., Jr. Are anaesthetics toxic to the brain?. In BRITISH JOURNAL OF ANAESTHESIA. ISSN 0007-0912, JUL 2011, vol. 107, no. 1, p. 30-37. WHITEMAN, Ineka T. - MINAMIDE, Laurie S. - GOH, De Lian - BAMBURG, James R. - GOLDSBURY, Claire. Rapid Changes in Phospho-MAP/Tau Epitopes during Neuronal Stress: Cofilin-Actin Rods Primarily Recruit Microtubule Binding Domain Epitopes. In PLOS ONE. ISSN 1932-6203, JUN 28 2011, vol. 6, no. 6. LOPES, Joao P. - AGOSTINHO, Paula. Cdk5: Multitasking between physiological and pathological conditions. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, JUN 2011, vol. 94, no. 1, p. 49-63. ABDEL-SALAM, Omar M. E. Stem Cell Therapy for Alzheimer's Disease. In CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. ISSN 1871-5273, JUN 2011, vol. 10, no. 4, p. 459-485. WAXMAN, Elisa A. - GIASSON, Benoit I. Induction of Intracellular Tau Aggregation Is Promoted by alpha-Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, MAY 25 2011, vol. 31, no. 21, p. 7604-7618. SOTIROPOULOS, Ioannis - CATANIA, Caterina - PINTO, Lucilia G. - SILVA, Rui - POLLERBERG, G. Elizabeth - TAKASHIMA, Akihiko - SOUSA, Nuno - ALMEIDA, Osborne F. X. Stress Acts Cumulatively To Precipitate Alzheimer's Disease-Like Tau Pathology and Cognitive Deficits. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, MAY 25 2011, vol. 31, no. 21, p. 7840-7847. LI, Guoyi - JIANG, Huiyi - CHANG, Ming - XIE, Hongrong - HU, Linsen. HDAC6 alpha-tubulin deacetylase: A potential therapeutic target in neurodegenerative diseases. In JOURNAL OF THE NEUROLOGICAL SCIENCES. ISSN 0022-510X, MAY 15 2011, vol. 304, no. 1-2, p. 1-8. VORONKOV, Michael - BRAITHWAITE, Steven P. - STOCK, Jeffry B. Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's disease. In FUTURE MEDICINAL CHEMISTRY. ISSN 1756-8919, MAY 2011, vol. 3, no. 7, p. 821-833. POON, Wayne W. - BLURTON-JONES, Mathew - TU, Christina H. - FEINBERG, Leila M. - CHABRIER, Meredith A. - HARRIS, Joe W. - JEON, Noo Li - COTMAN, Carl W. beta-Amyloid impairs axonal BDNF retrograde trafficking. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, MAY 2011, vol. 32, no. 5, p. 821-833. KIM, Song-In - LEE, Won-Ki - KANG, Sang-Soo - LEE, Sue-Young - JEONG, Myeong-Ja - LEE, Hee Jae - KIM, Sung-Soo - JOHNSON, Gall V. W. - CHUN, Wanjoo. Suppression of Autophagy and Activation of Glycogen Synthase Kinase 3beta Facilitate the Aggregate Formation of Tau. In KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY. ISSN 1226-4512, APR 2011, vol. 15, no. 2, p. 107-114. JUNG, Hyun Jung - PARK, Seok Soon - MOK, Ji Oh - LEE, Tae Kyeong - PARK, Choon Sik - PARK, Sun Ah. Increased expression of three-repeat isoforms of tau contributes to tau pathology in a rat model of chronic type 2 diabetes. In EXPERIMENTAL NEUROLOGY. ISSN 0014-4886, APR 2011, vol. 228, no. 2, p. 232-241. YAMAMOTO, Yasuhiro - TAKASE, Kenkichi - KISHINO, Junji - FUJITA, Megumi - OKAMURA, Noboru - SAKAEDA, Toshiyuki - FUJIMOTO, Masafumi - YAGAMI, Tatsurou. Proteomic Identification of Protein Targets for 15-Deoxy-Delta(12,14)-Prostaglandin J(2) in Neuronal Plasma Membrane. In PLOS ONE. ISSN 1932-6203, MAR 18 2011, vol. 6, no. 3. YUZWA, Scott A. - YADAV, Anuj K. - SKOROBOGATKO, Yuliya - CLARK, Thomas - VOSSELLER, Keith - VOCADLO, David J. Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody. In AMINO ACIDS. ISSN 0939-4451, MAR 2011, vol. 40, no. 3, p. 857-868. CHANG, Edward - KIM, Sohee - SCHAFER, Kelsey N. - KURET, Jeff. Pseudophosphorylation of tau protein directly modulates its aggregation kinetics. In BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. ISSN 1570-9639, FEB 2011, vol. 1814, no. 2, p. 388-395. WHITTINGTON, Robert A. - VIRAG, Laszlo - MARCOUILLER, Francois - PAPON, Marie-Amelie - EL KHOURY, Noura B. - JULIEN, Carl - MORIN, Francoise - EMALA, Charles W. - PLANEL, Emmanuel. Propofol Directly Increases Tau Phosphorylation. In PLOS ONE. ISSN 1932-6203, JAN 31 2011, vol. 6, no. 1. SCALES, Timothy M. E. - DERKINDEREN, Pascal - LEUNG, Kit-Yi - BYERS, Helen L. - WARD, Malcolm A. - PRICE, Caroline - BIRD, Ian N. - PERERA, Timothy - KELLIE, Stuart - WILLIAMSON, Ritchie - ANDERTON, Brian H. - REYNOLDS, C. Hugh. Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, JAN 26 2011, vol. 6. STIELER, Jens T. - BULLMANN, Torsten - KOHL, Franziska - TOIEN, Oivind - BRUECKNER, Martina K. - HAERTIG, Wolfgang - BARNES, Brian M. - ARENDT, Thomas. The Physiological Link between Metabolic Rate Depression and Tau Phosphorylation in Mammalian Hibernation. In PLOS ONE. ISSN 1932-6203, JAN 18 2011, vol. 6, no. 1. MONDRAGON-RODRIGUEZ, Siddhartha - GARCIA-SIERRA, Francisco - CASADESUS, Gemma - LEE, Hyoung-gon - PETERSEN, Robert B. - PERRY, George - ZHU, Xiongwei - SMITH, Mark A. Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities. In NEUROCHEMICAL MECHANISMS IN DISEASE. ISSN 2190-5215, 2011, vol. 1, p. 607-631. CORBO, Christopher P. - ALONSO, Alejandra del C. Therapeutic Targets in Alzheimer's Disease and Related Tauopathies. In BRAIN AS A DRUG TARGET. ISSN 1877-1173, 2011, vol. 98, p. 47-83. MEDEIROS, Rodrigo - BAGLIETTO-VARGAS, David - LAFERLA, Frank M. The Role of Tau in Alzheimer's Disease and Related Disorders. In CNS NEUROSCIENCE & THERAPEUTICS. ISSN 1755-5930, 2011, vol. 17, no. 5, p. 514-524. MAETZLER, Walter - STAPF, Anne Kathrin - SCHULTE, Claudia - HAUSER, Ann-Kathrin - LERCHE, Stefanie - WURSTER, Isabel - SCHLEICHER, Erwin - MELMS, Arthur - BERG, Daniela. Serum and Cerebrospinal Fluid Uric Acid Levels in Lewy Body Disorders: Associations with Disease Occurrence and Amyloid-beta Pathway. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2011, vol. 27, no. 1, p. 119-126. LEE, Sangmook - HALL, Garth F. - SHEA, Thomas B. Potentiation of Tau Aggregation by cdk5 and GSK3 beta. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2011, vol. 26, no. 2, p. 355-364. NOVAK, Petr - PRCINA, Michal - KONTSEKOVA, Eva. Tauons and Prions: Infamous Cousins?. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2011, vol. 26, no. 3, p. 413-430. DRAGICEVIC, Natasa - SMITH, Adam - LIN, Xiaoyang - YUAN, Fang - COPES, Neil - DELIC, Vedad - TAN, Jun - CAO, Chuanhai - SHYTLE, R. Douglas - BRADSHAW, Patrick C. Green Tea Epigallocatechin-3-Gallate (EGCG) and Other Flavonoids Reduce Alzheimer's Amyloid-Induced Mitochondrial Dysfunction. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2011, vol. 26, no. 3, p. 507-521. SALMINEN, Antero - OJALA, Johanna - KAARNIRANTA, Kai - HILTUNEN, Mikko - SOININEN, Hilkka. Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, JAN 2011, vol. 93, no. 1, p. 99-110. YAN, Xiao-Xin - CAI, Yan - SHELTON, Jarod - DENG, Si-Hao - LUO, Xue-Gang - ODDO, Salvatore - LAFERLA, Frank M. - CAI, Huaibin - ROSE, Gregory M. - PATRYLO, Peter R. Chronic Temporal Lobe Epilepsy Is Associated with Enhanced Alzheimer-Like Neuropathology in 36 x Tg-AD Mice. In PLOS ONE. ISSN 1932-6203, NOV 14 2012, vol. 7, no. 11. CARDENAS, Ana M. - ARDILES, Alvaro O. - BARRAZA, Natalia - BAEZ-MATUS, Ximena - CAVIEDES, Pablo. Role of Tau Protein in Neuronal Damage in Alzheimer's Disease and Down Syndrome. In ARCHIVES OF MEDICAL RESEARCH. ISSN 0188-4409, NOV 2012, vol. 43, no. 8, SI, p. 645-654. BRAITHWAITE, Steven P. - VORONKOV, Michael - STOCK, Jeffry B. - MOURADIAN, M. Maral. Targeting phosphatases as the next generation of disease modifying therapeutics for Parkinson's disease. In NEUROCHEMISTRY INTERNATIONAL. ISSN 0197-0186, NOV 2012, vol. 61, no. 6, p. 899-906. DAI, Minxian - FREEMAN, Brandi - SHIKANI, Henry J. - BRUNO, Fernando Pereira - ELIAS COLLADO, J. - MACIAS, Rolando - REZNIK, Sandra E. - DAVIES, Peter - SPRAY, David Conover - TANOWITZ, Herbert Bernard - WEISS, Louis Martin - DESRUISSEAUX, Mahalia Sabrina. Altered Regulation of Akt Signaling with Murine Cerebral Malaria, Effects on Long-Term Neuro-Cognitive Function, Restoration with Lithium Treatment. In PLOS ONE. ISSN 1932-6203, OCT 17 2012, vol. 7, no. 10. HIMMELSTEIN, Diana S. - WARD, Sarah M. - LANCIA, Jody K. - PATTERSON, Kristina R. - BINDER, Lester I. Tau as a therapeutic target in neurodegenerative disease. In PHARMACOLOGY & THERAPEUTICS. ISSN 0163-7258, OCT 2012, vol. 136, no. 1, p. 8-22. NGO, Son Tung - LI, Mai Suan. Curcumin Binds to A beta(1-40) Peptides and Fibrils Stronger Than Ibuprofen and Naproxen. In JOURNAL OF PHYSICAL CHEMISTRY B. ISSN 1520-6106, AUG 30 2012, vol. 116, no. 34, p. 10165-10175. COWAN, Catherine M. - QURAISHE, Shmma - MUDHER, Amritpal. What is the pathological significance of tau oligomers?. In BIOCHEMICAL SOCIETY TRANSACTIONS. ISSN 0300-5127, AUG 2012, vol. 40, 4, p. 693-697. BRETTEVILLE, Alexis - MARCOUILLER, Francois - JULIEN, Carl - EL KHOURY, Noura B. - PETRY, Franck R. - POITRAS, Isabelle - MOUGINOT, Didier - LEVESQUE, Georges - HEBERT, Sebastien S. - PLANEL, Emmanuel. Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors. In SCIENTIFIC REPORTS. ISSN 2045-2322, JUN 29 2012, vol. 2. RIBARIC, Samo. The Pharmacological Properties and Therapeutic Use of Apomorphine. In MOLECULES. ISSN 1420-3049, MAY 2012, vol. 17, no. 5, p. 5289-5309. JAEGER, Laura B. - NATH, Avindra. Modeling HIV-associated neurocognitive disorders in mice: new approaches in the changing face of HIV neuropathogenesis. In DISEASE MODELS & MECHANISMS. ISSN 1754-8403, MAY 2012, vol. 5, no. 3, p. 313-322. DAVE, Kunjan R. - CHRISTIAN, Sherri L. - PEREZ-PINZON, Miguel A. - DREW, Kelly L. Neuroprotection: Lessons from hibernators. In COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY. ISSN 1096-4959, MAY 2012, vol. 162, no. 1-3, p. 1-9. SHIMADA, Kohei - MOTOI, Yumiko - ISHIGURO, Koichi - KAMBE, Taiki - MATSUMOTO, Shin-ei - ITAYA, Masako - KUNICHIKA, Miyuki - MORI, Hideo - SHINOHARA, Atsuko - CHIBA, Momoko - MIZUNO, Yoshikuni - UENO, Takashi - HATTORI, Nobutaka. Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, APR 2012, vol. 46, no. 1, p. 101-108. YUZWA, Scott A. - SHAN, Xiaoyang - MACAULEY, Matthew S. - CLARK, Thomas - SKOROBOGATKO, Yuliya - VOSSELLER, Keith - VOCADLO, David J. Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. In NATURE CHEMICAL BIOLOGY. ISSN 1552-4450, APR 2012, vol. 8, no. 4, p. 393-399. MORE, Swati S. - VINCE, Robert. Potential of a gamma-Glutamyl-Transpeptidase-Stable Glutathione Analogue against Amyloid-beta Toxicity. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, MAR 2012, vol. 3, no. 3, p. 204-210. OREJANA, Lourdes - BARROS-MINONES, Lucia - JORDAN, Joaquin - PUERTA, Elena - AGUIRRE, Norberto. Sildenafil ameliorates cognitive deficits and tau pathology in a senescence-accelerated mouse model. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, MAR 2012, vol. 33, no. 3. BRONCEL, Malgorzata - KRAUSE, Eberhard - SCHWARZER, Dirk - HACKENBERGER, Christian P. R. The Alzheimer's Disease Related Tau Protein as a New Target for Chemical Protein Engineering. In CHEMISTRY-A EUROPEAN JOURNAL. ISSN 0947-6539, FEB 2012, vol. 18, no. 9, p. 2488-2492. CHEN, Qian - ZHOU, Zhou - ZHANG, Lei - WANG, Yuan - ZHANG, Yan-wen - ZHONG, Min - XU, Shang-cheng - CHEN, Chun-hai - LI, Li - YU, Zheng-ping. Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF. In NEUROCHEMISTRY INTERNATIONAL. ISSN 0197-0186, FEB 2012, vol. 60, no. 3, p. 233-242. LI, Lin - ZHANG, Zhi-Feng - HOLSCHER, Christian - GAO, Chong - JIANG, Yuan-Hong - LIU, Yue-Ze. (Val(8)) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains. In EUROPEAN JOURNAL OF PHARMACOLOGY. ISSN 0014-2999, JAN 15 2012, vol. 674, no. 2-3, p. 280-286. JULIEN, Carl - BRETTEVILLE, Alexis - PLANEL, Emmanuel. Biochemical Isolation of Insoluble Tau in Transgenic Mouse Models of Tauopathies. In AMYLOID PROTEINS: METHODS AND PROTOCOLS, SECOND EDITION. ISSN 1064-3745, 2012, vol. 849, p. 473-491. MARTIC, Sanela - BEHESHTI, Samaneh - RAINS, Meghan K. - KRAATZ, Heinz-Bernhard. Electrochemical investigations into Tau protein phosphorylations. In ANALYST. ISSN 0003-2654, 2012, vol. 137, no. 9, p. 2042-2046. NEILL, David. Should Alzheimer's disease be equated with human brain ageing?: A maladaptive interaction between brain evolution and senescence. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, JAN 2012, vol. 11, no. 1, p. 104-122. THOMAS, Stefani N. - FUNK, Kristen E. - WAN, Yunhu - LIAO, Zhongping - DAVIES, Peter - KURET, Jeff - YANG, Austin J. Dual modification of Alzheimer's disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach. In ACTA NEUROPATHOLOGICA. ISSN 0001-6322, JAN 2012, vol. 123, no. 1, p. 105-117. WHITTINGTON, Robert A. - BRETTEVILLE, Alexis - DICKLER, Maya F. - PLANEL, Emmanuel. Anesthesia and tau pathology. In PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. ISSN 0278-5846, DEC 2 2013, vol. 47, p. 147-155. KOSARAJU, Jayasankar - MURTHY, Vishakantha - KHATWAL, Rizwan Basha - DUBALA, Anil - CHINNI, Santhivardhan - NATARAJ, Satish Kumar Muthureddy - BASAVAN, Duraiswamy. Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease. In JOURNAL OF PHARMACY AND PHARMACOLOGY. ISSN 0022-3573, DEC 2013, vol. 65, no. 12, SI, p. 1773-1784. GIACOBINI, Ezio - GOLD, Gabriel. Alzheimer disease therapy-moving from amyloid-beta to tau. In NATURE REVIEWS NEUROLOGY. ISSN 1759-4758, DEC 2013, vol. 9, no. 12, p. 677-686. JEMBREK, Maja Jazvinscak - BABIC, Mirjana - PIVAC, Nela - HOF, Patrick R. - SIMIC, Goran. HYPERPHOSPHORYLATION OF TAU BY GSK-3 beta IN ALZHEIMER'S DISEASE: THE INTERACTION OF A beta AND SPHINGOLIPID MEDIATORS AS A THERAPEUTIC TARGET. In TRANSLATIONAL NEUROSCIENCE. ISSN 2081-3856, DEC 2013, vol. 4, no. 4, p. 466-476. PRUESSING, Katja - VOIGT, Aaron - SCHULZ, Joerg B. Drosophila melanogaster as a model organism for Alzheimer's disease. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, NOV 22 2013, vol. 8. VIET, Man Hoang - CHEN, Chun-Yu - HU, Chin-Kun - CHEN, Yun-Ru - LI, Mai Suan. Discovery of Dihydrochalcone as Potential Lead for Alzheimer's Disease: In Silico and In Vitro Study. In PLOS ONE. ISSN 1932-6203, NOV 18 2013, vol. 8, no. 11. MAN HOANG VIET - NGUYEN, Phuong H. - SON TUNG NGO - LI, Mai Suan - DERREUMAUX, Philippe. Effect of the Tottori Familial Disease Mutation (D7N) on the Monomers and Dimers of A beta(40) and A beta(42). In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, NOV 2013, vol. 4, no. 11, p. 1446-1457. RESETCA, Diana - WILSON, Derek J. Characterizing rapid, activity-linked conformational transitions in proteins via sub-second hydrogen deuterium exchange mass spectrometry. In FEBS JOURNAL. ISSN 1742-464X, NOV 2013, vol. 280, no. 22, p. 5616-5625. XIAO, Haibing - RUN, Xiaoqin - CAO, Xu - SU, Ying - SUN, Zhou - TIAN, Cheng - SUN, Shenggang - LIANG, Zhihou. Temperature control can abolish anesthesia-induced tau hyperphosphorylation and partly reverse anesthesia-induced cognitive impairment in old mice. In PSYCHIATRY AND CLINICAL NEUROSCIENCES. ISSN 1323-1316, NOV 2013, vol. 67, no. 7, p. 493-500. MOROZOVA, Olga A. - MARCH, Zachary M. - ROBINSON, Anne S. - COLBY, David W. Conformational Features of Tau Fibrils from Alzheimer's Disease Brain Are Faithfully Propagated by Unmodified Recombinant Protein. In BIOCHEMISTRY. ISSN 0006-2960, OCT 8 2013, vol. 52, no. 40, p. 6960-6967. DE SILVA, Dilani D. - RAPIOR, Sylvie - SUDARMAN, Enge - STADLER, Marc - XU, Jianchu - ALIAS, S. Aisyah - HYDE, Kevin D. Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry. In FUNGAL DIVERSITY. ISSN 1560-2745, SEP 2013, vol. 62, no. 1, p. 1-40. KOSARAJU, Jayasankar - GALI, Chaitanya Chakravarthi - KHATWAL, Rizwan Basha - DUBALA, Anil - CHINNI, Santhivardhan - HOLSINGER, R. M. Damian - MADHUNAPANTULA, V. Subba Rao - NATARAJ, Satish Kumar Muthureddy - BASAVAN, Duraiswamy. Saxagliptin: A dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease. In NEUROPHARMACOLOGY. ISSN 0028-3908, SEP 2013, vol. 72, p. 291-300. PLATT, Thomas L. - REEVES, Valerie L. - MURPHY, M. Paul. Transgenic models of Alzheimer's disease: Better utilization of existing models through viral transgenesis. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, SEP 2013, vol. 1832, no. 9, SI, p. 1437-1448. WU, Jing - NIE, Sheng-dan - WANG, Shan. Tau pathology in diabetes mellitus. In PHARMAZIE. ISSN 0031-7144, AUG 2013, vol. 68, no. 8, p. 649-652. LEE, Wing-Hin - LOO, Ching-Yee - BEBAWY, Mary - LUK, Frederick - MASON, Rebecca S. - ROHANIZADEH, Ramin. Curcumin and its Derivatives: Their Application in Neuropharmacology and Neuroscience in the 21st Century. In CURRENT NEUROPHARMACOLOGY. ISSN 1570-159X, JUL 2013, vol. 11, no. 4, p. 338-378. ROHN, Troy T. Proteolytic Cleavage of Apolipoprotein E4 as the Keystone for the Heightened Risk Associated with Alzheimer's Disease. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, JUL 2013, vol. 14, no. 7, p. 14908-14922. YOSHIYAMA, Yasumasa - LEE, Virginia M. Y. - TROJANOWSKI, John Q. Therapeutic strategies for tau mediated neurodegeneration. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. ISSN 0022-3050, JUL 2013, vol. 84, no. 7, p. 784-795. NIJHOLT, Diana A. T. - NOLLE, Anna - VAN HAASTERT, Elise S. - EDELIJN, Hessel - TOONEN, Ruud F. - HOOZEMANS, Jeroen J. M. - SCHEPER, Wiep. Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, JUL 2013, vol. 34, no. 7, p. 1759-1771. MERINO-SERRAIS, Paula - BENAVIDES-PICCIONE, Ruth - BLAZQUEZ-LLORCA, Lidia - KASTANAUSKAITE, Asta - RABANO, Alberto - AVILA, Jesus - DEFELIPE, Javier. The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer's disease. In BRAIN. ISSN 0006-8950, JUN 2013, vol. 136, 6, p. 1913-1928. BHATIA, Neha - HALL, Garth F. Untangling the role of tau in Alzheimer's disease: A unifying hypothesis. In TRANSLATIONAL NEUROSCIENCE. ISSN 2081-3856, JUN 2013, vol. 4, no. 2, p. 115-133. LEE, Sanghyun - LIU, Yuzhong - LIM, Mi Hee. Untangling Amyloid-beta, Tau, and Metals in Alzheimer's Disease. In ACS CHEMICAL BIOLOGY. ISSN 1554-8929, MAY 2013, vol. 8, no. 5, p. 856-865. MERTENS, Jerome - STUEBER, Kathrin - POPPE, Daniel - DOERR, Jonas - LADEWIG, Julia - BRUESTLE, Oliver - KOCH, Philipp. Embryonic Stem Cell-Based Modeling of Tau Pathology in Human Neurons. In AMERICAN JOURNAL OF PATHOLOGY. ISSN 0002-9440, MAY 2013, vol. 182, no. 5, p. 1769-1779. LALLA, Rakhee - GONMEZ, Gizem. The role of sirtuins in Alzheimer's disease. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, APR 9 2013, vol. 5. NORRIS, Vic - AMAR, Patrick - LEGENT, Guillaume - RIPOLL, Camille - THELLIER, Michel - OVADI, Judit. Sensor potency of the moonlighting enzyme-decorated cytoskeleton: the cytoskeleton as a metabolic sensor. In BMC BIOCHEMISTRY. ISSN 1471-2091, FEB 11 2013, vol. 14. PAPON, Marie-Amelie - EL LIHOURY, Noura B. - MARCOUILLER, Francois - JULIEN, Carl - MORIN, Francoise - BRETTEVILLE, Alexis - PETRY, Franck R. - GAUDREAU, Simon - AMRANI, Abdelaziz - MATHEWS, Paul M. - HEBERT, Sebastien S. - PLANEL, Emmanuel. Deregulation of Protein Phosphatase 2A and Hyperphosphorylation of tau Protein Following Onset of Diabetes in NOD Mice. In DIABETES. ISSN 0012-1797, FEB 2013, vol. 62, no. 2, p. 609-617. ZENG, Bai-Yun - SALVAGE, Sarah - JENNER, Peter. Effect and Mechanism of Acupuncture on Alzheimer's Disease. In NEUROBIOLOGY OF ACUPUNCTURE. ISSN 0074-7742, 2013, vol. 111, p. 181-195. LU, Yang - HE, Hai-Jin - ZHOU, Jun - MIAO, Jun-Ye - LU, Jing - HE, Ying-Ge - PAN, Rong - WEI, Yan - LIU, Ying - HE, Rong-Qiao. Hyperphosphorylation Results in Tau Dysfunction in DNA Folding and Protection. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 37, no. 3, p. 551-563. HUBER, Bertrand R. - MEABON, James S. - MARTIN, Tobin J. - MOURAD, Pierre D. - BENNETT, Raymond - KRAEMER, Brian C. - CERNAK, Ibolja - PETRIE, Eric C. - EMERY, Michael J. - SWENSON, Erik R. - MAYER, Cynthia - MEHIC, Edin - PESKIND, Elaine R. - COOK, David G. Blast Exposure Causes Early and Persistent Aberrant Phospho- and Cleaved-Tau Expression in a Murine Model of Mild Blast-Induced Traumatic Brain Injury. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 37, no. 2, p. 309-323. GRIMM, Marcus O. W. - ZIMMER, Valerie C. - LEHMANN, Johannes - GRIMM, Heike S. - HARTMANN, Tobias. The Impact of Cholesterol, DHA, and Sphingolipids on Alzheimer's Disease. In BIOMED RESEARCH INTERNATIONAL. ISSN 2314-6133, 2013. MADESWARAN, Arumugam - UMAMAHESWARI, Muthuswamy - ASOKKUMAR, Kuppusamy - SIVASHANMUGAM, Thirumalaisamy - SUBHADRADEVI, Varadharajan - JAGANNATH, Puliyath. Computational drug discovery of potential TAU protein kinase I inhibitors using in silico docking studies. In BANGLADESH JOURNAL OF PHARMACOLOGY. ISSN 1991-007X, 2013, vol. 8, no. 2, p. 131-135. JIANG, Xia - JIA, Lin-Wei - LI, Xiao-Hong - CHENG, Xiang-Shu - XIE, Jia-Zhao - MA, Zhi-Wei - XU, Wei-Jie - LIU, Yue - YAO, Yun - DU, Lai-Ling - ZHOU, Xin-Wen. Capsaicin Ameliorates Stress-Induced Alzheimer's Disease-Like Pathological and Cognitive Impairments in Rats. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 35, no. 1, p. 91-105. ROHN, Troy T. The Triggering Receptor Expressed on Myeloid Cells 2: "TREM-ming'' the Inflammatory Component Associated with Alzheimer's Disease. In OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. ISSN 1942-0900, 2013. CHEN, Shun - GE, Xuemei - CHEN, Yinghui - LV, Nan - LIU, Zhenguo - YUAN, Weien. Advances with RNA interference in Alzheimer's disease research. In DRUG DESIGN DEVELOPMENT AND THERAPY. ISSN 1177-8881, 2013, vol. 7, p. 117-125. MINJAREZ, Benito - VALERO RUSTARAZO, Ma. Luz - SANCHEZ DEL PINO, Manuel M. - GONZALEZ-ROBLES, Arturo - SOSA-MELGAREJO, Jorge A. - LUNA-MUNOZ, Jose - MENA, Raul - PEDRO LUNA-ARIAS, Juan. Identification of Polypeptides in Neurofibrillary Tangles and Total Homogenates of Brains with Alzheimer's Disease by Tandem Mass Spectrometry. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 34, no. 1, p. 239-262. SINADINOS, Christopher - QURAISHE, Shmma - SEALEY, Megan - SAMSON, P. Benjamin - MUDHER, Amrit - WYTTENBACH, Andreas. Low Endogenous and Chemical Induced Heat Shock Protein Induction in a 0N3Rtau-Expressing Drosophila Larval Model of Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 33, no. 4, p. 1117-1133. SAHARA, Naruhiko - DETURE, Michael - REN, Yan - EBRAHIM, Abdul-Shukkur - KANG, Dongcheul - KNIGHT, Joshua - VOLBRACHT, Christiane - PEDERSEN, Jan Torleif - DICKSON, Dennis W. - YEN, Shu-Hui - LEWIS, Jada. Characteristics of TBS-Extractable Hyperphosphorylated Tau Species: Aggregation Intermediates in rTg4510 Mouse Brain. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 33, no. 1, p. 249-263. ZHU, Yanping - SHAN, Xiaoyang - YUZWA, Scott A. - VOCADLO, David J. The Emerging Link between O-GlcNAc and Alzheimer Disease. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, DEC 12 2014, vol. 289, no. 50, p. 34472-34481. TEPPER, Katharina - BIERNAT, Jacek - KUMAR, Satish - WEGMANN, Susanne - TIMM, Thomas - HUEBSCHMANN, Sabrina - REDECKE, Lars - MANDELKOW, Eva-Maria - MUELLER, Daniel J. - MANDELKOW, Eckhard. Oligomer Formation of Tau Protein Hyperphosphorylated in Cells. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, DEC 5 2014, vol. 289, no. 49, p. 34389-34407. KAMAT, Pradip K. - RAI, Shivika - SWARNKAR, Supriya - SHUKLA, Rakesh - NATH, Chandishwar. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, DEC 2014, vol. 50, no. 3, p. 852-865. ZHANG, Zhentao - SONG, Mingke - LIU, Xia - KANG, Seong Su - KWON, Ti-Sun - DUONG, Duc M. - SEYFRIED, Nicholas T. - HU, William T. - LIU, Zhixue - WANG, Jian-Zhi - CHENG, Liming - SUN, Yi E. - YU, Shan Ping - LEVEY, Allan I. - YE, Keqiang. Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease. In NATURE MEDICINE. ISSN 1078-8956, NOV 2014, vol. 20, no. 11, p. 1254-1262. CRESCENZI, Rachelle - DEBROSSE, Catherine - NANGA, Ravi Prakash Reddy - REDDY, Sanjana - HARIS, Mohammed - HARIHARAN, Hari - IBA, Michiyo - LEE, Virginia M. Y. - DETRE, John A. - BORTHAKUR, Arijitt - REDDY, Ravinder. In vivo measurement of glutamate loss is associated with synapse loss in a mouse model of tauopathy. In NEUROIMAGE. ISSN 1053-8119, NOV 1 2014, vol. 101, p. 185-192. SIGALA, Julien - JUMEAU, Fanny - CAILLET-BOUDIN, Marie-Laure - SERGEANT, Nicolas - BALLOT, Caroline - RIGOT, Jean-Marc - MARCELLI, Francois - TARDIVEL, Meryem - BUEE, Luc - MITCHELL, Valerie. Immunodetection of Tau microtubule-associated protein in human sperm and testis. In ASIAN JOURNAL OF ANDROLOGY. ISSN 1008-682X, NOV-DEC 2014, vol. 16, no. 6, p. 927-928. YUZWA, Scott A. - SHAN, Xiaoyang - JONES, Bryan A. - ZHAO, Gang - WOODWARD, Melissa L. - LI, Xiaojing - ZHU, Yanping - MCEACHERN, Ernest J. - SILVERMAN, Michael A. - WATSON, Neil V. - GONG, Cheng-Xin - VOCADLO, David J. Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, OCT 26 2014, vol. 9. ALEXANDER, Adanna G. - MARFIL, Vanessa - LI, Chris. Use of Caenorhabditis elegans as a model to study Alzheimer's disease and other neurodegenerative diseases. In Frontiers in Genetics. ISSN 1664-8021, SEP 5 2014, vol. 5, p. 279-Article No.: 279. DROPPELMANN, Cristian A. - CAMPOS-MELO, Danae - ISHTIAQ, Muhammad - VOLKENING, Kathryn - STRONG, Michael J. RNA metabolism in ALS: When normal processes become pathological. In AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION. ISSN 2167-8421, SEP 2014, vol. 15, no. 5-6, p. 321-336. CAMERO, Sergio - BENITEZ, Maria J. - CUADROS, Raquel - HERNANDEZ, Felix - AVILA, Jesus - JIMENEZ, Juan S. Thermodynamics of the Interaction between Alzheimer's Disease Related Tau Protein and DNA. In PLOS ONE. ISSN 1932-6203, AUG 15 2014, vol. 9, no. 8. PHAN MINH TRUONG - MAN HOANG VIET - NGUYEN, Phuong H. - HU, Chin-Kun - LI, Mai Suan. Effect of Taiwan Mutation (D7H) on Structures of Amyloid-beta Peptides: Replica Exchange Molecular Dynamics Study. In JOURNAL OF PHYSICAL CHEMISTRY B. ISSN 1520-6106, JUL 31 2014, vol. 118, no. 30, p. 8972-8981. LEE, Jaewon - JO, Dong-Gyu - PARK, Daeui - CHUNG, Hae Young - MATTSON, Mark P. Adaptive Cellular Stress Pathways as Therapeutic Targets of Dietary Phytochemicals: Focus on the Nervous System. In PHARMACOLOGICAL REVIEWS. ISSN 0031-6997, JUL 2014, vol. 66, no. 3, p. 815-868. SPEARS, William - FURGERSON, Matthew - SWEETNAM, John Michael - EVANS, Parker - GEARING, Marla - FECHHEIMER, Marcus - FURUKAWA, Ruth. Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain. In BMC NEUROSCIENCE. ISSN 1471-2202, JUN 14 2014, vol. 15. MOTOI, Yumiko - SHIMADA, Kohei - ISHIGURO, Koichi - HATTORI, Nobutaka. Lithium and Autophagy. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, JUN 2014, vol. 5, no. 6, p. 434-442. YUZWA, Scott A. - CHEUNG, Adrienne H. - OKON, Mark - MCINTOSH, Lawrence P. - VOCADLO, David J. O-GIcNAc Modification of tau Directly Inhibits Its Aggregation without Perturbing the Conformational Properties of tau Monomers. In JOURNAL OF MOLECULAR BIOLOGY. ISSN 0022-2836, APR 17 2014, vol. 426, no. 8, p. 1736-1752. GOLBE, Lawrence I. The Tau of PSP: A Long Road to Treatment. In MOVEMENT DISORDERS. ISSN 0885-3185, APR 2014, vol. 29, no. 4, p. 431-434. WANG, Jian-Zhi - WANG, Zhi-Hao - TIAN, Qing. Tau hyperphosphorylation induces apoptotic escape and triggers neurodegeneration in Alzheimer's disease. In NEUROSCIENCE BULLETIN. ISSN 1673-7067, APR 2014, vol. 30, no. 2, SI, p. 359-366. QIAN, Wei - LIU, Fei. Regulation of alternative splicing of tau exon 10. In NEUROSCIENCE BULLETIN. ISSN 1673-7067, APR 2014, vol. 30, no. 2, SI, p. 367-377. MIETELSKA-POROWSKA, Anna - WASIK, Urszula - GORAS, Marcelina - FILIPEK, Anna - NIEWIADOMSKA, Grazyna. Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, MAR 2014, vol. 15, no. 3, p. 4671-4713. VAIDYANATHAN, Krithika - DURNING, Sean - WELLS, Lance. Functional O-GIcNAc modifications: Implications in molecular regulation and pathophysiology. In CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. ISSN 1040-9238, MAR-APR 2014, vol. 49, no. 2, p. 140-163. EL KHOURY, Noura B. - GRATUZE, Maud - PAPON, Marie-Amelie - BRETTEVILLE, Alexis - PLANEL, Emmanuel. Insulin dysfunction and Tau pathology. In FRONTIERS IN CELLULAR NEUROSCIENCE. ISSN 1662-5102, FEB 11 2014, vol. 8. LABBE, Catherine - ROSS, Owen A. Association Studies of Sporadic Parkinson's Disease in the Genomic Era. In CURRENT GENOMICS. ISSN 1389-2029, FEB 2014, vol. 15, no. 1, p. 2-10. CAILLET-BOUDIN, Marie-Laure - FERNANDEZ-GOMEZ, Francisco-Jose - TRAN, Helene - DHAENENS, Claire-Marie - BUEE, Luc - SERGEANT, Nicolas. Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathy. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, JAN 9 2014, vol. 6. AHMED, Aseef H. - SUBAIEA, Gehad M. - EID, Aseel - LI, Liya - SEERAM, Navindra P. - ZAWIA, Nasser H. Pomegranate Extract Modulates Processing of Amyloid-beta Precursor Protein in an Aged Alzheimer's Disease Animal Model. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, 2014, vol. 11, no. 9, p. 834-843. YUZWA, Scott A. - VOCADLO, David J. O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond. In CHEMICAL SOCIETY REVIEWS. ISSN 0306-0012, 2014, vol. 43, no. 19, p. 6839-6858. PHAM DINH QUOC HUY - LI, Mai Suan. Binding of fullerenes to amyloid beta fibrils: size matters. In PHYSICAL CHEMISTRY CHEMICAL PHYSICS. ISSN 1463-9076, 2014, vol. 16, no. 37, p. 20030-20040. RUDRABHATLA, Parvathi. Regulation of Neuronal Cytoskeletal Protein Phosphorylation in Neurodegenerative Diseases. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2014, vol. 41, no. 3, p. 671-684. KHAN, Zafar U. - MARTIN-MONTANEZ, Elisa - NAVARRO-LOBATO, Irene - MULY, E. Chris. Memory Deficits in Aging and Neurological Diseases. In MOLECULAR BASIS OF MEMORY. ISSN 1877-1173, 2014, vol. 122, p. 1-29. OESTERLING, Benjamin M. - GULATI, Anil - JOSHI, Medha D. Nanocarrier-Based Approaches for Treatment and Detection of Alzheimer's Disease. In JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY. ISSN 1533-4880, JAN 2014, vol. 14, no. 1, p. 137-156. XIE, Min - HAN, Yun - YU, Quntao - WANG, Xia - WANG, Shaohui - LIAO, Xiaomei. UCH-L1 Inhibition Decreases the Microtubule-Binding Function of Tau Protein. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2016, vol. 49, no. 2, pp. 353. WANG, Yipeng - MANDELKOW, Eckhard. Tau in physiology and pathology. In NATURE REVIEWS NEUROSCIENCE. ISSN 1471-003X, 2016, vol. 17, no. 1, pp. 5. VANITALLIE, Theodore B. Biomarkers, ketone bodies, and the prevention of Alzheimer's disease. In METABOLISM-CLINICAL AND EXPERIMENTAL. ISSN 0026-0495, 2015, vol. 64, no. 3, pp. S51. SMAOUI, Mohamed R. - WALDISPUEHL, Jerome. Computational re-engineering of Amylin sequence with reduced amyloidogenic potential. In BMC STRUCTURAL BIOLOGY. ISSN 1472-6807, 2015, vol. 15, no., pp. OGAWA, Mitsutaka - SAWAGUCHI, Shogo - KAMEMURA, Kazuo - OKAJIMA, Tetsuya. Intracellular and extracellular O-linked N-acetylglucosamine in the nervous system. In EXPERIMENTAL NEUROLOGY. ISSN 0014-4886, 2015, vol. 274, no., pp. 166. NAINI, Seyedeh Maryam Alavi - SOUSSI-YANICOSTAS, Nadia. Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies? In OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. ISSN 1942-0900, 2015, vol., no., pp. YANG, Cui-cui - KUAI, Xue-xian - GAO, Wen-bin - YU, Jian-chun - WANG, Qi - LI, Lin - ZHANG, Lan. Morroniside-Induced PP2A Activation Antagonizes Tau Hyperphosphorylation in a Cellular Model of Neurodegeneration. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2016, vol. 51, no. 1, pp. 33. FRENKEL-PINTER, Moran - TAL, Sharon - SCHERZER-ATTALI, Roni - ABU-HUSSIEN, Malak - ALYAGOR, Idan - EISENBAUM, Tal - GAZIT, Ehud - SEGAL, Daniel. Naphthoquinone-Tryptophan Hybrid Inhibits Aggregation of the Tau-Derived Peptide PHF6 and Reduces Neurotoxicity. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2016, vol. 51, no. 1, pp. 165. OJO, Joseph O. - MOUZON, Benoit C. - CRAWFORD, Fiona. Repetitive head trauma, chronic traumatic encephalopathy and tau: Challenges in translating from mice to men. In EXPERIMENTAL NEUROLOGY. ISSN 0014-4886, 2016, vol. 275, no., pp. 389. DU, Lai-Ling - CHAI, Da-Min - ZHAO, Li-Na - LI, Xiao-Hong - ZHANG, Fu-Chi - ZHANG, Hai-Bo - LIU, Lv-Bin - WU, Kang - LIU, Rong - WANG, Jian-Zhi - ZHOU, Xin-Wen. AMPK Activation Ameliorates Alzheimer's Disease-Like Pathology and Spatial Memory Impairment in a Streptozotocin-Induced Alzheimer's Disease Model in Rats. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2015, vol. 43, no. 3, pp. 775. DAY, Ryan J. - MASON, Maria J. - THOMAS, Chloe - POON, Wayne W. - ROHN, Troy T. Caspase-Cleaved Tau Co-Localizes with Early Tangle Markers in the Human Vascular Dementia Brain. In PLOS ONE. ISSN 1932-6203, 2015, vol. 10, no. 7, pp. ALBU, Razuan F. - CHAN, Gerard T. - ZHU, Mang - WONG, Eric T. C. - TAGHIZADEH, Farnaz - HU, Xiaoke - MEHRAN, Arya E. - JOHNSON, James D. - GSPONER, Joerg - MAYOR, Thibault. A feature analysis of lower solubility proteins in three eukaryotic systems. In JOURNAL OF PROTEOMICS. ISSN 1874-3919, 2015, vol. 118, no., pp. 21. TIAN, Huilai - DAVIDOWITZ, Eliot - LOPEZ, Patricia - HE, Ping - SCHULZ, Philip - MOE, James - SIERKS, Michael R. Isolation and characterization of antibody fragments selective for toxic oligomeric tau. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, 2015, vol. 36, no. 3, pp. 1342. EL KHOURY, Noura B. - GRATUZE, Maud - PETRY, Franck - PAPON, Marie-Amelie - JULIEN, Carl - MARCOUILLER, Francois - MORIN, Francoise - NICHOLLS, Samantha B. - CALON, Frederic - HEBERT, Sebastien S. - MARETTE, Andre - PLANEL, Emmanuel. Hypothermia mediates age-dependent increase of tau phosphorylation in db/db mice. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, 2016, vol. 88, no., pp. 55. PEREZ-POLO, J. R. - REA, H. C. - JOHNSON, K. M. - PARSLEY, M. A. - UNABIA, G. C. - XU, G.Y. - PROUGH, D. - DEWITT, D. S. - SPRATT, H. - HULSEBOSCH, C. E. A Rodent Model of Mild Traumatic Brain Blast Injury. In JOURNAL OF NEUROSCIENCE RESEARCH. ISSN 0360-4012, 2015, vol. 93, no. 4, pp. 549. MITRA, Gopa - GUPTA, Suvroma - PODDAR, Asim - BHATTACHARYYA, Bhabatarak. MAP2c prevents arachidonic acid-induced fibril formation of tau: Role of chaperone activity and phosphorylation. In BIOPHYSICAL CHEMISTRY. ISSN 0301-4622, 2015, vol. 205, no., pp. 16. SCHENGRUND, Cara-Lynne. Gangliosides: glycosphingolipids essential for normal neural development and function. In TRENDS IN BIOCHEMICAL SCIENCES. ISSN 0968-0004, 2015, vol. 40, no. 7, pp. 397. WON, Je-Seong - ANNAMALAI, Balasubramaniam - CHOI, Seungho - SINGH, Inderjit - SINGH, Autar K. S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion. In BRAIN RESEARCH. ISSN 0006-8993, 2015, vol. 1624, no., pp. 359. MAKANI, Vishruti - JANG, Yong-gil - CHRISTOPHER, Kevin - JUDY, Wesley - ECKSTEIN, Jacob - HENSLEY, Kenneth - CHIAIA, Nicolas - KIM, Dong-Shik - PARK, Joshua. BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR. In PLOS ONE. ISSN 1932-6203, 2016, vol. 11, no. 3, pp. MEHTA, Dharmini C. - SHORT, Jennifer L. - HILMER, Sarah N. - NICOLAZZO, Joseph A. Drug Access to the Central Nervous System in Alzheimer's Disease: Preclinical and Clinical Insights. In PHARMACEUTICAL RESEARCH. ISSN 0724-8741, 2015, vol. 32, no. 3, pp. 819. FLORES-RODRIGUEZ, Paola - ONTIVEROS-TORRES, Miguel A. - CARDENAS-AGUAYO, Maria C. - LUNA-ARIAS, Juan P. - MERAZ-RIOS, Marco A. - VIRAMONTES-PINTOS, Amparo - HARRINGTON, Charles R. - WISCHIK, Claude M. - MENA, Raul - FLORAN-GARDUNO, Benjamin - LUNA-MUNOZ, Jose. The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease. In FRONTIERS IN NEUROSCIENCE. ISSN 1662-453X, 2015, vol. 9, no., pp. VERHEYEN, An - DIELS, Annick - DIJKMANS, Joyce - OYELAMI, Tutu - MENEGHELLO, Giulia - MERTENS, Liesbeth - VERSWEYVELD, Sofie - BORGERS, Marianne - BUIST, Arjan - PEETERS, Pieter - CIK, Miroslav. Using Human iPSC-Derived Neurons to Model TAU Aggregation. In PLOS ONE. ISSN 1932-6203, 2015, vol. 10, no. 12, pp. GRUENINGER, F. Drug development for tauopathies. In NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. ISSN 0305-1846, 2015, vol. 41, no. 1, pp. 81. REIMAND, Jueri - WAGIH, Omar - BADER, Gary D. Evolutionary Constraint and Disease Associations of Post-Translational Modification Sites in Human Genomes. In PLOS GENETICS. ISSN 1553-7390, 2015, vol. 11, no. 1, pp. MUSHTAQ, Gohar - GREIG, Nigel H. - ANWAR, Firoz - AL-ABBASI, Fahad A. - ZAMZAMI, Mazin A. - AL-TALHI, Hasan A. - KAMAL, Mohammad A. Neuroprotective Mechanisms Mediated by CDK5 Inhibition. In CURRENT PHARMACEUTICAL DESIGN. ISSN 1381-6128, 2016, vol. 22, no. 5, pp. 527. BOOPATHI, Subramaniam - KOLANDAIVEL, Ponmalai. Study on the inter- and intra-peptide salt-bridge mechanism of A beta(23-28) oligomer interaction with small molecules: QM/MM method. In MOLECULAR BIOSYSTEMS. ISSN 1742-206X, 2015, vol. 11, no. 7, pp. 2031. SHIGEMITSU, Yoshiki - IWAYA, Naoko - GODA, Natsuko - MATSUZAKI, Mizuki - TENNO, Takeshi - NARITA, Akihiro - HOSHI, Minako - HIROAKI, Hidekazu. Nuclear magnetic resonance evidence for the dimer formation of beta amyloid peptide 1-42 in 1,1,1,3,3,3-hexafluoro-2-propanol. In ANALYTICAL BIOCHEMISTRY. ISSN 0003-2697, 2016, vol. 498, no., pp. 59. ZHU, Shaolong - SHALA, Agnesa - BEZGINOV, Alexandr - SLJOKA, Adnan - AUDETTE, Gerald - WILSON, Derek J. Hyperphosphorylation of Intrinsically Disordered Tau Protein Induces an Amyloidogenic Shift in Its Conformational Ensemble. In PLOS ONE. ISSN 1932-6203, 2015, vol. 10, no. 3, pp. MAN HOANG VIET - SIPOSOVA, Katarina - BEDNARIKOVA, Zuzana - ANTOSOVA, Andrea - TRUC TRANG NGUYEN - GAZOVA, Zuzana - LI, Mai Suan. In Silico and in Vitro Study of Binding Affinity of Tripeptides to Amyloid beta Fibrils: Implications for Alzheimer's Disease. In JOURNAL OF PHYSICAL CHEMISTRY B. ISSN 1520-6106, 2015, vol. 119, no. 16, pp. 5145. VERWILST, Peter - SUNWOO, Kyoung - KIM, Jong Seung. The role of copper ions in pathophysiology and fluorescent sensors for the detection thereof. In CHEMICAL COMMUNICATIONS. ISSN 1359-7345, 2015, vol. 51, no. 26, pp. 5556. SUI, Dexin - LIU, Mengyu - KUO, Min-Hao. In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein. In JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. ISSN 1940-087X, 2015, vol., no. 95, pp. MALIA, Thomas J. - TEPLYAKOV, Alexey - ERNST, Robin - WU, Sheng-Jiun - LACY, Eilyn R. - LIU, Xuesong - VANDERMEEREN, Marc - MERCKEN, Marc - LUO, Jinquan - SWEET, Raymond W. - GILLILAND, Gary L. Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8. In PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. ISSN 0887-3585, 2016, vol. 84, no. 4, pp. 427. FONTAINE, Sarah N. - SABBAGH, Jonathan J. - BAKER, Jeremy - MARTINEZ-LICHA, Carlos R. - DARLING, April - DICKEY, Chad A. Cellular factors modulating the mechanism of tau protein aggregation. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, 2015, vol. 72, no. 10, pp. 1863. RUBENSTEIN, Richard - CHANG, Binggong - DAVIES, Peter - WAGNER, Amy K. - ROBERTSON, Claudia S. - WANG, Kevin K. W. A Novel, Ultrasensitive Assay for Tau: Potential for Assessing Traumatic Brain Injury in Tissues and Biofluids. In JOURNAL OF NEUROTRAUMA. ISSN 0897-7151, 2015, vol. 32, no. 5, pp. 342. WALLIN, Anders - BJERKE, Maria. Cerebral small vessel disease: Cerebrospinal fluid aspects. In Cerebral Small Vessel Disease, 2011-01-01, pp. 200-215. CHO, Jung Eun - KIM, Jin Ryoun. Recent approaches targeting beta-amyloid for therapeutic intervention of Alzheimer's disease. In Recent Patents on CNS Drug Discovery. ISSN 15748898, 2011-09-01, 6, 3, pp. 222-233. TAUPIN, Philippe. Oxidative Stress in Adult Neurogenesis and in the Pathogenesis of Alzheimer Disease. In Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling, 2011-11-07, pp. 129-137. LEE, Sangmook - KIM, Wonhee - LI, Zhihan - HALL, Garth F. Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model. In International Journal of Alzheimer's Disease, 2012-02-06, pp. RIBARIC, Samo. The pharmacological properties and therapeutic use of apomorphine. In Molecules, 2012-05-01, 17, 5, pp. 5289-5309. LUNA-MUÑOZ, José - ZAMUDIO, Sergio - DE LA CRUZ, Fidel - MINJAREZ-VEGA, Benito - MENA, Raúl. Protective action of the tau protein in Alzheimer | Acción protectora de la proteína tau en la enfermedad de Alzheimer. In Revista Mexicana de Neurociencia. ISSN 16655044, 2012-05-01, 13, 3, pp. 160-167. IDAN-FELDMAN, Anat - OSTRITSKY, Regina - GOZES, Illana. Tau and caspase 3 as targets for neuroprotection. In International Journal of Alzheimer's Disease, 2012-06-20, pp. KOLAROVA, Michala - GARCÍA-SIERRA, Francisco - BARTOS, Ales - RICNY, Jan - RIPOVA, Daniela. Structure and pathology of tau protein in Alzheimer disease. In International Journal of Alzheimer's Disease, 2012-06-20, pp. STURM, Deborah - JAWAD, Mahdi - ALONSO, Alejandra - CORBO, Chris. A cytoskeleton linearity measure. In Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation, 2012-07-02, pp. 45-48. HALL, Garth F. The biology and pathobiology of tau protein. In Cytoskeleton and Human Disease, 2012-12-01, 9781617797880, pp. 285-313. MERINO-SERRAIS, Paula - BENAVIDES-PICCIONE, Ruth - BLAZQUEZ-LLORCA, Lidia - KASTANAUSKAITE, Asta - RÁBANO, Alberto - AVILA, Jesús - DEFELIPE, Javier. The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer's disease. In Brain. ISSN 00068950, 2013-01-01, 136, 6, pp. 1913-1928. HUDSON, Andrew E. - HEROLD, Karl F. - HEMMINGS, Hugh C. Pharmacology of Inhaled Anesthetics. In Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application, 2013-01-01, pp. 159-179. SAVELIEFF, Masha G. - LEE, Sanghyun - LIU, Yuzhong - LIM, Mi Hee. Untangling amyloid-β, tau, and metals in Alzheimer's disease. In ACS Chemical Biology. ISSN 15548929, 2013-05-17, 8, 5, pp. 856-865. FURUKAWA, Yoshiaki. Polymorphism of Tau Fibrils. In Bio-nanoimaging: Protein Misfolding and Aggregation, 2013-11-01, pp. 213-222. XIAO, Haibing - RUN, Xiaoqin - CAO, Xu - SU, Ying - SUN, Zhou - TIAN, Cheng - SUN, Shenggang - LIANG, Zhihou. Temperature control can abolish anesthesia-induced tau hyperphosphorylation and partly reverse anesthesia-induced cognitive impairment in old mice. In Psychiatry and Clinical Neurosciences. ISSN 13231316, 2013-11-01, 67, 7, pp. 493-500. KACPERSKA, Magdalena Justyna - KSIA̧Z̊EK-WINIAREK, Dominika - JASTRZȨBSKI, Karol - GŁA̧BIŃSKI, Andrzej. The attempts to use stem cells in the therapy of selected disorders of the nervous system | Próby wykorzystania komórek macierzystych w terapii wybranych chorób układu nerwowego. In Aktualnosci Neurologiczne. ISSN 16419227, 2013-12-02, 13, 2, pp. 145-156. TAUPIN, Philippe. Stem cells: Cellular and drug therapies. In Stem Cells: Cellular and Drug Therapies, 2014-01-01, 2, pp. 1-212. MA, Teng - TAN, Meng Shan - YU, Jin Tai - TAN, Lan. Resveratrol as a therapeutic agent for alzheimer's disease. In BioMed Research International. ISSN 23146133, 2014-01-01, 2014, pp. GONG, Zhenwei - TAS, Emir - MUZUMDAR, Radhika. Humanin and age-related diseases: A new link? In Frontiers in Endocrinology, 2014-01-01, 5, dEC, pp. JHA, Santosh Kumar - RAI, Archana - SINGH, Hare Ram. High throughput screening of potential inhibitors of alzheimer’s disease associated tau aggregation protein. In International Journal of Pharmaceutical Research, 2014-01-01, 6, 2, pp. 61-66. YANG, Ran Yao - FANG, Jian Song - ZHOU, Dan - LIU, Ai Lin - DU, Guan Hua. Establishment and application of a high-throughput screening assay for Cdk5/p35 inhibitors. In Chinese Journal of New Drugs. ISSN 10033734, 2014-01-01, 23, 7, pp. 781-786. D’ANGELILLO, Anna - PACELLI, Roberto - MARTINELLI, Rosanna - D’ARRIGO, Paolo - STAIBANO, Stefania - SIVERO, Luigi - BISOGNI, Rita - ROMANO, Simona. A role for proteomics in identifying targets for radiosensitizing strategies in Melanoma: The FKBP51 paradigm. In Journal of Proteomics and Bioinformatics, 2014-01-01, 7, 8, pp. 240-247. GIREUD, Monica - SIRISAENGTAKSIN, Natalie - BEAN, Andrew J. Molecular Mechanisms of Neurological Disease. In From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience: Third Edition, 2014-07-11, pp. 639-661. KANAAN, Nicholas M. - HIMMELSTEIN, Diana S. - WARD, Sarah M. - COMBS, Benjamin - BINDER, Lester I. Tau Protein: Biology and Pathobiology. In Movement Disorders: Genetics and Models: Second Edition, 2014-10-29, pp. 857-874. SENECI, Pierfausto. Molecular Targets in Protein Misfolding and Neurodegenerative Disease. In Molecular Targets in Protein Misfolding and Neurodegenerative Disease, 2014-10-09, pp. 1-295. MA, Qin - RUAN, Ying-ying - XU, Hui - SHI, Xiao-meng - WANG, Zhi-xiang - HU, Yan-li. Safflower yellow reduces lipid peroxidation, neuropathology, tau phosphorylation and ameliorates amyloid beta-induced impairment of learning and memory in rats. In BIOMEDICINE & PHARMACOTHERAPY. ISSN 0753-3322, DEC 2015, vol. 76, p. 153-164. WEI RAN-LEI - SONG CHAO-CHUN - YANG MING-YAO. The Mechanisms of Age-related Alzheimer' s Disease and its Drosophila Model. In Zhongguo Shengwu Huaxue yu Fenzi Shengwu Xuebao. ISSN 1007-7626, SEP 2015, vol. 31, no. 9, p. 914-920. LIM, Siok Lam - RODRIGUEZ-ORTIZ, Carlos J. - KITAZAWA, Masashi. Infection, systemic inflammation, and Alzheimer's disease. In MICROBES AND INFECTION. ISSN 1286-4579, AUG 2015, vol. 17, no. 8, p. 549-556. WHITTINGTON, Robert A. - VIRAG, Laszlo - GRATUZE, Maud - PETRY, Franck R. - NOEL, Anastasia - POITRAS, Isabelle - TRUCHETTI, Geoffrey - MARCOUILLER, Francois - PAPON, Marie-Amelie - EL KHOURY, Noura - WONG, Kevin - BRETTEVILLE, Alexis - MORIN, Francoise - PLANEL, Emmanuel. Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, AUG 2015, vol. 36, no. 8, p. 2414-2428. TANG, Zhi - IOJA, Eniko - BERECZKI, Erika - HULTENBY, Kjell - LI, Chunxia - GUAN, Zhizhong - WINBLAD, Bengt - PEI, Jin-Jing. mTor mediates tau localization and secretion: Implication for Alzheimer's disease. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. ISSN 0167-4889, JUL 2015, vol. 1853, no. 7, p. 1646-1657. SENECI, Pierfausto. Protein Misfolding, Neurodegeneration and Tau The Main Players, or the Usual Suspects?. In MOLECULAR TARGETS IN PROTEIN MISFOLDING AND NEURODEGENERATIVE DISEASE. 2015, p. 1-38. KANAAN, Nicholas M. - HIMMELSTEIN, Diana S. - WARD, Sarah M. - COMBS, Benjamin - BINDER, Lester I. Tau Protein: Biology and Pathobiology. In MOVEMENT DISORDERS: GENETICS AND MODELS, 2ND EDITION. 2015, p. 857-874. SUI, Dexin - XU, Xinjing - YE, Xuemei - LIU, Mengyu - MIANECKI, Maxwell - RATTANASINCHAI, Chotirat - BUEHL, Christopher - DENG, Xiexiong - KUO, Min-Hao. Protein Interaction Module-assisted Function X (PIMAX) Approach to Producing Challenging Proteins Including Hyperphosphorylated Tau and Active CDK5/p25 Kinase Complex. In MOLECULAR & CELLULAR PROTEOMICS. ISSN 1535-9476, JAN 2015, vol. 14, no. 1, p. 251-262. RODRIGUEZ-CALLEJAS, Juan D. - FUCHS, Eberhard - PEREZ-CRUZ, Claudia. Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, DEC 22 2016, vol. 8. JIANG, Tianfang - SUN, Qian - CHEN, Shengdi. Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson's disease and Alzheimer's disease. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, DEC 2016, vol. 147, p. 1-19. SHI, Hu - KANG, Baotao - LEE, Jin Yong. Tautomeric Effect of Histidine on the Monomeric Structure of Amyloid beta-Peptide(1-40). In JOURNAL OF PHYSICAL CHEMISTRY B. ISSN 1520-6106, NOV 10 2016, vol. 120, no. 44, p. 11405-11411. SHU, Shu - ZHU, Houze - TANG, Na - CHEN, Wenting - LI, Xinyan - LI, Hao - PEI, Lei - LIU, Dan - MU, Yangling - TIAN, Qing - ZHU, Ling-Qiang - LU, Youming. Selective Degeneration of Entorhinal-CA1 Synapses in Alzheimer's Disease via Activation of DAPK1. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, OCT 19 2016, vol. 36, no. 42, p. 10843-10852. CORBI, Graziamaria - CONTI, Valeria - DAVINELLI, Sergio - SCAPAGNINI, Giovanni - FILIPPELLI, Amelia - FERRARA, Nicola. Dietary Phytochemicals in Neuroimmunoaging: A New Therapeutic Possibility for Humans?. In FRONTIERS IN PHARMACOLOGY. ISSN 1663-9812, OCT 13 2016, vol. 7. PHAM DINH QUOC HUY - QUAN VAN VUONG - LA PENNA, Giovanni - FALLER, Peter - LI, Mai Suan. Impact of Cu(II) Binding on Structures and Dynamics of A beta(42) Monomer and Dimer: Molecular Dynamics Study. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, OCT 2016, vol. 7, no. 10, p. 1348-1363. MANASSERO, Giusi - GUGLIELMOTTO, Michela - ZAMFIR, Raluca - BORGHI, Roberta - COLOMBO, Laura - SALMONA, Mario - PERRY, George - ODETTI, Patrizio - ARANCIO, Ottavio - TAMAGNO, Elena - TABATON, Massimo. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. In AGING CELL. ISSN 1474-9718, OCT 2016, vol. 15, no. 5, p. 914-923. CORREIA, Sonia C. - PERRY, George - MOREIRA, Paula I. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, OCT 2016, vol. 1862, no. 10, p. 1909-1917. KANNO, Takeshi - TSUCHIYA, Ayako - TANAKA, Akito - NISHIZAKI, Tomoyuki. Combination of PKC epsilon Activation and PTP1B Inhibition Effectively Suppresses A beta-Induced GSK-3 beta Activation and Tau Phosphorylation. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, SEP 2016, vol. 53, no. 7, p. 4787-4797. LI, Tong - PAUDEL, Hemant K. 14-3-3 zeta Mediates Tau Aggregation in Human Neuroblastoma M17 Cells. In PLOS ONE. ISSN 1932-6203, AUG 22 2016, vol. 11, no. 8. FADUS, M. - HARRISON, J. - KOLLI, V. ANTI-TAU THERAPIES FOR ALZHEIMER'S DISEASE. In DRUGS OF THE FUTURE. ISSN 0377-8282, AUG 2016, vol. 41, no. 8, p. 485-495. QI, Liqin - KE, Linfang - LIU, Xiaohong - LIAO, Lianming - KE, Sujie - LIU, Xiaoying - WANG, Yanping - LIN, Xiaowei - ZHOU, Yu - WU, Lijuan - CHEN, Zhou - LIU, Libin. Subcutaneous administration of liraglutide ameliorates learning and memory impairment by modulating tau hyperphosphorylation via the glycogen synthase kinase-3 beta pathway in an amyloid beta protein induced alzheimer disease mouse model. In EUROPEAN JOURNAL OF PHARMACOLOGY. ISSN 0014-2999, JUL 15 2016, vol. 783, p. 23-32. GUERREIRO, Patricia Silva - GERHARDT, Ellen - DA FONSECA, Tomas Lopes - BAEHR, Mathias - OUTEIRO, Tiago Fleming - ECKERMANN, Katrin. LRRK2 Promotes Tau Accumulation, Aggregation and Release. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, JUL 2016, vol. 53, no. 5, p. 3124-3135. ZHU, Xiaoyin - TIAN, Jingwei - SUN, Songmei - DONG, Qiuju - ZHANG, Fangxi - ZHANG, Xiumei. (-)-SCR1693 Protects against Memory Impairment and Hippocampal Damage in a Chronic Cerebral Hypoperfusion Rat Model. In SCIENTIFIC REPORTS. ISSN 2045-2322, JUN 28 2016, vol. 6. POLANCO, Juan Carlos - SCICLUNA, Benjamin James - HILL, Andrew Francis - GOTZ, Jurgen. Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, JUN 10 2016, vol. 291, no. 24, p. 12445-12466. LIPPENS, Guy - LANDRIEU, Isabelle - SMET, Caroline - HUVENT, Isabelle - GANDHI, Neha S. - GIGANT, Benoit - DESPRES, Clement - QI, Haoling - LOPEZ, Juan. NMR Meets Tau: Insights into Its Function and Pathology. In BIOMOLECULES. ISSN 2218-273X, JUN 2016, vol. 6, no. 2. WANG, Hongjie - WANG, Ruizhi - CARRERA, Ivan - XU, Shaohua - LAKSHMANA, Madepalli K. TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits. In ENEURO. ISSN 2373-2822, MAY-JUN 2016, vol. 3, no. 3. QI, Haoling - PRABAKARAN, Sudhakaran - CANTRELLE, Francois-Xavier - CHAMBRAUD, Beatrice - GUNAWARDENA, Jeremy - LIPPENS, Guy - LANDRIEU, Isabelle. Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, APR 1 2016, vol. 291, no. 14, p. 7742-7753. GRATUZE, Maud - CISBANI, Giulia - CICCHETTI, Francesca - PLANEL, Emmanuel. Is Huntington's disease a tauopathy?. In BRAIN. ISSN 0006-8950, APR 2016, vol. 139, 4, p. 1014-1025. MAINA, Mahmoud Bukar - AL-HILALY, Youssra K. - SERPELL, Louise C. Nuclear Tau and Its Potential Role in Alzheimer's Disease. In BIOMOLECULES. ISSN 2218-273X, MAR 2016, vol. 6, no. 1. WINSTON, Charisse N. - NOEL, Anastasia - NEUSTADTL, Aidan - PARSADANIAN, Maia - BARTON, David J. - CHELLAPPA, Deepa - WILKINS, Tiffany E. - ALIKHANI, Andrew D. - ZAPPLE, David N. - VILLAPOL, Sonia - PLANEL, Emmanuel - BURNS, Mark P. Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. In AMERICAN JOURNAL OF PATHOLOGY. ISSN 0002-9440, MAR 2016, vol. 186, no. 3, p. 552-567. THYSIADIS, Savvas - MPOUSIS, Spyros - AVRAMIDIS, Nicolaos - KATSAMAKAS, Sotirios - BALOMENOS, Athanasios - REMELLI, Rosaria - EFTHIMIOPOULOS, Spyros - SARLI, Vasiliki. Discovery of novel phenoxazinone derivatives as DKK1/LRP6 interaction inhibitors: Synthesis, biological evaluation and structure-activity relationships. In BIOORGANIC & MEDICINAL CHEMISTRY. ISSN 0968-0896, MAR 1 2016, vol. 24, no. 5, p. 1014-1022. HOUCK, Alexander L. - HERNANDEZ, Felix - AVILA, Jesus. A Simple Model to Study Tau Pathology. In JOURNAL OF EXPERIMENTAL NEUROSCIENCE. ISSN 1179-0695, 2016, vol. 10, p. 31-38. ALAM, Fahmida - ISLAM, Md. Asiful - SASONGKO, Teguh Haryo - GAN, Siew Hua. Type 2 Diabetes Mellitus and Alzheimer's Disease: Bridging the Pathophysiology and Management. In CURRENT PHARMACEUTICAL DESIGN. ISSN 1381-6128, 2016, vol. 22, no. 28, p. 4430-4442. ADIELE, Reginald C. - ADIELE, Chiedukam A. Mitochondrial Regulatory Pathways in the Pathogenesis of Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2016, vol. 53, no. 4, p. 1257-1270. AVILA, Jesus - PALLAS, Noemi - BOLOS, Marta - LAURA SAYAS, C. - HERNANDEZ, Felix. Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies. In EXPERT OPINION ON THERAPEUTIC TARGETS. ISSN 1472-8222, 2016, vol. 20, no. 6, p. 653-661. WU, Xi-Lin - PINA-CRESPO, Juan - ZHANG, Yun-Wu - CHEN, Xiao-Chun - XU, Hua-Xi. Tau-mediated Neurodegeneration and Potential Implications in Diagnosis and Treatment of Alzheimer's Disease. In CHINESE MEDICAL JOURNAL. ISSN 0366-6999, DEC 20 2017, vol. 130, no. 24, p. 2978-2990. KULBE, Jacqueline R. - HALL, Edward D. Chronic traumatic encephalopathy-integration of canonical traumatic brain injury secondary injury mechanisms with tau pathology. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, NOV 2017, vol. 158, p. 15-44. GRATUZE, Maud - JULIEN, Jacinthe - MORIN, Francoise - MARETTE, Andre - PLANEL, Emmanuel. Differential effects of voluntary treadmill exercise and caloric restriction on tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology fed with Western diet. In PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. ISSN 0278-5846, OCT 3 2017, vol. 79, B, p. 452-461. MA, Xiaofeng - LI, He - HE, Yating - HAO, Junwei. The emerging link between O-GlcNAcylation and neurological disorders. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, OCT 2017, vol. 74, no. 20, p. 3667-3686. GARCIA-CERRO, Susana - RUEDA, Noerni - VIDAL, Veronica - LANTIGUA, Sara - MARTINEZ-CUE, Carmen. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, OCT 2017, vol. 106, p. 76-88. QING, Guangyan - LU, Qi - LI, Xiuling - LIU, Jing - YE, Mingliang - LIANG, Xinmiao - SUN, Taolei. Hydrogen bond based smart polymer for highly selective and tunable capture of multiply phosphorylated peptides. In NATURE COMMUNICATIONS. ISSN 2041-1723, SEP 6 2017, vol. 8. LIU QIN - WANG SHUN-CHUN - DING KAN. Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine. In CHINESE JOURNAL OF NATURAL MEDICINES. ISSN 2095-6975, SEP 2017, vol. 15, no. 9, p. 641-652. CIREGIA, Federica - URBANI, Andrea - PALMISANO, Giuseppe. Extracellular Vesicles in Brain Tumors and Neurodegenerative Diseases. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, AUG 31 2017, vol. 10. DESPRES, Clement - BYRNE, Cillian - QI, Haoling - CANTRELLE, Francois-Xavier - HUVENT, Isabelle - CHAMBRAUD, Beatrice - BAULIEU, Etienne-Emile - JACQUOT, Yves - LANDRIEU, Isabelle - LIPPENS, Guy - SMET-NOCCA, Caroline. Identification of the Tau phosphorylation pattern that drives its aggregation. In PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ISSN 0027-8424, AUG 22 2017, vol. 114, no. 34, p. 9080-9085. GUO, Xiao-dan - SUN, Guang-long - ZHOU, Ting-ting - WANG, Yi-yang - XU, Xin - SHI, Xiao-fan - ZHU, Zhi-yuan - RUKACHAISIRIKUL, Vatcharin - HU, Li-hong - SHEN, Xu. LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy. In ACTA PHARMACOLOGICA SINICA. ISSN 1671-4083, AUG 2017, vol. 38, no. 8, p. 1104-1119. RAZA, Farheen - MCGOURAN, Joanna F. - KESSLER, Benedikt M. - POSSEE, Robert D. - KING, Linda A. Phosphorylation Induces Structural Changes in the Autographa californica Nucleopolyhedrovirus P10 Protein. In JOURNAL OF VIROLOGY. ISSN 0022-538X, JUL 2017, vol. 91, no. 13. DRIES, Virginie Vanden - STYGELBOUT, Virginie - PIERROT, Nathalie - YILMAZ, Zehra - SUAIN, Valerie - DE DECKER, Robert - BUEE, Luc - OCTAVE, Jean-Noel - BRION, Jean-Pierre - LEROY, Karelle. Amyloid precursor protein reduction enhances the formation of neurofibrillary tangles in a mutant tau transgenic mouse model. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, JUL 2017, vol. 55, p. 202-212. LIU, Ying-Chun - GAO, Xiao-Xiao - ZHANG, Zhi-Guang - LIN, Zhao-Hua - ZOU, Qi-Lian. PPAR Gamma Coactivator 1 Beta (PGC-1 beta) Reduces Mammalian Target of Rapamycin (mTOR) Expression via a SIRT1-Dependent Mechanism in Neurons. In CELLULAR AND MOLECULAR NEUROBIOLOGY. ISSN 0272-4340, JUL 2017, vol. 37, no. 5, p. 879-887. NGUYEN HOANG LINH - TRAN THI MINH THU - LYANH TU - HU, Chin-Kun - LI, Mai Suan. Impact of Mutations at C-Terminus on Structures and Dynamics of A beta 40 and A beta 42: A Molecular Simulation Study. In JOURNAL OF PHYSICAL CHEMISTRY B. ISSN 1520-6106, MAY 4 2017, vol. 121, no. 17, p. 4341-4354. GRATUZE, Maud - JULIEN, Jacinthe - PETRY, Franck R. - MORIN, Francoise - PLANEL, Emmanuel. Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer's disease-like tau pathology. In SCIENTIFIC REPORTS. ISSN 2045-2322, APR 12 2017, vol. 7. DU, Zhiqiang - GONCHAROFF, Dustin Kenneth - CHENG, Xudong - LI, Liming. Analysis of [SWI+] formation and propagation events. In MOLECULAR MICROBIOLOGY. ISSN 0950-382X, APR 2017, vol. 104, no. 1, p. 105-124. ZHAO, Jing - HUVENT, Isabelle - LIPPENS, Guy - ELIEZER, David - ZHANG, Anqiang - LI, Quanhong - TESSIER, Peter - LINHARDT, Robert J. - ZHANG, Fuming - WANG, Chunyu. Glycan Determinants of Heparin-Tau Interaction. In BIOPHYSICAL JOURNAL. ISSN 0006-3495, MAR 14 2017, vol. 112, no. 5, p. 921-932. ZHANG, Zhong-Hao - WU, Qiu-Yan - ZHENG, Rui - CHEN, Chen - CHEN, Yao - LIU, Qiong - HOFFMANN, Peter R. - NI, Jia-Zuan - SONG, Guo-Li. Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, MAR 1 2017, vol. 37, no. 9, p. 2449-2462. GRATUZE, Maud - EL KHOURY, Noura B. - TURGEON, Andreanne - JULIEN, Carl - MARCOUILLER, Francois - MORIN, Francoise - WHITTINGTON, Robert A. - MARETTE, Andre - CALON, Frederic - PLANEL, Emmanuel. Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, FEB 2017, vol. 98, p. 1-8. SOMERS, Charisse - GOOSSENS, Joery - ENGELBORGHS, Sebastiaan - BJERKE, Maria. Selecting A beta isoforms for an Alzheimer's disease cerebrospinal fluid biomarker panel. In BIOMARKERS IN MEDICINE. ISSN 1752-0363, FEB 2017, vol. 11, no. 2, p. 169-178. GAWINECKA, Joanna - SCHMITZ, Matthias - ZERR, Inga. Biomarkers in Cerebrospinal Fluid. In PRION DISEASES. ISSN 0893-2336, 2017, vol. 129, p. 229-252. PETIBONE, Dayton M. - MAJEED, Waqar - CASCIANO, Daniel A. Autophagy function and its relationship to pathology, clinical applications, drug metabolism and toxicity. In JOURNAL OF APPLIED TOXICOLOGY. ISSN 0260-437X, JAN 2017, vol. 37, no. 1, p. 23-37. TAM, J. H. K. - PASTERNAK, S. H. Alzheimer's Disease. In CEREBRAL CORTEX IN NEURODEGENERATIVE AND NEUROPSYCHIATRIC DISORDERS: EXPERIMENTAL APPROACHES TO CLINICAL ISSUES. 2017, p. 83-118. GERSON, Julia E. - SENGUPTA, Urmi - KAYED, Rakez. Tau Oligomers as Pathogenic Seeds: Preparation and Propagation In Vitro and In Vivo. In TAU PROTEIN: METHODS AND PROTOCOLS. ISSN 1064-3745, 2017, vol. 1523, p. 141-157. YUZWA, Scott A. - VOCADLO, David J. Production of O-GlcNAc Modified Recombinant Tau in E. coli and Detection of Ser400 O-GlcNAc Tau In Vivo. In TAU PROTEIN: METHODS AND PROTOCOLS. ISSN 1064-3745, 2017, vol. 1523, p. 237-248. MANASSERO, Giusi - GUGLIELMOTTO, Michela - MONTELEONE, Debora - VASCIAVEO, Valeria - BUTENKO, Olena - TAMAGNO, Elena - ARANCIO, Ottavio - TABATON, Massimo. Dual Mechanism of Toxicity for Extracellular Injection of Tau Oligomers versus Monomers in Human Tau Mice. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2017, vol. 59, no. 2, p. 743-751. DE CONTI, Laura - BORRONI, Barbara - BARALLE, Marco. New routes in frontotemporal dementia drug discovery. In EXPERT OPINION ON DRUG DISCOVERY. ISSN 1746-0441, 2017, vol. 12, no. 7, p. 659-671. KRISHNAKUMAR, V.G. - BAWEJA, L. - RALHAN, K. - GUPTA, S. Carbamylation promotes amyloidogenesis and induces structural changes in Tau-core hexapeptide fibrils. In BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. ISSN 0304-4165, DEC 2018, vol. 1862, no. 12, p. 2590-2604. SAINI, R.K. - SHUAIB, S. - GOYAL, D. - GOYAL, B. Molecular insights into the effect L17A/F19A double mutation on the structure and dynamics of A beta(40): A molecular dynamics simulation study. In JOURNAL OF CELLULAR BIOCHEMISTRY. ISSN 0730-2312, NOV 2018, vol. 119, no. 11, p. 8949-8961. BOURRE, G. - CANTRELLE, F.X. - KAMAH, A. - CHAMBRAUD, B. - LANDRIEU, I. - SMET-NOCCA, C. Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy. In FRONTIERS IN ENDOCRINOLOGY. ISSN 1664-2392, OCT 16 2018, vol. 9. ZHANG, X. - GAO, F. - WANG, D.D. - LI, C. - FU, Y. - HE, W. - ZHANG, J.M. Tau Pathology in Parkinson's Disease. In FRONTIERS IN NEUROLOGY. ISSN 1664-2295, OCT 2 2018, vol. 9. JEMBREK, M.J. - SLADE, N. - HOF, P.R. - SIMIC, G. The interactions of p53 with tau and A beta as potential therapeutic targets for Alzheimer's disease. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, SEP 2018, vol. 168, p. 104-127. KHAN, R.I. - NIRZHOR, S.S.R. - RASHID, B. A Closer Look into the Role of Protein Tau in the Identification of Promising Therapeutic Targets for Alzheimer's Disease. In BRAIN SCIENCES. ISSN 2076-3425, SEP 2018, vol. 8, no. 9. CAO, L. - LIANG, Y. - LIU, Y.S. - XU, Y.X. - WAN, W.B. - ZHU, C.Q. Pseudo-phosphorylation at AT8 epitopes regulates the tau truncation at aspartate 421. In EXPERIMENTAL CELL RESEARCH. ISSN 0014-4827, SEP 1 2018, vol. 370, no. 1, p. 103-115. SONAWANE, S.K. - CHINNATHAMBI, S. Prion-Like Propagation of Post-Translationally Modified Tau in Alzheimer's Disease: A Hypothesis. In JOURNAL OF MOLECULAR NEUROSCIENCE. ISSN 0895-8696, AUG 2018, vol. 65, no. 4, p. 480-490. PHAM, D.Q.H. - LI, M.S. - LA PENNA, G. Copper Binding Induces Polymorphism in Amyloid-beta Peptide: Results of Computational Models. In JOURNAL OF PHYSICAL CHEMISTRY B. ISSN 1520-6106, JUL 26 2018, vol. 122, no. 29, p. 7243-7252. PEREZ, M.J. - JARA, C. - QUINTANILLA, R.A. Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration. In FRONTIERS IN NEUROSCIENCE. ISSN 1662-453X, JUL 5 2018, vol. 12. HAJ, E. - LOSEV, Y. - KRISHNAKUMAR, V.G. - PICHINUK, E. - ENGEL, H. - RAVEH, A. - GAZIT, E. - SEGAL, D. Integrating in vitro and in silico approaches to evaluate the "dual functionality" of palmatine chloride in inhibiting and disassembling Tau derived VQIVYK peptide fibrils. In BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. ISSN 0304-4165, JUL 2018, vol. 1862, no. 7, p. 1565-1575. SARKAR, S. Neurofibrillary tangles mediated human neuronal tauopathies: insights from fly models. In JOURNAL OF GENETICS. ISSN 0022-1333, JUL 2018, vol. 97, no. 3, SI, p. 783-793. LO CASCIO, F. - KAYED, R. Azure C Targets and Modulates Toxic Tau Oligomers. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, JUN 2018, vol. 9, no. 6, p. 1317-1326. DUAN, J.H. - MARCELLUS, K.A. - QIN, X.K. - WANG, Y.L. - PAUDEL, H.K. Cystatin C promotes tau protein phosphorylation and causes microtubule instability by inhibiting intracellular turnover of GSK3 beta in neurons. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, JUN 2018, vol. 89, p. 1-8. GAO, Y.L. - WANG, N. - SUN, F.R. - CAO, X.P. - ZHANG, W. - YU, J.T. Tau in neurodegenerative disease. In ANNALS OF TRANSLATIONAL MEDICINE. ISSN 2305-5839, MAY 2018, vol. 6, no. 10. SAHOO, A.K. - DANDAPAT, J. - DASH, U.C. - KANHAR, S. Features and outcomes of drugs for combination therapy as multi-targets strategy to combat Alzheimer's disease. In JOURNAL OF ETHNOPHARMACOLOGY. ISSN 0378-8741, APR 6 2018, vol. 215, p. 42-73. MUNOZ-MAYORGA, D. - GUERRA-ARAIZA, C. - TORNER, L. - MORALES, T. Tau Phosphorylation in Female Neurodegeneration: Role of Estrogens, Progesterone, and Prolactin. In FRONTIERS IN ENDOCRINOLOGY. ISSN 1664-2392, MAR 28 2018, vol. 9. YAGAMI, T. - YAMAMOTO, Y. - KOMA, H. Physiological and Pathological Roles of 15-Deoxy-Delta(12,14)-Prostaglandin J(2) in the Central Nervous System and Neurological Diseases. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, MAR 2018, vol. 55, no. 3, p. 2227-2248. SUN, G.L. - WANG, J.W. - GUO, X.D. - LEI, M. - ZHANG, Y.N. - WANG, X.C. - SHEN, X. - HU, L.H. Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease. In EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0223-5234, FEB 10 2018, vol. 145, p. 622-633. QAZI, T.J. - QUAN, Z.Z. - MIR, A. - QING, H. Epigenetics in Alzheimer's Disease: Perspective of DNA Methylation. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, FEB 2018, vol. 55, no. 2, p. 1026-1044. RIBARIC, S. Peptides as Potential Therapeutics for Alzheimer's Disease. In MOLECULES. ISSN 1420-3049, FEB 2018, vol. 23, no. 2. KRISHNAKUMAR, V.G. - PAUL, A. - GAZIT, E. - SEGAL, D. Mechanistic insights into remodeled Tau-derived PHF6 peptide fibrils by Naphthoquinone-Tryptophan hybrids. In SCIENTIFIC REPORTS. ISSN 2045-2322, JAN 8 2018, vol. 8. GULISANO, W. - MAUGERI, D. - BALTRONS, M.A. - FA, M. - AMATO, A. - PALMERI, A. - D'ADAMIO, L. - GRASSI, C. - DEVANAND, D.P. - HONIG, L.S. - PUZZO, D. - ARANCIO, O. Role of Amyloid-beta and Tau Proteins in Alzheimer's Disease: Confuting the Amyloid Cascade. In ALZHEIMER'S DISEASE: NEW BEGINNINGS. ISSN 2210-5727, 2018, vol. 6, p. 609-629. THONGLIM, P. - SUNGKARAT, W. - CHOTIPANICH, C. - SOMPHONSANE, R. - PHOEMPHOONTHANYAKIT, S. - BURANASIRI, P. The Optimized Time of F-18-THK5351 PET/CT in Normal Thai Population. In BIOPHOTONICS: PHOTONIC SOLUTIONS FOR BETTER HEALTH CARE VI. ISSN 0277-786X, 2018, vol. 10685. GULISANO, W. - MAUGERI, D. - BALTRONS, M.A. - FA, M. - AMATO, A. - PALMERI, A. - D'ADAMIO, L. - GRASSI, C. - DEVANAND, D.P. - HONIG, L.S. - PUZZO, D. - ARANCIO, O. Role of Amyloid-beta and Tau Proteins in Alzheimer's Disease: Confuting the Amyloid Cascade. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2018, vol. 64, p. S611-S631. KIM, C.T. - MYUNG, W. - LEWIS, M. - LEE, H. - KIM, S.E. - LEE, K. - LEE, C. - CHOI, J. - KIM, H. - CARROLL, B.J. - KIM, D.K. Exposure to General Anesthesia and Risk of Dementia: A Nationwide Population-Based Cohort Study. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2018, vol. 63, no. 1, p. 395-405. CHIROMA, S.M. - BAHARULDIN, M.T.H. - TAIB, C.N.M. - AMOM, Z. - JAGADEESAN, S. - MOKLAS, M.A.M. Inflammation in Alzheimer's disease: A friend or foe?. In BIOMEDICAL RESEARCH AND THERAPY. ISSN 2198-4093, 2018, vol. 5, no. 8, p. 2552-2564. WEE, M. - CHEGINI, F. - POWER, J.H.T. - MAJD, S. Tau Positive Neurons Show Marked Mitochondrial Loss and Nuclear Degradation in Alzheimer's Disease. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, 2018, vol. 15, no. 10, p. 928-937. YANG, Y. - WANG, J.Z. Nature of Tau-Associated Neurodegeneration and the Molecular Mechanisms. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2018, vol. 62, no. 3, p. 1305-1317. HECTOR, A. - MCANULTY, C. - PICHE-LEMIEUX, M.E. - ALVES-PIRES, C. - BUEE-SCHERRER, V. - BUEE, L. - BROUILLETTE, J. Tau hyperphosphorylation induced by the anesthetic agent ketamine/xylazine involved the calmodulin-dependent protein kinase II. In FASEB JOURNAL. ISSN 0892-6638, FEB 2020, vol. 34, no. 2, p. 2968-2977. PAUL, A. - LI, W.H. - VISWANATHAN, G.K. - ARAD, E. - MOHAPATRA, S. - LI, G. - JELINEK, R. - GAZIT, E. - LI, Y.M. - SEGAL, D. Tryptophan-glucosamine conjugates modulate tau-derived PHF6 aggregation at low concentrations. In CHEMICAL COMMUNICATIONS. ISSN 1359-7345, DEC 18 2019, vol. 55, no. 97, p. 14621-14624. REN, B.P. - ZHANG, Y.X. - ZHANG, M.Z. - LIU, Y.L. - ZHANG, D. - GONG, X. - FENG, Z.Q. - TANG, J.X. - CHANG, Y. - ZHENG, J. Fundamentals of cross-seeding of amyloid proteins: an introduction. In JOURNAL OF MATERIALS CHEMISTRY B. ISSN 2050-750X, DEC 14 2019, vol. 7, no. 46, p. 7267-7282. LO CASCIO, F. - PUANGMALAI, N. - ELLSWORTH, A. - BUCCHIERI, F. - PACE, A. - PICCIONELLO, A.P. - KAYED, R. Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives. In SCIENTIFIC REPORTS. ISSN 2045-2322, DEC 12 2019, vol. 9. ERCAN-HERBST, E. - EHRIG, J. - SCHONDORF, D.C. - BEHRENDT, A. - KLAUS, B. - RAMOS, B.G. - ORIOL, N.P. - WEBER, C. - EHRNHOEFER, D.E. A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer's disease brain. In ACTA NEUROPATHOLOGICA COMMUNICATIONS. ISSN 2051-5960, DEC 3 2019, vol. 7, no. 1. CILENTO, E.M. - JIN, L. - STEWART, T. - SHI, M. - SHENG, L.F. - ZHANG, J. Mass spectrometry: A platform for biomarker discovery and validation for Alzheimer's and Parkinson's diseases. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, NOV 2019, vol. 151, no. 4, SI, p. 397-416. VISWANATHAN, G.K. - PAUL, A. - GAZIT, E. - SEGAL, D. Naphthoquinone Tryptophan Hybrids: A Promising Small Molecule Scaffold for Mitigating Aggregation of Amyloidogenic Proteins and Peptides. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, OCT 17 2019, vol. 7. HATEGAN, A. - MASLIAH, E. - NATH, A. HIV and Alzheimer's disease: complex interactions of HIV-Tat with amyloid beta peptide and Tau protein. In JOURNAL OF NEUROVIROLOGY. ISSN 1355-0284, OCT 2019, vol. 25, no. 5, p. 648-660. DING, Y. - FENG, Y. - ZHU, W.W. - ZOU, Y.T. - XIE, Y. - WANG, F. - LIU, C.F. - ZHANG, Y.L. - LIU, H.H. [Gly14]-Humanin Prevents Lipid Deposition and Endothelial Cell Apoptosis in a Lectin-like Oxidized Low-density Lipoprotein Receptor-1-Dependent Manner. In LIPIDS. ISSN 0024-4201, Early Access OCT 2019 DING, Y.X. - KANG, A.R. - TANG, Q.L. - ZHAO, Y. Inhibition of HDAC6 expression decreases brain injury induced by APOE4 and A beta co-aggregation in rats. In MOLECULAR MEDICINE REPORTS. ISSN 1791-2997, OCT 2019, vol. 20, no. 4, p. 3363-3370. ALHAJRAF, F. - NESS, D. - HYE, A. - STRYDOM, A. Plasma amyloid and tau as dementia biomarkers in Down syndrome: Systematic review and meta-analyses. In DEVELOPMENTAL NEUROBIOLOGY. ISSN 1932-8451, JUL 2019, vol. 79, no. 7, p. 684-698. LEE, H.J. - YANG, S.J. Supplementation with Nicotinamide Riboside Reduces Brain Inflammation and Improves Cognitive Function in Diabetic Mice. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. SEP 1 2019, vol. 20, no. 17. SIANO, G. - CAIAZZA, M.C. - OLLA, I. - VARISCO, M. - MADARO, G. - QUERCIOLI, V. - CALVELLO, M. - CATTANEO, A. - DI PRIMIO, C. Identification of an ERK Inhibitor as a Therapeutic Drug Against Tau Aggregation in a New Cell-Based Assay. In FRONTIERS IN CELLULAR NEUROSCIENCE. AUG 21 2019, vol. 13. KIRK, R.A. - KESNER, R.P. - WANG, L.M. - WU, Q. - TOWNER, R.A. - HOFFMAN, J.M. - MORTON, K.A. Lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-beta plaque and phosphorylated tau deposition and corresponding behavioral deficits. In GEROSCIENCE. ISSN 2509-2715, AUG 2019, vol. 41, no. 4, p. 467-481. VENKATRAMANI, A. - PANDA, D. Regulation of neuronal microtubule dynamics by tau: Implications for tauopathies. In INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. ISSN 0141-8130, JUL 15 2019, vol. 133, p. 473-483. NASERI, N.N. - WANG, H. - GUO, J. - SHARMA, M. - LUO, W.J. The complexity of tau in Alzheimer's disease. In NEUROSCIENCE LETTERS. ISSN 0304-3940, JUL 13 2019, vol. 705, p. 183-194. CHANG, W.C. - HUANG, D.W. - LO, Y.M. - TEE, Q.Q. - KUO, P. - WU, J.S. - HUANG, W.C. - SHEN, Z.C. Protective Effect of Caffeic Acid against Alzheimer's Disease Pathogenesis via Modulating Cerebral Insulin Signaling, beta-Amyloid Accumulation, and Synaptic Plasticity in Hyperinsulinemic Rats. In JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. ISSN 0021-8561, JUL 10 2019, vol. 67, no. 27, p. 7684-7693. RAFII, M.S. Tau PET Imaging for Staging of Alzheimer's Disease in Down Syndrome. In DEVELOPMENTAL NEUROBIOLOGY. ISSN 1932-8451, JUL 2019, vol. 79, no. 7, p. 711-715. THONGLIM, P. - CHOTIPANICH, C. - BURANASIRI, P. Optimized uptake time of F-18-THK5351 PET/CT in normal Thai brain. In JOURNAL OF PHYSICS COMMUNICATIONS. ISSN 2399-6528, JUL 2019, vol. 3, no. 7. CHEN, J.F. - LONG, Z.M. - LI, Y.Z. - LUO, M. - LUO, S.F. - HE, G.Q. Alteration of the Wnt/GSK3/-catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model. In INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. ISSN 1107-3756, JUL 2019, vol. 44, no. 1, p. 313-323. DESPRES, C. - DI, J. - CANTRELLE, F.X. - LI, Z.Z. - HUVENT, I. - CHAMBRAUD, B. - ZHAO, J. - CHEN, J.L. - CHEN, S.G. - LIPPENS, G. - ZHANG, F.M. - LINHARDT, R. - WANG, C.Y. - KLARNER, F.G. - SCHRADER, T. - LANDRIEU, I. - BITAN, G. - SMET-NOCCA, C. Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors. In ACS CHEMICAL BIOLOGY. ISSN 1554-8929, JUN 2019, vol. 14, no. 6, p. 1363-1379. BARTHELEMY, N.R. - MALLIPEDDI, N. - MOISEYEV, P. - SATO, C. - BATEMAN, R.J. Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer's Disease. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, MAY 21 2019, vol. 11. LA PENNA, G. - LI, M.S. Computational models explain how copper binding to amyloid-beta peptide oligomers enhances oxidative pathways. In PHYSICAL CHEMISTRY CHEMICAL PHYSICS. ISSN 1463-9076, MAY 7 2019, vol. 21, no. 17, p. 8774-8784. ZHANG, J. - LAMBERT, E. - XU, Z.F. - BRIOCHE, J. - REMY, P. - PIETTRE, S.R. From Oxygen to Sulfur and Back: Difluoro-H-phosphinothioates as a Turning Point in the Preparation of Difluorinated Phosphinates: Application to the Synthesis of Modified Dinucleotides. In JOURNAL OF ORGANIC CHEMISTRY. ISSN 0022-3263, MAY 3 2019, vol. 84, no. 9, p. 5245-5260. ZEB, A. - KIM, D. - ALAM, S.I. - SON, M. - KUMAR, R. - RAMPOGU, S. - PARAMESWARAN, S. - SHELAKE, R.M. - RANA, R.M. - PARATE, S. - KIM, J.Y. - LEE, K.W. Computational Simulations Identify Pyrrolidine-2,3-Dione Derivatives as Novel Inhibitors of Cdk5/p25 Complex to Attenuate Alzheimer's Pathology. In JOURNAL OF CLINICAL MEDICINE. ISSN 2077-0383, MAY 2019, vol. 8, no. 5. TRIGO, D. - NADAIS, A. - SILVA, O.A.B.D.E. Unravelling protein aggregation as an ageing related process or a neuropathological response. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, MAY 2019, vol. 51, p. 67-77. FICHOU, Y. - AL-HILALY, Y.K. - DEVRED, F. - SMET-NOCCA, C. - TSVETKOV, P.O. - VERELST, J. - WINDERICKX, J. - GEUKENS, N. - VANMECHELEN, E. - PERROTIN, A. - SERPELL, L. - HANSEEUW, B.J. - MEDINA, M. - BUEE, L. - LANDRIEU, I. The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?. In ACTA NEUROPATHOLOGICA COMMUNICATIONS. ISSN 2051-5960, MAR 1 2019, vol. 7. STRANG, K.H. - SORRENTINO, Z.A. - RIFFE, C.J. - GORION, K.M.M. - VIJAYARAGHAVAN, N. - GOLDE, T.E. - GIASSON, B.I. Phosphorylation of serine 305 in tau inhibits aggregation. In NEUROSCIENCE LETTERS. ISSN 0304-3940, JAN 23 2019, vol. 692, p. 187-192. STANCU, I.C. - FERRAIOLO, M. - TERWEL, D. - DEWACHTER, I. Tau Interacting Proteins: Gaining Insight into the Roles of Tau in Health and Disease. In TAU BIOLOGY. ISSN 0065-2598, 2019, vol. 1184, p. 145-166. MAEDA, S. - TAKASHIMA, A. Tau Oligomers. In TAU BIOLOGY. ISSN 0065-2598, 2019, vol. 1184, p. 373-380. KAWA, I.A. - MASOOD, A. - AMIN, S. - MUSTAFA, M.F. - RASHID, F. Clinical Perspective of Posttranslational Modifications. In PROTEIN MODIFICOMICS: FROM MODIFICATIONS TO CLINICAL PERSPECTIVES. 2019, p. 37-68. GU, J.L. - CHU, D.D. - JIN, N.N. - CHEN, F. - LIU, F. Cyclic AMP-Dependent Protein Kinase Phosphorylates TDP-43 and Modulates Its Function in Tau mRNA Processing. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 70, no. 4, p. 1093-1102. BOCAI, N.I. - MARCORA, M.S. - BELFIORI-CARRASCO, L.F. - MORELLI, L. - CASTANO, E.M. Endoplasmic Reticulum Stress in Tauopathies: Contrasting Human Brain Pathology with Cellular and Animal Models. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 68, no. 2, p. 439-458. WANG, X. - ZIMMERMANN, H.R. - MA, T. Therapeutic Potential of AMP-Activated Protein Kinase in Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 68, no. 1, p. 33-38. ALMANSOUB, H.A.M.M. - TANG, H. - WU, Y. - WANG, D.Q. - MAHAMAN, Y.A.R. - WEI, N. - ALMANSOB, Y.A.M. - HE, W. - LIU, D. Tau Abnormalities and the Potential Therapy in Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 67, no. 1, p. 13-33. SAYAS, Carmen Laura. Tau-based therapies for Alzheimer's disease: Promising novel neuroprotective approaches. In Neuroprotection in Autism, Schizophrenia and Alzheimer's disease, 2019-10-16, pp. 245-272. PONCELET, Luc - ANDO, K. - VERGARA, Cristina - MANSOUR, S. - SUAIN, Valérie - YILMAZ, Z. - REYGEL, A. - GILISSEN, Emmanuel - BRION, Jean Pierre - LEROY, Karelle. A 4R tauopathy develops without amyloid deposits in aged cat brains. In Neurobiology of Aging. ISSN 01974580, 2019-09-01, 81, pp. 200-212. NISHA - PRAGATI - TANDON, Shweta - AQSA - AGGARWAL, Prerna - SARKAR, Surajit. Tau, tangles and tauopathies: Insights from Drosophila disease models. In Insights into Human Neurodegeneration: Lessons Learnt from Drosophila, 2019-01-01, pp. 223-250. WEICKERT, Sabrina - CATTANI, Julia - DRESCHER, Malte. Intrinsically disordered proteins (IDPs) studied by EPR and in-cell EPR. In Electron Paramagnetic Resonance. ISSN 14644622, 2019-01-01, 26, pp. 1-37. LI, Tingting - SHI, Huahua - ZHAO, Yan. Phosphorylation of microtubule-associated protein tau by mitogen-activated protein kinase in Alzheimer's disease. In IOP Conference Series: Materials Science and Engineering. ISSN 17578981, 2018-08-08, 394, 2, pp. LAKSHMI, Sreeja - PRAKASH, Parvathi - ESSA, Musthafa M. - QORONFLEH, Walid M. - AKBAR, Mohammed - SONG, Byoung Joon - KUMAR, Suresh S. - ELUMALAI, Preetham. Marine derived bioactive compounds for treatment of Alzheimer’s disease. In Frontiers in Bioscience Elite. ISSN 19450494, 2018-06-01, 10, 3, pp. 537-548. JEMBREK, Maja Jazvinšćak - NEWBER, Katy - ŠIMIĆ, Goran. The role of p53 in alzheimer’s disease: Impact on tau pathology. In Pathology, Prevention and Therapeutics of Neurodegenerative Disease, 2018-01-01, pp. 39-48. HUDSON, Andrew E. - HEROLD, Karl F. - HEMMINGS, Hugh C. Pharmacology of inhaled anesthetics. In Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application, 2018-01-01, pp. 217-240. RAHMAN, M.H. - AKTER, R. - BHATTACHARYA, T. - ABDEL-DAIM, M.M. - ALKAHTANI, S. - ARAFAH, M.W. - AL-JOHANI, N.S. - ALHOSHANI, N.M. - ALKERAISHAN, N. - ALHENAKY, A. - ABD-ELKADER, O.H. - EL-SEEDI, H.R. - KAUSHIK, D. - MITTAL, V. Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease. In FRONTIERS IN PHARMACOLOGY. DEC 30 2020, vol. 11. WESSELING, H. - MAIR, W. - KUMAR, M. - SCHLAFFNER, C.N. - TANG, S.J. - BEEREPOOT, P. - FATOU, B. - GUISE, A.J. - CHENG, L. - TAKEDA, S. - MUNTEL, J. - ROTUNNO, M.S. - DUJARDIN, S. - DAVIES, P. - KOSIK, K.S. - MILLER, B.L. - BERRETTA, S. - HEDREEN, J.C. - GRINBERG, L.T. - SEELEY, W.W. - HYMAN, B.T. - STEEN, H. - STEEN, J.A. Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease. In CELL. ISSN 0092-8674, DEC 10 2020, vol. 183, no. 6, p. 1699-+. GU, J.L. - LIU, F. Tau in Alzheimer's Disease: Pathological Alterations and an Attractive Therapeutic Target. In CURRENT MEDICAL SCIENCE. ISSN 2096-5230, DEC 2020, vol. 40, no. 6, p. 1009-1021. KANG, Y.J. - DIEP, Y.N. - TRAN, M. - CHO, H. Therapeutic Targeting Strategies for Early- to Late-Staged Alzheimer's Disease. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DEC 2020, vol. 21, no. 24. LERMYTE, F. Roles, Characteristics, and Analysis of Intrinsically Disordered Proteins: A Minireview. In LIFE-BASEL. DEC 2020, vol. 10, no. 12. BELBIN, O. - LEHMANN, S. - SABIDO, E. - HIRTZ, C. Editorial: Proteomics as a Tool for Biomarker and Drug Target Discovery: Improving the Diagnosis and Treatment of Neurodegenerative Diseases. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, NOV 26 2020, vol. 12. OAKLEY, S.S. - MAINA, M.B. - MARSHALL, K.E. - AL-HILALY, Y.K. - HARRINGTON, C.R. - WISCHIK, C.M. - SERPELL, L.C. Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target. In FRONTIERS IN NEUROLOGY. ISSN 1664-2295, NOV 12 2020, vol. 11. NAM, G. - LIN, Y. - LIM, M.H. - LEE, Y.H. Key Physicochemical and Biological Factors of the Phase Behavior of Tau. In CHEM. ISSN 2451-9294, NOV 5 2020, vol. 6, no. 11, p. 2924-2963. ALYENBAAWI, H. - ALLISON, W.T. - MOK, S.A. Prion-Like Propagation Mechanisms in Tauopathies and Traumatic Brain Injury: Challenges and Prospects. In BIOMOLECULES. NOV 2020, vol. 10, no. 11. DOMINGUEZ-MEIJIDE, A. - VASILI, E. - OUTEIRO, T.F. Pharmacological Modulators of Tau Aggregation and Spreading. In BRAIN SCIENCES. NOV 2020, vol. 10, no. 11. REZABAKHSH, A. - RAHBARGHAZI, R. - FATHI, F. Surface plasmon resonance biosensors for detection of Alzheimer's biomarkers; an effective step in early and accurate diagnosis. In BIOSENSORS & BIOELECTRONICS. ISSN 0956-5663, NOV 1 2020, vol. 167. ZENG, Y.F. - YANG, J. - ZHANG, B.L. - GAO, M. - SU, Z.D. - HUANG, Y.Q. The structure and phase of tau: from monomer to amyloid filament. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, MAR 2021, vol. 78, no. 5, p. 1873-1886. KARIKARI, T.K. - KEELING, S. - HILL, E. - RODRIGUEZ, J.L. - NAGEL, D.A. - BECKER, B. - HOGLUND, K. - ZETTERBERG, H. - BLENNOW, K. - HILL, E.J. - MOFFAT, K.G. Extensive Plasmid Library to Prepare Tau Protein Variants and Study Their Functional Biochemistry. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, OCT 7 2020, vol. 11, no. 19, p. 3117-3129. LIU, M.Y. - DEXHEIMER, T. - SUI, D. - HOVDE, S. - DENG, X.X. - KWOK, R. - BOCHAR, D.A. - KUO, M.H. Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions. In SCIENTIFIC REPORTS. ISSN 2045-2322, OCT 6 2020, vol. 10, no. 1. PEREA, J.R. - BOLOS, M. - AVILA, J. Microglia in Alzheimer's Disease in the Context of Tau Pathology. In BIOMOLECULES. OCT 2020, vol. 10, no. 10. FULLER, O.K. - WHITHAM, M. - MATHIVANAN, S. - FEBBRAIO, M.A. The Protective Effect of Exercise in Neurodegenerative Diseases: The Potential Role of Extracellular Vesicles. In CELLS. OCT 2020, vol. 9, no. 10. LUCEY, B.P. It's complicated: The relationship between sleep and Alzheimer's disease in humans. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, OCT 2020, vol. 144. MEREZHKO, M. - URONEN, R.L. - HUTTUNEN, H.J. The Cell Biology of Tau Secretion. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, SEP 23 2020, vol. 13. IWAYA, N. - GODA, N. - MATSUZAKI, M. - NARITA, A. - SHIGEMITSU, Y. - TENNO, T. - ABE, Y. - HOSHI, M. - HIROAKI, H. Principal component analysis of data from NMR titration experiment of uniformly N-15 labeled amyloid beta (1-42) peptide with osmolytes and phenolic compounds. In ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. ISSN 0003-9861, SEP 15 2020, vol. 690. MARRERO-WINKENS, C. - SANKARAN, C. - SCHATZL, H.M. From Seeds to Fibrils and Back: Fragmentation as an Overlooked Step in the Propagation of Prions and Prion-Like Proteins. In BIOMOLECULES. SEP 2020, vol. 10, no. 9. BRINER, A. - GOTZ, J. - POLANCO, J.C. Fyn Kinase Controls Tau Aggregation In Vivo. In CELL REPORTS. ISSN 2211-1247, AUG 18 2020, vol. 32, no. 7. NAM, Y. - KALATHINGAL, M. - SAITO, S. - LEE, J.Y. Tautomeric Effect of Histidine on beta-Sheet Formation of Amyloid Beta 1-40: 2D-IR Simulations. In BIOPHYSICAL JOURNAL. ISSN 0006-3495, AUG 18 2020, vol. 119, no. 4, p. 831-842. LIU, M.Y. - SUI, D.X. - DEXHEIMER, T. - HOVDE, S. - DENG, X.X. - WANG, K.W. - LIN, H.L. - CHIEN, H.T. - KWEON, H.K. - KUO, N.S. - AYOUB, C.A. - JIMENEZ-HARRISON, D. - ANDREWS, P.C. - KWOK, R. - BOCHAR, D.A. - KURET, J. - FORTIN, J. - TSAY, Y.G. - KUO, M.H. Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, NOV 2020, vol. 57, no. 11, p. 4704-4719. CHI, H. - SUN, L. - SHIU, R.H. - HAN, R. - HSIEH, C.P. - WEI, T.M. - LO, C.C. - CHANG, H.Y. - SANG, T.K. Cleavage of human tau at Asp421 inhibits hyperphosphorylated tau induced pathology in a Drosophila model. In SCIENTIFIC REPORTS. ISSN 2045-2322, AUG 10 2020, vol. 10, no. 1. LIANG, J.J.H. - MCKINNON, I.A. - RANKIN, C.H. The contribution ofC. elegansneurogenetics to understanding neurodegenerative diseases. In JOURNAL OF NEUROGENETICS. ISSN 0167-7063, OCT 1 2020, vol. 34, no. 3-4, SI, p. 527-548. REIMER, L. - BETZER, C. - KOFOED, R.H. - VOLBRACHT, C. - FOG, K. - KURHADE, C. - NILSSON, E. - OVERBY, A.K. - JENSEN, P.H. PKR kinase directly regulates tau expression and Alzheimer's disease-related tau phosphorylation. In BRAIN PATHOLOGY. ISSN 1015-6305, JAN 2021, vol. 31, no. 1, p. 103-119. RUZ, C. - ALCANTUD, J.L. - MONTERO, F.V. - DURAN, R. - BANDRES-CIGA, S. Proteotoxicity and Neurodegenerative Diseases. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. AUG 2020, vol. 21, no. 16. TYAGI, A. - KAMAL, M.A. - PODDAR, N.K. Integrated Pathways of COX-2 and mTOR: Roles in Cell Sensing and Alzheimer's Disease. In FRONTIERS IN NEUROSCIENCE. JUL 9 2020, vol. 14. NG, P.Y. - CHANG, I.S. - KOH, R.Y. - CHYE, S.M. Recent advances in tau-directed immunotherapy against Alzheimer's disease: an overview of pre-clinical and clinical development. In METABOLIC BRAIN DISEASE. ISSN 0885-7490, OCT 2020, vol. 35, no. 7, p. 1049-1066. VISWANATHAN, G.K. - SHWARTZ, D. - LOSEV, Y. - ARAD, E. - SHEMESH, C. - PICHINUK, E. - ENGEL, H. - RAVEH, A. - JELINEK, R. - COOPER, I. - GOSSELET, F. - GAZIT, E. - SEGAL, D. Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer's disease-like symptoms in animal model. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, JUL 2020, vol. 77, no. 14, p. 2795-2813. XIA, Y.X. - PROKOP, S. - GORION, K.M.M. - KIM, J.D. - SORRENTINO, Z.A. - BELL, B.M. - MANAOIS, A.N. - CHAKRABARTY, P. - DAVIES, P. - GIASSON, B.I. Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies. In ACTA NEUROPATHOLOGICA COMMUNICATIONS. ISSN 2051-5960, JUN 22 2020, vol. 8, no. 1. WU, S.S. - DU, L.F. Protein Aggregation in the Pathogenesis of Ischemic Stroke. In CELLULAR AND MOLECULAR NEUROBIOLOGY. ISSN 0272-4340, AUG 2021, vol. 41, no. 6, p. 1183-1194. RAFII, M.S. Alzheimer's Disease in Down Syndrome: Progress in the Design and Conduct of Drug Prevention Trials. In CNS DRUGS. ISSN 1172-7047, AUG 2020, vol. 34, no. 8, p. 785-794. PARK, J. - LAI, M.K.P. - ARUMUGAM, T.V. - JO, D.G. O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease. In NEUROMOLECULAR MEDICINE. ISSN 1535-1084, JUN 2020, vol. 22, no. 2, p. 171-193. LIU, H.L. - ZHONG, H.Y. - XU, Z.R. - ZHANG, Q.Q. - SHAH, S.J.A. - LIU, H.X. - YAO, X.J. The misfolding mechanism of the key fragment R3 of tau protein: a combined molecular dynamics simulation and Markov state model study. In PHYSICAL CHEMISTRY CHEMICAL PHYSICS. ISSN 1463-9076, MAY 21 2020, vol. 22, no. 19, p. 10968-10980. DILLON, G.M. - HENDERSON, J.L. - BAO, C.N. - JOYCE, J.A. - CALHOUN, M. - AMARAL, B. - KING, K.W. - BAJRAMI, B. - RABAH, D. Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites. In PLOS ONE. ISSN 1932-6203, APR 7 2020, vol. 15, no. 4. GUISLE, I. - GRATUZE, M. - PETRY, S. - MORIN, F. - KERAUDREN, R. - WHITTINGTON, R.A. - HEBERT, S.S. - MONGRAIN, V. - PLANEL, E. Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature. In SLEEP. ISSN 0161-8105, APR 2020, vol. 43, no. 4. LI, X.K. - LU, J. - XU, Y.X. - WANG, J.Y. - QIU, X.X. - FAN, L. - LI, B.L. - LIU, W.W. - MAO, F. - ZHU, J. - SHEN, X. - LI, J. Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease. In ACTA PHARMACEUTICA SINICA B. ISSN 2211-3835, APR 2020, vol. 10, no. 4, p. 646-666. KUMAR, P.S. - DHIRAVIAM, N.D. A system-level approach to investigate alloxan-induced toxicity in microtubule-binding protein to lead type 2 diabetes mellitus. In MOLECULAR DIVERSITY. ISSN 1381-1991, MAY 2021, vol. 25, no. 2, p. 911-924. SATHE, G. - MANGALAPARTHI, K.K. - JAIN, A. - DARROW, J. - TRONCOSO, J. - ALBERT, M. - MOGHEKAR, A. - PANDEY, A. Multiplexed Phosphoproteomic Study of Brain in Patients with Alzheimer's Disease and Age-Matched Cognitively Healthy Controls. In OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY. ISSN 1536-2310, APR 1 2020, vol. 24, no. 4, p. 216-227. RODRIGUEZ-CALLEJAS, J.D. - FUCHS, E. - PEREZ-CRUZ, C. Increased oxidative stress, hyperphosphorylation of tau, and dystrophic microglia in the hippocampus of aged Tupaia belangeri. In GLIA. ISSN 0894-1491, SEP 2020, vol. 68, no. 9, p. 1775-1793. AASETH, J. - BUHA, A. - WALLACE, D.R. - BJORKLUND, G. Xenobiotics, Trace Metals and Genetics in the Pathogenesis of Tauopathies. In INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. FEB 2020, vol. 17, no. 4. LI, C. - LIU, W.Z. - LI, X.H. - ZHANG, Z.H. - QI, H.X. - LIU, S.J. - YAN, N.N. - XING, Y. - HOLSCHER, C. - WANG, Z.J. The novel GLP-1/GIP analogue DA5-CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD. In BRAIN AND BEHAVIOR. ISSN 2162-3279, MAR 2020, vol. 10, no. 3. SAYAS, C.L. Tau-based therapies for Alzheimer's disease: Promising novel neuroprotective approaches. In NEUROPROTECTION IN AUTISM, SCHIZOPHRENIA AND ALZHEIMER'S DISEASE. 2020, p. 245-272. SODERBOM, G. - ZENG, B.Y. The NLRP3 inflammasome as a bridge between neuroinflammation in metabolic and neurodegenerative diseases. In METABOLIC AND BIOENERGETIC DRIVERS OF NEURODEGENERATIVE DISEASE: NEURODEGENERATIVE DISEASE RESEARCH AND COMMONALITIES WITH METABOLIC DISEASES. ISSN 0074-7742, 2020, vol. 154, p. 345-391. BEAUCHAMP, L.C. - LIU, X.M. - SEDJAHTERA, A. - BOGESKI, M. - VELLA, L.J. - BUSH, A.I. - ADLARD, P.A. - BARNHAM, K.J. S-Adenosylmethionine Rescues Cognitive Deficits in the rTg4510 Animal Model by Stabilizing Protein Phosphatase 2A and Reducing Phosphorylated Tau. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2020, vol. 77, no. 4, p. 1705-1715. CALFIO, C. - GONZALEZ, A. - SINGH, S.K. - ROJO, L.E. - MACCIONI, R.B. The Emerging Role of Nutraceuticals and Phytochemicals in the Prevention and Treatment of Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2020, vol. 77, no. 1, p. 33-51. SHARMA, V.K. - MEHTA, V. - SINGH, T.G. Alzheimer's Disorder: Epigenetic Connection and Associated Risk Factors. In CURRENT NEUROPHARMACOLOGY. ISSN 1570-159X, 2020, vol. 18, no. 8, p. 740-753. GUPTA, S.P. - PATIL, V.M. Recent Studies on Design and Development of Drugs Against Alzheimer's Disease (AD) Based on Inhibition of BACE-1 and Other AD-causative Agents. In CURRENT TOPICS IN MEDICINAL CHEMISTRY. ISSN 1568-0266, 2020, vol. 20, no. 13, p. 1195-1213. SINNIGE, T. - STROOBANTS, K. - DOBSON, C.M. - VENDRUSCOLO, M. Biophysical studies of protein misfolding and aggregation in in vivo models of Alzheimer's and Parkinson's diseases. In QUARTERLY REVIEWS OF BIOPHYSICS. ISSN 0033-5835, 2020, vol. 49. KATSINELOS, T. - DOULBERIS, M. - POLYZOS, S.A. - PAPAEFTHYMIOU, A. - KATSINELOS, P. - KOUNTOURAS, J. Molecular Links Between Alzheimer's Disease and Gastrointestinal Microbiota: Emphasis on Helicobacter pylori Infection Involvement. In CURRENT MOLECULAR MEDICINE. ISSN 1566-5240, 2020, vol. 20, no. 1, p. 3-12. UDDIN, M.S. - KABIR, M.T. - AL MAMUN, A. - BEHL, T. - MANSOURI, R.A. - ALOQBI, A.A. - PERVEEN, A. - HAFEEZ, A. - ASHRAF, G.M. Exploring Potential of Alkaloidal Phytochemicals Targeting Neuroinflammatory Signaling of Alzheimer's Disease. In CURRENT PHARMACEUTICAL DESIGN. ISSN 1381-6128, 2021, vol. 27, no. 3, p. 357-366. Dostupné na: https://doi.org/10.2174/1381612826666200531151004. ABREHA, M.H. - OJELADE, S. - DAMMER, E.B. - MCEACHIN, Z.T. - DUONG, D.M. - GEARING, M. - BASSELL, G.J. - LAH, J.J. - LEVEY, A.I. - SHULMAN, J.M. - SEYFRIED, N.T. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. In JOURNAL OF BIOLOGICAL CHEMISTRY. JAN-JUN 2021, vol. 296. Dostupné na: https://doi.org/10.1016/j.jbc.2021.100760. CANEPA, E. - FOSSATI, S. Impact of Tau on Neurovascular Pathology in Alzheimer's Disease. In FRONTIERS IN NEUROLOGY. ISSN 1664-2295, JAN 7 2021, vol. 11. Dostupné na: https://doi.org/10.3389/fneur.2020.573324. DE SIMONE, A. - TUMIATTI, V. - ANDRISANO, V. - MILELLI, A. Glycogen Synthase Kinase 3 beta: A New Gold Rush in Anti-Alzheimer's Disease Multitarget Drug Discovery?. In JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623, JAN 14 2021, vol. 64, no. 1, p. 26-41. Dostupné na: https://doi.org/10.1021/acs.jmedchem.0c00931. CAROSI, J.M. - DENTON, D. - KUMAR, S. - SARGEANT, T.J. Retromer dysfunction at the nexus of tauopathies. In CELL DEATH AND DIFFERENTIATION. ISSN 1350-9047, MAR 2021, vol. 28, no. 3, p. 884-899. Dostupné na: https://doi.org/10.1038/s41418-020-00727-2. GARCIA-AGUILAR, A. - PALOMINO, O. - BENITO, M. - GUILLEN, C. Dietary Polyphenols in Metabolic and Neurodegenerative Diseases: Molecular Targets in Autophagy and Biological Effects. In ANTIOXIDANTS. FEB 2021, vol. 10, no. 2. Dostupné na: https://doi.org/10.3390/antiox10020142. LO CASCIO, F. - MARZULLO, P. - KAYED, R. - PICCIONELLO, A.P. Curcumin as Scaffold for Drug Discovery against Neurodegenerative Diseases. In BIOMEDICINES. FEB 2021, vol. 9, no. 2. Dostupné na: https://doi.org/10.3390/biomedicines9020173. XU, X.J. - YANG, M.S. - ZHANG, B. - NIU, F. - DONG, J.Q. - LIU, B.Y. Glucose metabolism: A link between traumatic brain injury and Alzheimer's disease. In CHINESE JOURNAL OF TRAUMATOLOGY. ISSN 1008-1275, FEB 2021, vol. 24, no. 1, p. 5-10. Dostupné na: https://doi.org/10.1016/j.cjtee.2020.10.001. PAUL, A. - VISWANATHAN, G.K. - HUBER, A. - ARAD, E. - ENGEL, H. - JELINEK, R. - GAZIT, E. - SEGAL, D. Inhibition of tau amyloid formation and disruption of its preformed fibrils by Naphthoquinone-Dopamine hybrid. In FEBS JOURNAL. ISSN 1742-464X, JUL 2021, vol. 288, no. 14, p. 4267-4290. Dostupné na: https://doi.org/10.1111/febs.15741. LIU, H.L. - LI, Q. - XIONG, C.M. - ZHONG, H.Y. - ZHANG, Q.Q. - LIU, H.X. - YAO, X.J. Uncovering the Effect of pS202/pT205/pS208 Triple Phosphorylations on the Conformational Features of the Key Fragment G192-T212 of Tau Protein. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, MAR 17 2021, vol. 12, no. 6, p. 1039-1048. Dostupné na: https://doi.org/10.1021/acschemneuro.1c00058. TAN, B. - ASLAN-GULPINAR, E. - DURSUN, N. - SUER, C. N-methyl-d-aspartate receptor blockade reduces plasticity-related tau expression and phosphorylation of tau at Ser416 residue but not Thr231 residue. In EXPERIMENTAL BRAIN RESEARCH. ISSN 0014-4819, MAY 2021, vol. 239, no. 5, p. 1627-1637. Dostupné na: https://doi.org/10.1007/s00221-021-06090-z. MARTELLUCCI, S. - CLEMENTI, L. - SABETTA, S. - MUZI, P. - MATTEI, V. - BOLOGNA, M. - ANGELUCCI, A. Tau oligomers accumulation sensitizes prostate cancer cells to docetaxel treatment. In JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. ISSN 0171-5216, JUL 2021, vol. 147, no. 7, p. 1957-1971. Dostupné na: https://doi.org/10.1007/s00432-021-03598-3. BARBOLINA, M.V. Dichotomous role of microtubule associated protein tau as a biomarker of response to and a target for increasing efficacy of taxane treatment in cancers of epithelial origin. In PHARMACOLOGICAL RESEARCH. ISSN 1043-6618, MAR 2021, vol. 168. Dostupné na: https://doi.org/10.1016/j.phrs.2021.105585. ZHANG, X.H. - BAO, G.Y. - LIU, D.B. - YANG, Y. - LI, X.Z. - CAI, G.M. - LIU, Y. - WU, Y.L. The Association Between Folate and Alzheimer's Disease: A Systematic Review and Meta-Analysis. In FRONTIERS IN NEUROSCIENCE. APR 14 2021, vol. 15. Dostupné na: https://doi.org/10.3389/fnins.2021.661198. CRIST, A.M. - HINKLE, K.M. - WANG, X. - MOLONEY, C.M. - MATCHETT, B.J. - LABUZAN, S.A. - FRANKENHAUSER, I. - AZU, N.O. - LIESINGER, A.M. - LESSER, E.R. - SERIE, D.J. - QUICKSALL, Z.S. - PATEL, T.A. - CARNWATH, T.P. - DETURE, M. - TANG, X.J. - PETERSEN, R.C. - DUARA, R. - GRAFF-RADFORD, N.R. - ALLEN, M. - CARRASQUILLO, M.M. - LI, H. - ROSS, O.A. - ERTEKIN-TANER, N. - DICKSON, D.W. - ASMANN, Y.W. - CARTER, R.E. - MURRAY, M.E. Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer's disease. In NATURE COMMUNICATIONS. ISSN 2041-1723, APR 19 2021, vol. 12, no. 1. Dostupné na: https://doi.org/10.1038/s41467-021-22399-3. BAMBERGER, C. - PANKOW, S. - MARTINEZ-BARTOLOME, S. - MA, M. - DIEDRICH, J. - RISSMAN, R.A. - YATES, I.I.I. Protein Footprinting via Covalent Protein Painting Reveals Structural Changes of the Proteome in Alzheimer's Disease. In JOURNAL OF PROTEOME RESEARCH. ISSN 1535-3893, MAY 7 2021, vol. 20, no. 5, p. 2762-2771. Dostupné na: https://doi.org/10.1021/acs.jproteome.0c00912. CASCELLA, R. - CECCHI, C. Calcium Dyshomeostasis in Alzheimer's Disease Pathogenesis. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. MAY 2021, vol. 22, no. 9. Dostupné na: https://doi.org/10.3390/ijms22094914. KHAYACHI, A. - SCHOROVA, L. - ALDA, M. - ROULEAU, G.A. - MILNERWOOD, A.J. Posttranslational modifications & lithium's therapeutic effect-Potential biomarkers for clinical responses in psychiatric & neurodegenerative disorders. In NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. ISSN 0149-7634, AUG 2021, vol. 127, p. 424-445. Dostupné na: https://doi.org/10.1016/j.neubiorev.2021.05.002. ZHANG, X.Y. - ZOU, L. - MENG, L.X. - XIONG, M. - PAN, L.N. - CHEN, G.Q. - ZHENG, Y.F. - XIONG, J. - WANG, Z.H. - DUONG, D.M. - ZHANG, Z.H. - CAO, X.B. - WANG, T. - TANG, L. - YE, K.Q. - ZHANG, Z.T. Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction. In ELIFE. ISSN 2050-084X, MAY 21 2021, vol. 10. Dostupné na: https://doi.org/10.7554/eLife.65301. XIA, Y.X. - PROKOP, S. - GIASSON, B.I. "Don't Phos Over Tau": recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer's disease and other tauopathies. In MOLECULAR NEURODEGENERATION. JUN 5 2021, vol. 16, no. 1. Dostupné na: https://doi.org/10.1186/s13024-021-00460-5. SCHNODER, L. - TOMIC, I. - SCHWINDT, L. - HELM, D. - RETTEL, M. - SCHULZ-SCHAEFFER, W. - KRAUSE, E. - RETTIG, J. - FASSBENDER, K. - LIU, Y. P38 alpha-MAPK phosphorylates Snapin and reduces Snapin-mediated BACE1 transportation in APP-transgenic mice. In FASEB JOURNAL. ISSN 0892-6638, JUL 2021, vol. 35, no. 7. Dostupné na: https://doi.org/10.1096/fj.202100017R. MCCANN, H. - DURAND, B. - SHEPHERD, C.E. Aging-Related Tau Astrogliopathy in Aging and Neurodegeneration. In BRAIN SCIENCES. JUL 2021, vol. 11, no. 7. Dostupné na: https://doi.org/10.3390/brainsci11070927. BALANA, A.T. - PRATT, M.R. Mechanistic roles for altered O-GlcNAcylation in neurodegenerative disorders. In BIOCHEMICAL JOURNAL. ISSN 0264-6021, JUL 2021, vol. 478, no. 14, p. 2733-2758. Dostupné na: https://doi.org/10.1042/BCJ20200609. LI, Q. - XIONG, C.M. - LIU, H.L. - GE, H.Z. - YAO, X.J. - LIU, H.X. Computational Insights Into the Inhibition Mechanism of Proanthocyanidin B2 on Tau Hexapeptide (PHF6) Oligomer. In FRONTIERS IN CHEMISTRY. ISSN 2296-2646, JUL 14 2021, vol. 9. Dostupné na: https://doi.org/10.3389/fchem.2021.666043. SMEDLEY, G.D. - WALKER, K.E. - YUAN, S.H. The Role of PERK in Understanding Development of Neurodegenerative Diseases. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. AUG 2021, vol. 22, no. 15. Dostupné na: https://doi.org/10.3390/ijms22158146. GIONG, H.K. - SUBRAMANIAN, M. - YU, K. - LEE, J.S. Non-Rodent Genetic Animal Models for Studying Tauopathy: Review of Drosophila, Zebrafish, and C. elegans Models. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. AUG 2021, vol. 22, no. 16. Dostupné na: https://doi.org/10.3390/ijms22168465. XIA, Y.X. - BELL, B.M. - GIASSON, B.I. Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau-microtubule interactions and inhibits aggregation. In SCIENTIFIC REPORTS. ISSN 2045-2322, AUG 23 2021, vol. 11, no. 1. Dostupné na: https://doi.org/10.1038/s41598-021-96627-7. MONTIEL-FLORES, E. - MEJIA-GARCIA, O.A. - ORDONEZ-LIBRADO, J.L. - GUTIERREZ-VALDEZ, A.L. - ESPINOSA-VILLANUEVA, J. - DORADO-MARTINEZ, C. - REYNOSO-ERAZO, L. - TRON-ALVAREZ, R. - RODRIGUEZ-LARA, V. - AVILA-COSTA, M.R. Alzheimer-like cell death after vanadium pentoxide inhalation. In HELIYON. AUG 2021, vol. 7, no. 8. Dostupné na: https://doi.org/10.1016/j.heliyon.2021.e07856. KORECKA, M. - SHAW, L.M. Mass spectrometry-based methods for robust measurement of Alzheimer's disease biomarkers in biological fluids. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, OCT 2021, vol. 159, no. 2, SI, p. 211-233. Dostupné na: https://doi.org/10.1111/jnc.15465. SIANO, G. - FALCICCHIA, C. - ORIGLIA, N. - CATTANEO, A. - DI PRIMIO, C. Non-Canonical Roles of Tau and Their Contribution to Synaptic Dysfunction. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. SEP 2021, vol. 22, no. 18. Dostupné na: https://doi.org/10.3390/ijms221810145. KHAN, M.I. - GILPIN, K. - HASAN, F. - AL MAHMUD, K.A. - ADNAN, A. Effect of Strain Rate on Single Tau, Dimerized Tau and Tau-Microtubule Interface: A Molecular Dynamics Simulation Study. In BIOMOLECULES. SEP 2021, vol. 11, no. 9. Dostupné na: https://doi.org/10.3390/biom11091308. CORREIA, S.C. - MOREIRA, P.I. Oxygen Sensing and Signaling in Alzheimer's Disease: A Breathtaking Story!. In CELLULAR AND MOLECULAR NEUROBIOLOGY. ISSN 0272-4340, JAN 2022, vol. 42, no. 1, SI, p. 3-21. Dostupné na: https://doi.org/10.1007/s10571-021-01148-6. SOLIMAN, H.M. - GHONAIM, G.A. - GHARIB, S.M. - CHOPRA, H. - FARAG, A.K. - HASSANIN, M.H. - NAGAH, A. - EMAD-ELDIN, M. - HASHEM, N.E. - YAHYA, G. - EMAM, S.E. - HASSAN, A.E.A. - ATTIA, M.S. Exosomes in Alzheimer's Disease: From Being Pathological Players to Potential Diagnostics and Therapeutics. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. OCT 2021, vol. 22, no. 19. Dostupné na: https://doi.org/10.3390/ijms221910794. CARROLL, T. - GUHA, S. - NEHRKE, K. - JOHNSON, G.V.W. Tau Post-Translational Modifications: Potentiators of Selective Vulnerability in Sporadic Alzheimer's Disease. In BIOLOGY-BASEL. OCT 2021, vol. 10, no. 10. Dostupné na: https://doi.org/10.3390/biology10101047. KITOKA, K. - SKRABANA, R. - GASPARIK, N. - HRITZ, J. - JAUDZEMS, K. NMR Studies of Tau Protein in Tauopathies. In FRONTIERS IN MOLECULAR BIOSCIENCES. NOV 11 2021, vol. 8. Dostupné na: https://doi.org/10.3389/fmolb.2021.761227. PAN, B.L. - LU, X.T. - HAN, X. - HUAN, J.P. - GAO, D. - CUI, S.J. - JU, X.F. - ZHANG, Y.W. - XU, S.M. - SONG, J. - WANG, L.P. - ZHANG, H.F. - NIU, Q. Mechanism by Which Aluminum Regulates the Abnormal Phosphorylation of the Tau Protein in Different Cell Lines. In ACS OMEGA. ISSN 2470-1343, NOV 30 2021, vol. 6, no. 47, p. 31782-31796. Dostupné na: https://doi.org/10.1021/acsomega.1c04434. LIMORENKO, G. - LASHUEL, H.A. Revisiting the grammar of Tau aggregation and pathology formation: how new insights from brain pathology are shaping how we study and target Tauopathies. In CHEMICAL SOCIETY REVIEWS. ISSN 0306-0012, JAN 24 2022, vol. 51, no. 2, p. 513-565. Dostupné na: https://doi.org/10.1039/d1cs00127b. GUO, Y.X. - HU, Z.Y. - WANG, Z.H. Recent Advances in the Application Peptide and Peptoid in Diagnosis Biomarkers of Alzheimer's Disease in Blood. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, DEC 23 2021, vol. 14. Dostupné na: https://doi.org/10.3389/fnmol.2021.778955. HAJJO, Rima - SABBAH, Dima A. A. - ABUSARA, Osama H. H. - AL BAWAB, Abdel Qader. A Review of the Recent Advances in Alzheimer's Disease Research and the Utilization of Network Biology Approaches for Prioritizing Diagnostics and Therapeutics. In DIAGNOSTICS. DEC 2022, vol. 12, no. 12. Dostupné na: https://doi.org/10.3390/diagnostics12122975. WHELAN, Robert - BARBEY, Florentine M. - COMINETTI, Marcia R. - GILLAN, Claire M. - ROSICKA, Anna M. Developments in scalable strategies for detecting early markers of cognitive decline. In TRANSLATIONAL PSYCHIATRY. ISSN 2158-3188, NOV 9 2022, vol. 12, no. 1. Dostupné na: https://doi.org/10.1038/s41398-022-02237-w. DE FISENNE, M-A - YILMAZ, Z. - DE DECKER, R. - SUAIN, V. - BUEE, L. - ANDO, K. - BRION, J-P - LEROY, K. Alzheimer PHF-tau aggregates do not spread tau pathology to the brain via the Retino-tectal projection after intraocular injection in male mouse models. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, NOV 2022, vol. 174. Dostupné na: https://doi.org/10.1016/j.nbd.2022.105875. BOOZARI, Motahareh - HOSSEINZADEH, Hossein. Crocin molecular signaling pathways at a glance: A comprehensive review. In PHYTOTHERAPY RESEARCH. ISSN 0951-418X, OCT 2022, vol. 36, no. 10, p. 3859-3884. Dostupné na: https://doi.org/10.1002/ptr.7583. LIM, Yehjun - LI, Yanmei. Chemical Synthesis/Semisynthesis of Post-Translational Modified Tau Protein. In PROGRESS IN CHEMISTRY. ISSN 1005-281X, AUG 20 2022, vol. 34, no. 8, p. 1645-1660. Dostupné na: https://doi.org/10.7536/PC211012. KUMARI, Kritika - SINGH, Khuraijam Surjalal - SINGH, Kuldeep - BAKHSHI, Radhika - SINGH, Laishram Rajendrakumar. TMAO to the rescue of pathogenic protein variants. In BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. ISSN 0304-4165, NOV 2022, vol. 1866, no. 11. Dostupné na: https://doi.org/10.1016/j.bbagen.2022.130214. BARTOLOME, Fernando - CARRO, Eva - ALQUEZAR, Carolina. Oxidative Stress in Tauopathies: From Cause to Therapy. In ANTIOXIDANTS. AUG 2022, vol. 11, no. 8. Dostupné na: https://doi.org/10.3390/antiox11081421. LI, Longfei - JIANG, Yanli - WU, Gang - MAHAMAN, Yacoubou Abdoul Razak - KE, Dan - WANG, Qun - ZHANG, Bin - WANG, Jian-Zhi - LI, Hong-Lian - LIU, Rong - WANG, Xiaochuan. Phosphorylation of Truncated Tau Promotes Abnormal Native Tau Pathology and Neurodegeneration. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, OCT 2022, vol. 59, no. 10, p. 6183-6199. Dostupné na: https://doi.org/10.1007/s12035-022-02972-7. VACCHI, Elena - LAZZARINI, Edoardo - PINTON, Sandra - CHIARO, Giacomo - DISANTO, Giulio - MARCHI, Francesco - ROBERT, Thomas - STAEDLER, Claudio - GALATI, Salvatore - GOBBI, Claudio - BARILE, Lucio - KAELIN-LANG, Alain - MELLI, Giorgia. Tau protein quantification in skin biopsies differentiates tauopathies from alpha-synucleinopathies. In BRAIN. ISSN 0006-8950, AUG 27 2022, vol. 145, no. 8, p. 2755-2768. Dostupné na: https://doi.org/10.1093/brain/awac161. MAI, Meiting - GUO, Xiaorou - HUANG, Yue - ZHANG, Wenbin - XU, Yixuan - ZHANG, Ying - BAI, Xiaojing - WU, Junfeng - ZU, Hengbing. DHCR24 Knockdown Induces Tau Hyperphosphorylation at Thr181, Ser199, Ser262, and Ser396 Sites via Activation of the Lipid Raft-Dependent Ras/MEK/ERK Signaling Pathway in C8D1A Astrocytes. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, SEP 2022, vol. 59, no. 9, p. 5856-5873. Dostupné na: https://doi.org/10.1007/s12035-022-02945-w. BICH-HANH THI NGUY - LIU, Wen-Te - CHANG, Yu-Tai - LIN, Chih-Peng - KANG, Jiunn-Horng. Elevated tau and β-amyloid in the serum of fibromyalgia patients. In CNS SPECTRUMS. ISSN 1092-8529, JUN 2022, vol. 27, no. 3, p. 339-346. Dostupné na: https://doi.org/10.1017/S1092852920002114. MENG, Jonathan X. - ZHANG, Yu - SAMAN, Dominik - HAIDER, Arshad M. - DE, Suman - SANG, Jason C. - BROWN, Karen - JIANG, Kun - HUMPHREY, Jane - JULIAN, Linda - HIDARI, Eric - LEE, Steven F. - BALMUS, Gabriel - FLOTO, R. Andres - BRYANT, Clare E. - BENESCH, Justin L. P. - YE, Yu - KLENERMAN, David. Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses. In NATURE COMMUNICATIONS. MAY 16 2022, vol. 13, no. 1. Dostupné na: https://doi.org/10.1038/s41467-022-30461-x. LANDRIEU, Isabelle - DUPRE, Elian - SINNAEVE, Davy - EL HAJJAR, Lea - SMET-NOCCA, Caroline. Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools. In FRONTIERS IN CHEMISTRY. ISSN 2296-2646, MAY 12 2022, vol. 10. Dostupné na: https://doi.org/10.3389/fchem.2022.886382. XIA, Yuxing - PROKOP, Stefan - BELL, Brach M. - GORION, Kimberly-Marie M. - CROFT, Cara L. - NASIF, Lith - XU, Guilian - RIFFE, Cara J. - MANAOIS, Alyssa N. - STRANG, Kevin H. - QUINTIN, Stephan S. - PATERNO, Giavanna - TANSEY, Malu Gamez - BORCHELT, David R. - GOLDE, Todd E. - GIASSON, Benoit, I. Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice. In COMMUNICATIONS BIOLOGY. MAY 12 2022, vol. 5, no. 1. Dostupné na: https://doi.org/10.1038/s42003-022-03373-1. CONGDON, Erin E. - JIANG, Yixiang - SIGURDSSON, Einar M. Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly. In SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. ISSN 1084-9521, JUN 2022, vol. 126, SI, p. 125-137. Dostupné na: https://doi.org/10.1016/j.semcdb.2021.12.002. PICCARDO, Pedro - CERVENAK, Juraj - GOLDMANN, Wilfred - STEWART, Paula - POMEROY, Kitty L. - GREGORI, Luisa - YAKOVLEVA, Oksana - ASHER, David. Experimental Bovine Spongiform Encephalopathy in Squirrel Monkeys: The Same Complex Proteinopathy Appearing after Very Different Incubation Times. In PATHOGENS. MAY 2022, vol. 11, no. 5. Dostupné na: https://doi.org/10.3390/pathogens11050597. HUANG, Li-Kai - CHAO, Shu-Ping - HU, Chaur-Jong - CHIEN, Li-Nien - CHIOU, Hung-Yi - LO, Yu-Chun - HSIEH, Yi-Chen. Plasma Phosphorylated-tau181 Is a Predictor of Post-stroke Cognitive Impairment: A Longitudinal Study. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, APR 29 2022, vol. 14. Dostupné na: https://doi.org/10.3389/fnagi.2022.889101. NANDY P - JACOBS T L K - TIMMERS M - GALPERN W R - LI L - TIMOTHY M - NANDI P - LEE L. Reducing total cerebrospinal fluid p217+tau in subject in need for treating Alzehimer's disease, involves administering to subject composition comprising carrier and specific dose of monoclonal antibody composed of heavy chain and light chain variable complementarity-determining region. US2022127345-A1; WO2022090158-A1; TW202233666-A; CA3199806-A1; AU2021367878-A1; IL302386-A; KR2023093499-A; BR112023007848-A2; EP4232155-A1; CN116916955-A; JP2023546504-W. PEREZ R C - NANDY P - HENLEY D B - HENLEY D - RUIXO C P - LI L - HENRY D - NANDI P - LUISO C P - LEE L. Administering monoclonal antibody to subject used for treatment of Alzheimer's disease, involves administering pharmaceutical composition comprises heavy chain variable complementarity-determining region, and carrier. US2022127346-A1; WO2022090169-A1; TW202231661-A; CA3199808-A1; IL302383-A; AU2021370222-A1; KR2023097110-A; BR112023007840-A2; EP4232472-A1; CN116829582-A; JP2023546503-W. KHAN, Muhammad Imran - KHAN, Muhammad Zubair - SHIN, Jin Hyuk - SHIN, Tai Sun - LEE, Young Bok - KIM, Min Yong - KIM, Jong Deog. Neuroprotective Effects of Green Tea Seed Isolated Saponin Due to the Amelioration of Tauopathy and Alleviation of Neuroinflammation: A Therapeutic Approach to Alzheimer's Disease. In MOLECULES. APR 2022, vol. 27, no. 7. Dostupné na: https://doi.org/10.3390/molecules27072079. YE, Haiqiong - HAN, Yue - LI, Ping - SU, Zhengding - HUANG, Yongqi. The Role of Post-Translational Modifications on the Structure and Function of Tau Protein. In JOURNAL OF MOLECULAR NEUROSCIENCE. ISSN 0895-8696, AUG 2022, vol. 72, no. 8, p. 1557-1571. Dostupné na: https://doi.org/10.1007/s12031-022-02002-0. WU, Lidan - ZHAO, Na - JIANG, Wenjie - WANG, Fengshan. Effects of heparan sulfate from porcine mucosa on Aβsub1-42/sub-induced neurotoxicity iin vitro/i and iin vivo/i. In INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. ISSN 0141-8130, MAY 1 2022, vol. 206, p. 823-836. Dostupné na: https://doi.org/10.1016/j.ijbiomac.2022.03.079. SHAMS, Hengameh - MATSUNAGA, Atsuko - MA, Qin - MOFRAD, Mohammad R. K. - DIDONNA, Alessandro. Methylation at a conserved lysine residue modulates tau assembly and cellular functions. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, MAY 2022, vol. 120. Dostupné na: https://doi.org/10.1016/j.mcn.2022.103707. VILLAVICENCIO-TEJO, Francisca - OLESEN, Margrethe A. - ARANGUIZ, Alejandra - QUINTANILLA, Rodrigo A. Activation of the Nrf2 Pathway Prevents Mitochondrial Dysfunction Induced by Caspase-3 Cleaved Tau: Implications for Alzheimer's Disease. In ANTIOXIDANTS. MAR 2022, vol. 11, no. 3. Dostupné na: https://doi.org/10.3390/antiox11030515. BERA, Arpita - LAVANYA, Gantyada - RESHMI, Ravada - DEV, Kapil - KUMAR, Rahul. Mechanistic and therapeutic role of Drp1 in the pathogenesis of Alzheimer's disease. In EUROPEAN JOURNAL OF NEUROSCIENCE. ISSN 0953-816X, NOV 2022, vol. 56, no. 9, SI, p. 5516-5531. Dostupné na: https://doi.org/10.1111/ejn.15611. SNEDDEN, A. M. - KELLETT, K. A. B. - LILLEKER, J. B. - HOOPER, N. M. - CHINOY, H. The role of protein aggregation in the pathogenesis of inclusion body myositis. In CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. ISSN 0392-856X, FEB 2022, vol. 40, no. 2, p. 414-424. KUMAR, Rahul - TIWARI, Vishvanath - DEY, Sharmistha. Role of proline-rich tyrosine kinase 2 (Pyk2) in the pathogenesis of Alzheimer's disease. In EUROPEAN JOURNAL OF NEUROSCIENCE. ISSN 0953-816X, NOV 2022, vol. 56, no. 9, SI, p. 5442-5452. Dostupné na: https://doi.org/10.1111/ejn.15569. GANGULY, Devargya - THOMAS, Joshua Abby - ALI, Abid - KUMAR, Rahul. Mechanistic and therapeutic implications of EphA-4 receptor tyrosine kinase in the pathogenesis of Alzheimer's disease. In EUROPEAN JOURNAL OF NEUROSCIENCE. ISSN 0953-816X, NOV 2022, vol. 56, no. 9, SI, p. 5532-5546. Dostupné na: https://doi.org/10.1111/ejn.15591. EZERSKIY, Lubov A. - SCHOCH, Kathleen M. - SATO, Chihiro - BELTCHEVA, Mariana - HORIE, Kanta - RIGO, Frank - MARTYNOWICZ, Ryan - KARCH, Celeste M. - BATEMAN, Randall J. - MILLER, Timothy M. Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction. In JCI INSIGHT. JAN 11 2022, vol. 7, no. 1. Dostupné na: https://doi.org/10.1172/jci.insight.152012. DAILY, Kylene P. Gene Regulatory Mechanisms Underlying Microglial Dysfunction in Alzheimer's Disease. Jan 01 2022. MOROZOVA, Viktoriya. Mechanism of Tau Propagation: Putative Therapeutic Approaches. Jan 01 2022. OCAñAS, SarahRenee. Epigenetic Regulation of Sexually Divergent Neuroinflammation with Brain Aging and Alzheimer’s Disease. Jan 01 2022. RYBNICEK, Jonas. Common Genetic Variants in emCHRNA5/em Alter β-Amyloid Neuropathology and Highlight Chandelier Cells in Human Aging and Alzheimer’s Disease. Jan 01 2022. YAN, Yan. X-Linked Ubiquitin-Specific Peptidase 11 Increases Tauopathy Vulnerability in Women. Jan 01 2022. ZENG, Zhikai. Seeking the Structural Basis of Tau Seeding. Jan 01 2022. AILLAUD, Isabelle. Neue Perspektive In der Therapie der Alzheimerschen Demenz – Identifizierung und Charakterisierung von Peptiden Als Tau-Aggregationsinhibitoren. Jan 01 2022. SCHNEEWEIS, Amanda. Building an Atlas of Tau Phosphorylation Sites Involved in Synaptic Plasticity and Disease. Jan 01 2022. ATWA, Ahmed. Mapping the Tau Protein Interactome Using the BIOID2 in Situ Labelling Approach. Jan 01 2022. SALEHIPOUR, Arash - BAGHERI, Motahareh - SABAHI, Mohammadmahdi - DOLATSHAHI, Mahsa - BOCHE, Delphine. Combination Therapy in Alzheimer's Disease: Is It Time?. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2022, vol. 87, no. 4, p. 1433-1449. Dostupné na: https://doi.org/10.3233/JAD-215680. CHAUHAN, Neha - PALIWAL, Swati - JAIN, Smita - VERMA, Kanika - PALIWAL, Sarvesh - SHARMA, Swapnil. GSK-3β and its Inhibitors in Alzheimer's Disease: A Recent Update. In MINI-REVIEWS IN MEDICINAL CHEMISTRY. ISSN 1389-5575, 2022, vol. 22, no. 22, p. 2881-2895. Dostupné na: https://doi.org/10.2174/1389557522666220420094317. MEHAN, Sidharth - BHALLA, Sonalika - SIDDIQUI, Ehraz Mehmood - SHARMA, Nidhi - SHANDILYA, Ambika - KHAN, Andleeb. Potential Roles of Glucagon-Like Peptide-1 and Its Analogues in Dementia Targeting Impaired Insulin Secretion and Neurodegeneration. In DEGENERATIVE NEUROLOGICAL AND NEUROMUSCULAR DISEASE. 2022, vol. 12, p. 31-59. Dostupné na: https://doi.org/10.2147/DNND.S247153. AKERMAN, Suleyman Can. Early Biomarker Detection & Potential Novel Pathogenic Pathways of Alzheimer Disease Involving Aβ and Tau. Jan 01 2021. BANH, Andy Quang. Pathogenic Tau Oligomers Induce Endothelial Cell Senescence and Dysfunction in Models of Alzheimer's Disease. Jan 01 2021. EZERSKIY, Lubov Alexandra. Role of 4r Tau in Astrocyte-Mediated Neuronal Toxicity and the Progression of Neurodegenerative Disease. Jan 01 2021. SHAH, Ekta Jayendra. The Influence of Biological Sex, Tau and Mitochondrial Function on Traumatic Brain Injury Outcome in emDrosophila/em. Jan 01 2021. LESLIE, Shannon N. Molecular Mechanisms of Aging and Alzheimer’s Disease. Jan 01 2021. Kategória ADCA - Vedecké práce v zahraničných karentovaných časopisoch impaktovaných Kategória (od 2022) V3 - Vedecký výstup publikačnej činnosti z časopisu Typ výstupu článok Rok vykazovania 2001 Registrované v WOS Registrované v SCOPUS Registrované v CCC DOI 10.1073/pnas.121119298 
článok
rok CC IF IF Q (best) JCR Av Jour IF Perc SJR SJR Q (best) CiteScore A rok vydania rok metriky IF IF Q (best) SJR SJR Q (best) 2001
Počet záznamov: 1