Počet záznamov: 1
Hypoxia activates the capacity of tumor -associated carbonic anhydrase IX to acidify extracellular pH
Názov Hypoxia activates the capacity of tumor -associated carbonic anhydrase IX to acidify extracellular pH Autor Švastová Eliška 1975 ORCID Spoluautori Hulíková Alžbeta 1979 ORCID Baráthová Monika 1976- ORCID Zaťovičová Miriam 1958 Gibadulinová Adriana 1960 Casini A. Cecchi A. Scozzafava Andrea Supuran C.T. Pastorek Jaromír 1957- Pastoreková Silvia 1961 ORCID Zdroj.dok. FEBS Letters : Federation of European Biochemical Societies Letters for the Rapid Publication of Short Reports in Biochemistry, Biophysics and Molecular Biology. Vol. 577, no. 3 (2004), p. 439-445. - Amsterdam : Elsevier Science Publishers Jazyk dok. eng - angličtina Krajina SK - Slovenská republika Druh dok. rozpis článkov z periodík (rbx) Ohlasy Zhang Z, Tanabe K, Hatta H, Nishimoto S Bioreduction activated prodrugs of camptothecin: molecular design, synthesis, activation mechanism and hypoxia selective cytotoxicity ORGANIC & BIOMOLECULAR CHEMISTRY 3 (10): 1905-1910 2005 Griffiths EA, Pritchard SA, Welch IM, Price PM, West CM Is the hypoxia-inducible factor pathway important in gastric cancer? EUROPEAN JOURNAL OF CANCER 41 (18): 2792-2805 DEC 2005 Leppilampi M, Parkkila S, Karttunen T, Gut MO, Gros G, Sjoblom M Carbonic anhydrase isozyme-II-deficient mice lack the duodenal bicarbonate secretory response to prostaglandin E-2 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (42): 15247-15252 OCT 18 2005 Mayer A, Hockel M, Vaupel P Carbonic anhydrase IX expression and tumor oxygenation status do not correlate at the microregional level in locally-advanced cancers of the uterine cervix CLINICAL CANCER RESEARCH 11 (20): 7220-7225 OCT 15 2005 Kummola L, Hamalainen JM, Kivela J, Kivela AJ, Saarnio J, Karttunen T, Parkkila S Expression of a novel carbonic anhydrase, CA XIII, in normal and neoplastic colorectal mucosa BMC CANCER 5: Art. No. 41 APR 18 2005 Purkerson JM, Schwartz GJ Expression of membrane-associated carbonic anhydrase isoforms IV, IX, XII, and XIV in the rabbit: induction of CA IV and IX during maturation AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 288 (5): R1256-R1263 MAY 2005 Koukourakis MI (Koukourakis, Michael I.), Pitiakoudis M (Pitiakoudis, Michael), Giatromanolaki A (Giatromanolaki, Alexandra), Tsarouha A (Tsarouha, Alexandra), Polychronidis A (Polychronidis, Alexandros), Sivridis E (Sivridis, Efthimios), Simopoulos C (Simopoulos, Costantinos) Oxygen and glucose consumption in gastrointestinal adenocarcinomas: Correlation with markers of hypoxia, acidity and anaerobic glycolysis CANCER SCIENCE 97 (10): 1056-1060 OCT 2006 Generali, D.a b , Fox, S.B.a , Berruti, A.d , Brizzi, M.P.d , Campo, L.a , Bonardi, S.b , Wigfield, S.M.a , Bruzzi, P.e , Bersiga, A.c , Allevi, G.b , Milani, M.b , Aguggini, S.b , Dogliotti, L.d , Bottini, A.b , Harris, A.L. Role of carbonic anhydrase IX expression in prediction of the efficacy and outcome of primary epirubicin/tamoxifen therapy for breast cancer Endocrine-Related Cancer 13 (3), pp. 921-930 , 2006 Stiehl DP (Stiehl, Daniel P.), Wirthner R (Wirthner, Renato), Koditz J (Koeditz, Jens), Spielmann P (Spielmann, Patrick), Camenisch G (Camenisch, Gieri), Wenger RH (Wenger, Roland H.) Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels - Evidence for an autoregulatory oxygen-sensing system JOURNAL OF BIOLOGICAL CHEMISTRY 281 (33): 23482-23491 AUG 18 2006 Chaves S (Chaves, Silvia), Marques SM (Marques, Sergio M.), Cachudo A (Cachudo, Anabela), Esteves MA (Esteves, M. Alexandra), Santos MA (Santos, M. Amelia. Zinc(II) complexation behaviour of sulfonamide-based enzyme inhibitors EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (19): 3853-3860 OCT 2 2006 Petibois C, Gionnet K, Goncalves M, Perromat A, Moenner M, Deleris G Analytical performances of FT-IR spectrometry and imaging for concentration measurements within biological fluids, cells, and tissues ANALYST 131 (5): 640-647 2006 Brahimi-Horn MC, Pouyssegur J Hypoxia in cancer cell metabolism and pH regulation OXYGEN SENSING AND HYPOXIA-INDUCED RESPONSES Volume: 43 Pages: 165-178 Published: 2007 Carney, W.P. Circulating oncoproteins HER2/neu, EGFR and CAIX (MN) as novel cancer biomarkers Expert Review of Molecular Diagnostics 7 (3), pp. 309-319 , 2007 Eui, J.M., Brizel, D.M., Chi, J.-T.A., Dewhirst, M.W. The potential role of intrinsic hypoxia markers as prognostic variables in cancer Antioxidants and Redox Signaling 9 (8), pp. 1237-1294 , 2007 Sansone, P (Sansone, Pasquale); Storci, G (Storci, Gianluca); Tavolari, S (Tavolari, Simona); Guarnieri, T (Guarnieri, Tiziana); Giovannini, C (Giovannini, Catia); Taffurelli, M (Taffurelli, Mario); Ceccarelli, C (Ceccarelli, Claudio); Santini, D (Santini, Donatella); Paterini, P (Paterini, Paola); Marcu, KB (Marcu, Kenneth B.); Chieco, P (Chieco, Pasquale); Bonafe, M (Bonafe, Massimiliano) IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland JOURNAL OF CLINICAL INVESTIGATION, 117 (12): 3988-4002 DEC 2007 Winum JY Carbonic anhydrase IX inhibitors: fluorescent sulfonamides as therapeutic and diagnostic agents EXPERT OPINION ON THERAPEUTIC PATENTS Volume: 17 Issue: 11 Pages: 1393-1396 Published: 2007 Yeung, SCJ (Yeung, Sai-Ching J.); She, MR (She, Miaorong); Yang, HL (Yang, Huiling); Pan, JX (Pan, Jingxuan); Sun, LL (Sun, Lily); Chaplin, D (Chaplin, David) Combination chemotherapy including combretastatin A4 phosphate and paclitaxel is effective against anaplastic thyroid cancer in a nude mouse xenograft model JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, 92 (8): 2902-2909 AUG 2007 Kim JW, Gao P, Dang CV Effects of hypoxia on tumor metabolism CANCER AND METASTASIS REVIEWS Volume: 26 Issue: 2 Pages: 291-298 , 2007 Swietach, P (Swietach, Pawel); Vaughan-Jones, RD (Vaughan-Jones, Richard D.); Harris, AL (Harris, Adrian L.) Regulation of tumor pH and the role of carbonic anhydrase 9 CANCER AND METASTASIS REVIEWS, 26 (2): 299-310 JUN 2007 Moon, EJ (Moon, Eui Jung); Brizel, DM (Brizel, David M.); Chi, JTA (Chi, Jen-Tsan Ashley); Dewhirst, MW (Dewhirst, Mark W.) The potential role of intrinsic hypoxia markers as prognostic variables in cancer ANTIOXIDANTS & REDOX SIGNALING, 9 (8): 1237-1294 AUG 2007 Carney WP Circulating oncoproteins HER2/neu, EGFR and CAIX (MN) as novel cancer biomarkers EXPERT REVIEW OF MOLECULAR DIAGNOSTICS Volume: 7 Issue: 3 Pages: 309-319 Published: 2007 Wilson GD Hypoxia and prognosis: the oxygen tension mounts FRONTIERS IN BIOSCIENCE Volume: 12 Pages: 3502-3518 Published: 2007 Brahimi-Horn MC, Chiche J, Pouyssegur J Hypoxia signalling controls metabolic demand CURRENT OPINION IN CELL BIOLOGY Volume: 19 Issue: 2 Pages: 223-229 2007 Purkerson JM, Schwartz GJ The role of carbonic anhydrases in renal physiology KIDNEY INTERNATIONAL Volume: 71 Issue: 2 Pages: 103-115 Published: 2007 Said, HM (Said, Harun M.); Staab, A (Staab, Adrian); Hagemann, C (Hagemann, Carsten); Vince, GH (Vince, Giles H.); Katzer, A (Katzer, Astrid); Flentje, M (Flentje, Michael); Vordermark, D (Vordermark, Dirk) Distinct patterns of hypoxic expression of carbonic anhydrase IX (CA IX) in human malignant glioma cell lines JOURNAL OF NEURO-ONCOLOGY, 81 (1): 27-38 JAN 2007 Gao, BB (Gao, Ben-Bo); Clermont, A (Clermont, Allen); Rook, S (Rook, Susan); Fonda, SJ (Fonda, Stephanie J.); Srinivasan, VJ (Srinivasan, Vivek J.); Wojtkowski, M (Wojtkowski, Maciej); Fujimoto, JG (Fujimoto, James G.); Avery, RL (Avery, Robert L.); Arrigg, PG (Arrigg, Paul G.); Bursell, SE (Bursell, Sven-Erik); Aiello, LP (Aiello, Lloyd Paul); Feener, EP (Feener, Edward P.) Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation NATURE MEDICINE, 13 (2): 181-188 FEB 2007 Di Paolo, A., Bocci, G. Drug distribution in tumors: Mechanisms, role in drug resistance, and methods for modification Current Oncology Reports 9 (2), pp. 109-114 , 2007 Gao, B.-B.a , Clermont, A.a , Rook, S.a , Fonda, S.J.a b , Srinivasan, V.J.c , Wojtkowski, M.c , Fujimoto, J.G.c , Avery, R.L.d , Arrigg, P.G.e , Bursell, S.-E.a e f , Aiello, L.P.a e f , Feener, E.P. Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation Nature Medicine 13 (2), pp. 181-188 , 2007 Brahimi-Horn, M.C., Pouysségur, J. Hypoxia in cancer cell metabolism and pH regulation Essays in Biochemistry 43, pp. 165-178 , 2007 Kim, J.-W., Gao, P., Dang, C.V. Effects of hypoxia on tumor metabolism Cancer and Metastasis Reviews 26 (2), pp. 291-298, 2007 Wirthner, R., Wrann, S., Balamurugan, K., Wenger, R.H., Stiehl, D.P. Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1?-deficient mouse embryonic fibroblasts Carcinogenesis 29 (12), pp. 2306-2316 , 2008 Zhou, W.-B., Bai, M., Jin, Y., Wu, Y., Li, J. Expressions and significance of carbonic anhydrases IX and vascular endothelial growth factor in non-small cell lung cancer Chinese Journal of Cancer Prevention and Treatment 15 (16), pp. 1251-1254 , 2008 Dai HY (Dai, Huei-Yue)1,2, Hong CC (Hong, Chih-Chen)1,2, Liang SC (Liang, San-Chi)3,4, Yan MD (Yan, Ming-De)1, Lai GM (Lai, Gi-Ming)1, Cheng AL (Cheng, Ann-Lii)1,5,6, Chuang SE (Chuang, Shuang-En)1 Carbonic Anhydrase III Promotes Transformation and Invasion Capability in Hepatoma Cells Through FAK Signaling Pathway MOLECULAR CARCINOGENESIS Volume: 47 Issue: 12 Pages: 956-963 Published: DEC 2008 Tanaka N (Tanaka, N.)1, Kato H (Kato, H.)1, Inose T (Inose, T.)1, Kimura H (Kimura, H.)1, Faried A (Faried, A.)1, Sohda M (Sohda, M.)1, Nakajima M (Nakajima, M.)1, Fukai Y (Fukai, Y.)1, Miyazaki T (Miyazaki, T.)1, Masuda N (Masuda, N.)1, Fukuchi M (Fukuchi, M.)1, Kuwano H (Kuwano, H.) Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma BRITISH JOURNAL OF CANCER Volume: 99 Issue: 9 Pages: 1468-1475 Published: OCT 28 2008 Guler OO (Guler, O. Ozensoy)1, Arslan O (Arslan, O.)1, Kockar F (Kockar, F.)2 Differential in vitro inhibitory effects of anticancer drugs on tumor-associated carbonic anhydrase isozymes CA IX and CA XII METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY Volume: 30 Issue: 5 Pages: 335-340 Published: JUN 2008 Alchera E (Alchera, Elisa)1, Tacchini L (Tacchini, Lorenza)2, Imarisio C (Imarisio, Chiara)1, Dal Ponte C (Dal Ponte, Caterina)1, De Ponti C (De Ponti, Cristina)2, Gammella E (Gammella, Elena)2, Cairo G (Cairo, Gaetano)2, Albano E (Albano, Emanuele)1, Carini R (Carini, Rita)1 Adenosine-dependent activation of hypoxia-inducible factor-1 induces late preconditioning in liver cells HEPATOLOGY Volume: 48 Issue: 1 Pages: 230-239 Published: JUL 2008 Gillies RJ (Gillies, Robert J.)1, Robey I (Robey, Ian)1, Gatenby RA (Gatenby, Robert A.)1 Causes and consequences of increased glucose metabolism of cancers JOURNAL OF NUCLEAR MEDICINE Volume: 49 Pages: 24S-42S Supplement: Suppl. 2 Published: JUN 2008 Parkkila S Significance of pH regulation and carbonic anhydrases in tumour progression and implications for diagnostic and therapeutic approaches BJU INTERNATIONAL Volume: 101 Pages: 16-21 Supplement: Suppl. 4 Published: JUN 2008 Krishnamurthy VM (Krishnamurthy, Vijay M.)1, Kaufman GK (Kaufman, George K.)1, Urbach AR (Urbach, Adam R.)1, Gitlin I (Gitlin, Irina)1, Gudiksen KL (Gudiksen, Katherine L.)1, Weibel DB (Weibel, Douglas B.)1, Whitesides GM (Whitesides, George M.)1 Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding CHEMICAL REVIEWS Volume: 108 Issue: 3 Pages: 946-1051 Published: MAR 2008 Sansone P (Sansone, Pasquale)1,2, Piazzi G (Piazzi, Giulia)1,5, Paterini P (Paterini, Paola)1,4,5, Strillacci A (Strillacci, Antonio)4, Ceccarelli C (Ceccarelli, Claudio)5, Minni F (Minni, Francesco)6, Biasco G (Biasco, Guido)7, Chieco P (Chieco, Pasquale)1, Bonafe M (Bonafe, Massimiliano)1,3 Cyclooxygenase-2/carbonic anhydrase-IX up-regulation promotes invasive potential and hypoxia survival in colorectal cancer cells JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Volume: 13 Issue: 9B Pages: 3876-3887 Published: SEP 2009 Hoogsteen IJ (Hoogsteen, Ilse J.)1, Lok J (Lok, Jasper)1, Marres HAM (Marres, Henri A. M.)2, Takes RP (Takes, Robert P.)2, Rijken PFJW (Rijken, Paul F. J. W.)2, van der Kogel AJ (van der Kogel, Albert J.)1, Kaanders JHAM (Kaanders, Johannes H. A. M.)1 Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia EUROPEAN JOURNAL OF CANCER Volume: 45 Issue: 16 Pages: 2906-2914 Published: NOV 2009 Sharma BK (Sharma, Brij Kishore)1, Pilania P (Pilania, Pradeep)1, Singh P (Singh, Prithvi)1, Sharma S (Sharma, Susheela)2, Prabhakar YS (Prabhakar, Yenamandra S.)3 CP-MLR directed QSAR study of carbonic anhydrase inhibitors: sulfonamide and sulfamate inhibitors CENTRAL EUROPEAN JOURNAL OF CHEMISTRY Volume: 7 Issue: 4 Pages: 909-922 Published: DEC 2009 van den Beucken T (van den Beucken, Twan)1,2, Ramaekers CHMA (Ramaekers, Chantal H. M. A.)2, Rouschop K (Rouschop, Kasper)1, Koritzinsky M (Koritzinsky, Marianne)1,2,3,4,5, Wouters BG (Wouters, Bradly G.)1,2,3,4,5 Deficient carbonic anhydrase 9 expression in UPR-impaired cells is associated with reduced survival in an acidic microenvironment RADIOTHERAPY AND ONCOLOGY Volume: 92 Issue: 3 Special Issue: Sp. Iss. SI Pages: 437-442 Published: SEP 2009 Yildirim H, Kockar F TGF-beta upregulates tumor-associated carbonic anhydrase IX gene expression in Hep3B cells CELL BIOLOGY INTERNATIONAL Volume: 33 Issue: 9 Pages: 1002-1007 Published: SEP 2009 Ahlskog JKJ (Ahlskog, J. K. J.)1, Schliemann C (Schliemann, C.)1, Marlind J (Marlind, J.)1, Qureshi U (Qureshi, U.)2, Ammar A (Ammar, A.)2, Pedley RB (Pedley, R. B.)2, Neri D (Neri, D.)1 Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours BRITISH JOURNAL OF CANCER Volume: 101 Issue: 4 Pages: 645-657 Published: AUG 11 2009 Stock C, Schwab A Protons make tumor cells move like clockwork PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY Volume: 458 Issue: 5 Pages: 981-992 Published: SEP 2009 Ahlskog JKJ (Ahlskog, Julia K. J.)1, Dumelin CE (Dumelin, Christoph E.)2, Trussel S (Truessel, Sabrina)1, Marlind J (Marlind, Jessica)1, Neri D (Neri, Dario)1 In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Volume: 19 Issue: 16 Pages: 4851-4856 Published: AUG 15 2009 Li Y (Li, Ying)1, Wang H (Wang, Hai)1, Oosterwijk E (Oosterwijk, Egbert)3, Tu CK (Tu, Chingkuang)2, Shiverick KT (Shiverick, Kathleen T.)2, Silverman DN (Silverman, David N.)2, Frost SC (Frost, Susan C.)1 Expression and Activity of Carbonic Anhydrase IX Is Associated With Metabolic Dysfunction in MDA-MB-231 Breast Cancer Cells CANCER INVESTIGATION Volume: 27 Issue: 6 Pages: 613-623 Published: 2009 Amberger-Murphy V Hypoxia Helps Glioma to Fight Therapy CURRENT CANCER DRUG TARGETS Volume: 9 Issue: 3 Pages: 381-390 Published: MAY 2009 Abdel-Hamid MK (Abdel-Hamid, Mohammed K.)1, Abdel-Hafez AA (Abdel-Hafez, Atef A.)1, El-Koussi NA (El-Koussi, Nawal A.)1, Mahfouz NM (Mahfouz, Nadia M.)1 Quantitative structure-activity relationship (QSAR) studies on a series of 1,3,4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY Volume: 24 Issue: 3 Pages: 722-729 Published: 2009 Genis C (Genis, Caroli)1, Sippel KH (Sippel, Katherine H.)1, Case N (Case, Nicolette)1, Cao WG (Cao, Wengang)2, Avvaru BS (Avvaru, Balendu Sankara)1, Tartaglia LJ (Tartaglia, Lawrence J.)1, Govindasamy L (Govindasamy, Lakshmanan)1, Tu C (Tu, Chinpkuang)3, Agbandje-McKenna M (Agbandje-McKenna, Mavis)1, Silverman DN (Silverman, David N.)1,3, Rosser CJ (Rosser, Charles J.)2, McKenna R (McKenna, Robert Design of a Carbonic Anhydrase IX Active-Site Mimic To Screen Inhibitors for Possible Anticancer Properties BIOCHEMISTRY Volume: 48 Issue: 6 Pages: 1322-1331 Published: FEB 17 2009 Chiche J (Chiche, Johanna)1, Ilc K (Ilc, Karine)1, Laferriere J (Laferriere, Julie)1, Trottier E (Trottier, Eric)1, Dayan F (Dayan, Frederic)1, Mazure NM (Mazure, Nathalie M.)1, Brahimi-Horn MC (Brahimi-Horn, M. Christiane)1, Pouyssegur J (Pouyssegur, Jacques Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH CANCER RESEARCH Volume: 69 Issue: 1 Pages: 358-368 Published: JAN 1 2009 Esbaugh AJ, Perry SF, Gilmour KM Hypoxia-inducible carbonic anhydrase IX expression is insufficient to alleviate intracellular metabolic acidosis in the muscle of zebrafish, Danio rerio AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY Volume: 296 Issue: 1 Pages: R150-R160 Published: JAN 2009 Tostain J (Tostain, Jacques)1, Li GR (Li, Guorong)1, Gentil-Perret A (Gentil-Perret, Anne)2, Gigante M (Gigante, Marc)1 Carbonic anhydrase 9 in clear cell renal cell carcinoma: A marker for diagnosis, prognosis and treatment EUROPEAN JOURNAL OF CANCER Volume: 46 Issue: 18 Pages: 3141-3148 Published: DEC 2010 Akula NVMK (Akula, N. V. Murali Krishna)1, Kumar S (Kumar, Surendra)1, Singh V (Singh, Vineet)1, Tiwari M (Tiwari, Meena)1 Homology modeling and QSAR analysis of 1,3,4-thiadiazole and 1,3,4-triazole derivatives as carbonic anhydrase inhibitors INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS Volume: 47 Issue: 4 Pages: 234-242 Published: AUG 2010 Kallio H (Kallio, Heini)1,2,3, Hilvo M (Hilvo, Mika)4, Rodriguez A (Rodriguez, Alejandra)1,2,3, Lappalainen EH (Lappalainen, Eeva-Helena)1,2,3, Lappalainen AM (Lappalainen, Anna-Maria)1,2,3, Parkkila S (Parkkila, Seppo)1,2,3 Global transcriptional response to carbonic anhydrase IX deficiency in the mouse stomach : BMC GENOMICS Volume: 11 Article Number: 397 Published: JUN 23 2010 Chiche J (Chiche, Johanna)1, Ilc K (Ilc, Karine)1, Brahimi-Horn MC (Brahimi-Horn, M. Christiane)1, Pouyssegur J (Pouyssegur, Jacques)1 Membrane-bound carbonic anhydrases are key pH regulators controlling tumor growth and cell migration ADVANCES IN ENZYME REGULATION, VOL 50 Book Series: Advances in Enzyme Regulation Volume: 50 Pages: 20-33 Published: 2010 Bejot R (Bejot, Romain)1, Kersemans V (Kersemans, Veerle)2, Kelly C (Kelly, Catherine)2, Carroll L (Carroll, Laurence)1, King RC (King, Robert C.)1, Gouverneur V (Gouverneur, Veronique)1 Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [F-18]FMISO as hypoxia-selective tracer for PET NUCLEAR MEDICINE AND BIOLOGY Volume: 37 Issue: 5 Pages: 565-575 Published: JUL 2010 Delacruz J (Delacruz, Joannalyn)1, Mikulski R (Mikulski, Rose)1, Tu C (Tu, Chingkuang)1, Li Y (Li, Ying)2, Wang H (Wang, Hai)2, Shiverick KT (Shiverick, Kathleen T.)1, Frost SC (Frost, Susan C.)2, Horenstein NA (Horenstein, Nicole A.)3, Silverman DN (Silverman, David N.)1 Detecting extracellular carbonic anhydrase activity using membrane inlet mass spectrometry ANALYTICAL BIOCHEMISTRY Volume: 403 Issue: 1-2 Pages: 74-78 Published: AUG 2010 Dahinden C (Dahinden, Corinne)2,3, Ingold B (Ingold, Barbara)1, Wild P (Wild, Peter)1, Boysen G (Boysen, Gunther)1, Luu VD (Luu, Van-Duc)1, Montani M (Montani, Matteo)1, Kristiansen G (Kristiansen, Glen)1, Sulser T (Sulser, Tullio)4, Buhlmann P (Buehlmann, Peter)2,3, Moch H (Moch, Holger)1,3, Schraml P (Schraml, Peter)1 Mining Tissue Microarray Data to Uncover Combinations of Biomarker Expression Patterns that Improve Intermediate Staging and Grading of Clear Cell Renal Cell Cancer CLINICAL CANCER RESEARCH Volume: 16 Issue: 1 Pages: 88-98 Published: JAN 1 2010 Poulsen SA Carbonic anhydrase inhibition as a cancer therapy: a review of patent literature, 2007-2009 EXPERT OPINION ON THERAPEUTIC PATENTS Volume: 20 Issue: 6 Pages: 795-806 Published: JUN 2010 Chiche J (Chiche, Johanna)1, Brahimi-Horn MC (Brahimi-Horn, M. Christiane)1, Pouyssegur J (Pouyssegur, Jacques)1 Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Volume: 14 Issue: 4 Pages: 771-794 Published: APR 2010 Choschzick M (Choschzick, Matthias)1,2, Woelber L (Woelber, Linn)3, Hess S (Hess, Stephan)2, Eulenburg CZ (Eulenburg, Christine zu)4, Schwarz J (Schwarz, Joerg)3, Simon R (Simon, Ronald)2, Mahner S (Mahner, Sven)3, Jaenicke F (Jaenicke, Fritz)3, Muller V (Muller, Volkmar)3 Overexpression of carbonic anhydrase IX (CAIX) in vulvar cancer is associated with tumor progression and development of locoregional lymph node metastases VIRCHOWS ARCHIV Volume: 456 Issue: 5 Pages: 483-490 Published: MAY 2010 Mees G (Mees, Gilles)7, Vangestel C (Vangestel, Christel)4, Dierckx R (Dierckx, Rudi)1,2,3,7, Pauwels P (Pauwels, Patrick)5, Van Meerbeeck J (Van Meerbeeck, Jan)6, Van de wiele C (Van de Wiele, Christophe)1,2,3,7 Carbonic Anhydrase IX Expression Correlates with FDG Uptake by Primary Non-Small Cell Lung Cancer CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS Volume: 25 Issue: 2 Pages: 149-154 Published: APR 2010 Xu C (Xu, Chen)1,4, Lo A (Lo, Agnes)1,4, Yammanuru A (Yammanuru, Anuradha)1, Tallarico ASC (Tallarico, Aimee St. Clair)1, Brady K (Brady, Kristen)1, Murakami A (Murakami, Akikazu)1, Barteneva N (Barteneva, Natasha)2,3,5, Zhu Q (Zhu, Quan)1,4, Marasco WA (Marasco, Wayne A.)1,4 Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology PLOS ONE Volume: 5 Issue: 3 Article Number: e9625 Published: MAR 10 2010 Dahinden, C.a b , Ingold, B.c e , Wild, P.c , Boysen, G.c , Luu, V.-D.c , Montani, M.c , Kristiansen, G.c , Sulser, T.d , Bühlmann, P.a b , Moch, H.b c , Schraml, P. Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer Clinical Cancer Research 16 (1), pp. 88-98 , 2010 Ortutay, C (Ortutay, Csaba)1; Olatubosun, A (Olatubosun, Ayodeji)1; Parkkila, S (Parkkila, Seppo)1,2; Vihinen, M (Vihinen, Mauno)1,2; Tolvanen, M (Tolvanen, Martti)1 Editor(s): Berhardt, LV An Evolutionary Analysis of Insect Carbonic Anhydrases ADVANCES IN MEDICINE AND BIOLOGY, VOL 7 Book Series: Advances in Medicine and Biology Volume: 7 Pages: 145-168 Published: 2010 Cobanoglu, U (Cobanoglu, Ufuk)3; Demir, H (Demir, Halit)1; Duran, M (Duran, Memet)2; Sehitogullari, A (Sehitogullari, Abidin)3; Mergan, D (Mergan, Duygu)3; Demir, C (Demir, Canan) Erythrocyte Catalase and Carbonic Anhydrase Activities in Lung ASIAN PACIFIC JOURNAL OF CANCER PREVENTION Volume: 11 Issue: 5 Pages: 1377-1382 Published: 2010 Fingleton, B (Fingleton, Barbara)1; Lynch, C (Lynch, Conor)1,2 Editor(s): Zent, R; Pozzi, A Cancer in Context: Importance of the Tumor Microenvironment CELL-EXTRACELLULAR MATRIX INTERACTIONS IN CANCER Pages: 43-63 DOI: 10.1007/978-1-4419-0814-8_3 Published: 2010 Said, HM (Said, Harun M.)1; Hagemann, C (Hagemann, Carsten)2; Staab, A (Staab, Adrian)1,6,7; Polat, B (Polat, Buelent)1; Guckenberger, M (Guckenberger, Mathias)1; Anacker, J (Anacker, Jelena)2,3; Flentje, M (Flentje, Michael)1; Vordermark, D (Vordermark, Dirk)1,4 Editor(s): Gutierrez, LM BRAIN CANCER ASSOCIATED TUMOR MARKER GENES EXPRESSION PATTERN IN HUMANS NEURO-ONCOLOGY AND CANCER TARGETED THERAPY Book Series: Cancer Etiology Diagnosis and Treatments Pages: 65-98 Published: 2010 Swietach Pawel; Harris Adrian L.; Vaughan-Jones Richard D. The Tumor Microenvironment: New Insights into Regulation of Tumor pH by Carbonic Anhydrases TUMOR MICROENVIRONMENT Book Series: Cancer Drug Discovery and Development Pages: 23-41 DOI: 10.1007/978-1-4419-6615-5_2 Published: 2010 Li, JB (Li, Jianbo)1,2; Shi, LL (Shi, Lingli)1,2; Wang, C (Wang, Cheng)1,2; Zhang, XH (Zhang, Xiaohui)1,2; Jia, LN (Jia, Lina)1,2; Li, X (Li, Xiao)1,2; Zhou, W (Zhou, Wei)1; Qi, YJ (Qi, Yujin)1; Zhang, L (Zhang, Lan)1 Preliminary biological evaluation of (125)I-labeled anti-carbonic anhydrase IX monoclonal antibody in the mice bearing HT-29 tumors NUCLEAR MEDICINE COMMUNICATIONS Volume: 32 Issue: 12 Pages: 1190-1193 DOI: 10.1097/MNM.0b013e32834bf3e1 Published: DEC 2011 Lecoeur, M (Lecoeur, Marie)1; Goossens, JF (Goossens, Jean-Francois)1; Vaccher, C (Vaccher, Claude)1; Bonte, JP (Bonte, Jean-Paul)1; Foulon, C (Foulon, Catherine)1 A multivariate approach for the determination of isoelectric point of human carbonic anhydrase isoforms by capillary isoelectric focusing ELECTROPHORESIS Volume: 32 Issue: 20 Special Issue: SI Pages: 2857-2866 DOI: 10.1002/elps.201100219 Published: OCT 2011 Chen, J (Chen, Jun)2,4; Qiu, XZ (Qiu, Xiaozhong)7; Ouyang, J (Ouyang, Jun)7; Kong, JM (Kong, Jiming)6; Zhong, W (Zhong, Wen)1,5; Xing, MMQ (Xing, Malcolm M. Q.)2,3,4,7 pH and Reduction Dual-Sensitive Copolymeric Micelles for Intracellular Doxorubicin Delivery BIOMACROMOLECULES Volume: 12 Issue: 10 Pages: 3601-3611 DOI: 10.1021/bm200804j Published: OCT 2011 Proescholdt, M (Proescholdt, Martin)1; Merrill, M (Merrill, Marsha)3; Stoerr, EM (Stoerr, Eva-Maria)1; Lohmeier, A (Lohmeier, Annette)1; Dietmaier, W (Dietmaier, Wolfgang)2; Brawanski, A (Brawanski, Alexander)1 Expression of carbonic anhydrase IX in craniopharyngiomas Laboratory investigation JOURNAL OF NEUROSURGERY Volume: 115 Issue: 4 Pages: 796-801 DOI: 10.3171/2011.6.JNS1168 Published: OCT 2011 El-Sayed, N.S., El-Bendary, E.R., El-Ashry, S.M., El-Kerdawy, M.M. Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2-a]pyrimidines European Journal of Medicinal Chemistry 46 (9) , pp. 3714-3720 , 2011 Langhammer, S (Langhammer, Stefan)1; Najjar, M (Najjar, Maher)2; Hess-Stumpp, H (Hess-Stumpp, Holger)2; Thierauch, KH (Thierauch, Karl-Heinz)2 LDH-A influences hypoxia-inducible factor 1 alpha (HIF1 alpha) and is critical for growth of HT29 colon carcinoma cells in vivo TARGETED ONCOLOGY Volume: 6 Issue: 3 Pages: 155-162 DOI: 10.1007/s11523-011-0184-7 Published: SEP 2011 Zhang, S., Yang, C., Lu, W., Huang, J., Zhu, W., Li, H., Xu, Y., Qian, X. A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging Chemical Communications 47 (29) , pp. 8301-8303 , 2011 Hashim, A.I., Zhang, X., Wojtkowiak, J.W., Martinez, G.V., Gillies, R.J. Imaging pH and metastasis NMR in Biomedicine 24 (6) , pp. 582-591,2011 Li, Y., Tu, C., Wang, H., Silverman, D.N., Frost, S.C. Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cells Journal of Biological Chemistry 286 (18) , pp. 15789-15796 , 2011 Ilie, MI (Ilie, Marius I.)1,2,3; Hofman, V (Hofman, Veronique)1,2,3,4; Ortholan, C (Ortholan, Cecile)3,5; El Ammadi, R (El Ammadi, Reda)3,6; Bonnetaud, C (Bonnetaud, Christelle)4; Havet, K (Havet, Katia)1; Venissac, N (Venissac, Nicolas)1,3,7; Mouroux, J (Mouroux, Jerome)1,3,7; Mazure, NM (Mazure, Nathalie M.)3,8,9; Pouyssegur, J (Pouyssegur, Jacques)3,8,9; Hofman, P (Hofman, Paul)1,2,3,4 Overexpression of carbonic anhydrase XII in tissues from resectable non-small cell lung cancers is a biomarker of good prognosis INTERNATIONAL JOURNAL OF CANCER Volume: 128 Issue: 7 Pages: 1614-1623 DOI: 10.1002/ijc.25491 Published: APR 1 2011 Stander Andre; Joubert Fourie; Joubert Annie Docking, Synthesis, and in vitro Evaluation of Antimitotic Estrone Analogs CHEMICAL BIOLOGY & DRUG DESIGN Volume: 77 Issue: 3 Pages: 173-181 DOI: 10.1111/j.1747-0285.2010.01064.x Published: MAR 2011 Parks Scott K.; Chiche Johanna; Pouyssegur Jacques pH Control Mechanisms of Tumor Survival and Growth JOURNAL OF CELLULAR PHYSIOLOGY Volume: 226 Issue: 2 Pages: 299-308 DOI: 10.1002/jcp.22400 Published: FEB 2011 Nakamura, J., Kitajima, Y., Kai, K., Hashiguchi, K., Hiraki, M., Noshiro, H., Miyazaki, K. Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer American Journal of Pathology 178 (2) , pp. 515-524 , 2011 Steffan, J.J., Coleman, D.T., Cardelli, J.A. The HGF-Met signaling axis: Emerging themes and targets of inhibition Current Protein and Peptide Science 12 (1) , pp. 12-22 ,2011 Woelber, L (Woelber, Linn)1; Kress, K (Kress, Kerstin)1; Kersten, JF (Kersten, Jan F.)2; Choschzick, M (Choschzick, Matthias)3; Kilic, E (Kilic, Ergin)3; Herwig, U (Herwig, Uwe)4; Lindner, C (Lindner, Christoph)5; Schwarz, J (Schwarz, Joerg)1,6; Jaenicke, F (Jaenicke, Fritz)1; Mahner, S (Mahner, Sven)1; Milde-Langosch, K (Milde-Langosch, Karin)1; Mueller, V (Mueller, Volkmar)1; Ihnen, M (Ihnen, Maike)1 Carbonic anhydrase IX in tumor tissue and sera of patients with primary cervical cancer BMC CANCER Volume: 11 Article Number: 12 DOI: 10.1186/1471-2407-11-12 Published: JAN 11 2011 Zhang, SY (Zhang, Shenyi)1; Yang, CM (Yang, Chunmei)1; Lu, WQ (Lu, Weiqiang)1; Huang, J (Huang, Jin)1; Zhu, WP (Zhu, Weiping)1; Li, HL (Li, Honglin)1; Xu, YF (Xu, Yufang)1; Qian, XH (Qian, Xuhong)1 A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging CHEMICAL COMMUNICATIONS Volume: 47 Issue: 29 Pages: 8301-8303 DOI: 10.1039/c1cc12386f Published: 2011 Li, Y (Li, Ying)1; Wang, H (Wang, Hai)1; Tu, CK (Tu, Chingkuang)2; Shiverick, KT (Shiverick, Kathleen T.)2; Silverman, DN (Silverman, David N.)2; Frost, SC (Frost, Susan C.)1 Role of hypoxia and EGF on expression, activity, localization and phosphorylation of carbonic anhydrase IX in MDA-MB-231 breast cancer cells BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH Volume: 1813 Issue: 1 Pages: 159-167 DOI: 10.1016/j.bbamcr.2010.09.018 Published: JAN 2011 Husain, Asif; Madhesia, Diwakar Heterocyclic compounds as carbonic anhydrase inhibitor JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY Volume: 27 Issue: 6 Pages: 773-783 DOI: 10.3109/14756366.2011.617882 Published: DEC 2012 Proescholdt, MA (Proescholdt, Martin A.)[ 1 ] ; Merrill, MJ (Merrill, Marsha J.)[ 2 ] ; Stoerr, EM (Stoerr, Eva-Maria)[ 1 ] ; Lohmeier, A (Lohmeier, Annette)[ 1 ] ; Pohl, F (Pohl, Fabian)[ 3 ] ; Brawanski, A (Brawanski, Alexander)[ Function of carbonic anhydrase IX in glioblastoma multiforme NEURO-ONCOLOGY Volume: 14 Issue: 11 Pages: 1357-1366 DOI: 10.1093/neuonc/nos216 Published: NOV 2012 Tian, Li; Bae, You Han Cancer nanomedicines targeting tumor extracellular pH COLLOIDS AND SURFACES B-BIOINTERFACES Volume: 99 Special Issue: SI Pages: 116-126 DOI: 10.1016/j.colsurfb.2011.10.039 Published: NOV 1 2012 Mizusawa, K (Mizusawa, Keigo)[ 1 ] ; Takaoka, Y (Takaoka, Yousuke)[ 1 ] ; Hamachi, I (Hamachi, Itaru)[ 1,2 ] Specific Cell Surface Protein Imaging by Extended Self-Assembling Fluorescent Turn-on Nanoprobes JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 134 Issue: 32 Pages: 13386-13395 DOI: 10.1021/ja304239g Published: AUG 15 2012 Aggarwal, M., McKenna, R. Update on carbonic anhydrase inhibitors: A patent review (2008 - 2011) Expert Opinion on Therapeutic Patents 22 (8) , pp. 903-915 , 2012 Boleij, Annemarie; Tjalsma, Harold Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer BIOLOGICAL REVIEWS Volume: 87 Issue: 3 Pages: 701-730 DOI: 10.1111/j.1469-185X.2012.00218.x Published: AUG 2012 Singh, S. A QSAR study on novel series of carbonic anhydrase inhibitors hCA IX-tumor-associated (hypoxia) Medicinal Chemistry 8 (4) , pp. 656-672 , 2012 Kim, BR (Kim, Boh-Ram)[ 1 ] ; Shin, HJ (Shin, Hye-Jin)[ 1 ] ; Kim, JY (Kim, Joo-Young)[ 1 ] ; Byun, HJ (Byun, Hyun-Jung)[ 1 ] ; Lee, JH (Lee, Jeong Heon)[ 2 ] ; Sung, YK (Sung, Young Kwan)[ 3 ] ; Rho, SB (Rho, Seung Bae)[ 1 ] Dickkopf-1 (DKK-1) interrupts FAK/PI3K/mTOR pathway by interaction of carbonic anhydrase IX (CA9) in tumorigenesis CELLULAR SIGNALLING Volume: 24 Issue: 7 Pages: 1406-1413 DOI: 10.1016/j.cellsig.2012.03.002 Published: JUL 2012 Singh, Shalini In Silico Modeling of Carbonic Anhydrase Inhibitor hCA IX-Tumor Associated (Hypoxia) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES Volume: 82 Issue: 2 Pages: 113-123 DOI: 10.1007/s40010-012-0018-8 Published: JUN 2012 Aureli, M (Aureli, Massimo)[ 1 ] ; Loberto, N (Loberto, Nicoletta)[ 1 ] ; Bassi, R (Bassi, Rosaria)[ 1 ] ; Ferraretto, A (Ferraretto, Anita)[ 1 ] ; Perego, S (Perego, Silvia)[ 1 ] ; Lanteri, P (Lanteri, Patrizia)[ 1 ] ; Chigorno, V (Chigorno, Vanna)[ 1 ] ; Sonnino, S (Sonnino, Sandro)[ 1 ] ; Prinetti, A (Prinetti, Alessandro)[ 1 ] Plasma Membrane-Associated Glycohydrolases Activation by Extracellular Acidification due to Proton Exchangers NEUROCHEMICAL RESEARCH Volume: 37 Issue: 6 Special Issue: SI Pages: 1296-1307 DOI: 10.1007/s11064-012-0725-1 Published: JUN 2012 Chien, MH (Chien, Ming-Hsien)[ 3 ] ; Ying, TH (Ying, Tsung-Ho)[ 4,5 ] ; Hsieh, YH (Hsieh, Yi-Hsien)[ 6 ] ; Lin, CH (Lin, Chien-Huang)[ 7 ] ; Shih, CH (Shih, Chun-Han)[ 2 ] ; Wei, LH (Wei, Lin-Hung)[ 8 ] ; Yang, SF (Yang, Shun-Fa)[ 1,9 ] Tumor-associated carbonic anhydrase XII is linked to the growth of primary oral squamous cell carcinoma and its poor prognosis ORAL ONCOLOGY Volume: 48 Issue: 5 Pages: 417-423 DOI: 10.1016/j.oraloncology.2011.11.015 Published: MAY 2012 Mariani, V (Mariani, Valentina)[ 1 ] ; Ponti, J (Ponti, Jessica)[ 1 ] ; Giudetti, G (Giudetti, Guido)[ 1 ] ; Broggi, F (Broggi, Francesca)[ 1 ] ; Marmorato, P (Marmorato, Patrick)[ 1 ] ; Gioria, S (Gioria, Sabrina)[ 1 ] ; Franchini, F (Franchini, Fabio)[ 1 ] ; Rauscher, H (Rauscher, Hubert)[ 1 ] ; Rossi, F (Rossi, Francois)[ 1 ] Online monitoring of cell metabolism to assess the toxicity of nanoparticles: The case of cobalt ferrite NANOTOXICOLOGY Volume: 6 Issue: 3 Pages: 272-287 DOI: 10.3109/17435390.2011.572302 Published: MAY 2012 Betof, AS (Betof, A. S.)[ 1 ] ; Rabbani, ZN (Rabbani, Z. N.)[ 2 ] ; Hardee, ME (Hardee, M. E.)[ 1 ] ; Kim, SJ (Kim, S. J.)[ 3 ] ; Broadwater, G (Broadwater, G.)[ 4 ] ; Bentley, RC (Bentley, R. C.)[ 1 ] ; Snyder, SA (Snyder, S. A.)[ 2 ] ; Vujaskovic, Z (Vujaskovic, Z.)[ 2 ] ; Oosterwijk, E (Oosterwijk, E.)[ 5 ] ; Harris, LN (Harris, L. N.)[ 6 ] ; Horton, JK (Horton, J. K.)[ 2 ] ; Dewhirst, MW (Dewhirst, M. W.)[ 1,2 ] ; Blackwell, KL (Blackwell, K. L.)[ 2,7 ] Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification BRITISH JOURNAL OF CANCER Volume: 106 Issue: 5 Pages: 916-922 DOI: 10.1038/bjc.2012.32 Published: FEB 28 2012 Pinheiro, C (Pinheiro, Celine)[ 1,2 ] ; Longatto, A (Longatto-Filho, Adhemar)[ 1,2,3 ] ; Azevedo-Silva, J (Azevedo-Silva, Joao)[ 4 ] ; Casal, M (Casal, Margarida)[ 4 ] ; Schmitt, FC (Schmitt, Fernando C.)[ 5,6 ] ; Baltazar, F (Baltazar, Fatima)[ 1,2 ] Role of monocarboxylate transporters in human cancers: state of the art JOURNAL OF BIOENERGETICS AND BIOMEMBRANES Volume: 44 Issue: 1 Pages: 127-139 DOI: 10.1007/s10863-012-9428-1 Published: FEB 2012 Li, J., Shen, H., Niu, T., Zhang, X., Qi, Y., Zhang Radiolabeling of anti-carbonic anhydrase IX monoclonal antibody by 99Tc m and its imaging in the mouse bearing tumors He Jishu/Nuclear Techniques 35 (7) , pp. 535-538, 2012 Kawai, Y (Kawai, Yoshiko)[ 1 ] ; Kaidoh, M (Kaidoh, Maki)[ 1 ] ; Yokoyama, Y (Yokoyama, Yumiko)[ 1 ] ; Ohhashi, T Cell surface F-1/F-o ATP synthase contributes to interstitial flow-mediated development of the acidic microenvironment in tumor tissues AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY Volume: 305 Issue: 11 Pages: C1139-C1150, 2013 Larkin, Spencer; Kyprianou, Natasha Molecular Signatures in Urologic Tumors INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 14 Issue: 9 Pages: 18421-18436 Published: SEP 2013 Parks, Scott K.; Chiche, Johanna; Pouyssegur, Jacques Disrupting proton dynamics and energy metabolism for cancer therapy NATURE REVIEWS CANCER Volume: 13 Issue: 9 Pages: 611-623 Published: SEP 2013 Wang, ZC (Wang, Zhong-Chang)[ 1 ] ; Qin, YJ (Qin, Ya-Juan)[ 1 ] ; Wang, PF (Wang, Peng-Fei)[ 1 ] ; Yang, YA (Yang, Yong-An)[ 1 ] ; Wen, Q (Wen, Qing)[ 1 ] ; Zhang, X (Zhang, Xin)[ 1 ] ; Qiu, HY (Qiu, Han-Yue)[ 1 ] ; Duan, YT (Duan, Yong-Tao)[ 1 ] ; Wang, YT (Wang, Yan-Ting)[ 1 ] ; Sang, YL (Sang, Ya-Li)[ 1 ] ; Zhu, HL Sulfonamides containing coumarin moieties selectively and potently inhibit carbonic anhydrases II and IX: Design, synthesis, inhibitory activity and 3D-QSAR analysis EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY Volume: 66 Pages: 1-11 , 2013 Suthar, SK (Suthar, Sharad Kumar)[ 1 ] ; Bansal, S (Bansal, Sumit)[ 1 ] ; Lohan, S (Lohan, Sandeep)[ 1 ] ; Modak, V (Modak, Vikarm)[ 2 ] ; Chaudhary, A (Chaudhary, Anil)[ 3 ] ; Tiwari, A Design and synthesis of novel 4-(4-oxo-2-arylthiazolidin-3-yl) benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY Volume: 66 Pages: 372-379, 2013 Guo Yingjun; Qu Xun cid-sensing ion channels under hypoxia CHANNELS Volume: 7 Issue: 4 Pages: 231-237 Published: JUL 1 2013 Wang, LY (Wang, Liyan)[ 1 ] ; Yang, CM (Yang, Chunmei)[ 1 ] ; Lu, WQ (Lu, Weiqiang)[ 1 ] ; Liu, L (Liu, Li)[ 1 ] ; Gao, R (Gao, Rui)[ 1 ] ; Liao, S (Liao, Sha)[ 1 ] ; Zhao, ZJ (Zhao, Zhenjiang)[ 1 ] ; Zhu, LL (Zhu, Lili)[ 1 ] ; Xu, YF (Xu, Yufang)[ 1 ] ; Li, HL (Li, Honglin)[ 1 ] ; Huang, J (Huang, Jin)[ 1 ] ; Zhu, WP Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Volume: 23 Issue: 12 Pages: 3496-3499, 2013 Gary-Bobo, M (Gary-Bobo, M.)[ 1,4 ] ; Vaillant, O (Vaillant, O.)[ 1 ] ; Maynadier, M (Maynadier, M.)[ 1 ] ; Basile, I (Basile, I.)[ 1 ] ; Gallud, A (Gallud, A.)[ 1 ] ; El Cheikh, K (El Cheikh, K.)[ 1 ] ; Bouffard, E (Bouffard, E.)[ 1 ] ; Morere, A (Morere, A.)[ 1,4 ] ; Rebillard, X (Rebillard, X.)[ 1,2 ] ; Puche, P (Puche, P.)[ 1,3 ] ; Nirde, P (Nirde, P.)[ 1 ] ; Garcia, M Targeting Multiplicity: The Key Factor for Anti-Cancer Nanoparticles CURRENT MEDICINAL CHEMISTRY Volume: 20 Issue: 15 Pages: 1946-1955, 2013 Sun, WQ (Sun Wei-Qi)[ 1 ] ; Zhang, JL (Zhang Ji-Long)[ 2 ] ; Zheng, QC (Zheng Qing-Chuan)[ 2 ] ; Sun, ZW (Sun Zhi-Wei)[ 1,3 ] ; Zhang, HX Molecular Dynamics Simulations of the Unbinding of Phenylsulfonamide from Carbonic Anhydrase II ACTA PHYSICO-CHIMICA SINICA Volume: 29 Issue: 4 Pages: 843-848, 2013 Wrann, S (Wrann, Simon)[ 1,2 ] ; Kaufmann, MR (Kaufmann, Muriel R.)[ 1,2 ] ; Wirthner, R (Wirthner, Renato)[ 1,2 ] ; Stiehl, DP (Stiehl, Daniel P.)[ 1,2 ] ; Wenger, RH HIF mediated and DNA damage independent histone H2AX phosphorylation in chronic hypoxia IOLOGICAL CHEMISTRY Volume: 394 Issue: 4 Pages: 519-528, 2013 Gieling, RG (Gieling, Roben G.)[ 1 ] ; Parker, CA (Parker, Catriona A.)[ 2 ] ; De Costa, LA (De Costa, Lisa A.)[ 2 ] ; Robertson, N (Robertson, Naomi)[ 3 ] ; Harris, AL (Harris, Adrian L.)[ 3 ] ; Stratford, IJ (Stratford, Ian J.)[ 2 ] ; Williams, KJ Inhibition of carbonic anhydrase activity modifies the toxicity of doxorubicin and melphalan in tumour cells in vitro JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY Volume: 28 Issue: 2 Pages: 360-369, 2013 Aggarwal, Mayank; Kondeti, Bhargav; McKenna, Robert Insights towards sulfonamide drug specificity in alpha-carbonic anhydrases BIOORGANIC & MEDICINAL CHEMISTRY Volume: 21 Issue: 6 Pages: 1526-1533 Published: MAR 15 2013 Dolan, C (Dolan, Ciaran)[ 1 ] ; Moriarty, RD (Moriarty, Roisin D.)[ 1 ] ; Lestini, E (Lestini, Elena)[ 1 ] ; Devocelle, M (Devocelle, Marc)[ 2 ] ; Forster, RJ (Forster, Robert J.)[ 1 ] ; Keyes, TE Cell uptake and cytotoxicity of a novel cyclometalated iridium(III) complex and its octaarginine peptide conjugate JOURNAL OF INORGANIC BIOCHEMISTRY Volume: 119 Pages: 65-74, 2013 Said, Harun M. Determination Human Brain Tumor Marker Gene Carbonic Anhydrase 9 (CA9) Gene Expression in Different type of Brain Tumor Cells Book Group Author(s): IEEE Conference: ICME International Conference on Complex Medical Engineering (CME) Location: Beijing, PEOPLES R CHINA Date: MAY 25-28, 2013 2013 ICME INTERNATIONAL CONFERENCE ON COMPLEX MEDICAL ENGINEERING (CME) Pages: 403-407 Published: 2013 Navratilova, J (Navratilova, Jarmila)[ 1 ] ; Hankeova, T (Hankeova, Tereza)[ 1 ] ; Benes, P (Benes, Petr)[ 1,2 ] ; Smarda, J Acidic pH of Tumor Microenvironment Enhances Cytotoxicity of the Disulfiram/Cu2+ Complex to Breast and Colon Cancer Cells CHEMOTHERAPY olume: 59 Issue: 2 Pages: 112-120, 2013 Tian, Y (Tian, Ye)[ 1,2,3 ] ; Glogowska, A (Glogowska, Aleksandra)[ 4 ] ; Zhong, W (Zhong, Wen)[ 5,6 ] ; Klonisch, T (Klonisch, Thomas)[ 2,4,6,7 ] ; Xing, M Polymeric mesoporous silica nanoparticles as a pH-responsive switch to control doxorubicin intracellular delivery JOURNAL OF MATERIALS CHEMISTRY B Volume: 1 Issue: 39 Pages: 5264-5272, 2013 Doyen, J.ab, Parks, S.K.a, Marcié, S.b, Pouysségur, J.ac, Chiche, J. Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis Frontiers in Oncology Volume 2 JAN, 2013, Article number Article 00199 Guo, J.ab, Li, F.-R.ab, Liu, Y.ab, Cheng, M.-S. Progress in the study of carbonic anhydrase inhibitors as potential anticancer drugs Yaoxue Xuebao Volume 48, Issue 11, 12 November 2013, Pages 1637-1643 Bevensee, M.O.a, Boron, W.F. Control of Intracellular pH Seldin and Geibisch's The Kidney Volume 2, 2013, Pages 1773-1835 Yingjun, G., Xun, Q. Acid-sensing ion channels under hypoxia Channels Volume 7, Issue 4, July 2013, Pages 231-237 Wei, H., Zhuo, R.-X., Zhang, X.-Z. Design and development of polymeric micelles with cleavable links for intracellular drug delivery Progress in Polymer Science Volume 38, Issue 3-4, March 2013, Pages 503-535 Itakura, S (Itakura, Shoko)[ 1 ] ; Hama, S (Hama, Susumu)[ 1 ] ; Ohgita, T (Ohgita, Takashi)[ 1 ] ; Kogure, K Development of Nanoparticles Incorporating a Novel Liposomal Membrane Destabilization Peptide for Efficient Release of Cargos into Cancer Cells PLOS ONE Volume: 9 Issue: 10, 2014 Lau, J (Lau, Joseph)[ 1 ] ; Pan, JH (Pan, Jinhe)[ 1 ] ; Zhang, ZX (Zhang, Zhengxing)[ 1 ] ; Hundal-Jabal, N (Hundal-Jabal, Navjit)[ 1 ] ; Liu, ZB (Liu, Zhibo)[ 2 ] ; Benard, F (Benard, Francois)[ 1 ] ; Lin, KS Synthesis and evaluation of F-18-labeled tertiary benzenesulfonamides for imaging carbonic anhydrase IX expression in tumours with positron emission tomography BIOORGANIC & MEDICINAL CHEMISTRY LETTERS olume: 24 Issue: 14 Pages: 3064-3068, 2014 Zheng, Qiaoli; Ye, Jingjia; Cao, Jiang Translational regulator eIF2 alpha in tumor TUMOR BIOLOGY Volume: 35 Issue: 7 Pages: 6255-6264 Published: JUL 2014 Aomatsu, N (Aomatsu, Naoki)[ 1 ] ; Yashiro, M (Yashiro, Masakazu)[ 1,2 ] ; Kashiwagi, S (Kashiwagi, Shinichiro)[ 1 ] ; Kawajiri, H (Kawajiri, Hidemi)[ 1 ] ; Takashima, T (Takashima, Tsutomu)[ 1 ] ; Ohsawa, M (Ohsawa, Masahiko)[ 3 ] ; Wakasa, K (Wakasa, Kenichi)[ 3 ] ; Hirakawa, K Carbonic anhydrase 9 is associated with chemosensitivity and prognosis in breast cancer patients treated with taxane and anthracycline BMC CANCER Volume: 14, Article Number: 400 2014 Chhajed, M (Chhajed, Mahavir)[ 1 ] ; Shrivastava, AK (Shrivastava, Anil Kumar)[ 2 ] ; Taile, V Synthesis of 5-arylidine amino-1,3,4-thiadiazol-2-[(N-substituted benzyol)]sulphonamides endowed with potent antioxidants and anticancer activity induces growth inhibition in HEK293, BT474 and NCI-H226 cells MEDICINAL CHEMISTRY RESEARCH Volume: 23 Issue: 6 Pages: 3049-3064, 2014 Cuninghame, S (Cuninghame, Sean)[ 2,1 ] ; Jackson, R (Jackson, Robert)[ 2,1 ] ; Zehbe, I Hypoxia-inducible factor 1 and its role in viral carcinogenesis VIROLOGY Volume: 456 Pages: 370-383, 2014 Perez, C (Perez, Carlos)[ 1,2 ] ; Diaz-Garcia, CV (Vanesa Diaz-Garcia, C.)[ 1,2 ] ; Agudo-Lopez, A (Agudo-Lopez, Alba)[ 1,2 ] ; del Solar, V (del Solar, Virginia)[ 3 ] ; Cabrera, S (Cabrera, Silvia)[ 3 ] ; Agullo-Ortuno, MT (Teresa Agullo-Ortuno, M.)[ 1,2 ] ; Navarro-Ranninger, C (Navarro-Ranninger, Carmen)[ 3 ] ; Aleman, J (Aleman, Jose)[ 4 ] ; Lopez-Martin, JA Evaluation of novel trans-sulfonamide platinum complexes against tumor cell lines EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY Volume: 76 Pages: 360-368, 2014 Goodwin, J (Goodwin, Jonathan)[ 1,2 ] ; Yachi, K (Yachi, Katsuya)[ 3 ] ; Nagane, M (Nagane, Masaki)[ 4 ] ; Yasui, H (Yasui, Hironobu)[ 4 ] ; Miyake, Y (Miyake, Yusuke)[ 3 ] ; Inanami, O (Inanami, Osamu)[ 4 ] ; Bobko, AA (Bobko, Andrey A.)[ 5 ] ; Khramtsov, VV (Khramtsov, Valery V.)[ 5 ] ; Hirata, H In vivo tumour extracellular pH monitoring using electron paramagnetic resonance: the effect of X- ray irradiation NMR IN BIOMEDICINE Volume: 27 Issue: 4 Pages: 453-458, 2014 Swietach, P (Swietach, Pawel)[ 1 ] ; Vaughan-Jones, RD (Vaughan-Jones, Richard D.)[ 1 ] ; Harris, AL (Harris, Adrian L.)[ 2 ] ; Hulikova, A The chemistry, physiology and pathology of pH in cancer PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES Volume: 369 Issue: 1638 Special Issue: SI Article Number: 20130099, 2014 Pearson, RM (Pearson, Ryan M.)[ 1 ] ; Hsu, HJ (Hsu, Hao-jui)[ 1 ] ; Bugno, J (Bugno, Jason)[ 1 ] ; Hong, S Understanding nano-bio interactions to improve nanocarriers for drug delivery MRS BULLETIN Volume: 39 Issue: 3 Pages: 227-237 , 2014 Kwon, SG (Kwon, Soon-Gu)[ 1,2 ] ; Roh, DH (Roh, Dae-Hyun)[ 3 ] ; Yoon, SY (Yoon, Seo-Yeon)[ 4 ] ; Moon, JY (Moon, Ji-Young)[ 1,2 ] ; Choi, SR (Choi, Sheu-Ran)[ 1,2 ] ; Choi, HS (Choi, Hoon-Seong)[ 1,2 ] ; Kang, SY (Kang, Suk-Yun)[ 5 ] ; Han, HJ (Han, Ho-Jae)[ 1,2 ] ; Beitz, AJ (Beitz, Alvin J.)[ 6 ] ; Oh, SB (Oh, Seog Bae)[ 7,8 ] ; Lee, JH Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain MOLECULAR PAIN Volume: 10, Article Number: 2, 2014 Sung, FL (Sung, Fion L.)[ 1 ] ; Cui, Y (Cui, Yan)[ 1 ] ; Hui, EP (Hui, Edwin P.)[ 1 ] ; Li, LL (Li, Lili)[ 1 ] ; Loh, TKS (Loh, Thomas K. S.)[ 2 ] ; Tao, Q (Tao, Qian)[ 1 ] ; Chan, ATC Silencing of hypoxia-inducible tumor suppressor lysyl oxidase gene by promoter methylation activates carbonic anhydrase IX in nasopharyngeal carcinoma AMERICAN JOURNAL OF CANCER RESEARCH Volume: 4 Issue: 6 Pages: 789-800, 2014 Shi, JB (Shi, Junbin)[ 1,2,3 ] ; Guobao, W (Guobao, Wang)[ 4 ] ; Chen, HL (Chen, Hongli)[ 5 ] ; Zhong, W (Zhong, Wen)[ 3 ] ; Qiu, XZ (Qiu, Xiaozhong)[ 7 ] ; Xing, MMQ Schiff based injectable hydrogel for in situ pH-triggered delivery of doxorubicin for breast tumor treatment POLYMER CHEMISTRY Volume: 5 Issue: 21 Pages: 6180-6189 , 2014 Wang, ZC (Wang, Zhong-Chang)[ 1 ] ; Duan, YT (Duan, Yong-Tao)[ 1 ] ; Qiu, HY (Qiu, Han-Yue)[ 1 ] ; Huang, WY (Huang, Wan-Yun)[ 1,2 ] ; Wang, PF (Wang, Peng-Fei)[ 1 ] ; Yan, XQ (Yan, Xiao-Qiang)[ 1 ] ; Zhang, SF (Zhang, Shu-Feng)[ 1,3 ] ; Zhu, HL Novel metronidazole-sulfonamide derivatives as potent and selective carbonic anhydrase inhibitors: design, synthesis and biology analysis RSC ADVANCES Volume: 4 Issue: 62 Pages: 33029-33038, 2014 Sang, Y (Sang, Yi)[ 1 ] ; Wang, L (Wang, Li)[ 1 ] ; Tang, JJ (Tang, Jian-Jun)[ 1 ] ; Zhang, MF (Zhang, Mei-Fang)[ 1 ] ; Zhang, MX (Zhang, Meng-Xia)[ 1 ] ; Liu, X (Liu, Xia)[ 1 ] ; Zhang, RH (Zhang, Ru-Hua)[ 1 ] ; Kang, TB (Kang, Tie-Bang)[ 1 ] ; Chen, MY Oncogenic roles of carbonic anhydrase IX in human nasopharyngeal carcinoma INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY Volume: 7 Issue: 6 Pages: 2942-2949, 2014 Frost, Susan C Physiological Functions of the Alpha Class of Carbonic Anhydrases Edited by: Frost, SC; McKenna, R CARBONIC ANHYDRASE: MECHANISM, REGULATION, LINKS TO DISEASE, AND INDUSTRIAL APPLICATIONS Book Series: Subcellular Biochemistry Volume: 75 Pages: 9-30 Published: 2014 Tafreshi, NK (Tafreshi, Narges K.)[ 1 ] ; Lloyd, MC (Lloyd, Mark C.)[ 2 ] ; Bui, MM (Bui, Marilyn M.)[ 2,3 ] ; Gillies, RJ (Gillies, Robert J.)[ 1 ] ; Morse, DL Edited by:Frost, SC; McKenna, R CARBONIC ANHYDRASE: MECHANISM, REGULATION, LINKS TO DISEASE, AND INDUSTRIAL APPLICATIONS ook Series: Subcellular Biochemistry Volume: 75 Pages: 221-254, 2014 Araste, F (Araste, Fatemeh)[ 1 ] ; Ebrahimizadeh, W (Ebrahimizadeh, Walead)[ 1 ] ; Rasooli, I (Rasooli, Iraj)[ 1 ] ; Rajabibazl, M (Rajabibazl, Masoumeh)[ 2 ] ; Gargari, SLM aste, F (Araste, Fatemeh)[ 1 ] ; Ebrahimizadeh, W (Ebrahimizadeh, Walead)[ 1 ] ; Rasooli, I (Rasooli, Iraj)[ 1 ] ; Rajabibazl, M (Rajabibazl, Masoumeh)[ 2 ] ; Gargari, SLM A novel VHH nanobody against the active site (the CA domain) of tumor-associated, carbonic anhydrase isoform IX and its usefulness for cancer diagnosis BIOTECHNOLOGY LETTERS Volume: 36 Issue: 1 Pages: 21-28, 2014 Chlapek, P.a , Chovanová, S.ab, Slávikov́a, V.a, Veselská, R. Tumor microenvironment - Possibilities of the research under in vitro conditions BIOTECHNOLOGY LETTERS Volume: 36 Issue: 1 Pages: 21-28, 2014 Casi, G (Casi, Giulio)[ 1 ] ; Neri, D Antibody-Drug Conjugates and Small Molecule-Drug Conjugates: Opportunities and Challenges for the Development of Selective Anticancer Cytotoxic Agents JOURNAL OF MEDICINAL CHEMISTRY Volume: 58 Issue: 22 Pages: 8751-8761, 2015 Chen, Q (Chen, Qian)[ 1 ] ; Liu, XD (Liu, Xiaodong)[ 2 ] ; Chen, JW (Chen, Jiawen)[ 1 ] ; Zeng, JF (Zeng, Jianfeng)[ 3 ] ; Cheng, ZP (Cheng, Zhenping)[ 2 ] ; Liu, Z A Self-Assembled Albumin-Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging ADVANCED MATERIALS Volume: 27 Issue: 43 Pages: 6820 , 2015 Guan, SS (Guan, Siao-Syun)[ 1,2 ] ; Cheng, CC (Cheng, Chun-Chia)[ 1,3 ] ; Ho, AS (Ho, Ai-Sheng)[ 4 ] ; Wang, CC (Wang, Chia-Chi)[ 5,6 ] ; Luo, TY (Luo, Tsai-Yueh)[ 1 ] ; Liao, TZ (Liao, Tse-Zung)[ 1 ] ; Chang, JS (Chang, Jungshan)[ 3 ] ; Wu, CT (Wu, Cheng-Tien)[ 2 ] ; Liu, SH Sulfonamide derivative targeting carbonic anhydrase IX as a nuclear imaging probe for colorectal cancer detection in vivo ONCOTARGET Volume: 6 Issue: 34 Pages: 36139-36155, 2015 Shen, TS (Shen, Tiansheng)[ 1 ] ; Shi, QY (Shi, Qiuying)[ 1 ] ; Velosa, C (Velosa, Claudia)[ 1 ] ; Bai, ST (Bai, Shuting)[ 2 ] ; Thompson, L (Thompson, Lester)[ 3 ] ; Simpson, R (Simpson, Roderick)[ 4 ] ; Wei, S (Wei, Shi)[ 1 ] ; Brandwein-Gensler, M Sinonasal renal cell-like adenocarcinomas: robust carbonic anhydrase expression HUMAN PATHOLOGY Volume: 46 Issue: 11 Pages: 1598-1606, 2015 Gallagher, FA (Gallagher, Ferdia A.)[ 1,2 ] ; Sladen, H (Sladen, Helen)[ 1 ] ; Kettunen, MI (Kettunen, Mikko I.)[ 1 ] ; Serrao, EM (Serrao, Eva M.)[ 1 ] ; Rodrigues, TB (Rodrigues, Tiago B.)[ 1 ] ; Wright, A (Wright, Alan)[ 1 ] ; Gill, AB (Gill, Andrew B.)[ 2 ] ; McGuire, S (McGuire, Sarah)[ 1 ] ; Booth, TC (Booth, Thomas C.)[ 1 ] ; Boren, J (Boren, Joan)[ 1 ] ; McIntyre, A (McIntyre, Alan)[ 3 ] ; Miller, JL (Miller, Jodi L.)[ 1 ] ; Lee, SH (Lee, Shen-Han)[ 1 ] ; Honess, D (Honess, Davina)[ 1 ] ; Day, SE (Day, Sam E.)[ 1 ] ; Hu, DE (Hu, De-En)[ 1 ] ; Howat, WJ (Howat, William J.)[ 1 ] ; Harris, AL (Harris, Adrian L.)[ 3 ] ; Brindle, KM Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized C-13-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors CANCER RESEARCH Volume: 75 Issue: 19 Pages: 4109-4118, 2015 Spugnini, EP (Spugnini, Enrico Pierluigi)[ 1 ] ; Sonveaux, P (Sonveaux, Pierre)[ 2 ] ; Stock, C (Stock, Christian)[ 3 ] ; Perez-Sayans, M (Perez-Sayans, Mario)[ 4 ] ; De Milito, A (De Milito, Angelo)[ 5 ] ; Avnet, S (Avnet, Sofia)[ 6 ] ; Garcia, AG (Garcia Garcia, Abel)[ 4 ] ; Harguindey, S (Harguindey, Salvador)[ 7 ] ; Fais, S Proton channels and exchangers in cancer BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES Volume: 1848 Issue: 10 Pages: 2715-2726 Part: B Special Issue: SI, 2015 Dubois, LJ (Dubois, Ludwig J.)[ 1 ] ; Niemans, R (Niemans, Raymon)[ 1 ] ; van Kuijk, SJA (van Kuijk, Simon J. A.)[ 1 ] ; Panth, KM (Panth, Kranthi M.)[ 1 ] ; Parvathaneni, NK (Parvathaneni, Nanda-Kumar)[ 1,2 ] ; Peeters, SGJA (Peeters, Sarah G. J. A.)[ 1 ] ; Zegers, CML (Zegers, Catharina M. L.)[ 1 ] ; Rekers, NH (Rekers, Nicolle H.)[ 1 ] ; van Gisbergen, MW (van Gisbergen, Marike W.)[ 1 ] ; Biemans, R (Biemans, Rianne)[ 1 ] ; Lieuwes, NG (Lieuwes, Natasja G.)[ 1 ] ; Spiegelberg, L (Spiegelberg, Linda)[ 1 ] ; Yaromina, A (Yaromina, Ala)[ 1 ] ; Winum, JY (Winum, Jean-Yves)[ 2 ] ; Vooijs, M (Vooijs, Marc)[ 1 ] ; Lambin, P New ways to image and target tumour hypoxia and its molecular responses RADIOTHERAPY AND ONCOLOGY Volume: 116 Issue: 3 Pages: 352-357, 2015 Keulers, TG (Keulers, Tom G.)[ 1 ] ; Schaaf, MBE (Schaaf, Marco B. E.)[ 1 ] ; Peeters, HJM (Peeters, Hanneke J. M.)[ 1 ] ; Savelkouls, KGM (Savelkouls, Kim G. M.)[ 1 ] ; Vooijs, MA (Vooijs, Marc A.)[ 1 ] ; Bussink, J (Bussink, Johan)[ 2 ] ; Jutten, B (Jutten, Barry)[ 1 ] ; Rouschop, KMA GABARAPL1 is required for increased EGFR membrane expression during hypoxia RADIOTHERAPY AND ONCOLOGY Volume: 116 Issue: 3 Pages: 417-422 , 2015 Syrjanen, L (Syrjanen, Leo)[ 1,2,3,4 ] ; Valanne, S (Valanne, Susanna)[ 1 ] ; Kuuslahti, M (Kuuslahti, Marianne)[ 1,2,3 ] ; Tuomela, T (Tuomela, Tea)[ 1 ] ; Sriram, A (Sriram, Ashwin)[ 1,5,6 ] ; Sanz, A (Sanz, Alberto)[ 1,5,6 ] ; Jacobs, HT (Jacobs, Howard T.)[ 1,3,7 ] ; Ramet, M (Ramet, Mika)[ 1,8,9,10 ] ; Parkkila, S beta carbonic anhydrase is required for female fertility in Drosophila melanogaster FRONTIERS IN ZOOLOGY Volume: 12, Article Number: 19, 2015 Kim, SH (Kim, Sung Hoon)[ 1 ] ; Madak-Erdogan, Z (Madak-Erdogan, Zeynep)[ 2 ] ; Bae, SC (Bae, Sung Chul)[ 3 ] ; Carlson, KE (Carlson, Kathryn E.)[ 1 ] ; Mayne, CG (Mayne, Christopher G.)[ 1 ] ; Granick, S (Granick, Steve)[ 3 ] ; Katzenellenbogen, BS (Katzenellenbogen, Benita S.)[ 2 ] ; Katzenellenbogen, JA Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 137 Issue: 32 Pages: 10326-10335, 2015 Ledaki, I (Ledaki, Ioanna)[ 1 ] ; McIntyre, A (McIntyre, Alan)[ 1 ] ; Wigfield, S (Wigfield, Simon)[ 1 ] ; Buffa, F (Buffa, Francesca)[ 1 ] ; McGowan, S (McGowan, Simon)[ 1 ] ; Baban, D (Baban, Dilair)[ 2 ] ; Li, JL (Li, Ji-liang)[ 1 ] ; Harris, AL Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition ONCOTARGET Volume: 6 Issue: 23 Pages: 19413-19427, 2015 Parks, SK (Parks, Scott K.)[ 1 ] ; Pouyssegur, J The Na+/HCO3- Co-Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells Volume: 230 Issue: 8 Pages: 1954-1963, 2015 Fu, Q (Fu, Q.)[ 1 ] ; Wang, Y (Wang, Y.)[ 1 ] ; Ma, Y (Ma, Y.)[ 4 ] ; Zhang, D (Zhang, D.)[ 1 ] ; Fallon, JK (Fallon, J. 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EXPERT REVIEW OF ANTICANCER THERAPY Volume: 15 Issue: 6 Pages: 667-676 , 2015 Bouchareb, R (Bouchareb, Rihab)[ 1 ] ; Cote, N (Cote, Nancy)[ 1 ] ; Marie-Chloe-Boulanger (Marie-Chloe-Boulanger)[ 1 ] ; Quang, KL (Khai Le Quang)[ 4 ] ; El Husseini, D (El Husseini, Diala)[ 1 ] ; Asselin, J (Asselin, Jeremie)[ 2 ] ; Hadji, F (Hadji, Fayez)[ 1 ] ; Lachance, D (Lachance, Dominic)[ 4 ] ; Shayhidin, EE (Shayhidin, Elnur Elyar)[ 1 ] ; Mahmut, A (Mahmut, Ablajan)[ 1 ] ; Pibarot, P (Pibarot, Philippe)[ 4 ] ; Bosse, Y (Bosse, Yohan)[ 3 ] ; Messaddeq, Y (Messaddeq, Younes)[ 2 ] ; Boudreau, D (Boudreau, Denis)[ 2 ] ; Marette, A (Marette, Andre)[ 4 ] ; Mathieu, P Carbonic anhydrase XII in valve interstitial cells promotes the regression of calcific aortic valve stenosis OURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Volume: 82 Pages: 104-115, 2015 Yamaguchi, A (Yamaguchi, Ayami)[ 1 ] ; Usami, K (Usami, Katsuaki)[ 2 ] ; Shimabe, M (Shimabe, Munetake)[ 3 ] ; Hasegawa, K (Hasegawa, Kazumasa)[ 4 ] ; Asada, M (Asada, Masao)[ 4 ] ; Motoki, K (Motoki, Kazuhiro)[ 5 ] ; Tahara, T (Tahara, Tomoyuki)[ 6 ] ; Masuda, K The Novel CA IX Inhibition Antibody chKM4927 Shows Anti-tumor Efficacy In Vivo ANTICANCER RESEARCH Volume: 35 Issue: 4 Pages: 1997-2004, 2015 Alafeefy, AM Design, synthesis, and antitumor screening of certain novel tetrahydroquinoline sulfonamides JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY Volume: 30 Issue: 2 Pages: 189-194, 2015 Zeng, W (Zeng, Wen)[ 1,2 ] ; Liu, PY (Liu, Peiyi)[ 1,3 ] ; Pan, WM (Pan, Weimin)[ 4 ] ; Singh, SR (Singh, Shree Ram)[ 5 ] ; Wei, YY Hypoxia and hypoxia inducible factors in tumor metabolism CANCER LETTERS Volume: 356 Issue: 2 Pages: 263-267 Part: A Special Issue: SI, 2015 Dilworth, JR (Dilworth, Jonathan R.)[ 1 ] ; Pascu, SI THE RADIOPHARMACEUTICAL CHEMISTRY OF TECHNETIUM AND RHENIUM Edited by:Long, N; Wong, WT Chemistry of Molecular Imaging Pages: 137-164, 2015 Buarque, CD (Buarque, Camilla D.)[ 1 ] ; Domingos, JLO (Domingos, Jorge L. 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Esterase activity of carbonic anhydrases serves as surrogate for selecting antibodies blocking hydratase activity Journal of Enzyme Inhibition and Medicinal Chemistry Volume 30, Issue 6, 16 March 2015, Pages 955-960 SIDDIQUI, Sabahat Zahra - SARWAR, Afzaal - ABBASI, Muhammad Athar - AZIZ-UR-REHMAN - HUSSAIN, Mazhar - AHMAD, Irshad - SHAH, Syed Adnan Ali. Synthetic N-Aralkylated-N-(2,4-dimethylphenyl) benzenesulfonamides: As Potent Anti-Bacterial Agents. In JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN. ISSN 0253-5106, DEC 2016, vol. 38, no. 6, p. 1151-1158. SCHARTNER, Erik P. - HENDERSON, Matthew R. - PURDEY, Malcolm - DHATRAK, Deepak - MONRO, Tanya M. - GILL, P. Grantley - CALLEN, David F. Cancer Detection in Human Tissue Samples Using a Fiber-Tip pH Probe. In CANCER RESEARCH. ISSN 0008-5472, DEC 1 2016, vol. 76, no. 23, p. 6795-6801. VAN KUIJK, Simon J. A. - GIELING, Roben G. - NIEMANS, Raymon - LIEUWES, Natasja G. - BIEMANS, Rianne - TELFER, Brian A. - HAENEN, Guido R. M. 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