Počet záznamov: 1  

Key targets for multi-target ligands designed to combat neurodegeneration

  1. NázovKey targets for multi-target ligands designed to combat neurodegeneration
    Autor Ramsay Rona R.
    Spoluautori Májeková Magdaléna 1958- SAVEXFATO - Ústav experimentálnej farmakológie a toxikológie SAV    SCOPUS    RID    ORCID

    Medina Milagros

    Valoti Massimo

    Zdroj.dok. Frontiers in Neuroscience. Vol. 10 (2016), art. no. 375
    Structure-based drug design for diagnosis and treatment of neurological diseases. (2017), p. 127-150
    Jazyk dok.eng - angličtina
    KrajinaCH - Švajčiarsko
    PoznámkyMINECO, Spain (BIO2013-42978-P)
    Druh dok.rozpis článkov z periodík (rbx)
    OhlasyBOSWELL, B.A. - KOROL, A. - WEST-MAYS, J.A. - MUSIL, L.S. Dual function of TGF beta in lens epithelial cell fate: implications for secondary cataract. In MOLECULAR BIOLOGY OF THE CELL. ISSN 1059-1524, 2017, vol. 28, no. 7, p. 907-921.
    KNEZ, D. - SOVA, M. - KOSAK, U. - GOBEC, S. Dual inhibitors of cholinesterases and monoamine oxidases for Alzheimer's disease. In FUTURE MEDICINAL CHEMISTRY. ISSN 1756-8919, 2017, vol. 9, no. 8, p. 811-832.
    MONTEIRO, A.F. - SEIDL, C. - SEVERINO, V.G.P. - CARDOSO, C.L. - CASTRO-GAMBOA, I. Biotransformation of labdane and halimane diterpenoids by two filamentous fungi strains. In ROYAL SOCIETY OPEN SCIENCE. ISSN 2054-5703, 2017, vol. 4, no. 11, art. no. 170854.
    KONGSAKON, R. - SATHIRAPONGSASUTI, N. - RERKAMNUAYCHOKE, B. Haplotype Analysis of Genetic Polymorphism in Antisocial Alcoholism. In JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND. ISSN 0125-2208, 2017, vol. 100, no. 6, p. 679-685.
    BOURGANIS, V. - KAMMONA, O. - ALEXOPOULOS, A. - KIPARISSIDES, C. Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics. In EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. ISSN 0939-6411, 2018, vol. 128, p. 337-362.
    EDMONDSON, D.E. - BINDA, C. Monoamine Oxidases. In MEMBRANE PROTEIN COMPLEXES: STRUCTURE AND FUNCTION. ISSN 0306-0225, 2018, vol. 87, p. 117-139.
    GONG, Cheng-Xin - LIU, Fei - IQBAL, Khalid. Multifactorial Hypothesis and Multi-Targets for Alzheimer's Disease. In ALZHEIMER'S DISEASE: NEW BEGINNINGS. Book Series: ‏ Advances in Alzheimers Disease. ISBN:978-1-61499-876-1; 978-1-61499-875-4, ISSN 2210-5727, 2018, vol. 6, p. 105-115.
    KNEZ, D. - COQUELLE, N. - PISLAR, A. - ZAKELJ, S. - JUKIC, M. - SOVA, M. - MRAVLJAK, J. - NACHON, F. - BRAZZOLOTTO, X. - KOS, J. - COLLETIER, J.-P. - GOBEC, S. Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities. In EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0223-5234, 2018, vol. 156, p. 598-617.
    ELSHAFLU, H. - TODOROVIC, T.R. - NIKOLIC, M. - LOLIC, A. - VISNJEVAC, A. - HAGENOW, S. - PADRON, J.M. - GARCIA-SOSA, A.T. - DJORDJEVIC, I.S. - GRUBISIC, S. - STARK, H. - FILIPOVIC, N.R. Selenazolyl-hydrazones as Novel Selective MAO Inhibitors With Antiproliferative and Antioxidant Activities: Experimental and In-silico Studies. In FRONTIERS IN CHEMISTRY. ISSN 2296-2646, 2018, vol. 6, art. no. 247.
    VERMA, M.K. - GOEL, R. - KRISHNADAS, N. - NEMMANI, K.V.S. Targeting glucose-dependent insulinotropic polypeptide receptor for neurodegenerative disorders. In EXPERT OPINION ON THERAPEUTIC TARGETS. ISSN 1472-8222, 2018, vol. 22, no. 7, p. 615-628.
    GONG, Cheng-Xin - LIU, Fei - IQBAL, Khalid. Multifactorial Hypothesis and Multi-Targets for Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2018, vol. 64, no., pp. S107-S117.
    LIN, Jia - ZHAO, Hua-Shan - QIN, Lei - LI, Xue-Nan - ZHANG, Cong - XIA, Jun - LI, Jin-Long. Atrazine Triggers Mitochondrial Dysfunction and Oxidative Stress in Quail (Coturnix C-coturnix) Cerebrum via Activating Xenobiotic-Sensing Nuclear Receptors and Modulating Cytochrome P450 Systems. In JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. ISSN 0021-8561, 2018, vol. 66, no. 25, pp. 6402-6413.
    BENCHEKROUN, M. - MARAMAI, S. Multitarget-directed ligands for neurodegenerative diseases: real opportunity or blurry mirage? In FUTURE MEDICINAL CHEMISTRY. ISSN 1756-8919, 2019, vol. 11, no. 4, p. 261-263.
    KUMAR, A. - SRIVASTAVA, G. - NEGI, A.S. - SHARMA, A. Docking, molecular dynamics, binding energy-MM-PBSA studies of naphthofuran derivatives to identify potential dual inhibitors against BACE-1 and GSK-3. In JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. ISSN 0739-1102, 2019, vol. 37, no. 2, p. 275-290.
    SAVELIEFF, M.G. - NAM, G. - KANG, J. - LEE, H.J. - LEE, M. - LIM, M.H. Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the Last Decade. In CHEMICAL REVIEWS. ISSN 0009-2665, 2019, vol. 119, no. 2, p. 1221-1322.
    PROSCHAK, E. - STARK, H. - MERK, D. Polypharmacology by Design: A Medicinal Chemist's Perspective on Multitargeting Compounds. In JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623, 2019, vol. 62, no. 2, p. 420-444.
    SANCHEZ-VIDANA, D.I. - CHOW, J.K.W. - HU, S.Q. - LAU, B.W.M. - HAN, Y.-F. Molecular Targets of Bis (7)-Cognitin and Its Relevance in Neurological Disorders: A Systematic Review. In FRONTIERS IN NEUROSCIENCE. ISSN 1662-453X, 2019, vol. 13, no. May, art. no. 445.
    JAYARAJ, Abhilash - BHAT, Ruchika - PATHAK, Amita - SINGH, Manpreet - JAYARAM, B. Development of a web-server for identification of common lead molecules for multiple protein targets. In METHODS IN PHARMACOLOGY AND TOXICOLOGY. ISSN 1557-2153, 2019, pp. 487-504.
    KNEZ, D. - SOSIC, I. - PISLAR, A. - MITROVIC, A. - JUKIC, M. - KOS, J. - GOBEC, S. Biological Evaluation of 8-Hydroxyquinolines as Multi-Target Directed Ligands for Treating Alzheimer's Disease. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, 2019, vol. 16, no. 9, p. 801-814.
    CHAVARRIA, D. - FERNANDES, C. - AGUIAR, B. - SILVA, T. - GARRIDO, J. - REMIAO, F. - OLIVEIRA, P.J. - URIARTE, E. - BORGES, F. Insights into the Discovery of Novel Neuroprotective Agents: A Comparative Study between Sulfanylcinnamic Acid Derivatives and Related Phenolic Analogues. In MOLECULES. eISSN: 1420-3049, 2019, vol. 24, no. 23, art. no. 4405.
    OH, J.M. - KANG, M.G. - HONG, A. - PARK, J.E. - KIM, S.H. - LEE, J.P. - BAEK, S.C. - PARK, D. - NAM, S.J. - CHO, M.L. - KIM, H. Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives. In INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. ISSN 0141-8130, 2019, vol. 137, p. 426-432.
    MATHEW, B. - PARAMBI, D.G.T. - MATHEW, G.E. - UDDIN, M.S. - INASU, S.T. - KIM, H. - MARATHAKAM, A. - UNNIKRISHNAN, M.K. - CARRADORI, S. Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases. In ARCHIV DER PHARMAZIE. ISSN 0365-6233, 2019, vol. 352, no. 11, art. no. e1900177.
    OH, J.M. - JANG, H.J. - KIM, W.J. - KANG, M.G. - BAEK, S.C. - LEE, J.P. - PARK, D. - OH, S.R. - KIM, H. Calycosin and 8-O-methylretusin isolated from Maackia amurensis as potent and selective reversible inhibitors of human monoamine oxidase-B. In INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. ISSN 0141-8130, 2020, vol. 151, p. 441-448.
    PLAZAS, Gonzales E. - HAGENOW, S. - MURILLO, M.A. - STARK, H. - CUCA, L.E. Isoquinoline alkaloids from the roots of Zanthoxylum rigidum as multi-target inhibitors of cholinesterase, monoamine oxidase A and A beta(1-42) aggregation. In BIOORGANIC CHEMISTRY. ISSN 0045-2068, 2020, vol. 98, art. no. 103722.
    KIPARISSIDES, C. - VASILEIADOU, A. - KARAGEORGOS, F. - SERPETSI, S. A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics. In INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH. ISSN 0888-5885, 2020, vol. 59, no. 6, p. 2548-2565.
    HAGENOW, J. - HAGENOW, S. - GRAU, K. - KHANFAR, M. - HEFKE, L. - PROSCHAK, E. - STARK, H. Reversible Small Molecule Inhibitors of MAO A and MAO B with Anilide Motifs. In DRUG DESIGN DEVELOPMENT AND THERAPY. ISSN 1177-8881, 2020, vol. 14, p. 371-393.
    KNEZ, D. - SOSIC, I. - MITROVIC, A. - PISLAR, A. - KOS, J. - GOBEC, S. 8-Hydroxyquinoline-based anti-Alzheimer multimodal agents. In MONATSHEFTE FUR CHEMIE. ISSN 0026-9247, 2020, vol. 151, no. 7, p. 1111-1120.
    GULCAN, H.O. - ORHAN, I.E. A Recent Look into Natural Products that have Potential to Inhibit Cholinesterases and Monoamine Oxidase B: Update for 2010-2019. In COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING. ISSN 1386-2073, 2020, vol. 23, no. 9, p. 862-876.
    HEO, J.H. - EOM, B.H. - RYU, H.W. - KANG, M.G. - PARK, J.E. - KIM, D.Y. - KIM, J.H. - PARK, D. - OH, S.R. - KIM, H. Acetylcholinesterase and butyrylcholinesterase inhibitory activities of khellactone coumarin derivatives isolated from Peucedanum japonicum Thurnberg. In SCIENTIFIC REPORTS. ISSN 2045-2322, 2020, vol. 10, no. 1.
    DU, W.Q. - LIANG, X. - WANG, S.Z. - LEE, P. - ZHANG, Y.L. The Underlying Mechanism of Paeonia lactiflora Pall. in Parkinson's Disease Based on a Network Pharmacology Approach. In FRONTIERS IN PHARMACOLOGY. ISSN 1663-9812, 2020, vol. 11.
    VOLONTE, C. - MORELLO, G. - SPAMPINATO, A.G. - AMADIO, S. - APOLLONI, S. - D'AGATA, V. - CAVALLARO, S. Omics-based exploration and functional validation of neurotrophic factors and histamine as therapeutic targets in ALS. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, 2020, vol. 62.
    ADEDAYO, Bukola C. - ADEBAYO, Adeniyi A. - OBOH, Ganiyu. In vitro antioxidant and anti-cholinesterase properties of essential oils from pepper fruits (Dennettia tripetala g. baker). In Tropical Journal of Natural Product Research. ISSN 26160684, 2020-09-01, 4, 9, pp. 596-600.
    CHAVARRIA, D. - DA SILVA, O. - BENFEITO, S. - BARREIRO, S. - GARRIDO, J. - CAGIDE, F. - SOARES, P. - REMIAO, F. - BRAZZOLOTTO, X. - NACHON, F. - OLIVEIRA, P.J. - DIAS, J. - BORGES, F. Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases. In ANTIOXIDANTS. eISSN: 2076-3921, 2021, vol. 10, no. 2.
    FAYAZI, N. - SHEYKHHASAN, M. - ASL, S.S. - NAJAFI, R. Stem Cell-Derived Exosomes: a New Strategy of Neurodegenerative Disease Treatment. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, JUL 2021, vol. 58, no. 7, p. 3494-3514.
    HAGENOW, S. - AFFINI, A. - PIOLI, E.Y. - HINZ, S. - ZHAO, Y. - PORRAS, G. - NAMASIVAYAM, V. - MULLER, C.E. - LIN, J.S. - BEZARD, E. - STARK, H. Adenosine A(2A)R/A(1)R Antagonists Enabling Additional H3R Antagonism for the Treatment of Parkinson's Disease. In JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623, JUN 24 2021, vol. 64, no. 12, p. 8246-8262.
    QUEZADA, E. - RODRIGUEZ-ENRIQUEZ, F. - LAGUNA, R. - CUTRIN, E. - OTERO, F. - URIARTE, E. - VINA, D. Curcumin-Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders. In MOLECULES. AUG 2021, vol. 26, no. 15.
    PLAZAS, Erika - AVILA, Monica C. M. - MUNOZ, Diego R. - CUCA, Luis E. S. Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases. In PHARMACOLOGICAL RESEARCH. ISSN 1043-6618, 2022, vol. 177, no., pp. Dostupné na: https://doi.org/10.1016/j.phrs.2022.106126.
    CETIN, Sandra - KNEZ, Damijan - GOBEC, Stanislav - KOS, Janko - PISLAR, Anja. Cell models for Alzheimer's and Parkinson's disease: At the interface of biology and drug discovery. In BIOMEDICINE & PHARMACOTHERAPY. ISSN 0753-3322, 2022, vol. 149, no., pp. Dostupné na: https://doi.org/10.1016/j.biopha.2022.112924.
    RAČKOVÁ, Lucia - CSEKES, Erika. Redox aspects of cytotoxicity and anti-neuroinflammatory profile of chloroquine and hydroxychloroquine in serum-starved BV-2 microglia. In Toxicology and Applied Pharmacology, 2022-07-15, 447, pp. ISSN 0041008X. Dostupné na: https://doi.org/10.1016/j.taap.2022.116084.
    LAWAL, B.A. - AYIPO, Y.O. - ADEKUNLE, A.O. - AMALI, M.O. - BADEGGI, U.M. - ALANANZEH, W.A. - MORDI, M.N. Phytoconstituents of iDatura metel/i extract improved motor coordination in haloperidol-induced cataleptic mice: Dual-target molecular docking and behavioural studies. In JOURNAL OF ETHNOPHARMACOLOGY. ISSN 0378-8741, JAN 10 2023, vol. 300. Dostupné na: https://doi.org/10.1016/j.jep.2022.115753.
    CARRADORI, S. - FANTACUZZI, M. - AMMAZZALORSO, A. - ANGELI, A. - DE FILIPPIS, B. - GALATI, S. - PETZER, A. - PETZER, J.P. - POLI, G. - TUCCINARDI, T. - AGAMENNONE, M. - SUPURAN, C.T. Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases?. In MOLECULES. NOV 2022, vol. 27, no. 22. Dostupné na: https://doi.org/10.3390/molecules27227816.
    ATLANTE, A. - AMADORO, G. - LATINA, V. - VALENTI, D. Therapeutic Potential of Targeting Mitochondria for Alzheimer's Disease Treatment. In JOURNAL OF CLINICAL MEDICINE. NOV 2022, vol. 11, no. 22. Dostupné na: https://doi.org/10.3390/jcm11226742.
    HAJJO, R. - SABBAH, D.A. - ABUSARA, O.H. - AL BAWAB, A.Q. A Review of the Recent Advances in Alzheimer's Disease Research and the Utilization of Network Biology Approaches for Prioritizing Diagnostics and Therapeutics. In DIAGNOSTICS. DEC 2022, vol. 12, no. 12. Dostupné na: https://doi.org/10.3390/diagnostics12122975.
    RACKOVá, L. - CSEKES, E. Redox aspects of cytotoxicity and anti-neuroinflammatory profile of chloroquine and hydroxychloroquine in serum-starved BV-2 microglia. In TOXICOLOGY AND APPLIED PHARMACOLOGY. ISSN 0041-008X, JUL 15 2022, vol. 447. Dostupné na: https://doi.org/10.1016/j.taap.2022.116084.
    OH, J.M. - JANG, H.J. - KANG, M.G. - MUN, S.K. - PARK, D. - HONG, S.J. - KIM, M.H. - KIM, S.Y. - YEE, S.T. - KIM, H. Medicarpin and Homopterocarpin Isolated from iCanavalia lineata/i as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B. In MOLECULES. JAN 2023, vol. 28, no. 1. Dostupné na: https://doi.org/10.3390/molecules28010258.
    ISHAQUE, A. - SALIM, A. - SIMJEE, S.U. - KHAN, I. - ADLI, D.S.H. Alpha terpineol directs bone marrow mesenchymal stem cells toward neuronal lineage through regulation of wnt signaling pathway. In CELL BIOCHEMISTRY AND FUNCTION. ISSN 0263-6484, MAR 2023, vol. 41, no. 2, p. 223-233. Dostupné na: https://doi.org/10.1002/cbf.3775.
    JIN, Q.H. - ZHANG, L.P. - ZHANG, S.S. - ZHUANG, D.N. - ZHANG, C.Y. - ZHENG, Z.J. - GUAN, L.P. (iS/i)-iN/i-Benzyl-1-phenyl-3,4-dihydroisoqunoline-2(1iH/i)- carboxamide Derivatives, Multi-Target Inhibitors of Monoamine Oxidase and Cholinesterase: Design, Synthesis, and Biological Activity. In MOLECULES. FEB 2023, vol. 28, no. 4. Dostupné na: https://doi.org/10.3390/molecules28041654.
    KategóriaADMA - Vedecké práce v zahraničných impaktovaných časopisoch registrovaných vo WOS Core Collection alebo SCOPUS
    Kategória (od 2022)V3 - Vedecký výstup publikačnej činnosti z časopisu
    Typ výstupučlánok
    Rok vykazovania2016
    Registrované vWOS
    Registrované vSCOPUS
    DOI 10.3389/fnins.2016.00375
    článok

    článok

    Názov súboruPrístupVeľkosťStiahnutéTypLicence
    Key targets for multi-target ligands designed to combat neurodegeneration.pdfPrístupný2.9 MB9Vydavateľská verzia
    rokCCIFIF Q (best)JCR Av Jour IF PercSJRSJR Q (best)CiteScore
    N
    rok vydaniarok metrikyIFIF Q (best)SJRSJR Q (best)
    201720163.566Q21.941Q1
Počet záznamov: 1  

  Tieto stránky využívajú súbory cookies, ktoré uľahčujú ich prezeranie. Ďalšie informácie o tom ako používame cookies.