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Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer’s disease: a randomised, double-blind, placebo-controlled, phase 1 trial
Title Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer’s disease: a randomised, double-blind, placebo-controlled, phase 1 trial Author Novák Petr SCOPUS Kontseková Eva SCOPUS Žilka Norbert SCOPUS Kováčech Branislav SCOPUS Škrabana Rostislav ORCID Vince Kážmérová Zuzana Fialová Ľubica ORCID Prčina Michal Parrák Vojtech Novák Michal SCOPUS Co-authors Schmidt R. Katina S. Dal-Bianco P. Brunner M. Staffen W. Rainer M. Ondruš M. Ropele S. Smíšek M. Sivák R. Winblad B. Source document Lancet Neurology. Vol. 16 (2017) p.123-34 Language eng - English Document kind rozpis článkov z periodík (rbx) Citations SAINT-AUBERT, Laure - LEMOINE, Laetitia - CHIOTIS, Konstantinos - LEUZY, Antoine - RODRIGUEZ-VIEITEZ, Elena - NORDBERG, Agneta. Tau PET imaging: present and future directions. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, 2017, vol. 12, no., pp. ORR, Miranda E. - SULLIVAN, A. Campbell - FROST, Bess. A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies. In TRENDS IN PHARMACOLOGICAL SCIENCES. ISSN 0165-6147, 2017, vol. 38, no. 7, pp. 637-648. COUGHLIN, David - IRWIN, David J. Emerging Diagnostic and Therapeutic Strategies for Tauopathies. In CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS. ISSN 1528-4042, 2017, vol. 17, no. 9, pp. GOZES, Illana - HOEGLINGER, Gunter - QUINN, James P. - HOOPER, Nigel M. - HOGLUND, Kina. Tau Diagnostics and Clinical Studies. In JOURNAL OF MOLECULAR NEUROSCIENCE. ISSN 0895-8696, 2017, vol. 63, no. 2, pp. 123-130. JOUANNE, Marie - RAULT, Sylvain - VOISIN-CHIRET, Anne-Sophie. Tau protein aggregation in Alzheimer's disease: An attractive target for the development of novel therapeutic agents. In EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0223-5234, 2017, vol. 139, no., pp. 153-167. KHOURY, Rita - PATEL, Kush - GOLD, Jake - HINDS, Stephanie - GROSSBERG, George T. Recent Progress in the Pharmacotherapy of Alzheimer's Disease. In DRUGS & AGING. ISSN 1170-229X, 2017, vol. 34, no. 11, pp. 811-820. KLAVER, Andrea C. - COFFEY, Mary P. - BENNETT, David A. - LOEFFLER, David A. Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, 2017, vol. 6, no., pp. LI, Chuanzhou - GOTZ, Jurgen. Tau-based therapies in neurodegeneration: opportunities and challenges. In NATURE REVIEWS DRUG DISCOVERY. ISSN 1474-1776, 2017, vol. 16, no. 12, pp. 863-883. BRACZYNSKI, Anne K. - SCHULZ, Joerg B. - BACH, Jan-Philipp. Vaccination strategies in tauopathies and synucleinopathies. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, 2017, vol. 143, no. 5, pp. 467-488. SUZUKI, Kazushi - IWATA, Atsushi - IWATSUBO, Takeshi. The past, present, and future of disease-modifying therapies for Alzheimer's disease. In PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES. ISSN 0386-2208, 2017, vol. 93, no. 10, pp. 757-771. PADRTOVA, Tereza - MARVANOVA, Pavlina - ODEHNALOVA, Klara - KUBINOVA, Renata - PARRAVICINI, Oscar - GARRO, Adriana - ENRIZ, Ricardo D. - HUMPA, Otakar - ORAVEC, Michal - MOKRY, Petr. Synthesis, Analysis, Cholinesterase-Inhibiting Activity and Molecular Modelling Studies of 3-(Dialkylamino)-2-hydroxypropyl 4-[(Alkoxy-carbonyl)amino]benzoates and Their Quaternary Ammonium Salts. In MOLECULES, 2017, vol. 22, no. 12, pp. WU, Xi-Lin - PINA-CRESPO, Juan - ZHANG, Yun-Wu - CHEN, Xiao-Chun - XU, Hua-Xi. Tau-mediated Neurodegeneration and Potential Implications in Diagnosis and Treatment of Alzheimer's Disease. In CHINESE MEDICAL JOURNAL. ISSN 0366-6999, 2017, vol. 130, no. 24, pp. 2978-2990. DOCHNIAK, Michael J. Healing the mind Alzheimer's disease Thinking patents (2008 to 2016). In Healing the Mind Alzheimer's Disease Thinking Patents (2008 to 2016), 2017-01-01, pp. 1-377. VIDAL, J. Neurodegenerative diseases and vaccines. In Vacunas. ISSN 15769887, 2017-01-01, 18, 1, pp. 1-2. TOMITA, Taisuke. Aberrant proteolytic processing and therapeutic strategies in Alzheimer disease. In Advances in Biological Regulation. ISSN 22124926, 2017-05-01, 64, pp. 33-38. XU, Juan - ZHAO, Wenjuan - LIU, Ye. Advances in immunotherapy for Alzheimer's disease. In Chinese Journal of Neurology. ISSN 10067876, 2017-11-08, 50, 11, pp. 859-862. QOSA, Hisham - VOLPE, Donna A. The development of biological therapies for neurological diseases: moving on from previous failures. In EXPERT OPINION ON DRUG DISCOVERY. ISSN 1746-0441, 2018, vol. 13, no. 4, pp. 283-293. SHAHPASAND, Koorosh - SHAMLOO, Alireza Sepehri - NABAVI, Seyed Massood - LU, Kun Ping - ZHOU, Xiao Zhen. Tau immunotherapy: Hopes and hindrances. In HUMAN VACCINES & IMMUNOTHERAPEUTICS. ISSN 2164-5515, 2018, vol. 14, no. 2, pp. 277-284. IQBAL, Khalid - LIU, Fei - GONG, Cheng-Xin. Recent developments with tau-based drug discovery. In EXPERT OPINION ON DRUG DISCOVERY. ISSN 1746-0441, 2018, vol. 13, no. 5, pp. 399-410. SHOEIBI, Ali - OLFATI, Nahid - LITVAN, Irene. Preclinical, phase I, and phase II investigational clinical trials for treatment of progressive supranuclear palsy. In EXPERT OPINION ON INVESTIGATIONAL DRUGS. ISSN 1354-3784, 2018, vol. 27, no. 4, pp. 349-361. CACABELOS, Ramon. Have there been improvements in Alzheimer's disease drug discovery over the past 5 years? In EXPERT OPINION ON DRUG DISCOVERY. ISSN 1746-0441, 2018, vol. 13, no. 6, pp. 523-538. DUPONT, Anne-Claire - LARGEAU, Berenger - GUILLOTEAU, Denis - RIBEIRO, Maria Joao Santiago - ARLICOT, Nicolas. The Place of PET to Assess New Therapeutic Effectiveness in Neurodegenerative Diseases. In CONTRAST MEDIA & MOLECULAR IMAGING. ISSN 1555-4309, 2018, vol., no., pp. BAGNATO, Sergio - ANDRIOLO, Maria - BOCCAGNI, Cristina - SANT'ANGELO, Antonino - D'IPPOLITO, Maria Enza - GALARDI, Giuseppe. Dissociation of cerebrospinal fluid amyloid- and tau levels in patients with prolonged posttraumatic disorders of consciousness. In BRAIN INJURY. ISSN 0269-9052, 2018, vol. 32, no. 8, pp. 1056-1060. GAUTHIER, Serge - NG, Kok Pin - PASCOAL, Tharick A. - ZHANG, Hua - ROSA-NETO, Pedro. Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2018, vol. 64, no., pp. S23-S31. SIGURDSSON, Einar M. Tau Immunotherapies for Alzheimer's Disease and Related Tauopathies: Progress and Potential Pitfalls. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2018, vol. 64, no., pp. S555-S565. HERLINE, Krystal - DRUMMOND, Eleanor - WISNIEWSKI, Thomas. Recent advancements toward therapeutic vaccines against Alzheimer's disease. In EXPERT REVIEW OF VACCINES. ISSN 1476-0584, 2018, vol. 17, no. 8, pp. 707-721. DEUTSCHLANDER, A. B. - ROSS, O. A. - DICKSON, D. W. - WSZOLEK, Z. K. Atypical parkinsonian syndromes: a general neurologist's perspective. In EUROPEAN JOURNAL OF NEUROLOGY. ISSN 1351-5101, 2018, vol. 25, no. 1, pp. 41-58. KUPPILI, Pooja Patnaik - MANOHAR, Harshini - MENON, Vikas. Current status of vaccines in psychiatry-A narrative review. In ASIAN JOURNAL OF PSYCHIATRY. ISSN 1876-2018, 2018, vol. 31, no., pp. 112-120. SIGURDSSON, Einar M. Tau Immunotherapies for Alzheimer's Disease and Related Tauopathies: Progress and Potential Pitfalls. In ALZHEIMER'S DISEASE: NEW BEGINNINGS. ISSN 2210-5727, 2018, vol. 6, no., pp. 553-563. GAUTHIER, Serge - NG, Kok Pin - PASCOAL, Tharick A. - ZHANG, Hua - ROSA-NETO, Pedro. Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment. In ALZHEIMER'S DISEASE: NEW BEGINNINGS. ISSN 2210-5727, 2018, vol. 6, no., pp. 21-29. DU, Xiaoguang - WANG, Xinyi - GENG, Meiyu. Alzheimer's disease hypothesis and related therapies. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, 2018, vol. 7, no., pp. OTTO, Markus. Comment: Tau CSF proteins for diagnosis but tau PET imaging for AD diagnosis and staging. In NEUROLOGY. ISSN 0028-3878, 2018, vol. 90, no. 5, pp. 216-216. CROISSANT, Jonas G. - FATIEIEV, Yevhen - ALMALIK, Abdulaziz - KHASHAB, Niveen M. Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications. In ADVANCED HEALTHCARE MATERIALS. ISSN 2192-2640, 2018, vol. 7, no. 4, pp. CROISSANT, Jonas G. - FATIEIEV, Yevhen - ALMALIK, Abdulaziz - KHASHAB, Niveen M. Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications. In ADVANCED HEALTHCARE MATERIALS. ISSN 2192-2640, 2018, vol. 7, no. 4, pp. BITTAR, Alice - SENGUPTA, Urmi - KAYED, Rakez. Prospects for strain-specific immunotherapy in Alzheimer's disease and tauopathies. In NPJ VACCINES, 2018, vol. 3, no., pp. MEDINA, Miguel. An Overview on the Clinical Development of Tau-Based Therapeutics. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, 2018, vol. 19, no. 4, pp. HAMPEL, Harald - VERGALLO, Andrea - AGUILAR, Lisi Flores - BENDA, Norbert - BROICH, Karl - CUELLO, A. Claudio - CUMMINGS, Jeffrey - DUBOIS, Bruno - FEDEROFF, Howard J. - FIANDACA, Massimo - GENTHON, Remy - HABERKAMP, Marion - KARRAN, Eric - MAPSTONE, Mark - PERRY, George - SCHNEIDER, Lon S. - WELIKOVITCH, Lindsay A. - WOODCOCK, Janet - BALDACCI, Filippo - LISTA, Simone. Precision pharmacology for Alzheimer's disease. In PHARMACOLOGICAL RESEARCH. ISSN 1043-6618, 2018, vol. 130, no., pp. 331-365. SEMLER, Elisa - ANDERL-STRAUB, Sarah - UTTNER, Ingo - DIEHL-SCHMID, Janine - DANEK, Adrian - EINSIEDLER, Beate - FASSBENDER, Klaus - FLIESSBACH, Klaus - HUPPERTZ, Hans-Jurgen - JAHN, Holger - KORNHUBER, Johannes - LANDWEHRMEYER, Bernhard - LAUER, Martin - MUCHE, Rainer - PRUDLO, Johannes - SCHNEIDER, Anja - SCHROETER, Matthias L. - LUDOLPH, Albert C. - OTTO, Markus. A language-based sum score for the course and therapeutic intervention in primary progressive aphasia. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2018, vol. 10, no., pp. BENHAMRON, Sandrine - ROZENSTEIN-TSALKOVICH, Lea - NITZAN, Keren - ABRAMSKY, Oded - ROSENMANN, Hanna. Phos-tau peptide immunization of amyloid-tg-mice reduced non-mutant phos-tau pathology, improved cognition and reduced amyloid plaques. In EXPERIMENTAL NEUROLOGY. ISSN 0014-4886, 2018, vol. 303, no., pp. 48-58. VOLHARD, Theresia - JESSEN, Frank - KLEINEIDAM, Luca - WOLFSGRUBER, Steffen - LANZERATH, Dirk - WAGNER, Michael - MAIER, Wolfgang. Advance directives for future dementia can be modified by a brief video presentation on dementia care: An experimental study. In PLOS ONE. ISSN 1932-6203, 2018, vol. 13, no. 5, pp. JI, Mei - XIE, Xi-xiu - LIU, Dong-qun - YU, Xiao-lin - ZHANG, Yue - ZHANG, Ling-xiao - WANG, Shao-wei - HUANG, Ya-ru - LIU, Rui-tian. Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2018, vol. 10, no., pp. CHONG, Fong Ping - NG, Khuen Yen - KOH, Rhun Yian - CHYE, Soi Moi. Tau Proteins and Tauopathies in Alzheimer's Disease. In CELLULAR AND MOLECULAR NEUROBIOLOGY. ISSN 0272-4340, 2018, vol. 38, no. 5, pp. 965-980. CONGDON, Erin E. - SIGURDSSON, Einar M. Tau-targeting therapies for Alzheimer disease. In NATURE REVIEWS NEUROLOGY. ISSN 1759-4758, 2018, vol. 14, no. 7, pp. 399-415. DUARTE, A. I. - SANTOS, M. S. - OLIVEIRA, C. R. - MOREIRA, P. I. Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease. In NEUROPHARMACOLOGY. ISSN 0028-3908, 2018, vol. 136, no., pp. 223-242. WINKLER, David - LEYHE, Thomas. Alzheimer's disease State of the art, and emerging diagnostics and therapeutics. In THERAPEUTISCHE UMSCHAU. ISSN 0040-5930, 2018, vol. 75, no. 7, pp. 432-437. SCHWEYER, Kerstin - LEVIN, Johannes - HOEGLINGER, Guenter U. Current therapy studies in atypical Parkinson syndromes. In FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE. ISSN 0720-4299, 2018, vol. 86, no., pp. S21-S29. KRESTOVA, Michala - RICNY, Jan - BARTOS, Ales. Changes in concentrations of tau-reactive antibodies are dependent on sex in Alzheimer's disease patients. In JOURNAL OF NEUROIMMUNOLOGY. ISSN 0165-5728, 2018, vol. 322, no., pp. 1-8. CAO, Lei - CAO, Xu - ZHOU, Yebo - NAGPURE, Bhushan Vijay - WU, Zhi-Yuan - HU, Li Fang - YANG, Yong - SETHI, Gautam - MOORE, Philp K. - BIAN, Jin-Song. Hydrogen sulfide inhibits ATP-induced neuroinflammation and A beta(1-42) synthesis by suppressing the activation of STAT3 and cathepsin S. In BRAIN BEHAVIOR AND IMMUNITY. ISSN 0889-1591, 2018, vol. 73, no., pp. 603-614. KOVACS, G. G. - RESPONDEK, G. - VAN EIMEREN, T. - HOELLER, E. - LEVIN, J. - MUELLER, U. - SCHWARZ, S. - ROESLER, T. W. - SCHWEYER, K. - HOEGLINGER, G. U. Tauopathies. From molecule to therapy. In NERVENARZT. ISSN 0028-2804, 2018, vol. 89, no. 10, pp. 1083-1094. BI, Xia-an - XU, Qian - LUO, Xianhao - SUN, Qi - WANG, Zhigang. Analysis of Progression Toward Alzheimer's Disease Based on Evolutionary Weighted Random Support Vector Machine Cluster. In FRONTIERS IN NEUROSCIENCE, 2018, vol. 12, no., pp. SASMITA, Andrew Octavian - KURUVILLA, Joshua - LING, Anna Pick Kiong. Harnessing neuroplasticity: modern approaches and clinical future. In INTERNATIONAL JOURNAL OF NEUROSCIENCE. ISSN 0020-7454, 2018, vol. 128, no. 11, pp. 1061-1077. ROSENBERG, Roger N. - FU, Min - LAMBRACHT-WASHINGTON, Doris. Active full-length DNA A beta(42) immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2018, vol. 10, no., pp. SUN, Bin-Lu - LI, Wei-Wei - ZHU, Chi - JIN, Wang-Sheng - ZENG, Fan - LIU, Yu-Hui - BU, Xian-Le - ZHU, Jie - YAO, Xiu-Qing - WANG, Yan-Jiang. Clinical Research on Alzheimer's Disease: Progress and Perspectives. In NEUROSCIENCE BULLETIN. ISSN 1673-7067, 2018, vol. 34, no. 6, pp. 1111-1118. BIJARI, Nooshin - BALALAIE, Saeed - AKBARI, Vali - GOLMOHAMMADI, Farhad - MORADI, Sajad - ADIBI, Hadi - KHODARAHMI, Reza. Effective suppression of the modified PHF6 peptide/1N4R Tau amyloid aggregation by intact curcumin, not its degradation products: Another evidence for the pigment as preventive/therapeutic "functional food". In INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. ISSN 0141-8130, 2018, vol. 120, no., pp. 1009-1022. LI, Hongmei - LIU, Chia-Chen - ZHENG, Hui - HUANG, Timothy Y. Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer's diseaseconformist, nonconformist, and realistic prospects for AD pathogenesis. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, 2018, vol. 7, no., pp. ANISMAN, Hymie - HAYLEY, Shawn - KUSNECOV, Alexander. The immune system and mental health. In The Immune System and Mental Health, 2018-01-01, pp. 1-700. KOYNOVA, Rumiana - TENCHOV, Boris. Natural product formulations for the prevention and treatment of alzheimer's disease: A patent review. In Recent Patents on Drug Delivery and Formulation. ISSN 18722113, 2018-01-01, 12, 1, pp. 23-39. WELLER, Jason - BUDSON, Andrew. Current understanding of Alzheimer's disease diagnosis and treatment. In F1000Research. ISSN 20461402, 2018-01-01, 7, pp. MORAES, Marcela Usmari - GAUDET, Timothy J. Immunotherapeutic and pharmacological approaches for the treatment of Alzheimer's disease. In Bioscience Horizons, 2018-01-01, 11, pp. BAKER, Jeremy D. - WEBSTER, Jack M. - SHELTON, Lindsey B. - KOREN, John - UVERSKY, Vladimir N. - BLAIR, Laura J. - DICKEY, Chad A. Neurodegenerative Diseases as Protein Folding Disorders. In The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms, 2018-04-04, pp. 243-267. WINKLER, D. Alzheimer's disease – state of the art, and emerging diagnostics and therapeutics. IN Therapeutische Umschau, 2018, vol. 75, iss. 7, p. 432-437. ISSN 0040-5930. TAM, Chit - WONG, Jack Ho - NG, Tzi Bun - TSUI, Stephen Kwok Wing - ZUO, Tao. Drugs for Targeted Therapies of Alzheimer's Disease. In CURRENT MEDICINAL CHEMISTRY. ISSN 0929-8673, 2019, vol. 26, no. 2, pp. 335-359. GUEST, Francesca L. Early Detection and Treatment of Patients with Alzheimer's Disease: Future Perspectives. In REVIEWS ON BIOMARKER STUDIES IN PSYCHIATRIC AND NEURODEGENERATIVE DISORDERS. ISSN 0065-2598, 2019, vol. 1118, no., pp. 295-317. LOGROSCINO, Giancarlo - IMBIMBO, Bruno P. - LOZUPONE, Madia - SARDONE, Rodolfo - CAPOZZO, Rosa - BATTISTA, Petronilla - ZECCA, Chiara - DIBELLO, Vittorio - GIANNELLI, Gianluigi - BELLOMO, Antonello - GRECO, Antonio - DANIELE, Antonio - SERIPA, Davide - PANZA, Francesco. Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs. In EXPERT OPINION ON PHARMACOTHERAPY. ISSN 1465-6566, 2019, vol. 20, no. 9, pp. 1091-1107. LEWIS, Patrick A. - SPILLANE, Jennifer E. ALZHEIMER'S DISEASE AND DEMENTIA. In MOLECULAR AND CLINICAL PATHOLOGY OF NEURODEGENERATIVE DISEASE, 2019, vol., no., pp. 25-82. IQBAL, Khalid - LIU, Fei - GONG, ChengXin - DAI, Chunling - HU, Wen. Why delay in effective treatment for Alzheimer's disease and related conditions. In MOLECULAR BIOLOGY OF NEURODEGENERATIVE DISEASES: VISIONS FOR THE FUTURE, PT A. ISSN 1877-1173, 2019, vol. 168, no., pp. 243-256. CHU, Dandan - LIU, Fei. Pathological Changes of Tau Related to Alzheimer's Disease. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, 2019, vol. 10, no. 2, pp. 931-944. DONG, Yuan - LI, Xiaoheng - CHENG, Jinbo - HOU, Lin. Drug Development for Alzheimer's Disease: Microglia Induced Neuroinflammation as a Target? In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, 2019, vol. 20, no. 3, pp. LAO, Kejing - JI, Naichun - ZHANG, Xiaohua - QIAO, Wenwei - TANG, Zhishu - GOU, Xingchun. Drug development for Alzheimer's disease: review. In JOURNAL OF DRUG TARGETING. ISSN 1061-186X, 2019, vol. 27, no. 2, pp. 164-173. SHARMA, Piyoosh - SRIVASTAVA, Pavan - SETH, Ankit - TRIPATHI, Prabhash Nath - BANERJEE, Anupam G. - SHRIVASTAVA, Sushant K. Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, 2019, vol. 174, no., pp. 53-89. PANKIEWICZ, Joanna E. - SANCHEZ, Sandrine - KIRSHENBAUM, Kent - KASCSAK, Regina B. - KASCSAK, Richard J. - SADOWSKI, Martin J. Anti-prion Protein Antibody 6D11 Restores Cellular Proteostasis of Prion Protein Through Disrupting Recycling Propagation of PrPSc and Targeting PrPSc for Lysosomal Degradation. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, 2019, vol. 56, no. 3, pp. 2073-2091. MARTINELLI, Anne H. S. - LOPES, Fernanda C. - JOHN, Elisa B. O. - CARLINI, Celia R. - LIGABUE-BRAUN, Rodrigo. Modulation of Disordered Proteins with a Focus on Neurodegenerative Diseases and Other Pathologies. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, 2019, vol. 20, no. 6, pp. SILVA, M. Catarina - FERGUSON, Fleur M. - CAI, Quan - DONOVAN, Katherine A. - NANDI, Ghata - PATNAIK, Debasis - ZHANG, Tinghu - HUANG, Hai-Tsang - LUCENTE, Diane E. - DICKERSON, Bradford C. - MITCHISON, Timothy J. - FISCHER, Eric S. - GRAY, Nathanael S. - HAGGARTY, Stephen J. Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. In ELIFE. ISSN 2050-084X, 2019, vol. 8, no., pp. PANZA, Francesco - IMBIMBO, Bruno P. - LOZUPONE, Madia - GRECO, Antonio - SERIPA, Davide - LOGROSCINO, Giancarlo - DANIELE, Antonio - COLOSIMO, Carlo. Disease-modifying therapies for tauopathies: agents in the pipeline. In EXPERT REVIEW OF NEUROTHERAPEUTICS. ISSN 1473-7175, 2019, vol. 19, no. 5, pp. 397-408. GIAGKOU, Nikolaos - STAMELOU, Maria. Emerging drugs for progressive supranuclear palsy. In EXPERT OPINION ON EMERGING DRUGS. ISSN 1472-8214, 2019, vol. 24, no. 2, pp. 83-92. HOSKIN, Justin L. - SABBAGH, Marwan Noel - AL-HASAN, Yazan - DECOURT, Boris. Tau immunotherapies for Alzheimer's disease. In EXPERT OPINION ON INVESTIGATIONAL DRUGS. ISSN 1354-3784, 2019, vol. 28, no. 6, pp. 545-554. KATSINELOS, Taxiarchis - TUCK, Benjamin J. - MUKADAM, Aamir S. - MCEWAN, William A. The Role of Antibodies and Their Receptors in Protection Against Ordered Protein Assembly in Neurodegeneration. In FRONTIERS IN IMMUNOLOGY. ISSN 1664-3224, 2019, vol. 10, no., pp. MAPHIS, Nicole M. - PEABODY, Julianne - CROSSEY, Erin - JIANG, Shanya - AHMAD, Fadi A. Jamaleddin - ALVAREZ, Maria - MANSOOR, Soiba Khalid - YANEY, Amanda - YANG, Yirong - SILLERUD, Laurel O. - WILSON, Colin M. - SELWYN, Reed - BRIGMAN, Jonathan L. - CANNON, Judy L. - PEABODY, David S. - CHACKERIAN, Bryce - BHASKAR, Kiran. Q beta Virus-like particle-based vaccine induces robust immunity and protects against tauopathy. In NPJ VACCINES. ISSN 2059-0105, 2019, vol. 4, no., pp. ZEIGLER, David F. - GAGE, Emily - ROQUE, Richard - CLEGG, Christopher H. Epitope targeting with self-assembled peptide vaccines. In NPJ VACCINES. ISSN 2059-0105, 2019, vol. 4, no., pp. KOSEOGLU, Emel. New treatment modalities in Alzheimer's disease. In WORLD JOURNAL OF CLINICAL CASES. ISSN 2307-8960, 2019, vol. 7, no. 14, pp. 1764-1774. SILVA, Joana Margarida - RODRIGUES, Sara - SAMPAIO-MARQUES, Belem - GOMES, Patricia - NEVES-CARVALHO, Andreia - DIOLI, Chrysoula - SOARES-CUNHA, Carina - MAZUIK, Brandon F. - TAKASHIMA, Akihiko - LUDOVICO, Paula - WOLOZIN, Benjamin - SOUSA, Nuno - SOTIROPOULOS, Ioannis. Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. In CELL DEATH AND DIFFERENTIATION. ISSN 1350-9047, 2019, vol. 26, no. 8, pp. 1411-1427. LOERA-VALENCIA, R. - CEDAZO-MINGUEZ, A. - KENIGSBERG, P. A. - PAGE, G. - DUARTE, A. - GIUSTI, P. - ZUSSO, M. - ROBERT, P. - FRISONI, G. B. - CATTANEO, A. - ZILLE, M. - BOLTZE, J. - CARTIER, N. - BUEE, L. - JOHANSSON, G. - WINBLAD, B. Current and emerging avenues for Alzheimer's disease drug targets. In JOURNAL OF INTERNAL MEDICINE. ISSN 0954-6820, 2019, vol. 286, no. 4, pp. 398-437. ROESLER, Thomas W. - MARVIAN, Amir Tayaranian - BRENDEL, Matthias - NYKAENEN, Niko-Petteri - HOELLERHAGE, Matthias - SCHWARZ, Sigrid C. - HOPFNER, Franziska - KOEGLSPERGER, Thomas - RESPONDEK, Gesine - SCHWEYER, Kerstin - LEVIN, Johannes - VILLEMAGNE, Victor L. - BARTHEL, Henryk - SABRI, Osama - MUELLER, Ulrich - MEISSNER, Wassilios G. - KOVACS, Gabor G. - HOEGLINGER, Gunter U. Four-repeat tauopathies. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, 2019, vol. 180, no., pp. FLIESSBACH, Klaus - MCCORMICK, Cornelia - KAULENZ, Barbara - SCHNEIDER, Anja. Anti-tau therapies-what can be expected? In NERVENARZT. ISSN 0028-2804, 2019, vol. 90, no. 9, pp. 891-897. MCALARY, Luke - PLOTKIN, Steven S. - CASHMAN, Neil R. Emerging Developments in Targeting Proteotoxicity in Neurodegenerative Diseases. In CNS DRUGS. ISSN 1172-7047, 2019, vol. 33, no. 9, pp. 883-904. DHAKAL, Sudip - KUSHAIRI, Naufal - PHAN, Chia Wei - ADHIKARI, Benu - SABARATNAM, Vikineswary - MACREADIE, Ian. Dietary Polyphenols: A Multifactorial Strategy to Target Alzheimer's Disease. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, vol. 20, no. 20, pp. SELL, Stewart. How vaccines work: immune effector mechanisms and designer vaccines. In EXPERT REVIEW OF VACCINES. ISSN 1476-0584, 2019, vol. 18, no. 10, pp. 993-1015. HOVAKIMYAN, Armine - ANTONYAN, Tatevik - SHABESTARI, Sepideh Kiani - SVYSTUN, Olga - CHAILYAN, Gor - COBURN, Morgan A. - CARLEN-JONES, William - PETRUSHINA, Irina - CHADAREVIAN, Jean Paul - ZAGORSKI, Karen - PETROVSKY, Nikolai - CRIBBS, David H. - AGADJANYAN, Michael G. - GHOCHIKYAN, Anahit - DAVTYAN, Hayk. A MuItiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice. In SCIENTIFIC REPORTS. ISSN 2045-2322, 2019, vol. 9, no., pp. BEAURAIN, Marie - SALABERT, Anne-Sophie - RIBEIRO, Maria Joao - ARLICOT, Nicolas - DAMIER, Philippe - LE JEUNE, Florence - DEMONET, Jean-Francois - PAYOUX, Pierre. Innovative Molecular Imaging for Clinical Research, Therapeutic Stratification, and Nosography in Neuroscience. In FRONTIERS IN MEDICINE, 2019, vol. 6, no., pp. SAYAS, Carmen Laura. Tau-based therapies for Alzheimer's disease: Promising novel neuroprotective approaches. In Neuroprotection in Autism, Schizophrenia and Alzheimer's disease, 2019-10-16, pp. 245-272. WANG, Xiao Zhen - WANG, Rong. The pharmacotherapy and research progress of drugs for Alzheimer's disease. In Chinese Journal of New Drugs. ISSN 10033734, 2019-12-30, 28, 24, pp. 2960-2964. JISKOOT, W. - KERSTEN, G.F.A. - MASTROBATTISTA, E. - SLUTTER, B. Vaccines. IN Pharmaceutical Biotechnology: Fundamentals and Applications, 2019, pp. 282-304. ISBN 978-303000710-2. ZHOU, Qihui - MARELJIC, Nikola - MICHAELSEN, Meike - PARHIZKAR, Samira - HEINDL, Steffanie - NUSCHER, Brigitte - FARNY, Daniel - CZUPPA, Mareike - SCHLUDI, Carina - GRAF, Alexander - KREBS, Stefan - BLUM, Helmut - FEEDERLE, Regina - ROTH, Stefan - HAASS, Christian - ARZBERGER, Thomas - LIESZ, Arthur - EDBAUER, Dieter. Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. In EMBO MOLECULAR MEDICINE. ISSN 1757-4676, 2020, vol. 12, no. 2, pp. COPE, Z.A. - MURAI, T. - RIZZO, S.S.J. Emerging Electroencephalographic Biomarkers to Improve Preclinical to Clinical Translation in Alzheimer's Disease. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, FEB 17 2022, vol. 14. ZHOU, S. - ZHONG, Q. - WANG, Y. - HU, P. - ZHONG, W. - HUANG, C.B. - YU, Z.Q. - DING, C.D. - LIU, H.X. - FU, J.J. Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases. In COORDINATION CHEMISTRY REVIEWS. ISSN 0010-8545, FEB 1 2022, vol. 452. VASSILAKOPOULOU, V. - KARACHALIOU, C.E. - EVANGELOU, A. - ZIKOS, C. - LIVANIOU, E. Peptide-Based Vaccines for Neurodegenerative Diseases: Recent Endeavors and Future Perspectives. In VACCINES. NOV 2021, vol. 9, no. 11. RESPONDEK, G. - KREY, L. - HUBER, M. - PFLUGRAD, H. - WEGNER, F. - HOGLINGER, G.U. Neuroprotective treatment of tauopathies. In NERVENARZT. ISSN 0028-2804, DEC 2021, vol. 92, no. 12, SI, p. 1227-1238. IMBIMBO, B.P. - IPPATI, S. - WATLING, M. - BALDUCCI, C. A critical appraisal of tau-targeting therapies for primary and secondary tauopathies. In ALZHEIMERS & DEMENTIA. ISSN 1552-5260, MAY 2022, vol. 18, no. 5, p. 1008-1037. LIN, P. - SUN, J.Y. - CHENG, Q. - YANG, Y. - CORDATO, D. - GAO, J.Q. The Development of Pharmacological Therapies for Alzheimer's Disease. In NEUROLOGY AND THERAPY. ISSN 2193-8253, DEC 2021, vol. 10, no. 2, p. 609-626. GUPTA, G.L. - SAMANT, N.P. Current druggable targets for therapeutic control of Alzheimer's disease. In CONTEMPORARY CLINICAL TRIALS. ISSN 1551-7144, OCT 2021, vol. 109. STAMELOU, M. - RESPONDEK, G. - GIAGKOU, N. - WHITWELL, J.L. - KOVACS, G.G. - HOGLINGER, G.U. Evolving concepts in progressive supranuclear palsy and other 4-repeat tauopathies. In NATURE REVIEWS NEUROLOGY. ISSN 1759-4758, OCT 2021, vol. 17, no. 10, p. 601-620. WANG, D. - HUANG, X.L. - YAN, L. - ZHOU, L.Q. - YAN, C. - WU, J.H. - SU, Z.D. - HUANG, Y.Q. The Structure Biology of Tau and Clue for Aggregation Inhibitor Design. In PROTEIN JOURNAL. ISSN 1572-3887, OCT 2021, vol. 40, no. 5, p. 656-668. WILSON, D. - LE HERON, C. - ANDERSON, T. Corticobasal syndrome: a practical guide. In PRACTICAL NEUROLOGY. ISSN 1474-7758, AUG 2021, vol. 21, no. 4, p. 276-+. YU, T.W. - LANE, H.Y. - LIN, C.E.H. Novel Therapeutic Approaches for Alzheimer's Disease: An Updated Review. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. AUG 2021, vol. 22, no. 15. PARUMS, D.V. Editorial: Targets for Disease-Modifying Therapies in Alzheimer's Disease, Including Amyloid and Tau Protein. In MEDICAL SCIENCE MONITOR. JUL 26 2021, vol. 27. JI, C.Y. - SIGURDSSON, E.M. Current Status of Clinical Trials on Tau Immunotherapies. In DRUGS. ISSN 0012-6667, JUL 2021, vol. 81, no. 10, p. 1135-1152. MORTADA, I. - FARAH, R. - NABHA, S. - OJCIUS, D.M. - FARES, Y. - ALMAWI, W.Y. - SADIER, N.S. Immunotherapies for Neurodegenerative Diseases. In FRONTIERS IN NEUROLOGY. ISSN 1664-2295, JUN 7 2021, vol. 12. SHAH, E.J. - GURDZIEL, K. - RUDEN, D.M. Sex-Differences in Traumatic Brain Injury in the Absence of Tau in Drosophila. In GENES. JUN 2021, vol. 12, no. 6. ANNADURAI, N. - DE SANCTIS, J.B. - HAJDUCH, M. - DAS, V. Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies. In EXPERIMENTAL NEUROLOGY. ISSN 0014-4886, SEP 2021, vol. 343. YANG, L.X. - QIN, Y. - JIAN, C.D. Screening for Core Genes Related to Pathogenesis of Alzheimer's Disease. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, APR 22 2021, vol. 9. PAYOUX, P. - RANJEVA, J.P. Contributions of PET and MRI imaging in the evaluation of CNS drugs in human neurodegenerative diseases. In THERAPIE. ISSN 0040-5957, MAR-APR 2021, vol. 76, no. 2, p. 121-126. PODDAR, M.K. - BANERJEE, S. - CHAKRABORTY, A. - DUTTA, D. Metabolic disorder in Alzheimer's disease. In METABOLIC BRAIN DISEASE. ISSN 0885-7490, JUN 2021, vol. 36, no. 5, p. 781-813. VISSERS, M.F.J.M. - HEUBERGER, J.A.A.C. - GROENEVELD, G.J. Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. FEB 2021, vol. 22, no. 4. ANGLADA-HUGUET, M. - RODRIGUES, S. - HOCHGRAFE, K. - MANDELKOW, E. - MANDELKOW, E.M. Inhibition of Tau aggregation with BSc3094 reduces Tau and decreases cognitive deficits in rTg4510 mice. In ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS. 2021, vol. 7, no. 1. JI, W.B. - GONG, B.F. - JIN, H. - CHEN, X.H. - LI, P. - CHENG, W.B. - ZHAO, Y.C. - HE, B. - ZHUANG, J.H. - GAO, J. - YIN, Y. Recent Progress Towards Vaccines and Antibody-based Therapies Against Alzheimer's Disease. In MINI-REVIEWS IN MEDICINAL CHEMISTRY. ISSN 1389-5575, 2021, vol. 21, no. 19, p. 3062-3072. WU, Q. - HE, Y. - LUO, X.M. VALUE OF URINE AD-RELATED NEURONAL THREAD PROTEIN COMBINED WITH PTAU PROTEIN DETECTION IN THE EARLY DIAGNOSIS ALZHEIMER DISEASE. In ACTA MEDICA MEDITERRANEA. ISSN 0393-6384, 2021, vol. 37, no. 3, p. 1337-1341. NGUYEN, T.T. - VO, T.K. - VO, G.V. Therapeutic Strategies and Nano-Drug Delivery Applications in Management of Aging Alzheimer's Disease. In REVIEWS ON NEW DRUG TARGETS IN AGE-RELATED DISORDERS, PT II. ISSN 0065-2598, 2021, vol. 1286, p. 183-198. MOEZZI, S.M.I. - MOZAFARI, N. - FAZEL-HOSEINI, S.M. - NADIMI-PARASHKOOHI, S. - ABBASI, H. - ASHRAFI, H. - AZADI, A. Apolipoprotein J in Alzheimer's Disease: Shedding Light on Its Role with Cell Signaling Pathway Perspective and Possible Therapeutic Approaches. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, DEC 16 2020, vol. 11, no. 24, p. 4060-4072. QIAN, M.Y. - ZHANG, Z.T. - CHEN, J.C. Combined mixed Gaussian model with pattern recognition in the automatic diagnosis of Alzheimer's disease. In IET IMAGE PROCESSING. ISSN 1751-9659, DEC 15 2020, vol. 14, no. 15, p. 3698-3704. DI NATALE, C. - LA MANNA, S. - DE BENEDICTIS, I. - BRANDI, P. - MARASCO, D. Perspectives in Peptide-Based Vaccination Strategies for Syndrome Coronavirus 2 Pandemic. In FRONTIERS IN PHARMACOLOGY. DEC 3 2020, vol. 11. SOEDA, Y. - TAKASHIMA, A. New Insights Into Drug Discovery Targeting Tau Protein. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, DEC 3 2020, vol. 13. SILVA, M.C. - HAGGARTY, S.J. Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DEC 2020, vol. 21, no. 23. RABIEE, N. - AHMADI, S. - AFSHARI, R. - KHALAJI, S. - RABIEE, M. - BAGHERZADEH, M. - FATAHI, Y. - DINARVAND, R. - TAHRIRI, M. - TAYEBI, L. - HAMBLIN, M.R. - WEBSTER, T.J. Polymeric Nanoparticles for Nasal Drug Delivery to the Brain: Relevance to Alzheimer's Disease. In ADVANCED THERAPEUTICS. MAR 2021, vol. 4, no. 3. VAZ, M. - SILVESTRE, S. Alzheimer's disease: Recent treatment strategies. In EUROPEAN JOURNAL OF PHARMACOLOGY. ISSN 0014-2999, NOV 15 2020, vol. 887. OAKLEY, S.S. - MAINA, M.B. - MARSHALL, K.E. - AL-HILALY, Y.K. - HARRINGTON, C.R. - WISCHIK, C.M. - SERPELL, L.C. Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target. In FRONTIERS IN NEUROLOGY. ISSN 1664-2295, NOV 12 2020, vol. 11. PLOTKIN, S.S. - CASHMAN, N.R. Passive immunotherapies targeting A beta and tau in Alzheimer's disease. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, OCT 2020, vol. 144. SANDUSKY-BELTRAN, L.A. - SIGURDSSON, E.M. Tau immunotherapies: Lessons learned, current status and future considerations. In NEUROPHARMACOLOGY. ISSN 0028-3908, SEP 15 2020, vol. 175. CLEMEN, R. - BEKESCHUS, S. Oxidatively Modified Proteins: Cause and Control of Diseases. In APPLIED SCIENCES-BASEL. SEP 2020, vol. 10, no. 18. SMEDINGA, M. - DARWEESH, S.K.L. - BLOEM, B.R. - POST, B. - RICHARD, E. Towards early disease modification of Parkinson's disease: a review of lessons learned in the Alzheimer field. In JOURNAL OF NEUROLOGY. ISSN 0340-5354, FEB 2021, vol. 268, no. 2, p. 724-733. IMBIMBO, B.P. - LOZUPONE, M. - WATLING, M. - PANZA, F. Discontinued disease-modifying therapies for Alzheimer's disease: status and future perspectives. In EXPERT OPINION ON INVESTIGATIONAL DRUGS. ISSN 1354-3784, SEP 1 2020, vol. 29, no. 9, p. 919-933. KANIYAPPAN, S. - TEPPER, K. - BIERNAT, J. - CHANDUPATLA, R.R. - HUBSCHMANN, S. - IRSEN, S. - BICHER, S. - KLATT, C. - MANDELKOW, E.M. - MANDELKOW, E. FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments. In MOLECULAR NEURODEGENERATION. JUL 16 2020, vol. 15, no. 1. VANDEVREDE, L. - LJUBENKOV, P.A. - ROJAS, J.C. - WELCH, A.E. - BOXER, A.L. Four-Repeat Tauopathies: Current Management and Future Treatments. In NEUROTHERAPEUTICS. ISSN 1933-7213, OCT 2020, vol. 17, no. 4, SI, p. 1563-1581. VANDEVREDE, L. - BOXER, A.L. - POLYDORO, M. Targeting tau: Clinical trials and novel therapeutic approaches. In NEUROSCIENCE LETTERS. ISSN 0304-3940, JUL 13 2020, vol. 731. NG, P.Y. - CHANG, I.S. - KOH, R.Y. - CHYE, S.M. Recent advances in tau-directed immunotherapy against Alzheimer's disease: an overview of pre-clinical and clinical development. In METABOLIC BRAIN DISEASE. ISSN 0885-7490, OCT 2020, vol. 35, no. 7, p. 1049-1066. PAIS, M. - MARTINEZ, L. - RIBEIRO, O. - LOUREIRO, J. - FERNANDEZ, R. - VALIENGO, L. - CANINEU, P. - STELLA, F. - TALIB, L. - RADANOVIC, M. - FORLENZA, O.V. Early diagnosis and treatment of Alzheimer's disease: new definitions and challenges. In BRAZILIAN JOURNAL OF PSYCHIATRY. ISSN 1516-4446, JUL-AUG 2020, vol. 42, no. 4, p. 431-441. FRANCISTIOVA, L. - BIANCHI, C. - DI LAURO, C. - SEBASTIAN-SERRANO, A. - DE DIEGO-GARCIA, L. - KOBOLAK, J. - DINNYES, A. - DIAZ-HERNANDEZ, M. The Role of P2X7 Receptor in Alzheimer's Disease. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, JUN 3 2020, vol. 13. LOEFFLER, D.A. AMBAR, an Encouraging Alzheimer's Trial That Raises Questions. In FRONTIERS IN NEUROLOGY. ISSN 1664-2295, MAY 29 2020, vol. 11. ROSLER, T.W. - COSTA, M. - HOGLINGER, G.U. Disease-modifying strategies in primary tauopathies. In NEUROPHARMACOLOGY. ISSN 0028-3908, MAY 1 2020, vol. 167. PANZA, F. - LOZUPONE, M. - SERIPA, D. - DANIELE, A. - WATLING, M. - GIANNELLI, G. - IMBIMBO, B.P. Development of disease-modifying drugs for frontotemporal dementia spectrum disorders. In NATURE REVIEWS NEUROLOGY. ISSN 1759-4758, APR 2020, vol. 16, no. 4, p. 213-228. FENEBERG, E. - OTTO, M. Gene-specific treatment approaches in Alzheimer's disease and other tauopathies. In NERVENARZT. ISSN 0028-2804, APR 2020, vol. 91, no. 4, SI, p. 312-317. SAYAS, C.L. Tau-based therapies for Alzheimer's disease: Promising novel neuroprotective approaches. In NEUROPROTECTION IN AUTISM, SCHIZOPHRENIA AND ALZHEIMER'S DISEASE. 2020, p. 245-272. GUEST, P.C. The Impact of New Biomarkers and Drug Targets on Age-Related Disorders. In CLINICAL AND PRECLINICAL MODELS FOR MAXIMIZING HEALTHSPAN: Methods and Protocols. ISSN 1064-3745, 2020, vol. 2138, p. 3-28. SINGH, H. - CHAWLA, V. - BALA, R. - DUREJA, H. Current and Future of Alzheimer's Therapy with the Best Approach. In CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. ISSN 1871-5273, 2020, vol. 19, no. 9, p. 691-697. ZARINI-GAKIYE, E. - AMINI, J. - SANADGOL, N. - VAEZI, G. - PARIVAR, K. Recent Updates in the Alzheimer's Disease Etiopathology and Possible Treatment Approaches: A Narrative Review of Current Clinical Trials. In CURRENT MOLECULAR PHARMACOLOGY. ISSN 1874-4672, 2020, vol. 13, no. 4, p. 273-294. SONG, G. - YANG, H.Q. - SHEN, N. - PHAM, P. - BROWN, B. - LIN, X.Y. - HONG, Y.Z. - SINU, P. - CAI, J.F. - LI, X.P. - LEON, M. - GORDON, M.N. - MORGAN, D. - ZHANG, S. - CAO, C.H. An Immunomodulatory Therapeutic Vaccine Targeting Oligomeric Amyloid-beta. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2020, vol. 77, no. 4, p. 1639-1653. KABIR, M.T. - UDDIN, M.S. - MATHEW, B. - DAS, P.K. - PERVEEN, A. - ASHRAF, G.M. Emerging Promise of Immunotherapy for Alzheimer's Disease: A New Hope for the Development of Alzheimer's Vaccine. In CURRENT TOPICS IN MEDICINAL CHEMISTRY. ISSN 1568-0266, 2020, vol. 20, no. 13, p. 1214-1234. MONTEIRO, K.L.C. - ALCANTARA, M.G.D. - DE AQUINO, T.M. - DA SILVA, E.F. Tau Protein Aggregation in Alzheimer's Disease: Recent Advances in the Development of Novel Therapeutic Agents. In CURRENT PHARMACEUTICAL DESIGN. ISSN 1381-6128, 2020, vol. 26, no. 15, p. 1682-1692. PRENDECKI, M. - KOWALSKA, M. - TOTON, E. - KOZUBSKI, W. Genetic Editing and Pharmacogenetics in Current and Future Therapy of Neurocognitive Disorders. In CURRENT ALZHEIMER RESEARCH. ISSN 1567-2050, 2020, vol. 17, no. 3, p. 238-258. ETTCHETO, M. - BUSQUETS, O. - ESPINOSA-JIMENEZ, T. - VERDAGUER, E. - AULADELL, C. - CAMINS, A. A Chronological Review of Potential Disease-Modifying Therapeutic Strategies for Alzheimer's Disease. In CURRENT PHARMACEUTICAL DESIGN. ISSN 1381-6128, 2020, vol. 26, no. 12, p. 1286-1299. DERRY, P.J. - HEGDE, M.L. - JACKSON, G.R. - KAYED, R. - TOUR, J.M. - TSAI, A.L. - KENT, T.A. Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, JAN 2020, vol. 184. JANOUTOVA, J. - KOVALOVA, M. - AMBROZ, P. - MACHACZKA, O. - ZATLOUKALOA, A. - NEMCEK, K. - MRAZKOVA, E. - KOSTA, O. - SKOLOUDIK, D. - JANOUT, V. Possible prevention of Alzheimer's disease. In CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE. ISSN 1210-7859, 2020, vol. 83, no. 1, p. 28-32. XIE, J.Y. - LIANG, R.R. - WANG, Y.J. - HUANG, J.Y. - CAO, X. - NIU, B. Progress in Target Drug Molecules for Alzheimer's Disease. In CURRENT TOPICS IN MEDICINAL CHEMISTRY. ISSN 1568-0266, 2020, vol. 20, no. 1, p. 4-36. BOXER, A.L. - GOLD, M. - FELDMAN, H. - BOEVE, B.F. - DICKINSON, S.L.J. - FILLIT, H. - HO, C. - PAUL, R. - PEARLMAN, R. - SUTHERLAND, M. - VERMA, A. - ARNERIC, S.P. - ALEXANDER, B.M. - DICKERSON, B.C. - DORSEY, E.R. - GROSSMAN, M. - HUEY, E.D. - IRIZARRY, M.C. - MARKS, W.J. - MASELLIS, M. - MCFARLAND, F. - NIEHOFF, D. - ONYIKE, C.U. - PAGANONI, S. - PANZARA, M.A. - ROCKWOOD, K. - ROHRER, J.D. - ROSEN, H. - SCHUCK, R.N. - SOARES, H.D. - TATTON, N. New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures. In ALZHEIMERS & DEMENTIA. ISSN 1552-5260, JAN 2020, vol. 16, no. 1, p. 131-143. CONGDON, E.E. - JIANG, Y.X. - SIGURDSSON, E.M. Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly. In SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. ISSN 1084-9521, JUN 2022, vol. 126, SI, p. 125-137. ISLAM, M. - SHEN, F.Y. - REGMI, D. - DU, D.G. Therapeutic strategies for tauopathies and drug repurposing as a potential approach. In BIOCHEMICAL PHARMACOLOGY. ISSN 0006-2952, APR 2022, vol. 198. GOLDE, T.E. Disease-Modifying Therapies for Alzheimer's Disease: More Questions than Answers. In NEUROTHERAPEUTICS. ISSN 1933-7213, JAN 2022, vol. 19, no. 1, SI, p. 209-227. Category ADCA - Scientific papers in foreign journals registered in Current Contents Connect with IF (impacted) Category of document (from 2022) V3 - Vedecký výstup publikačnej činnosti z časopisu Type of document článok Year 2017 Registered in WOS Registered in SCOPUS Registered in CCC DOI 10.1016/S1474-4422(16)30331-3 
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rok CC IF IF Q (best) JCR Av Jour IF Perc SJR SJR Q (best) CiteScore A rok vydania rok metriky IF IF Q (best) SJR SJR Q (best) 2017 2016 26.284 Q1 11.788 Q1
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