Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications

Kováčiková, Lucia; Šoltésová Prnová, Marta; Májeková, Magdaléna; Boháč, Andrej; Karasu,  Çimen; Štefek, Milan

doi:https://dx.doi.org/10.3390/molecules26102867

Počet záznamov: 1

Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications

Názov	Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
Autor	Kováčiková Lucia 1983- SAVEXFATO - Ústav experimentálnej farmakológie a toxikológie SAV ^SCOPUS ^ORCID
Spoluautori	Šoltésová Prnová Marta 1986- SAVEXFATO - Ústav experimentálnej farmakológie a toxikológie SAV ^SCOPUS ^ORCID
	Májeková Magdaléna 1958- SAVEXFATO - Ústav experimentálnej farmakológie a toxikológie SAV ^SCOPUS ^RID ^ORCID
	Boháč Andrej 1964-
	Karasu Çimen
	Štefek Milan 1950-2023 SAVEXFATO - Ústav experimentálnej farmakológie a toxikológie SAV ^SCOPUS ^ORCID

Zdroj.dok.	Molecules. Vol. 26, no. 10 (2021), art. no. 2867
Jazyk dok.	eng - angličtina
Krajina	CH - Švajčiarsko
Poznámky	VEGA 1/0670/18, TUBITAK Project No: 215S197
Druh dok.	rozpis článkov z periodík (rbx)
Ohlasy	HRIZI, Asma - CAILLER, Manon - ROMDHANI-YOUNES, Moufida - CARCENAC, Yvan - THIBONNET, Jerome. Synthesis of New Highly Functionalized 1H-Indole-2-carbonitriles via Cross-Coupling Reactions. In MOLECULES, 2021, vol. 26, no. 17, pp.
	BALESTRI, Francesco - MOSCHINI, Roberta - MURA, Umberto - CAPPIELLO, Mario - DEL CORSO, Antonella. In Search of Differential Inhibitors of Aldose Reductase. In BIOMOLECULES, 2022, vol. 12, no. 4, pp. Dostupné na: https://doi.org/10.3390/biom12040485.
	STOIA, Mihaela - OANCEA, Simona. Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness and Trends. In ANTIOXIDANTS, 2022, vol. 11, no. 4, pp. Dostupné na: https://doi.org/10.3390/antiox11040638.
	BALESTRI, Francesco - POLI, Giulio - PIAZZA, Lucia - CAPPIELLO, Mario - MOSCHINI, Roberta - SIGNORE, Giovanni - TUCCINARDI, Tiziano - MURA, Umberto - DEL CORSO, Antonella. Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches. In BIOLOGY-BASEL, 2022, vol. 11, no. 9, pp. Dostupné na: https://doi.org/10.3390/biology11091324.
	KHARYAL, Ankush - RANJAN, Sanjeev - JASWAL, Shalini - PARVEEN, Darakhshan - GUPTA, Ghanshyam Das - THAREJA, Suresh - VERMA, Sant Kumar. Research progress on 2,4-thiazolidinedione and 2-thioxo-4-thiazolidinone analogues as aldose reductase inhibitors. In JOURNAL OF MOLECULAR STRUCTURE, 2022, vol. 1269, no., pp. ISSN 0022-2860. Dostupné na: https://doi.org/10.1016/j.molstruc.2022.133742.
	ZENG, Yancong - ZHENG, Ziyou - YIN, Meili - LI, Jiahao - XU, Jun - TANG, Yinying - ZHANG, Kun - LIU, Zhijun - CHEN, Shijian - SUN, Pinghua - CHEN, Heru. Length and rigidity of the spacer impact on aldose reductase inhibition of the 5F-like ARIs in a dual-occupied mode. In BIOORGANIC CHEMISTRY, 2023, vol. 131, no., pp. ISSN 0045-2068. Dostupné na: https://doi.org/10.1016/j.bioorg.2022.106300.
	ZHANG, C.Y. - GU, L.M. - XIE, H. - LIU, Y. - HUANG, P.R. - ZHANG, J.T. - LUO, D.W. - ZHANG, J.F. Glucose transport, transporters and metabolism in diabetic retinopathy. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, MAR 2024, vol. 1870, no. 3. Dostupné na: https://doi.org/10.1016/j.bbadis.2023.166995.
	WEN, K.M. - CHEN, C. - KONG, W.Y. - GAO, Q.W. - SHI, J. - TANG, X.D. Cooperative Triple Catalysis Enables Deaminative α-Indolmethylation of Carbonyl Compounds with Gramines. In JOURNAL OF ORGANIC CHEMISTRY. ISSN 0022-3263, JAN 8 2024, vol. 89, no. 2, p. 1064-1072. Dostupné na: https://doi.org/10.1021/acs.joc.3c02170.
Kategória	ADCA - Vedecké práce v zahraničných karentovaných časopisoch impaktovaných
Kategória (od 2022)	V3 - Vedecký výstup publikačnej činnosti z časopisu
Typ výstupu	článok
Rok vykazovania	2021
Registrované v	WOS
Registrované v	SCOPUS
Registrované v	CCC
DOI	10.3390/molecules26102867

článok

	Názov súboru	Prístup	Veľkosť	Stiahnuté	Typ	Licence
	Development of Novel Indole‐Based Bifunctional Aldose Reductase Inhibitors.pdf	Prístupný	3.2 MB	4	Vydavateľská verzia

^SCOPUS

^ORCID

Štefek Milan 1950-2023 SAVEXFATO - Ústav experimentálnej farmakológie a toxikológie SAV

^SCOPUS

^ORCID

Zdroj.dok.

Neurotoxicity Research. Vol. 39, no. 3 (2021), p. 588-597

Jazyk dok.

eng - angličtina

Krajina

US - Spojené štáty

Poznámky

TUBITAK project no. 215S197, NIEHS grants R01ES03771, R01ES10563

Druh dok.

rozpis článkov z periodík (rbx)

Ohlasy

URSO, C. J. - ZHOU, Heping. Palmitic Acid Lipotoxicity in Microglia Cells Is Ameliorated by Unsaturated Fatty Acids. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, vol. 22, no. 16, pp. Dostupné na: https://doi.org/10.3390/ijms22169093.

IMRAN, Aqeel - SHEHZAD, Muhammad Tariq - AL ADHAMI, Taha - RAHMAN, Khondaker Miraz - HUSSAIN, Dilawar - ALHARTHY, Rima D. - SHAFIQ, Zahid - IQBAL, Jamshed. Development of coumarin-thiosemicarbazone hybrids as aldose reductase inhibitors: Biological assays, molecular docking, simulation studies and ADME evaluation. In BIOORGANIC CHEMISTRY. ISSN 0045-2068, 2021, vol. 115, no., pp. Dostupné na: https://doi.org/10.1016/j.bioorg.2021.105164.

TASSOPOULOU, Vassiliki-Panagiota - TZARA, Ariadni - KOUROUNAKIS, Angeliki P. Design of Improved Antidiabetic Drugs: A Journey from Single to Multitarget Agents. In CHEMMEDCHEM, 2022, vol. 17, no. 23, pp. ISSN 1860-7179. Dostupné na: https://doi.org/10.1002/cmdc.202200320.

HUANG, Yu-Kai - LIU, Chia-Chun - WANG, Shining - CHENG, Hui-Chun - MEADOWS, Chandler - CHANG, Kun-Che. The Role of Aldose Reductase in Beta-Amyloid-Induced Microglia Activation. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, vol. 23, no. 23, pp. Dostupné na: https://doi.org/10.3390/ijms232315088.

SHARMA, A. - SANJAY - JAISWAL, V. - PARK, M. - LEE, H.J. Biogenic silver NPs alleviate LPS-induced neuroinflammation in a human fetal brain-derived cell line: Molecular switch to the M2 phenotype, modulation of TLR4/MyD88 and Nrf2/HO-1 signaling pathways, and molecular docking analysis. In BIOMATERIALS ADVANCES. MAY 2023, vol. 148. Dostupné na: https://doi.org/10.1016/j.bioadv.2023.213363.

CHEN, H.L. - GUO, Z.C. - SUN, Y.X. - DAI, X.L. The immunometabolic reprogramming of microglia in Alzheimer's disease. In NEUROCHEMISTRY INTERNATIONAL. ISSN 0197-0186, DEC 2023, vol. 171. Dostupné na: https://doi.org/10.1016/j.neuint.2023.105614.

Kategória

ADMA - Vedecké práce v zahraničných impaktovaných časopisoch registrovaných vo WOS Core Collection alebo SCOPUS

Kategória (od 2022)

V3 - Vedecký výstup publikačnej činnosti z časopisu

Typ výstupu

článok

Rok vykazovania

2021

Registrované v

WOS

Registrované v

SCOPUS