Počet záznamov: 1  

ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer's disease

  1. NázovADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer's disease
    Autor Novák Petr    SCOPUS
    Spoluautori Kováčech Branislav    SCOPUS

    		Kontseková Eva    SCOPUS

    		Fialová Ľubica    ORCID

    		Paulenka Ivanovova Natália

    		Hanes Jozef    ORCID

    		Kováč Andrej    SCOPUS

    		Parrák Vojtech

    		Kosoň Peter    SCOPUS

    		Prčina Michal

    		Galba Jaroslav

    		Čente Martin    ORCID

    		Hromádka Tomáš SAVNEIMU - Neuroimunologický ústav SAV

    		Filipčík Peter    ORCID

    		Piešťanský Juraj

    		Novák Michal    SCOPUS

    		Žilka Norbert    SCOPUS

    Spoluautori Katina Stanislav Schmidt Reinhold Scheltens Philip Ropele Stefan Kramberger Milica Smisek Miroslav Stevens Eva Sutovsky Stanislav Samcova Maria Prenn-Gologranc Carmen Sivak Roman Froelich Lutz Fresser Michal Rakusa Martin Harrison John Hort Jakub Otto Markus Tosun Duygu Ondrus Matej Winblad Bengt
    Zdroj.dok. Nature Aging. Vol. 1 (2021), p. 521-534
    Jazyk dok.eng - angličtina
    Druh dok.rozpis článkov z periodík (rbx)
    OhlasyGALASKO, D. Active immunization in Alzheimer's disease. In NATURE AGING. JUN 2021, vol. 1, no. 6, p. 493-495. Dostupné na: https://doi.org/10.1038/s43587-021-00076-w.
    KITOKA, K. - SKRABANA, R. - GASPARIK, N. - HRITZ, J. - JAUDZEMS, K. NMR Studies of Tau Protein in Tauopathies. In FRONTIERS IN MOLECULAR BIOSCIENCES. NOV 11 2021, vol. 8. Dostupné na: https://doi.org/10.3389/fmolb.2021.761227.
    [ANONYMOUS]. Tinkerbell and the great fairy rescue. In NEUROSCIENTIST. ISSN 1073-8584, OCT 2021, vol. 27, no. 5, p. 451-452. Dostupné na: https://doi.org/10.1177/10738584211041574.
    FRöLICH, L. - HAUSNER, L. Disease-modifying treatment approaches for Alzheimer's disease. In NERVENARZT. ISSN 0028-2804, DEC 2021, vol. 92, no. 12, SI, p. 1239-1248. Dostupné na: https://doi.org/10.1007/s00115-021-01222-w.
    HöGLINGER, G.U. Neuropathology of progressive supranuclear palsy after treatment with tilavonemab reply. In LANCET NEUROLOGY. ISSN 1474-4422, OCT 2021, vol. 20, no. 10, p. 787-788. Dostupné na: https://doi.org/10.1016/S1474-4422(21)00284-2.
    IQBAL, K. Thinking beyond the Aducanumab Controversy. In ANNALS OF NEUROLOGY. ISSN 0364-5134, DEC 2021, vol. 90, no. 6, p. 1003-1004. Dostupné na: https://doi.org/10.1002/ana.26252.
    TASHIMA, T. Delivery of Intravenously Administered Antibodies Targeting Alzheimer's Disease-Relevant Tau Species into the Brain Based on Receptor-Mediated Transcytosis. In PHARMACEUTICS. FEB 2022, vol. 14, no. 2. Dostupné na: https://doi.org/10.3390/pharmaceutics14020411.
    GONG, C.X. - DAI, C.L. - LIU, F. - IQBAL, K. Multi-Targets: An Unconventional Drug Development Strategy for Alzheimer's Disease. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, FEB 9 2022, vol. 14. Dostupné na: https://doi.org/10.3389/fnagi.2022.837649.
    GAUTHIER, S. - BOXER, A. - KNOPMAN, D. - SIMS, J. - DOODY, R. - AISEN, P. - IWATSUBO, T. - BATEMAN, R. - VELLAS, B. Therapeutic Targets for Alzheimer's Disease: Amyloid Vs. Non-Amyloid. Where Does Consensus Lie Today? An CTAD Task Force Report. In JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE. ISSN 2274-5807, APR 2022, vol. 9, no. 2, p. 231-235. Dostupné na: https://doi.org/10.14283/jpad.2022.29.
    SONG, C.H. - SHI, J.Y. - ZHANG, P.A. - ZHANG, Y.F. - XU, J.R. - ZHAO, L.X. - ZHANG, R. - WANG, H. - CHEN, H.Z.A. Immunotherapy for Alzheimer's disease: targeting β-amyloid and beyond. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, MAR 18 2022, vol. 11, no. 1. Dostupné na: https://doi.org/10.1186/s40035-022-00292-3.
    KARIMI, N. - CATAK, F.B. - ARSLAN, E. - SAGHAZADEH, A. - REZAEI, N. Tau immunotherapy in Alzheimer?s disease and progressive supranuclear palsy. In INTERNATIONAL IMMUNOPHARMACOLOGY. ISSN 1567-5769, DEC 2022, vol. 113, B. Dostupné na: https://doi.org/10.1016/j.intimp.2022.109445.
    ZHANG, Y. - WU, K.M. - YANG, L. - DONG, Q. - YU, J.T. Tauopathies: new perspectives and challenges. In MOLECULAR NEURODEGENERATION. APR 7 2022, vol. 17, no. 1. Dostupné na: https://doi.org/10.1186/s13024-022-00533-z.
    GRIMMER, T. Therapy Developments in Alzheimer's Disease. In FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE. ISSN 0720-4299, JUL 2022, vol. 90, no. 07/08, p. 352-360. Dostupné na: https://doi.org/10.1055/a-1802-4837.
    VILLAIN, N. Therapeutic news in Alzheimer?s disease: Soon a disease-modifying therapy?. In REVUE NEUROLOGIQUE. ISSN 0035-3787, MAY 2022, vol. 178, no. 5, SI, p. 437-440. Dostupné na: https://doi.org/10.1016/j.neurol.2022.02.456.
    NASCIMENTO, A.L.C.S. - FERNANDES, R.P. - CARVALHO, A.C.S. - FRIGIERI, I. - ALVES, R.C. - CHORILLI, M. Insights for Alzheimer?s disease pharmacotherapy and current clinical trials. In NEUROCHEMISTRY INTERNATIONAL. ISSN 0197-0186, OCT 2022, vol. 159. Dostupné na: https://doi.org/10.1016/j.neuint.2022.105401.
    RAMESH, M. - GOVINDARAJU, T. Multipronged diagnostic and therapeutic strategies for Alzheimer's disease. In CHEMICAL SCIENCE. ISSN 2041-6520, NOV 30 2022, vol. 13, no. 46, p. 13657-13689. Dostupné na: https://doi.org/10.1039/d2sc03932j.
    BURNS, S. - SELMAN, A. - SEHAR, U. - RAWAT, P. - REDDY, A.P. - REDDY, P.H. Therapeutics of Alzheimer's Disease: Recent Developments. In ANTIOXIDANTS. DEC 2022, vol. 11, no. 12. Dostupné na: https://doi.org/10.3390/antiox11122402.
    IMBIMBO, B.P. - IPPATI, S. - WATLING, M. - BALDUCCI, C. A critical appraisal of tau-targeting therapies for primary and secondary tauopathies. In ALZHEIMERS & DEMENTIA. ISSN 1552-5260, MAY 2022, vol. 18, no. 5, p. 1008-1037. Dostupné na: https://doi.org/10.1002/alz.12453.
    KANTARCI, K. 2021 marks a new era for Alzheimer's therapeutics. In LANCET NEUROLOGY. ISSN 1474-4422, JAN 2022, vol. 21, no. 1, p. 3-4. Dostupné na: https://doi.org/10.1016/S1474-4422(21)00412-9.
    CAO, L. - KONG, Y.Y. - JI, B. - REN, Y.T. - GUAN, Y.H. - NI, R.Q. Positron Emission Tomography in Animal Models of Tauopathies. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, JAN 10 2022, vol. 13. Dostupné na: https://doi.org/10.3389/fnagi.2021.761913.
    NI, R.Q. Magnetic Resonance Imaging in Tauopathy Animal Models. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, JAN 25 2022, vol. 13. Dostupné na: https://doi.org/10.3389/fnagi.2021.791679.
    ISLAM, M. - SHEN, F.Y. - REGMI, D. - DU, D.G. Therapeutic strategies for tauopathies and drug repurposing as a potential approach. In BIOCHEMICAL PHARMACOLOGY. ISSN 0006-2952, APR 2022, vol. 198. Dostupné na: https://doi.org/10.1016/j.bcp.2022.114979.
    CONGDON, E.E. - JIANG, Y.X. - SIGURDSSON, E.M. Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly. In SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. ISSN 1084-9521, JUN 2022, vol. 126, SI, p. 125-137. Dostupné na: https://doi.org/10.1016/j.semcdb.2021.12.002.
    VILLAIN, N. Therapeutic news in Alzheimer's disease: soon a disease-modifying therapy?. In GERIATRIE ET PSYCHOLOGIE NEUROPSYCHIATRIE DE VIEILLISSEMENT. ISSN 2115-8789, JUN 2022, vol. 20, no. 2, p. 256-260. Dostupné na: https://doi.org/10.1684/pnv.2022.1042.
    BILGEL, M. - WONG, D.F. - MOGHEKAR, A.R. - FERRUCCI, L. - RESNICK, S.M. Causal links among amyloid, tau, and neurodegeneration. In BRAIN COMMUNICATIONS. JUL 4 2022, vol. 4, no. 4. Dostupné na: https://doi.org/10.1093/braincomms/fcac193.
    WINEK, K. - TZUR, Y. - SOREQ, H. Biological underpinnings of sex differences in neurological disorders. In SEX AND GENDER DIFFERENCES IN NEUROLOGICAL DISEASE, VOL. 164. ISSN 0074-7742, 2022, p. 27-67. Dostupné na: https://doi.org/10.1016/bs.irn.2022.06.009.
    ALIPOUR, M. - TEBIANIAN, M. - TOFIGH, N. - TAHERI, R.S. - MOUSAVI, S.A. - NASERI, A. - AHMADI, A. - MUNAWAR, N. - SHAHPASAND, K. Active immunotherapy against pathogenici Cis/i pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models. In NEUROPEPTIDES. ISSN 0143-4179, DEC 2022, vol. 96. Dostupné na: https://doi.org/10.1016/j.npep.2022.102285.
    HOVAKIMYAN, A. - ZAGORSKI, K. - CHAILYAN, G. - ANTONYAN, T. - MELIKYAN, L. - PETRUSHINA, I. - BATT, D.G. - KING, O. - GHAZARYAN, M. - DONTHI, A. - FOOSE, C. - PETROVSKY, N. - CRIBBS, D.H. - AGADJANYAN, M.G. - GHOCHIKYAN, A. Immunogenicity of MultiTEP platform technology-based Tau vaccine in non-human primates. In NPJ VACCINES. OCT 12 2022, vol. 7, no. 1. Dostupné na: https://doi.org/10.1038/s41541-022-00544-3.
    PARROCHA, C.M.T. - NOWICK, J.S. Current peptide vaccine and immunotherapy approaches against Alzheimer's disease. In PEPTIDE SCIENCE. ISSN 2475-8817, JAN 2023, vol. 115, no. 1. Dostupné na: https://doi.org/10.1002/pep2.24289.
    MCFALL-BOEGEMAN, Hunter Sean. Investigations into the Virus-Like Particle Bacteriophage Qβ as a Carrier Platform in Conjugate Vaccines Against Cancer and Alzheimer’s Disease. Jan 01 2022.
    KLEINOVA, L. - CERMAN, J. - HLAVKA, J. - HORT, J. New pharmacological options in the treatment of Alzheimer's disease. In CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE. ISSN 1210-7859, 2022, vol. 85, no. 6, p. 462-469. Dostupné na: https://doi.org/10.48095/cccsnn2022462.
    KategóriaADMB - Vedecké práce v zahraničných neimpaktovaných časopisoch registrovaných vo WOS Core Collection alebo SCOPUS
    Kategória (od 2022)V3 - Vedecký výstup publikačnej činnosti z časopisu
    Typ výstupučlánok
    Rok vykazovania2021
    Registrované vWOS
    Registrované vSCOPUS
    DOI 10.1038/s43587-021-00070-2
    článok

    článok

    Názov súboruPrístupVeľkosťStiahnutéTypLicence
    ADAMANT a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer's disease.pdfPrístupný16.6 MB7Vydavateľská verzia
    rokCCIFIF Q (best)JCR Av Jour IF PercSJRSJR Q (best)CiteScore
    N
    rok vydaniarok metrikyIFIF Q (best)SJRSJR Q (best)
    2021
Počet záznamov: 1  

  Tieto stránky využívajú súbory cookies, ktoré uľahčujú ich prezeranie. Ďalšie informácie o tom ako používame cookies.

Prijať všetkoNastavenieOdmietnuť všetko