Počet záznamov: 1  

Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma

  1. NázovPrognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma
    Autor Chia S.K.
    Spoluautori Wykoff Charles C.

    Watson P.H.

    Leek R.

    Turley H.

    Pastorek Jaromír 1957- SAVVIR - Virologický ústav SAV

    Cox G.J.

    Ratcliffe P.

    Harris Adrian L.

    Zdroj.dok. Journal of Clinical Oncology. Vol.19 (2001), p. 3660-3668
    Jazyk dok.eng - angličtina
    Druh dok.rozpis článkov z periodík (rbx)
    OhlasyToi, M., Bando, Y., Saji, S., Matsumoto, T. Tumor angiogenesis and hypoxia Biotherapy 15 (6), pp. 663-668 , 2001
    Ruibal Morell, A. Genes and breast cancer: Its clinical interest | [Genes y cáncer de mama. Interés clínico] Oncologia 24 (8), pp. 20-34 , 2001
    Williams, K.J., Cowen, R.L., Stratford, I.J. Tumour hypoxia - Therapeutic considerations Breast Cancer Research 3 (5), pp. 328-331 ,2001
    Coleman CN, Mitchell JB, Camphausen K Tumor hypoxia: chicken, egg, or a piece of the farm? JOURNAL OF CLINICAL ONCOLOGY Volume: 20 Issue: 3 Pages: 610-615 Published: FEB 1 2002
    Supuran CT, Scozzafava A Applications of carbonic anhydrase inhibitors and activators in therapy EXPERT OPINION ON THERAPEUTIC PATENTS Volume: 12 Issue: 2 Pages: 217-242 Published: FEB 2002
    Chiang WL, Chu SC, Yang SS, Li MC, Lai JC, Yang SF, Chiou HL, Hsieh YS The aberrant expression of cytosolic carbonic anhydrase and its clinical significance in human non-small cell lung cancer CANCER LETTERS Volume: 188 Issue: 1-2 Pages: 199-205 Published: DEC 15 2002
    Kaanders JHAM, Wijffels KIEM, Marres HAM, Ljungkvist ASE, Pop LAM, van den Hoogen FJA, de Wilde PCM, Bussink J, Raleigh JA, van der Kogel AJ Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer CANCER RESEARCH Volume: 62 Issue: 23 Pages: 7066-7074 Published: DEC 1 2002
    Hedley, D., Pintilie, M., Woo, J., Morrison, A., Birle, D., Fyles, A., Milosevic, M., Hill, R Carbonic Anhydrase IX Expression, Hypoxia, and Prognosis in Patients with Uterine Cervical Carcinomas Clinical Cancer Research 9 (15), pp. 5666-5674 , 2003
    Závada, J., Závadová, Z., Zat'ovičová, M., Hyršl, L., Kawaciuk, I. Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients British Journal of Cancer 89 (6), pp. 1067-1071 , 2003
    Bos R, van der Groep P, Greijer AE, Shvarts A, Meijer S, Pinedo HM, Semenza GL, van Diest PJ, van der Wall E Levels of hypoxia-inducible factor-1 alpha independently predict prognosis in patients with lymph node negative breast carcinoma CANCER Volume: 97 Issue: 6 Pages: 1573-1581 Published: MAR 15 2003
    Metz S, Daldrup-Link HE, Richter T, Rath C, Ebert W, Settles M, Rummeny EJ, Link TM, Piert M Detection and quantification of breast tumor necrosis with MR imaging: Value of the necrosis-avid contrast agent Gadophrin-3 ACADEMIC RADIOLOGY Volume: 10 Issue: 5 Pages: 484-490 Published: MAY 2003
    Denham JW, Steigler A, Kilmurray J, Wratten C, Burmeister B, Lamb DS, Joseph D, Delaney G, Christie D, Jamieson G, Smithers BM, Ackland S, Walpole E Relapse patterns after chemo-radiation for carcinoma of the oesophagus CLINICAL ONCOLOGY Volume: 15 Issue: 3 Pages: 98-108 Published: MAY 2003
    Scozzafava A, Owa T, Mastrolorenzo A, Supuran CT Anticancer and antiviral sulfonamides CURRENT MEDICINAL CHEMISTRY Volume: 10 Issue: 11 Pages: 925-953 Published: JUN 2003
    Le QT, Kovacs MS, Dorie MJ, Koong A, Terris DJ, Pinto HA, Goffinet DR, Nowels K, Bloch D, Brown JM Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 56 Issue: 2 Pages: 375-383 Published: JUN 1 2003
    Winum JY, Vullo D, Casini A, Montero JL, Scozzafava A, Supuran CT Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors JOURNAL OF MEDICINAL CHEMISTRY Volume: 46 Issue: 11 Pages: 2197-2204 Published: MAY 22 2003
    Colpaert CG, Vermeulen PB, van Beest P, Soubry A, Goovaerts G, Dirix LY, Harris AL, Van Marck EA Cutaneous breast cancer deposits show distinct growth patterns with different degrees of angiogenesis, hypoxia and fibrin deposition HISTOPATHOLOGY Volume: 42 Issue: 6 Pages: 530-540 Published: JUN 2003
    Bussink J, Kaanders JHAM, van der Kogel AJ Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers RADIOTHERAPY AND ONCOLOGY Volume: 67 Issue: 1 Pages: 3-15 Published: APR 2003
    Evans SM, Koch CJ Prognostic significance of tumor oxygenation in humans CANCER LETTERS Volume: 195 Issue: 1 Pages: 1-16 Published: MAY 30 2003
    Span PN, Bussink J, Manders P, Beex LVAM, Sweep CGJ Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: association with treatment outcome BRITISH JOURNAL OF CANCER Volume: 89 Issue: 2 Pages: 271-276 Published: JUL 21 2003
    Kronblad A, Helczynska K, Nielsen NH, Pahlman E, Emdin S, Pahlman S, Landberg G Regional cyclin D1 overexpression or hypoxia correlate inversely with heterogeneous oestrogen receptor-alpha expression in human breast cancer IN VIVO Volume: 17 Issue: 4 Pages: 311-318 Published: JUL-AUG 2003
    Tomes L, Emberley E, Niu YL, Troup S, Pastorek J, Strange K, Harris A, Watson PH Necrosis and hypoxia in invasive breast carcinoma BREAST CANCER RESEARCH AND TREATMENT Volume: 81 Issue: 1 Pages: 61-69 Published: SEP 2003
    Kuo WH, Chiang WL, Yang SF, Yeh KT, Yeh CM, Hsieh YS, Chu SC The differential expression of cytosolic carbonic anhydrase in human hepatocellular carcinoma LIFE SCIENCES Volume: 73 Issue: 17 Pages: 2211-2223 Published: SEP 12 2003
    Hoskin PJ, Sibtain A, Daley FM, Wilson GD GLUTI and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON BRITISH JOURNAL OF CANCER Volume: 89 Issue: 7 Pages: 1290-1297 Published: OCT 6 2003
    Aquino-Parsons C, Ries CR, Minchinton AI, D'yachkova Y The effect of deep inspiration breath-hold on tumour oxygenation CLINICAL ONCOLOGY Volume: 15 Issue: 7 Pages: 386-393 Published: OCT 2003
    Blackwell KL, Kirkpatrick JP, Snyder SA, Broadwater G, Farrell F, Jolliffe L, Brizel DM, Dewhirst MW Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin CANCER RESEARCH Volume: 63 Issue: 19 Pages: 6162-6165 Published: OCT 1 2003
    Pantuck AJ, Zeng G, Belldegrun AS, Figlin RA Pathobiology, prognosis, and targeted therapy for renal cell carcinoma: Exploiting the hypoxia-induced pathway : CLINICAL CANCER RESEARCH Volume: 9 Issue: 13 Pages: 4641-4652 Published: OCT 15 2003
    Bando H, Toi M, Kitada K, Koike M Genes commonly upregulated by hypoxia in human breast cancer cells MCF-7 and MDA-MB-231 BIOMEDICINE & PHARMACOTHERAPY Volume: 57 Issue: 8 Pages: 333-340 Published: OCT 2003
    Supuran, C.T., Vullo, D., Manole, G., Casini, A., Scozzafava, A. Designing of novel carbonic anhydrase inhibitors and activators Current Medicinal Chemistry: Cardiovascular and Hematological Agents 2 (1), pp. 49-68 , 2004
    Cooper, C., Liu, G.-Y., Niu, Y.-L., Santos, S., Murphy, L.C., Watson, P. Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor ? in human breast carcinoma Clinical Cancer Research 10 (24), pp. 8720-8727 , 2004
    Makretsov, N.A.a , Huntsman, D.G.a , Nielsen, T.O.a , Yorida, E.a , Peacock, M.a , Cheang, M.C.U.a , Dunn, S.E.b , Hayes, M.c , Van De Rijn, M.e , Bajdik, C.d , Gilks, C.B. Hierarchical clustering analysis of tissue microarray immunostaining data identifies prognostically significant groups of breast carcinoma Clinical Cancer Research 10 (18 I), pp. 6143-6151 , 2004
    Supuran CT, Casini A, Mastrolorenzo A, Scozzafava A MINI-REVIEWS IN MEDICINAL CHEMISTRY 4 (6): 625-632 AUG 2004
    Dewhirst MW, Richardson R, Cardenas-Navia I, Cao YT HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA 18 (5): 973-+ OCT 2004
    Miller KD, Dul CL HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA 18 (5): 1071+ OCT 2004
    Makretsov NA, Huntsman DG, Nielsen TO, Yorida E, Peacock M, Cheang MCU, Dunn SE, Hayes M, van de Rijn M, Bajdik C, Gilks CB CLINICAL CANCER RESEARCH 10 (18): 6143-6151 Part 1, SEP 15 2004
    Harima Y, Togashi A, Horikoshi K, Imamura M, Sougawa M, Sawada S, Tsunoda T, Nakamura Y, Katagiri T INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 60 (1): 237-248 SEP 1 2004
    van Laarhoven HWM, Bussink J, Lok J, Punt CJA, Heerschap A, van der Kogel AJ INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 60 (1): 310-321 SEP 1 2004
    Leo C, Giaccia AJ, Denko NC SEMINARS IN RADIATION ONCOLOGY 14 (3): 207-214 JUL 2004
    Maseide K, Kandel RA, Bell RS, Catton CN, O'Sullivan B, Wunder JS, Pintilie M, Hedley D, Hill RP CLINICAL CANCER RESEARCH 10 (13): 4464-4471 JUL 1 2004
    Le QT, Denko NC, Giaccia AJ CANCER AND METASTASIS REVIEWS 23 (3-4): 293-310 AUG-DEC 2004
    Jubb AM, Pham TQ, Hanby AM, Frantz GD, Peale FV, Wu TD, Koeppen HW, Hillan KJ JOURNAL OF CLINICAL PATHOLOGY 57 (5): 504-512 MAY 1 2004
    Hopfl G, Ogunshola O, Gassmann M AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 286 (4): R608-R623 APR 1 2004
    Kurebayashi, J. Resistance to endocrine therapy in breast cancer Cancer Chemotherapy and Pharmacology 56 (SUPPL. 7), pp. s39-s46, 2005
    Burmeister, B.H., Walpole, E.T., Burmeister, E.A., Thomas, J., Thomson, D.B., Harvey, J.A., Smithers, B.M., Gotley, D.C. Feasibility of chemoradiation therapy with protracted infusion of 5-fluorouracil for esophageal cancer patients not suitable for cisplatin International Journal of Clinical Oncology 10 (4), pp. 256-261 , 2005
    Mayer A, Hockel M, Vaupel P Carbonic anhydrase IX expression and tumor oxygenation status do not correlate at the microregional level in locally-advanced cancers of the uterine cervix CLINICAL CANCER RESEARCH 11 (20): 7220-7225 OCT 15 2005
    Innocenti A, Villar R, Martinez-Merino V, Gll MJ, Scozzafava A, Vullo D, Supuran CT Carbonic anhydrase inhibitors: Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 15 (21): 4872-4876 NOV 1 2005
    Kuijper A, van der Groep P, van der Wall E, van Diest PJ Expression of hypoxia-inducible factor 1 alpha and its downstream targets in fibroepithelial tumors of the breast BREAST CANCER RESEARCH 7 (5): R808-R818 2005
    Vaupel P, Mayer A, Briest S, Hockel M Hypoxia in breast cancer: Role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion OXYGEN TRANSPORT TO TISSUE XXVI ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 566: 333-342 2005
    Lam JS, Leppert JT, Belldegrun AS, Figlin RA Novel approaches in the therapy of metastatic renal cell carcinoma WORLD JOURNAL OF UROLOGY 23 (3): 202-212 JUL 2005
    Kummola L, Hamalainen JM, Kivela J, Kivela AJ, Saarnio J, Karttunen T, Parkkila S Expression of a novel carbonic anhydrase, CA XIII, in normal and neoplastic colorectal mucosa BMC CANCER 5: Art. No. 41 APR 18 2005
    Zavadova Z, Zavada J Carbonic anhydrase IX (CA IX) mediates tumor cell interactions with microenvironment ONCOLOGY REPORTS 13 (5): 977-982 MAY 2005
    Vordermark D, Kaffer A, Riedl S, Katzer A, Flentje M Characterization of carbonic anhydrase IX (CA IX) as an endogenous marker of chronic hypoxia in live human tumor cells INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 61 (4): 1197-1207 MAR 15 2005
    Schneider BP, Miller KD Angiogenesis of breast cancer JOURNAL OF CLINICAL ONCOLOGY 23 (8): 1782-1790 MAR 10 2005
    Stone JF, Parker R, Gilks CB, Stanbridge EJ, Liao SY, Aquino-Parsons C Intratumoral oxygenation of invasive squamous cell carcimoma of the vulva is not correlated with regional lymph node metastasis EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 26 (1): 31-35 2005
    Hoogsteen IJ, Marres HAM, Wijffels KIEM, Rijken PFJW, Peters JPW, van den Hoogen FJA, Oosterwijk E, van der Kogel AJ, Kaanders JHAM Colocalization of carbonic anhydrase 9 expression and cell proliferation in human head and neck squamous cell carcinoma CLINICAL CANCER RESEARCH 11 (1): 97-106 JAN 1 2005
    Van Laarhoven, H.W.M.a e , Kaanders, J.H.A.M.b , Lok, J.b , Peeters, W.J.M.b , Rijken, P.F.J.W.b , Wiering, B.c , Ruers, T.J.M.c , Punt, C.J.A.a , Heerschap, A.d , Van Der Kogel, A.J Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer International Journal of Radiation Oncology Biology Physics 64 (2), pp. 473-482 , 2006
    Chaudarya, N., Hill, R.P. Hypoxia and metastasis in breast cancer Breast Disease 26 (1), pp. 55-64 , 2006
    Sivridis, E., Giatromanolaki, A., Galazios, G., Koukourakis, M.I. Node-related factors and survival in node-positive breast carcinomas Breast 15 (3), pp. 382-389 , 2006
    Saczewski F (Saczewski, Franciszek), Innocenti A (Innocenti, Alessio), Brzozowski Z (Brzozowski, Zdzislaw), Slawinski J (Slawinski, Jaroslaw), Pomarnacka E (Pomarnacka, Elzbieta), Kornicka A (Kornicka, Anita), Scozzafava A (Scozzafava, Andrea), Supuran CT (Supuran, Claudiu T.) Carbonic anhydrase inhibitors. Selective inhibition of human tumor-associated isozymes IX and XII and cytosolic isozymes I and II with some substituted-2-mercapto-benzenesulfonamides JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 21 (5): 563-568 OCT 2006
    Kon-No H (Kon-no, Hidehiro), Ishii G (Ishii, Genichiro), Nagai K (Nagai, Kanji), Yoshida J (Yoshida, Junji), Nishimura M (Nishimura, Mitsuyo), Nara M (Nara, Michiya), Fujii T (Fujii, Tomoki), Murata Y (Murata, Yukinori), Miyamoto H (Miyamoto, Hideaki), Ochiai A (Ochiai, Atsushi) Carbonic anhydrase IX expression is associated with tumor progression and a poor prognosis of lung adenocarcinoma LUNG CANCER 54 (3): 409-418 DEC 2006
    Brennan DJ (Brennan, Donal J.), Jirstrom K (Jirstrom, Karin), Kronblad A (Kronblad, Asa), Millikan RC (Millikan, Robert C.), Landberg G (Landberg, Goran), Duffy MJ (Duffy, Michael J.), Ryden L (Ryden, Lisa), Gallagher WM (Gallagher, William M.), O'Brien SL (O'Brien, Sallyann L.) CA IX is an independent prognostic marker in premenopausal breast cancer patients with one to three positive lymph nodes and a putative marker of radiation resistance CLINICAL CANCER RESEARCH 12 (21): 6421-6431 NOV 1 2006
    Varker KA (Varker, Kimberly A.), Kondadasula V (Kondadasula, Vidya), Go MR (Go, Michael R.), Lesinski GB (Lesinski, Gregory B.), Ghosh-Berkebile R (Ghosh-Berkebile, Rupa), Lehman A (Lehman, Amy), Monk JP (Monk, J. Paul), Olencki T (Olencki, Thomas), Kendra K (Kendra, Kari), Carson WE (Carson, William E., III) Multiparametric flow cytometric analysis of signal transducer and activator of transcription 5 phosphorylation in immune cell subsets in vitro and following interieukin-2 immunotherapy CLINICAL CANCER RESEARCH 12 (19): 5850-5858 OCT 1 2006
    Atkin G (Atkin, G.), Taylor NJ (Taylor, N. J.), Daley FM (Daley, F. M.), Stirling JJ (Stirling, J. J.), Richman P (Richman, P.), Glynne-Jones R (Glynne-Jones, R.), d'Arcy JA (d'Arcy, J. A.), Collins DJ (Collins, D. J.), Padhani AR (Padhani, A. R.) Dynamic contrast-enhanced magnetic resonance imaging is a poor measure of rectal cancer angiogenesis BRITISH JOURNAL OF SURGERY 93 (8): 992-1000 AUG 2006
    Leo C, Horn LC, Hockel M Hypoxia and expression of the proapoptotic regulator BNIP3 in cervical cancer INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 16 (3): 1314-1320 MAY-JUN 2006
    Thiry A, Ledecq M, Cecchi A, Dogne JM, Wouters J, Supuran CT, Masereel B Indanesulfonamides as carbonic anhydrase inhibitors. Toward structure-based design of selective inhibitors of the tumor-associated isozyme CA IX JOURNAL OF MEDICINAL CHEMISTRY 49 (9): 2743-2749 MAY 4 2006
    Chi JT, Wang Z, Nuyten DSA, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Borresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers PLOS MEDICINE 3 (3): 395-409 MAR 2006
    Vullo D, Steffansen B, Brodin B, Supuran CT, Scozzafava A, Nielsen CU Carbonic anhydrase inhibitors: Transepithelial transport of thioureido sulfonamide inhibitors of the cancer-associated isozyme IX is dependent on efflux transporters BIOORGANIC & MEDICINAL CHEMISTRY 14 (7): 2418-2427 APR 1 2006
    van Laarhoven HWM, Kaanders JHAM, Lok J, Peeters WJM, Rijken PFJW, Wiering B, Ruers TJM, Punt CJA, Heerschap A, van der Kogel AJ Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 64 (2): 473-482 FEB 1 2006
    Eui, J.M., Brizel, D.M., Chi, J.-T.A., Dewhirst, M.W. The potential role of intrinsic hypoxia markers as prognostic variables in cancer Antioxidants and Redox Signaling 9 (8), pp. 1237-1294 , 2007
    Nuti, E., Orlandini, E., Nencetti, S., Rossello, A., Innocenti, A., Scozzafava, A., Supuran, C.T. Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates Bioorganic and Medicinal Chemistry 15 (6), pp. 2298-2311 , 2007
    Westwell, A.D. Novel antitumour agents: indanesulfonamides as selective inhibitors of the tumour-associated isozyme carbonic anhydrase IX Drug Discovery Today 12 (1-2), pp. 100 , 2007
    Brennan, D.J., Kelly, C., Rexhepaj, E., Dervan, P.A., Duffy, M.J., Gallagher, W.M Contribution of DNA and tissue microarray technology to the identification and validation of biomarkers and personalised medicine in breast cancer Cancer Genomics and Proteomics 4 (3), pp. 121-134 , 2007
    Supuran, C.T Therapeutic applications of the carbonic anhydrase inhibitors Therapy 4 (3), pp. 355-378 , 2007
    Fumoleau, P (Fumoleau, Pierre); Coudert, B (Coudert, Bruno); Mayer, F (Mayer, Francoise); Isambert, N (Isambert, Nicolas); Favier, L (Favier, Laure); Ferrant, E (Ferrant, Emmanuelle) Angiogenesis targeting in breast cancer BULLETIN DU CANCER, 94: F199-F206 Suppl. 7 SEP 2007
    Iakovlev, VV (Iakovlev, Vladimir V.); Pintilie, M (Pintilie, Melania); Morrison, A (Morrison, Andrew); Fyles, AW (Fyles, Anthony W.); Hill, RP (Hill, Richard P.); Hedley, DW (Hedley, David W.) Effect of distributional heterogeneity on the analysis of tumor hypoxia based on carbonic anhydrase IX LABORATORY INVESTIGATION, 87 (12): 1206-1217 DEC 2007
    Van den Eynden, GG (Van den Eynden, G. G.); Colpaert, CG (Colpaert, C. G.); Couvelard, A (Couvelard, A.); Pezzella, F (Pezzella, F.); Dirix, LY (Dirix, L. Y.); Vermeulen, PB (Vermeulen, P. B.); Van Marck, EA (Van Marck, E. A.); Hasebe, T (Hasebe, T.) A fibrotic focus is a prognostic factor and a surrogate marker for hypoxia and (lymph)angiogenesis in breast cancer: review of the literature and proposal on the criteria of evaluation HISTOPATHOLOGY, 51 (4): 440-451 OCT 2007
    Sandlund, J (Sandlund, Johanna); Oosterwijk, E (Oosterwijk, Egbert); Grankvist, K (Grankvist, Kjell); Oosterwijk-Wakka, J (Oosterwijk-Wakka, Jeannette); Ljungberg, B (Ljungberg, Borje); Rasmuson, T (Rasmuson, Torgny) Prognostic impact of carbonic anhydrase IX expression in human renal cell carcinoma BJU INTERNATIONAL, 100 (3): 556-560 SEP 2007
    Lester, RD (Lester, Robin D.); Jo, M (Jo, Minji); Montel, V (Montel, Valerie); Takimoto, S (Takimoto, Shinako); Gonias, SL (Gonias, Steven L.) uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells JOURNAL OF CELL BIOLOGY, 178 (3): 425-436 JUL 30 2007
    Vaupel P, Mayer A Hypoxia in cancer: significance and impact on clinical outcome CANCER AND METASTASIS REVIEWS Volume: 26 Issue: 2 Pages: 225-239 2007
    Zelnak AB, O'Regan RM Targeting angiogenesis in advanced breast cancer BIODRUGS Volume: 21 Issue: 4 Pages: 209-214 Published: 2007
    Moon, EJ (Moon, Eui Jung); Brizel, DM (Brizel, David M.); Chi, JTA (Chi, Jen-Tsan Ashley); Dewhirst, MW (Dewhirst, Mark W.) The potential role of intrinsic hypoxia markers as prognostic variables in cancer ANTIOXIDANTS & REDOX SIGNALING, 9 (8): 1237-1294 AUG 2007
    Baldewijns, MM (Baldewijns, M. M.); Thijssen, VL (Thijssen, V. L.); Van den Eynden, GG (Van den Eynden, G. G.); Van Laere, SJ (Van Laere, S. J.); Bluekens, AM (Bluekens, A. M.); Roskams, T (Roskams, T.); van Poppel, H (van Poppel, H.); De Bruine, AP (De Bruine, A. P.); Griffioen, AW (Griffioen, A. W.); Vermeulen, PB (Vermeulen, P. B.) High-grade clear cell renal cell carcinoma has a higher angiogenic activity than low-grade renal cell carcinoma based on histomorphological quantification and qRT-PCR mRNA expression profile BRITISH JOURNAL OF CANCER, 96 (12): 1888-1895 JUN 18 2007
    Wilson GD Hypoxia and prognosis: the oxygen tension mounts FRONTIERS IN BIOSCIENCE Volume: 12 Pages: 3502-3518 Published: 2007
    Jacobsen FE, Lewis JA, Cohen SM The design of inhibitors for medicinally relevant metalloproteins CHEMMEDCHEM Volume: 2 Issue: 2 Pages: 152-171 Published: 2007
    Van den Eynden, GG (Van den Eynden, Gert G.); Van Laere, SJ (Van Laere, Steven J.); Van der Auwera, I (Van der Auwera, Ilse); Gilles, L (Gilles, Leen); Burn, JL (Burn, J. Lance); Colpaert, C (Colpaert, Cecile); van Dam, P (van Dam, Peter); Van Marck, EA (Van Marck, Eric A.); Dirix, LY (Dirix, Luc Y.); Vermeulen, PB (Vermeulen, Peter B.) CLINICAL & EXPERIMENTAL METASTASIS Volume: 24 Issue: 1 Pages: 13-23 Published: MAR 2007
    Korkolopoulou, P (Korkolopoulou, Penelope); Perdiki, M (Perdiki, Marina); Thymara, I (Thymara, Irini); Boviatsis, E (Boviatsis, Efstathios); Agrogiannis, G (Agrogiannis, George); Kotsiakis, X (Kotsiakis, Xenophon); Angelidakis, D (Angelidakis, Dimitrios); Rologis, D (Rologis, Dimitrios); Diamantopoulou, K (Diamantopoulou, Kalliopi); Thomas-Tsagli, E (Thomas-Tsagli, Euphemia); Kaklamanis, L (Kaklamanis, Loukas); Gatter, K (Gatter, Kevin); Patsouris, E (Patsouris, Efstratios) Expression of hypoxia-related tissue factors in astrocytic gliomas. A multivariate survival study with emphasis upon carbonic anhydrase IX HUMAN PATHOLOGY, 38 (4): 629-638 APR 2007
    Sansone, P (Sansone, Pasquale); Storci, G (Storci, Gianluca); Giovannini, C (Giovannini, Catia); Pandolfi, S (Pandolfi, Silvia); Pianetti, S (Pianetti, Simona); Taffurelli, M (Taffurelli, Mario); Santini, D (Santini, Donatella); Ceccarelli, C (Ceccarelli, Claudio); Chieco, P (Chieco, Pasquale); Bonafe, M (Bonafe, Massimiliano) p66Shc/Notch-3 interplay controls self-renewal and hypoxia survival in human stem/progenitor cells of the mammary gland expanded in vitro as mammospheres STEM CELLS, 25 (3): 807-815 MAR 2007
    Henning, EC (Henning, Erica C.); Azuma, C (Azuma, Chieko); Sotak, CH (Sotak, Christopher H.); Helmer, KG (Helmer, Karl G.) Multispectral quantification of tissue types in a RIF-1 tumor model with histological validation. Part I MAGNETIC RESONANCE IN MEDICINE, 57 (3): 501-512 MAR 2007
    Trastour, C (Trastour, Cynthia); Benizri, E (Benizri, Emmanuel); Ettore, F (Ettore, Francette); Ramaioli, A (Ramaioli, Alain); Chamorey, E (Chamorey, Emmanuel); Pouyssegur, J (Pouyssegur, Jacques); Berra, E (Berra, Edurne) HIF-1 alpha and CA IX staining in invasive breast carcinomas: Prognosis and treatment outcome INTERNATIONAL JOURNAL OF CANCER, 120 (7): 1451-1458 APR 1 2007
    Li, G (Li, G.); Passebosc-Faure, K (Passebosc-Faure, K.); Feng, G (Feng, G.); Lambert, C (Lambert, C.); Cottier, M (Cottier, M.); Gentil-Perret, A (Gentil-Perret, A.); Fournel, P (Fournel, P.); Perol, M (Perol, M.); Genin, C (Genin, C.) MN/CA9: a potential gene marker for detection of malignant cells in effusions BIOMARKERS, 12 (2): 214-220 MAR-APR 2007
    Westwell AD Novel antitumour agents: indanesulfonamides as selective inhibitors of the tumour-associated isozyme carbonic anhydrase IX DRUG DISCOVERY TODAY Volume: 12 Issue: 1-2 Pages: 100-100 Published: JAN 2007
    Yoo, H (Yoo, Heon); Baia, GS (Baia, Gilson S.); Smith, JS (Smith, Justin S.); McDermott, MW (McDermott, Michael W.); Bollen, AW (Bollen, Andrew W.); Berg, SRV (Berg, Scott R. Vanden); Lamborn, KR (Lamborn, Kathleen R.); Lal, A (Lal, Anita) Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas CLINICAL CANCER RESEARCH, 13 (1): 68-75 JAN 1 2007
    Laversin, S.A., Miles, A.K., Ball, G.R., Rees, R.C. Emerging breast cancer biomarkers Current Cancer Therapy Reviews 4 (2), pp. 79-85 , 2008
    Crabb, S.J., Bajdik, C.D., Leung, S., Speers, C.H., Kennecke, H., Huntsman, D.G., Gelmon, K.A. Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study Breast Cancer Research 10 (1), art. no. R6 , 2008
    Al-Ahmadie, H.A.a , Alden, D.a , Qin, L.-X.b , Olgac, S.a , Fine, S.W.a , Gopalan, A.a , Russo, P.c , Motzer, R.J.d , Reuter, V.E.a , Tickoo, S.K Carbonic anhydrase IX expression in clear cell renal cell carcinoma: An immunohistochemical study comparing 2 antibodies American Journal of Surgical Pathology 32 (3), pp. 377-382 , 2008
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    Wang YP (Wang, Yanping)1, Wang XY (Wang, Xiang-Yang)1,2, Subjeck JR (Subjeck, John R.)2, Kim HL (Kim, Hyung L.)1,2 Carbonic anhydrase IX has chaperone-like functions and is an immunoadjuvant MOLECULAR CANCER THERAPEUTICS Volume: 7 Issue: 12 Pages: 3867-3877 Published: DEC 2008
    Tanaka N (Tanaka, N.)1, Kato H (Kato, H.)1, Inose T (Inose, T.)1, Kimura H (Kimura, H.)1, Faried A (Faried, A.)1, Sohda M (Sohda, M.)1, Nakajima M (Nakajima, M.)1, Fukai Y (Fukai, Y.)1, Miyazaki T (Miyazaki, T.)1, Masuda N (Masuda, N.)1, Fukuchi M (Fukuchi, M.)1, Kuwano H (Kuwano, H.)1 Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma BRITISH JOURNAL OF CANCER Volume: 99 Issue: 9 Pages: 1468-1475 Published: OCT 28 2008
    Rasheed S (Rasheed, Shahnawaz)1, McDonald PJ (McDonald, Peter J.)1, Northover JM (Northover, John M.)1, Guenther T (Guenther, Thomas)2 Angiogenesis and hypoxic factors in colorectal cancer PATHOLOGY RESEARCH AND PRACTICE Volume: 204 Issue: 7 Pages: 501-510 Published: 2008
    Yasuda H Solid tumor physiology and hypoxia-induced chemo/radio-resistance: Novel strategy for cancer therapy: Nitric oxide donor as a therapeutic enhancer NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 19 Issue: 2 Pages: 205-216 Published: SEP 2008
    Jen YF (Jen, Yi-Fan)1, Lee WM (Lee, Wei-Ming)2, Lin CC (Lin, Cheng-Chung)2, Cheng YH (Cheng, Yeong-Hsiang)3, Wang JH (Wang, Jiann-Hsiung)1, Kuo TF (Kuo, Tzong-Fu)4, Chang MH (Chang, Ming-Huang)1 The expression of carbonic anhydrase in canine mammary gland and mammary gland tumor JOURNAL OF VETERINARY MEDICAL SCIENCE Volume: 70 Issue: 5 Pages: 437-441 Published: MAY 2008
    Kyndi M (Kyndi, Marianne)1,2, Sorensen FB (Sorensen, Flemming B.)2, Knudsen H (Knudsen, Helle)3, Alsner J (Alsner, Jan)1, Overgaard M (Overgaard, Marie)4, Nielsen HM (Nielsen, Hanne M.)1, Overgaard J (Overgaard, Jens)1 Carbonic anhydrase IX and response to postmastectomy radiotherapy in high-risk breast cancer: a subgroup analysis of the DBCG82 b and c trials BREAST CANCER RESEARCH Volume: 10 Issue: 2 Article Number: R24 Published: 2008
    Saczewski F (Saczewski, Franciszek)1, Innocenti A (Innocenti, Alessio)2, Slawinski J (Slawinski, Jaroslaw)1, Kornicka A (Kornicka, Anita)1, Brzozowski Z (Brzozowski, Zdzislaw)1, Pomarnacka E (Pomarnacka, Elzbieta)1, Scozzafava A (Scozzafava, Andrea)2, Temperini C (Temperini, Claudia)2, Supuran CT (Supuran, Claudiu T.)2 Carbonic anhydrase inhibitors: Inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides BIOORGANIC & MEDICINAL CHEMISTRY Volume: 16 Issue: 7 Pages: 3933-3940 Published: APR 1 2008
    Parkkila S Significance of pH regulation and carbonic anhydrases in tumour progression and implications for diagnostic and therapeutic approaches Conference Information: International Carbonic Anhydrase IX (CAIX) Symposium, NOV, 2007 Brussels, BELGIUM BJU INTERNATIONAL Volume: 101 Pages: 16-21 Supplement: Suppl. 4 Published: JUN 2008
    Shuch B (Shuch, Brian)1, Li ZH (Li, Zhenhua)1, Belldegrun AS (Belldegrun, Arie S.)1 Carbonic anhydrase IX and renal cell carcinoma: prognosis, response to systemic therapy, and future vaccine strategies BJU INTERNATIONAL Volume: 101 Pages: 25-30 Supplement: Suppl. 4 Published: JUN 2008
    Gunawan R (Gunawan, R.)1, Tenti G (Tenti, G.)1, Sivaloganathan S (Sivaloganathan, S.) Bayesian Inference of Tumor Hypoxia 29th International Workshop on Bayesian Inference and Maximum Entropy Methods in Science and Engineering Oxford, MS, JUL 05-10, 2009, BAYESIAN INFERENCE AND MAXIMUM ENTROPY METHODS IN SCIENCE AND ENGINEERING Book Series: AIP Conference Proceedings Volume: 1193 Pages: 336-343 Published: 2009
    Liao SY (Liao, Shu-Yuan)1, Rodgers WH (Rodgers, William H.)2, Kauderer J (Kauderer, James)3, Bonfiglio TA (Bonfiglio, Thomas A.)4, Walker JL (Walker, Joan L.)5, Darcy KM (Darcy, Kathleen M.)3, Carter R (Carter, Randy)3, Hatae M (Hatae, Masayuji)6, Levine L (Levine, Lyuba)7, Spirtos NM (Spirtos, Nick M.)8,9, Stanbridge EJ (Stanbridge, Eric J.)10 Carbonic anhydrase IX and human papillomavirus as diagnostic biomarkers of cervical dysplasia/neoplasia in women with a cytologic diagnosis of atypical glandular cells: A Gynecologic Oncology Group study in United States INTERNATIONAL JOURNAL OF CANCER Volume: 125 Issue: 10 Pages: 2434-2440 Published: NOV 15 2009
    Li Y (Li, Ying)1, Wang H (Wang, Hai)1, Oosterwijk E (Oosterwijk, Egbert)3, Selman Y (Selman, Yamil)2, Mira JC (Mira, Juan C.)2, Medrano T (Medrano, Theresa)2, Shiverick KT (Shiverick, Kathleen T.)2, Frost SC (Frost, Susan C.)1 Antibody-specific detection of CAIX in breast and prostate cancers BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Volume: 386 Issue: 3 Pages: 488-492 Published: AUG 28 2009
    Nakao M (Nakao, Masayuki)1,2, Ishii G (Ishii, Genichiro)1, Nagai K (Nagai, Kanji)2, Kawase A (Kawase, Akikazu)1,2, Kenmotsu H (Kenmotsu, Hirotsugu)1,2, Kon-No H (Kon-no, Hidehiro)1,2, Hishica T (Hishica, Tomoyuki)2, Nishimura M (Nishimura, Mitsuyo)2, Yoshida J (Yoshida, Junji)2, Ochiai A (Ochiai, Atsushi)1 Prognostic Significance of Carbonic Anhydrase IX Expression by Cancer-associated Fibroblasts in Lung Adenocarcinoma CANCER Volume: 115 Issue: 12 Pages: 2732-2743 Published: JUN 15 2009
    Kaluz S (Kaluz, Stefan)1, Kaluzova M (Kaluzova, Milota)1, Liao SY (Liao, Shu-Yuan)2, Lerman M (Lerman, Michael)3, Stanbridge EJ (Stanbridge, Eric J.)1 Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show? BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER Volume: 1795 Issue: 2 Pages: 162-172 Published: APR 2009
    Ranalli NJ (Ranalli, Nathan J.)1, Evans SM (Evans, Sydney M.)2, Ju KD (Ju, Kevin D.)1 Hypoxia in Brain Tumors A Review of the Literature NEUROSURGERY QUARTERLY Volume: 19 Issue: 1 Pages: 1-12 Published: MAR 2009
    Korkeila E (Korkeila, E.)1, Talvinen K (Talvinen, K.)2, Jaakkola PM (Jaakkola, P. M.)1,3,4, Minn H (Minn, H.)1,5, Syrjanen K (Syrjanen, K.)1, Sundstrom J (Sundstrom, J.)2,6, Pyrhonen S (Pyrhonen, S.)1 Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer BRITISH JOURNAL OF CANCER Volume: 100 Issue: 6 Pages: 874-880 Published: MAR 17 2009
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    Dachs GU (Dachs, Gabi U.)1, Kano M (Kano, Maiko)1, Volkova E (Volkova, Ekaterina)1, Morrin HR (Morrin, Helen R.)1,2, Davey VCL (Davey, Valerie C. L.)3, Harris GC (Harris, Gavin C.)3, Cheale M (Cheale, Michelle)3, Frampton C (Frampton, Christopher)4, Currie MJ (Currie, Margaret J.)1, Wells JE (Wells, J. Elisabeth), Robinson BA (Robinson, Bridget A.) A profile of prognostic and molecular factors in European and Maori breast cancer patients BMC CANCER Volume: 10 Article Number: 543 Published: OCT 10 2010
    Rundqvist H, Johnson RS Hypoxia and Metastasis in Breast Cancer DIVERSE EFFECTS OF HYPOXIA ON TUMOR PROGRESSION Book Series: Current Topics in Microbiology and Immunology Volume: 345 Pages: 121-139 Published: 2010
    Hiraoka N (Hiraoka, N.)1, Ino Y (Ino, Y.)1, Sekine S (Sekine, S.)1, Tsuda H (Tsuda, H.)2, Shimada K (Shimada, K.)3, Kosuge T (Kosuge, T.)3, Zavada J (Zavada, J.)4, Yoshida M (Yoshida, M.)2, Yamada K (Yamada, K.)2, Koyama T (Koyama, T.)2, Kanai Y (Kanai, Y.) Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation BRITISH JOURNAL OF CANCER Volume: 103 Issue: 7 Pages: 1057-1065 Published: SEP 28 2010
    Prayson RA (Prayson, Richard A.), Chamberlain WA (Chamberlain, Wendy A.), Angelov L (Angelov, Lilyana) Clear Cell Meningioma: A Clinicopathologic Study of 18 Tumors and Examination of the Use of CD10, CA9, and RCC Antibodies to Distinguish Between Clear Cell Meningioma and Metastatic Clear Cell Renal Cell Carcinoma APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY Volume: 18 Issue: 5 Pages: 422-428 Published: OCT 2010
    Papworth K (Papworth, Karin)1, Sandlund J (Sandlund, Johanna)2, Grankvist K (Grankvist, Kjell)3, Ljungberg B (Ljungberg, Borje)4, Rasmuson T (Rasmuson, Torgny) Soluble Carbonic Anhydrase IX Is Not an Independent Prognostic Factor in Human Renal Cell Carcinoma ANTICANCER RESEARCH Volume: 30 Issue: 7 Pages: 2953-2957 Published: JUL 2010
    Chiche J (Chiche, Johanna)1, Ilc K (Ilc, Karine)1, Brahimi-Horn MC (Brahimi-Horn, M. Christiane)1, Pouyssegur J (Pouyssegur, Jacques) Membrane-bound carbonic anhydrases are key pH regulators controlling tumor growth and cell migration 50th International Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic Tissues Univ Bologna, Bologna, ITALY, SEP 27-29, 2009 , ADVANCES IN ENZYME REGULATION, VOL 50 Book Series: Advances in Enzyme Regulation Volume: 50 Pages: 20-33 Published: 2010
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    Carlin S (Carlin, Sean)1,2, Khan N (Khan, Nahida)1, Ku T (Ku, Thomas)1, Longo VA (Longo, Valerie A.)1, Larson SM (Larson, Steve M.)1, Smith-Jones PM (Smith-Jones, Peter M.) Molecular Targeting of Carbonic Anhydrase IX in Mice with Hypoxic HT29 Colorectal Tumor Xenografts PLOS ONE Volume: 5 Issue: 5 Article Number: e10857 Published: MAY 27 2010
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    Chiche J, Brahimi-Horn MC, Pouyssegur J Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Volume: 14 Issue: 4 Pages: 771-794 Published: APR 2010
    Wang Y, Ohh M Oxygen-mediated endocytosis in cancer JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Volume: 14 Issue: 3 Pages: 496-503 Published: MAR 2010
    Ansari J (Ansari, J.)1, Glaholm J (Glaholm, J.)2, McMenemin R (McMenemin, R.)3, James ND (James, N. D.)2, Hussain SA (Hussain, S. A Recent Advances and Future Directions in the Management of Metastatic Renal Cell Carcinoma ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY Volume: 10 Issue: 3 Pages: 225-235 Published: MAR 2010
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    Touisni, N (Touisni, Nadia)1; Maresca, A (Maresca, Alfonso)2; McDonald, PC (McDonald, Paul C.)3,4; Lou, YM (Lou, Yuanmei)3,4; Scozzafava, A (Scozzafava, Andrea)2; Dedhar, S (Dedhar, Shoukat)3,4,5; Winum, JY (Winum, Jean-Yves)1; Supuran, CT (Supuran, Claudiu T.)2 Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors JOURNAL OF MEDICINAL CHEMISTRY Volume: 54 Issue: 24 Pages: 8271-8277 DOI: 10.1021/jm200983e Published: DEC 22 2011
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    Wennemers, M (Wennemers, Marloes)1,2; Bussink, J (Bussink, Johan)2; Scheijen, B (Scheijen, Blanca)3; Nagtegaal, ID (Nagtegaal, Iris D.)4; van Laarhoven, HWM (van Laarhoven, Hanneke W. M.)5; Raleigh, JA (Raleigh, James A.)6; Varia, MA (Varia, Mahesh A.)6; Heuvel, JJTM (Heuvel, Joop J. T. M.)1; Rouschop, KM (Rouschop, Kasper M.)7; Sweep, FCGJ (Sweep, Fred C. G. J.)1; Span, PN (Span, Paul N.)1,2 Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response BREAST CANCER RESEARCH Volume: 13 Issue: 4 Article Number: R82 DOI: 10.1186/bcr2934 Published: 2011
    Bao, B (Bao, Bin); Azmi, AS (Azmi, Asfar S.); Ali, S (Ali, Shadan); Ahmad, A (Ahmad, Aamir); Li, YW (Li, Yiwei); Banerjee, S (Banerjee, Sanjeev); Kong, DJ (Kong, Dejuan); Sarkar, FH (Sarkar, Fazlul H.)[ 1,2 ] The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER Volume: 1826 Issue: 2 Pages: 272-296 DOI: 10.1016/j.bbcan.2012.04.008 Published: DEC 2012
    Choi, J., Jung, W.-H., Koo, J.S. Metabolism-related proteins are differentially expressed according to the molecular subtype of invasive breast cancer defined by surrogate immunohistochemistry Pathobiology 80 (1) , pp. 41-52 , 2012
    Rausch, V.ab, Liu, L.ab, Apel, A.abf, Rettig, T.ab, Gladkich, J.ab, Labsch, S.ab, Kallifatidis, G.abg, Kaczorowski, A.ab, Groth, A.abh, Gross, W.bc, Gebhard, M.M.bc, Schemmer, P.b, Werner, J.b, Salnikov, A.V.ad, Zentgraf, H.e, Büchler, M.W.b, Herr, I.ab Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment Journal of Pathology Volume 227, Issue 3, July 2012, Pages 325-335
    Bao, BN (Bao, Bagna)[ 1 ] ; Groves, K (Groves, Kevin)[ 1 ] ; Zhang, J (Zhang, Jun)[ 1 ] ; Handy, E (Handy, Emma)[ 1 ] ; Kennedy, P (Kennedy, Paul)[ 1 ] ; Cuneo, G (Cuneo, Garry)[ 1 ] ; Supuran, CT (Supuran, Claudiu T.)[ 2 ] ; Yared, W (Yared, Wael)[ 1 ] ; Rajopadhye, M (Rajopadhye, Milind)[ 1 ] ; Peterson, JD (Peterson, Jeffrey D.)[ 1 ] In Vivo Imaging and Quantification of Carbonic Anhydrase IX Expression as an Endogenous Biomarker of Tumor Hypoxia PLOS ONE Volume: 7 Issue: 11 Article Number: e50860 DOI: 10.1371/journal.pone.0050860 Published: NOV 30 2012
    Kornegoor, R (Kornegoor, Robert)[ 1 ] ; Verschuur-Maes, AHJ (Verschuur-Maes, Anoek H. J.)[ 1 ] ; Buerger, H (Buerger, Horst)[ 2 ] ; Hogenes, MCH (Hogenes, Marieke C. H.)[ 3 ] ; de Bruin, PC (de Bruin, Peter C.)[ 4 ] ; Oudejans, JJ (Oudejans, Joost J.)[ 5 ] ; Hinrichs, B (Hinrichs, Bernd)[ 6 ] ; van Diest, PJ (van Diest, Paul J.)[ 1 ] Fibrotic focus and hypoxia in male breast cancer MODERN PATHOLOGY Volume: 25 Issue: 10 Pages: 1397-1404 DOI: 10.1038/modpathol.2012.101 Published: OCT 2012
    Salnikov, AV (Salnikov, Alexei V.)[ 1,2,3 ] ; Liu, L (Liu, Li)[ 1 ] ; Platen, M (Platen, Mitja)[ 1 ] ; Gladkich, J (Gladkich, Jury)[ 1 ] ; Salnikova, O (Salnikova, Olga); Ryschich, E (Ryschich, Eduard); Mattern, J (Mattern, Juergen); Moldenhauer, G (Moldenhauer, Gerhard)[ 2,3 ] ; Werner, J (Werner, Jens); Schemmer, P (Schemmer, Peter); Buchler, MW (Buechler, Markus W.); Herr, I (Herr, Ingrid)[ 1 ] Hypoxia Induces EMT in Low and Highly Aggressive Pancreatic Tumor Cells but Only Cells with Cancer Stem Cell Characteristics Acquire Pronounced Migratory Potential PLOS ONE Volume: 7 Issue: 9 Article Number: e46391 DOI: 10.1371/journal.pone.0046391 Published: SEP 26 2012
    Lee-Kong, SA (Lee-Kong, Steven A.); Ruby, JA (Ruby, Jeannine A.); Chessin, DB (Chessin, David B.); Pucciarelli, S (Pucciarelli, Salvatore)[ 2 ] ; Shia, JR (Shia, Jinru)[ 3 ] ; Riedel, ER (Riedel, Elyn R.)[ 4 ] ; Nitti, D (Nitti, Donato)[ 2 ] ; Guillem, JG (Guillem, Jose G.)[ 1 ] Hypoxia-Related Proteins in Patients With Rectal Cancer Undergoing Neoadjuvant Combined Modality Therapy DISEASES OF THE COLON & RECTUM Volume: 55 Issue: 9 Pages: 990-995 DOI: 10.1097/DCR.0b013e31825bd80c Published: SEP 2012
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    Winum, JY (Winum, Jean-Yves)[ 2 ] ; Carta, F (Carta, Fabrizio)[ 1 ] ; Ward, C (Ward, Carol)[ 3,4 ] ; Mullen, P (Mullen, Peter)[ 3,4 ] ; Harrison, D (Harrison, David)[ 5 ] ; Langdon, SP (Langdon, Simon P.)[ 3,4 ] ; Cecchi, A (Cecchi, Alessandro)[ 1 ] ; Scozzafava, A (Scozzafava, Andrea)[ 1 ] ; Kunkler, I (Kunkler, Ian)[ 6 ] ; Supuran, CT (Supuran, Claudiu T.)[ 1,7 ] Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Volume: 22 Issue: 14 Pages: 4681-4685 DOI: 10.1016/j.bmcl.2012.05.083 Published: JUL 15 2012
    de Putte, MV (de Putte, Marie Van)[ 1 ] ; Marysael, T (Marysael, Thierry)[ 1 ] ; Fonge, H (Fonge, Humphrey)[ 2 ] ; Roskams, T (Roskams, Tania)[ 3 ] ; Cona, MM (Cona, Marlein Miranda)[ 4 ] ; Li, JJ (Li, Junjie)[ 4 ] ; Bormans, G (Bormans, Guy)[ 2 ] ; Verbruggen, A (Verbruggen, Alfons)[ 2 ] ; Ni, YC (Ni, Yicheng)[ 4 ] ; de Witte, PAM (de Witte, Peter A. M.)[ 1 ] Radiolabeled iodohypericin as tumor necrosis avid tracer: diagnostic and therapeutic potential INTERNATIONAL JOURNAL OF CANCER Volume: 131 Issue: 2 Pages: E129-E137 DOI: 10.1002/ijc.26492 Published: JUL 15 2012
    Singh, Shalini A QSAR Study on Novel Series of Carbonic Anhydrase Inhibitors hCA IX-Tumor-Associated (Hypoxia) MEDICINAL CHEMISTRY Volume: 8 Issue: 4 Pages: 656-672 Published: JUL 2012
    Gieling, RG (Gieling, Roben G.)[ 2 ] ; Babur, M (Babur, Muhammad)[ 2 ] ; Mamnani, L (Mamnani, Lupti)[ 2 ] ; Burrows, N (Burrows, Natalie)[ 2 ] ; Telfer, BA (Telfer, Brian A.)[ 2 ] ; Carta, F (Carta, Fabrizio)[ 1 ] ; Winum, JY (Winum, Jean-Yves)[ 3 ] ; Scozzafava, A (Scozzafava, Andrea)[ 1 ] ; Supuran, CT (Supuran, Claudiu T.)[ 1 ] ; Williams, KJ (Williams, Kaye J.)[ 2 ] Antimetastatic Effect of Sulfamate Carbonic Anhydrase IX Inhibitors in Breast Carcinoma Xenografts JOURNAL OF MEDICINAL CHEMISTRY Volume: 55 Issue: 11 Pages: 5591-5600 DOI: 10.1021/jm300529u Published: JUN 14 2012
    Singh, Shalini In Silico Modeling of Carbonic Anhydrase Inhibitor hCA IX-Tumor Associated (Hypoxia) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES Volume: 82 Issue: 2 Pages: 113-123 DOI: 10.1007/s40010-012-0018-8 Published: JUN 2012
    Yan, W (Yan, Wei)[ 1 ] ; Chang, Y (Chang, Ying)[ 1 ] ; Liang, XY (Liang, Xiaoyan)[ 1 ] ; Cardinal, JS (Cardinal, Jon S.)[ 1 ] ; Huang, H (Huang, Hai)[ 1 ] ; Thorne, SH (Thorne, Stephen H.)[ 2 ] ; Monga, SPS (Monga, Satdarshan P. S.)[ 3 ] ; Geller, DA (Geller, David A.)[ 1 ] ; Lotze, MT (Lotze, Michael T.)[ 1 ] ; Tsung, A (Tsung, Allan)[ 1 ] High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases HEPATOLOGY Volume: 55 Issue: 6 Pages: 1863-1875 DOI: 10.1002/hep.25572 Published: JUN 2012
    Tu, CK (Tu, Chingkuang)[ 2 ] ; Foster, L (Foster, Lauren)[ 1 ] ; Alvarado, A (Alvarado, Andrea)[ 1 ] ; McKenna, R (McKenna, Robert)[ 1 ] ; Silverman, DN (Silverman, David N.)[ 2 ] ; Frost, SC (Frost, Susan C.)[ 1 ] Role of zinc in catalytic activity of carbonic anhydrase IX ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS Volume: 521 Issue: 1-2 Pages: 90-94 DOI: 10.1016/j.abb.2012.03.017 Published: MAY 2012
    Betof, AS (Betof, A. S.)[ 1 ] ; Rabbani, ZN (Rabbani, Z. N.)[ 2 ] ; Hardee, ME (Hardee, M. E.)[ 1 ] ; Kim, SJ (Kim, S. J.)[ 3 ] ; Broadwater, G (Broadwater, G.)[ 4 ] ; Bentley, RC (Bentley, R. C.)[ 1 ] ; Snyder, SA (Snyder, S. A.)[ 2 ] ; Vujaskovic, Z (Vujaskovic, Z.)[ 2 ] ; Oosterwijk, E (Oosterwijk, E.)[ 5 ] ; Harris, LN (Harris, L. N.)[ 6 ] ; Horton, JK (Horton, J. K.)[ 2 ] ; Dewhirst, MW (Dewhirst, M. W.)[ 1,2 ] ; Blackwell, KL (Blackwell, K. L.)[ 2,7 ] Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification BRITISH JOURNAL OF CANCER Volume: 106 Issue: 5 Pages: 916-922 DOI: 10.1038/bjc.2012.32 Published: FEB 28 2012
    Carta, F (Carta, Fabrizio)[ 1 ] ; Aggarwal, M (Aggarwal, Mayank)[ 2 ] ; Maresca, A (Maresca, Alfonso)[ 1 ] ; Scozzafava, A (Scozzafava, Andrea)[ 1 ] ; McKenna, R (McKenna, Robert)[ 2 ] ; Masin, E (Masin, Emanuela)[ 3 ] ; Supuran, CT (Supuran, Claudiu T.)[ 1 ] Dithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in Vivo JOURNAL OF MEDICINAL CHEMISTRY Volume: 55 Issue: 4 Pages: 1721-1730 DOI: 10.1021/jm300031j Published: FEB 23 2012
    Petrul, HM (Petrul, Heike M.)[ 1 ] ; Schatz, CA (Schatz, Christoph A.)[ 1 ] ; Kopitz, CC (Kopitz, Charlotte C.)[ 1 ] ; Adnane, L (Adnane, Lila)[ 1 ] ; McCabe, TJ (McCabe, Timothy J.)[ 1 ] ; Trail, P (Trail, Pamela)[ 1 ] ; Ha, S (Ha, Sha)[ 1 ] ; Chang, YS (Chang, Yong S.)[ 1 ] ; Voznesensky, A (Voznesensky, Andrei)[ 1 ] ; Ranges, G (Ranges, Gerald)[ 1 ] ; Tamburini, PP (Tamburini, Paul P.)[ 1 ] Therapeutic Mechanism and Efficacy of the Antibody-Drug Conjugate BAY 79-4620 Targeting Human Carbonic Anhydrase 9 MOLECULAR CANCER THERAPEUTICS Volume: 11 Issue: 2 Pages: 340-349 DOI: 10.1158/1535-7163.MCT-11-0523 Published: FEB 2012
    McDonald, PC (McDonald, Paul C.)[ 1,2 ] ; Winum, JY (Winum, Jean-Yves)[ 3 ] ; Supuran, CT (Supuran, Claudiu T.)[ 4 ] ; Dedhar, S (Dedhar, Shoukat)[ 1,2,5 ] Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics ONCOTARGET Volume: 3 Issue: 1 Pages: 84-97 Published: JAN 2012
    Groves, K (Groves, Kevin)[ 1 ] ; Bao, B (Bao, Bagna)[ 1 ] ; Zhang, J (Zhang, Jun)[ 1 ] ; Handy, E (Handy, Emma)[ 1 ] ; Kennedy, P (Kennedy, Paul)[ 1 ] ; Cuneo, G (Cuneo, Garry)[ 1 ] ; Supuran, CT (Supuran, Claudiu T.)[ 2 ] ; Yared, W (Yared, Wael)[ 1 ] ; Peterson, JD (Peterson, Jeffrey D.)[ 1 ] ; Rajopadhye, M (Rajopadhye, Milind)[ 1 ] Synthesis and evaluation of near-infrared fluorescent sulfonamide derivatives for imaging of hypoxia-induced carbonic anhydrase IX expression in tumors BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Volume: 22 Issue: 1 Pages: 653-657 DOI: 10.1016/j.bmcl.2011.10.058 Published: JAN 1 2012
    Kim, BR (Kim, B. -R.)[ 1,2 ] ; Yang, EK (Yang, E. -K.)[ 2 ] ; Kim, DY (Kim, D. -Y.)[ 3 ] ; Kim, SH (Kim, S. -H.)[ 2 ] ; Moon, DC (Moon, D. -C.)[ 1 ] ; Lee, JH (Lee, J. -H.)[ 1 ] ; Kim, HJ (Kim, H. -J.)[ 4 ] ; Lee, JC (Lee, J. -C.)[ 1 ] Generation of anti-tumour immune response using dendritic cells pulsed with carbonic anhydrase IX-Acinetobacter baumannii outer membrane protein A fusion proteins against renal cell carcinoma CLINICAL AND EXPERIMENTAL IMMUNOLOGY Volume: 167 Issue: 1 Pages: 73-83 DOI: 10.1111/j.1365-2249.2011.04489.x Published: JAN 2012
    Tafreshi, NK (Tafreshi, Narges K.)[ 1 ] ; Bui, MM (Bui, Marilyn M.)[ 2,3,5 ] ; Bishop, K (Bishop, Kellsey)[ 1 ] ; Lloyd, MC (Lloyd, Mark C.)[ 3 ] ; Enkemann, SA (Enkemann, Steven A.)[ 4 ] ; Lopez, AS (Lopez, Alexis S.)[ 2 ] ; Abrahams, D (Abrahams, Dominique)[ 6 ] ; Carter, BW (Carter, Bradford W.)[ 5 ] ; Vagner, J (Vagner, Josef)[ 7 ] ; Gobmyer, SR (Gobmyer, Stephen R.)[ 8 ] ; Gillies, RJ (Gillies, Robert J.)[ 1 ] ; Morse, DL (Morse, David L.)[ 1 ] Noninvasive Detection of Breast Cancer Lymph Node Metastasis Using Carbonic Anhydrases IX and XII Targeted Imaging Probes CLINICAL CANCER RESEARCH Volume: 18 Issue: 1 Pages: 207-219 DOI: 10.1158/1078-0432.CCR-11-0238 Published: JAN 1 2012
    Sahebjamee, H.a , Yaghmaei, P.a, Abdolmaleki, P.b, Foroumadi, A.R. Quantitative structure - Activity relationships study of carbonic anhydrase inhibitors using Logistic Regression model Iranian Journal of Chemistry and Chemical Engineering Volume 32, Issue 2, 2013, Pages 19-29
    Adams, A.a , van Brussel, A.S.A.b , Vermeulen, J.F.b , Mali, W.P.a , van der Wall, E.c , van Diest, P.J.b , Elias, S.G. The potential of hypoxia markers as target for breast molecular imaging - a systematic review and meta-analysis of human marker expression BMC Cancer Volume 13, 10 November 2013, Article number 538
    Won, J.R.ab, Gao, D.b, Chow, C.b, Cheng, J.b, Lau, S.Y.b, Ellis, M.J.c, Perou, C.M.d, Bernard, P.S.e, Nielsen, T.O. A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard Modern Pathology Volume 26, Issue 11, November 2013, Pages 1438-1450
    Shareef, M.M.ab , Udayakumar, T.S.ab, Sinha, V.K.abc, Saleem, S.M.d, Griggs, W.W. Interaction of HIF-1α and Notch3 Is Required for the Expression of Carbonic Anhydrase 9 in Breast Carcinoma Cells Genes and Cancer Volume 4, Issue 11-12, November 2013, Pages 513-523
    Kajo, K.a , Turčan, I.b, Vallová, M.a, Laboš, T.a, Kajo, M.a, Macháleková, K.a, Galbavý, Š.ac, Žúbor, P. Expression of carbonic anhydrase IX in the breast Carcinomas [Expresia karbonickej anhydrázy IX v karcinómoch prsníka] Ceska Gynekologie Volume 78, Issue 3, 2013, Pages 263-268
    Rundqvist, H.a , Johnson, R.S. Tumour oxygenation: Implications for breast cancer prognosis Journal of Internal Medicine Volume 274, Issue 2, August 2013, Pages 105-112
    Fiaschi, T.a, Giannoni, E.a, Taddei, M.L.a, Cirri, P.a, Marini, A.b, Pintus, G.b, Nativi, C.c, Richichi, B.c, Scozzafava, A.c, Carta, F.d, Torre, E.a, Supuran, C.T.d, Chiarugi, P. Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells Cell Cycle Volume 12, Issue 11, 1 June 2013, Pages 1791-1801
    Kim, S., Jung, W.H., Koo, J.S. The expression of Glut-1, CAIX, and MCT4 in Mucinous carcinoma Journal of Breast Cancer Volume 16, Issue 2, June 2013, Pages 146-151
    Schütze, D.a, Milde-Langosch, K.a, Witzel, I.a, Rody, A.b, Karn, T.c, Schmidt, M.d, Choschzick, M.e, Jänicke, F.a, Müller, V. Relevance of cellular and serum carbonic anhydrase IX in primary breast cancer ournal of Cancer Research and Clinical Oncology Volume 139, Issue 5, May 2013, Pages 747-754
    Xue, T.a, Zhang, Y.a, Zhang, L.b, Yao, L.a, Hu, X.a , Xu, L.X. Proteomic analysis of two metabolic proteins with potential to translocate to plasma membrane associated with tumor metastasis development and drug targets Journal of Proteome Research Volume 12, Issue 4, 5 April 2013, Pages 1754-1763
    Gieling, R.G. , Williams, K.J. Carbonic anhydrase IX as a target for metastatic disease Bioorganic and Medicinal Chemistry Volume 21, Issue 6, 15 March 2013, Pages 1470-1476
    Mikami, Y.a , Minamiguchi, S.a, Teramoto, N.b, Nagura, M.c, Haga, H.a, Konishi, I. Carbonic anhydrase type IX expression in lobular endocervical glandular hyperplasia and gastric-type adenocarcinoma of the uterine cervix Pathology Research and Practice Volume 209, Issue 3, March 2013, Pages 173-178
    Kwon, J.E.a, Jung, W.-H.b, Koo, J.S. The expression of metabolism-related proteins in phyllodes tumors Tumor Biology Volume 34, Issue 1, February 2013, Pages 115-124
    Lu, G., Hillier, S.M., Maresca, K.P., Zimmerman, C.N., Eckelman, W.C., Joyal, J.L., Babich, J.W. Synthesis and SAR of novel Re/99mTc-Labeled benzenesulfonamide carbonic anhydrase IX inhibitors for molecular imaging of tumor hypoxia Journal of Medicinal Chemistry Volume 56, Issue 2, 24 January 2013, Pages 510-520
    Nagelkerke, A.ab , Bussink, J.a , Mujcic, H.cd , Wouters, B.G.cd , Lehmann, S.e , Sweep, F.C.G.J.b , Span, P.N. Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response Breast Cancer Research Volume 15, Issue 1, 7 January 2013, Article number R2
    Ostheimer, C., Vordermark, D. Osteopontin - an indicator of tumor hypoxia and treatment resistance (Chapter ) Hypoxia: Causes, Types and Management January 2013, Pages 255-318
    Shan, X.ab, Wang, D.a , Chen, J.b, Xiao, X.b, Jiang, Y.a, Wang, Y.b, Fan, Y. Necrosis degree displayed in computed tomography images correlated with hypoxia and angiogenesis in breast cancer Journal of Computer Assisted Tomography Volume 37, Issue 1, January 2013, Pages 22-28
    Choi, Junjeong; Jung, Woo-Hee; Koo, Ja Seung Metabolism-Related Proteins Are Differentially Expressed according to the Molecular Subtype of Invasive Breast Cancer Defined by Surrogate Immunohistochemistry PATHOBIOLOGY Volume: 80 Issue: 1 Pages: 41-52 Published: 2013
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    Fais, S (Fais, Stefano)[ 3,1 ] ; Venturi, G (Venturi, Giulietta)[ 1 ] ; Gatenby, B Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy CANCER AND METASTASIS REVIEWS Volume: 33 Issue: 4 Pages: 1095-1108 Special Issue: SI, 2014
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    Walsh, JC (Walsh, Joseph C.)[ 1 ] ; Lebedev, A (Lebedev, Artem)[ 1 ] ; Aten, E (Aten, Edward)[ 2 ] ; Madsen, K (Madsen, Kathleen)[ 3 ] ; Marciano, L (Marciano, Liane)[ 2 ] ; Kolb, HC The Clinical Importance of Assessing Tumor Hypoxia: Relationship of Tumor Hypoxia to Prognosis and Therapeutic Opportunities ANTIOXIDANTS & REDOX SIGNALING Volume: 21 Issue: 10 Pages: 1516-1554, 2014
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    Aly, R.a , Elghannam, D.M.a, Yousef, A.B. Relationships between TIMP-1, CAIX, and clinical outcomes in Egyptian breast cancer Comparative Clinical Pathology Volume 23, Issue 4, July 2014, Pages 907-916
    Rêgo, M.J.B.M.abc , Filho, A.F.S.ab, Cordeiro, M.F.ab, Santos, P.B.a, Beltrão, E.I.C. The glycomic profile of invasive ductal carcinoma of the breast is altered in patients with hypoxic regions: Implications for tumor behavior Folia Histochemica et Cytobiologica olume 52, Issue 2, 2014, Pages 96-103
    Kunkler, IH (Kunkler, Ian H.)[ 1 ] ; Ward, C (Ward, Carol)[ 2 ] ; Langdon, SP Technical innovation in adjuvant radiotherapy: Evolution and evaluation of new treatments for today and tomorrow BREAST Volume: 24 Pages: S114-S119 Supplement: 2, 2015
    Fakhrejahani, E (Fakhrejahani, Elham)[ 1 ] ; Toii, M (Toii, Masae)[ 1 ] ; Kitai, T (Kitai, Toshiyuki)[ 2 ] ; Kanao, S (Kanao, Shotaro)[ 3 ] ; Asao, Y (Asao, Yasufumi)[ 1,4 ] ; Hashizume, Y (Hashizume, Yohei)[ 4 ] ; Mikami, Y (Mikami, Yoshiki)[ 5 ] ; Yamaga, I (Yamaga, Iku)[ 1 ] ; Kataoka, M (Kataoka, Masako)[ 3 ] ; Sugie, T (Sugie, Tomoharu)[ 6 ] ; Takada, M (Takada, Masahiro)[ 1 ] ; Haga, H (Haga, Hironori)[ 7 ] ; Togashi, K (Togashi, Kaori)[ 3 ] ; Shiina, T (Shiina, Tsuyoshi)[ 8 ] ; Toi, M Clinical Report on the First Prototype of a Photoacoustic Tomography System with Dual Illumination for Breast Cancer Imaging PLOS ONE Volume: 10 Issue: 10 Article Number: e0139113, 2015
    Hu, W (Hu, Wei) High Accuracy Gene Signature for Chemosensitivity Prediction in Breast Cancer TSINGHUA SCIENCE AND TECHNOLOGY Volume: 20 Issue: 5 Pages: 530-536 Special Issue: SI, 2015
    Hunter, FW (Hunter, Francis W.)[ 1 ] ; Young, RJ (Young, Richard J.)[ 2,3 ] ; Shalev, Z (Shalev, Zvi)[ 4 ] ; Vellanki, RN (Vellanki, Ravi N.)[ 4 ] ; Wang, JL (Wang, Jingli)[ 1 ] ; Gu, YC (Gu, Yongchuan)[ 1,5 ] ; Joshi, N (Joshi, Naveen)[ 1 ] ; Sreebhavan, S (Sreebhavan, Sreevalsan)[ 1 ] ; Weinreb, I (Weinreb, Ilan)[ 4 ] ; Goldstein, DP (Goldstein, David P.)[ 6 ] ; Moffat, J (Moffat, Jason)[ 7 ] ; Ketela, T (Ketela, Troy)[ 8,9 ] ; Brown, KR (Brown, Kevin R.)[ 8,9 ] ; Koritzinsky, M (Koritzinsky, Marianne)[ 4,7,10 ] ; Solomon, B (Solomon, Benjamin)[ 2,3,11 ] ; Rischin, D (Rischin, Danny)[ 3,11 ] ; Wilson, WR (Wilson, William R.); Wouters, BG Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs CANCER RESEARCH Volume: 75 Issue: 19 Pages: 4211-4223, 2015
    Spugnini, EP (Spugnini, Enrico Pierluigi)[ 1 ] ; Sonveaux, P (Sonveaux, Pierre)[ 2 ] ; Stock, C (Stock, Christian)[ 3 ] ; Perez-Sayans, M (Perez-Sayans, Mario)[ 4 ] ; De Milito, A (De Milito, Angelo)[ 5 ] ; Avnet, S (Avnet, Sofia)[ 6 ] ; Garcia, AG (Garcia Garcia, Abel)[ 4 ] ; Harguindey, S (Harguindey, Salvador)[ 7 ] ; Fais, S Proton channels and exchangers in cancer BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES Volume: 1848 Issue: 10 Pages: 2715-2726 Part: B Special Issue: SI, 2015
    Mahon, BP (Mahon, Brian P.)[ 1 ] ; Lomelino, CL (Lomelino, Carrie L.)[ 1 ] ; Ladwig, J (Ladwig, Janina)[ 2 ] ; Rankin, GM (Rankin, Gregory M.)[ 2 ] ; Driscoll, JM (Driscoll, Jenna M.)[ 1 ] ; Salguero, AL (Salguero, Antonieta L.)[ 1 ] ; Pinard, MA (Pinard, Melissa A.)[ 1 ] ; Vullo, D (Vullo, Daniela)[ 3,4 ] ; Supuran, CT (Supuran, Claudiu T.)[ 3,4 ] ; Poulsen, SA (Poulsen, Sally-Ann)[ 2 ] ; McKenna, R Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates JOURNAL OF MEDICINAL CHEMISTRY olume: 58 Issue: 16 Pages: 6630-6638, 2015
    Kim, YJ (Kim, Yu Jeong)[ 1 ] ; Liu, YR (Liu, Yarong)[ 2 ] ; Li, S (Li, Si)[ 1 ] ; Rohrs, J (Rohrs, Jennifer)[ 3 ] ; Zhang, R (Zhang, Rachel)[ 3 ] ; Zhang, XY (Zhang, Xiaoyang)[ 2 ] ; Wang, P Co-Eradication of Breast Cancer Cells and Cancer Stem Cells by Cross-Linked Multi lamellar Liposomes Enhances Tumor Treatment MOLECULAR PHARMACEUTICS Volume: 12 Issue: 8 Pages: 2811-2822 Special Issue: SI , 2015
    Fraga, A (Fraga, Avelino)[ 1,2,3 ] ; Ribeiro, R (Ribeiro, Ricardo)[ 3,4,5,6 ] ; Prnicipe, P (Principe, Paulo)[ 1,3 ] ; Lopes, C (Lopes, Carlos)[ 2 ] ; Medeiros, R Hypoxia and Prostate Cancer Aggressiveness: A Tale With Many Endings CLINICAL GENITOURINARY CANCER Volume: 13 Issue: 4 Pages: 295-301, 2015
    Wang, GQ (Wang, Guanqiao)[ 1 ] ; Cheng, ZG (Cheng, Zhenguo)[ 1 ] ; Liu, FA (Liu, Funan)[ 2 ] ; Zhang, HY (Zhang, Hongyan)[ 1 ] ; Li, JB (Li, Jiabin)[ 1 ] ; Li, F CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancer CELLULAR SIGNALLING Volume: 27 Issue: 7 Pages: 1369-1379, 2015
    Verduzco, D (Verduzco, Daniel)[ 1 ] ; Lloyd, M (Lloyd, Mark)[ 2 ] ; Xu, LP (Xu, Liping)[ 1 ] ; Ibrahim-Hashim, A (Ibrahim-Hashim, Arig)[ 1 ] ; Balagurunathan, Y (Balagurunathan, Yoganand)[ 1 ] ; Gatenby, RA (Gatenby, Robert A.)[ 3 ] ; Gillies, RJ Intermittent Hypoxia Selects for Genotypes and Phenotypes That Increase Survival, Invasion, and Therapy Resistance PLOS ONE Volume: 10 Issue: 3 Article Number: e0120958, 2015
    Perez-Sayans, M (Perez-Sayans, M.)[ 1 ] ; Suarez-Penaranda, JM (Suarez-Penaranda, J. M.)[ 2,3 ] ; Torres-Lopez, M (Torres-Lopez, M.)[ 1 ] ; Supuran, CT (Supuran, C. T.)[ 4 ] ; Gandara-Vila, P (Gandara-Vila, P.)[ 1 ] ; Gayoso-Diz, P (Gayoso-Diz, P.)[ 5 ] ; Barros-Angueira, F (Barros-Angueira, F.)[ 6 ] ; Gallas-Torreira, M (Gallas-Torreira, M.)[ 1 ] ; Garcia-Garcia, A The use of CA-IX as a diagnostic method for oral leukoplakia BIOTECHNIC & HISTOCHEMISTRY Volume: 90 Issue: 2 Pages: 124-131, 2015
    Mahon, BP (Mahon, Brian P.)[ 1 ] ; Pinard, MA (Pinard, Melissa A.)[ 1 ] ; McKenna, R Targeting Carbonic Anhydrase IX Activity and Expression MOLECULES Volume: 20 Issue: 2 Pages: 2323-2348, 2015
    De Donato, M (De Donato, Marta)[ 1 ] ; Fanelli, M (Fanelli, Mara)[ 2 ] ; Mariani, M (Mariani, Marisa)[ 3 ] ; Raspaglio, G (Raspaglio, Giuseppina)[ 1 ] ; Pandya, D (Pandya, Deep)[ 3 ] ; He, SQ (He, Shiquan)[ 3 ] ; Fiedler, P (Fiedler, Paul)[ 3 ] ; Petrillo, M (Petrillo, Marco)[ 1 ] ; Scambia, G (Scambia, Giovanni)[ 1 ] ; Ferlini, C Nek6 and Hif-1 alpha cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer AMERICAN JOURNAL OF CANCER RESEARCH Volume: 5 Issue: 6 Pages: 1862-1877, 2015
    Jiang, J (Jiang, J.)[ 1,2 ] ; Zhao, JH (Zhao, J. H.)[ 2 ] ; Wang, XL (Wang, X. L.)[ 3 ] ; Guo, XJ (Guo, X. J.)[ 4 ] ; Yang, J (Yang, J.)[ 2 ] ; Bai, X (Bai, X.)[ 2 ] ; Jin, SY (Jin, S. Y.)[ 2 ] ; Ge, RL Correlation between carbonic anhydrase IX (CA-9), XII (CA-12) and hypoxia inducible factor-2 alpha (HIF-2 alpha) in breast cancer NEOPLASMA Volume: 62 Issue: 3 Pages: 456-463, 2015
    Pinard, MA (Pinard, Melissa A.)[ 1 ] ; Mahon, B (Mahon, Brian)[ 1 ] ; McKenna, R Probing the Surface of Human Carbonic Anhydrase for Clues towards the Design of Isoform Specific Inhibitors BIOMED RESEARCH INTERNATIONAL Article Number: 453543, 2015
    Ng, HLH (Ng, Huei Leng Helena)[ 1 ] ; Lu, AP (Lu, Aiping)[ 1,2 ] ; Lin, G (Lin, Ge)[ 3 ] ; Qin, L (Qin, Ling)[ 4 ] ; Yang, ZJ The Potential of Liposomes with Carbonic Anhydrase IX to Deliver Anticancer Ingredients to Cancer Cells in Vivo INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume: 16 Issue: 1 Pages: 230-255, 2015
    Jögi, A. Tumour hypoxia and the hypoxia-inducible transcription factors: Key players in cancer progression and metastasis Tumor Cell Metabolism: Pathways, Regulation and Biology 1 January 2015, Pages 65-98
    MORRISON, Eamonn - WAI, Patty - LEONIDOU, Andri - BLAND, Philip - KHALIQUE, Saira - FARNIE, Gillian - DALEY, Frances - PECK, Barrie - NATRAJAN, Rachael. Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures. In JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. ISSN 1940-087X, DEC 2016, no. 118.
    PARK, Ga-Young - HAN, Yu Kyeong - HAN, Jeong Yoon - LEE, Chang Geun. Tauroursodeoxycholic acid reduces the invasion of MDA-MB-231 cells by modulating matrix metalloproteinases 7 and 13. In ONCOLOGY LETTERS. ISSN 1792-1074, SEP 2016, vol. 12, no. 3, p. 2227-2231.
    XIAO, Bin - CHEN, Daxiang - LUO, Shuhong - HAO, Wenbo - JING, Fangyan - LIU, Tiancai - WANG, Suihai - GENG, Yan - LI, Linhai - XU, Weiwen - ZHANG, Yajie - LIAO, Xiaoqing - ZUO, Daming - WU, Yingsong - LI, Ming - MA, Qiang. Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/MMP9 signaling. In ONCOTARGET. ISSN 1949-2553, AUG 2 2016, vol. 7, no. 31, p. 50057-50073.
    JIN, Min-Sun - LEE, Hyebin - PARK, In Ae - CHUNG, Yul Ri - IM, Seock-Ah - LEE, Kyung-Hun - MOON, Hyeong-Gon - HAN, Wonshik - KIM, Kyubo - KIM, Tae-Yong - NOH, Dong-Young - RYU, Han Suk. Overexpression of HIF1 alpha and CAXI predicts poor outcome in early-stage triple negative breast cancer. In VIRCHOWS ARCHIV. ISSN 0945-6317, AUG 2016, vol. 469, no. 2, p. 183-190.
    LOMELINO, Carrie - MCKENNA, Robert. Carbonic anhydrase inhibitors: a review on the progress of patent literature (2011-2016). In EXPERT OPINION ON THERAPEUTIC PATENTS. ISSN 1354-3776, AUG 2016, vol. 26, no. 8, p. 947-956.
    AUSLANDER, Noam - YIZHAK, Keren - WEINSTOCK, Adam - BUDHU, Anuradha - TANG, Wei - WANG, Xin Wei - AMBS, Stefan - RUPPIN, Eytan. A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer. In SCIENTIFIC REPORTS. ISSN 2045-2322, JUL 13 2016, vol. 6.
    LV, Peng-Cheng - PUTT, Karson S. - LOW, Philip S. Evaluation of Nonpeptidic Ligand Conjugates for SPECT Imaging of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers. In BIOCONJUGATE CHEMISTRY. ISSN 1043-1802, JUL 2016, vol. 27, no. 7, p. 1762-1769.
    SAMAKA, Rehab M. - ABD EL-WAHED, Moshira M. - AL SHARAKY, Dalia R. - SHEHATA, Mohamed A. - HEGAZY, Shaymaa E. - ALESKANDARANY, Andmohammed A. Overexpression of Carbonic Anhydrase IX is a Dismal Prognostic Marker in Breast Carcinoma in Egyptian Patients. In APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY. ISSN 1541-2016, JUL 2016, vol. 24, no. 6, p. 405-413.
    LV, Peng-Cheng - ROY, Jyoti - PUTT, Karson S. - LOW, Philip S. Evaluation of a Carbonic Anhydrase IX-Targeted Near-Infrared Dye for Fluorescence-Guided Surgery of Hypoxic Tumors. In MOLECULAR PHARMACEUTICS. ISSN 1543-8384, MAY 2016, vol. 13, no. 5, p. 1618-1625.
    ZHANG, Xi - CHEN, Lirong. The recent progress of the mechanism and regulation of tumor necrosis in colorectal cancer. In JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. ISSN 0171-5216, FEB 2016, vol. 142, no. 2, p. 453-463.
    GRITLI, Ismael - GARMEY, Edward - ELIASOF, Scott - TELLEZ, Andres - DAVIS, Mark E. - YUN, Yen. Polymeric Nanoparticles and Cancer: Lessons Learnt from CRLX101. In NANOMEDICINES: DESIGN, DELIVERY AND DETECTION. ISSN 2041-3203, 2016, no. 51, p. 199-232.
    CHU, Xia - ZHAO, Po - LV, Yali - LIU, Lin. Expression of carbonic anhydrase-9 correlates with metastasis and prognosis of Chinese patients with invasive breast ductal carcinoma. In INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY. ISSN 1936-2625, 2016, vol. 9, no. 2, p. 1446-1452.
    BROWN-GLABERMAN, Ursa - MARRON, Marilyn - CHALASANI, Pavani - LIVINGSTON, Robert - IANNONE, Maria - SPECHT, Jennifer - STOPECK, Alison T. Circulating Carbonic Anhydrase IX and Antiangiogenic Therapy in Breast Cancer. In DISEASE MARKERS. ISSN 0278-0240, 2016.
    EOM, Keun-Yong - JANG, Min Hye - PARK, So Yeon - KANG, Eun Young - KIM, Sung Won - KIM, Jee Hyun - KIM, Jae-Sung - KIM, In Ah. The Expression of Carbonic Anhydrase (CA) IX/XII and Lymph Node Metastasis in Early Breast Cancer. In CANCER RESEARCH AND TREATMENT. ISSN 1598-2998, JAN 2016, vol. 48, no. 1, p. 125-132.
    TAKAHASHI, Hidekazu - SUZUKI, Yozo - NISHIMURA, Junichi - HARAGUCHI, Naotsugu - OHTSUKA, Masahisa - MIYAZAKI, Susumu - UEMURA, Mamoru - HATA, Taishi - TAKEMASA, Ichiro - MIZUSHIMA, Tsunekazu - YAMAMOTO, Hirofumi - DOKI, Yuichiro - MORI, Masaki. Characteristics of carbonic anhydrase 9 expressing cells in human intestinal crypt base. In INTERNATIONAL JOURNAL OF ONCOLOGY. ISSN 1019-6439, JAN 2016, vol. 48, no. 1, p. 115-122.
    CHU, Cheng-Yu - JIN, Yi-Ting - ZHANG, Wei - YU, Juan - YANG, Hai-Ping - WANG, Hong-Ying - ZHANG, Zi-Jing - LIU, Xiu-Ping - ZOU, Qiang. CA IX is upregulated in CoCl2-induced hypoxia and associated with cell invasive potential and a poor prognosis of breast cancer. In INTERNATIONAL JOURNAL OF ONCOLOGY. ISSN 1019-6439, JAN 2016, vol. 48, no. 1, p. 271-280.
    KUNKLER, Ian H. - WARD, Carol - SPEERS, Corey - PIERCE, Lori - FENG, Felix - MEEHAN, James - LANGDON, Simon P. Personalisation of radiotherapy for breast cancer. In Personalized Treatment of Breast Cancer, 2016-01-01, pp. 131-149.
    ANGAPELLY, Srinivas - RAMYA, P. V. Sri - ANGELI, Andrea - SUPURAN, Claudiu T. - ARIFUDDIN, Mohammed. Sulfocoumarin-, Coumarin-, 4-Sulfamoylphenyl-Bearing Indazole-3-carboxamide Hybrids: Synthesis and Selective Inhibition of Tumor-Associated Carbonic Anhydrase Isozymes IX and XII. In CHEMMEDCHEM. ISSN 1860-7179, 2017, vol. 12, no. 19, pp. 1578-1584.
    HYUGA, Satoshi - WADA, Hiroshi - EGUCHI, Hidetoshi - OTSURU, Toru - IWGAMI, Yoshifumi - YAMADA, Daisaku - NODA, Takehiro - ASAOKA, Tadafumi - KAWAMOT, Koichi - GOTOH, Kunihito - TAKEDA, Yutaka - TANEMURA, Masahiro - UMESHITA, Koji - DOKI, Yuichiro - MORI, Masaki. Expression of carbonic anhydrase IX is associated with poor prognosis through regulation of the epithelial-mesenchymal transition in hepatocellular carcinoma. In INTERNATIONAL JOURNAL OF ONCOLOGY. ISSN 1019-6439, 2017, vol. 51, no. 4, pp. 1179-1190.
    HAN, Jian - LI, Jia - HO, Jolene Caifeng - CHIA, Grace Sushin - KATO, Hiroyuki - JHA, Sudhakar - YANG, Henry - POELLINGER, Lorenz - LEE, Kian Leong. Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells. In SCIENTIFIC REPORTS. ISSN 2045-2322, 2017, vol. 7, no., pp. 10-26.
    SAKA, Burcu - EKINCI, Ozgur - DURSUN, Ayse - AKYUREK, Nalan. Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1 alpha, CXCR4 and CA9 in colorectal carcinoma. In PATHOLOGY RESEARCH AND PRACTICE. ISSN 0344-0338, 2017, vol. 213, no. 7, pp. 783-792.
    CHALLAPALLI, Amarnath - CARROLL, Laurence - ABOAGYE, Eric O. Molecular mechanisms of hypoxia in cancer. In CLINICAL AND TRANSLATIONAL IMAGING. ISSN 2281-5872, 2017, vol. 5, no. 3, pp. 225-253.
    EL GUERRAB, Abderrahim - CAYRE, Anne - KWIATKOWSKI, Fabrice - PRIVAT, Maud - ROSSIGNOL, Jean-Marc - ROSSIGNOL, Fabrice - PENAULT-LLORCA, Frederique - BIGNON, Yves-Jean. Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancer. In PLOS ONE. ISSN 1932-6203, 2017, vol. 12, no. 4, pp.
    AALDERS, Kim C. - TRYFONIDIS, Konstantinos - SENKUS, Elbieta - CARDOSO, Fatima. Anti-angiogenic treatment in breast cancer: Facts, successes, failures and future perspectives. In CANCER TREATMENT REVIEWS. ISSN 0305-7372, 2017, vol. 53, no., pp. 98-110.
    SUPURAN, Claudiu T. Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors. In EXPERT OPINION ON INVESTIGATIONAL DRUGS. ISSN 1354-3784, 2018, vol. 27, no. 12, pp. 963-970.
    MIKUS, Peter - KRAJCIOVA, Dominika - MIKULOVA, Maria - HORVATH, Branislav - PECHER, Daniel - GARAJ, Vladimir - BUA, Silvia - ANGELI, Andrea - SUPURAN, Claudiu T. Novel sulfonamides incorporating 1,3,5-triazine and amino acid structural motifs as inhibitors of the physiological carbonic anhydrase isozymes I, II and IV and tumor-associated isozyme IX. In BIOORGANIC CHEMISTRY. ISSN 0045-2068, 2018, vol. 81, no., pp. 241-252.
    BOZDAG, Murat - CARTA, Fabrizio - CERUSO, Mariangela - FERRARONI, Marta - MCDONALD, Paul C. - DEDHAR, Shoukat - SUPURAN, Claudiu T. Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX. In JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623, 2018, vol. 61, no. 14, pp. 6328-6338.
    CHEN, Zhijuan - AI, Lingbao - MBOGE, Mam Y. - TU, Chingkuang - MCKENNA, Robert - BROWN, Kevin D. - HELDERMON, Coy D. - FROST, Susan C. Differential expression and function of CAIX and CAXII in breast cancer: A comparison between tumorgraft models and cells. In PLOS ONE. ISSN 1932-6203, 2018, vol. 13, no. 7, pp.
    CETIN, Bulent - GONUL, Ipek Isik - GUMUSAY, Ozge - BILGETEKIN, Irem - ALGIN, Efnan - OZET, Ahmet - UNER, Aytug. Carbonic anhydrase IX is a prognostic biomarker in glioblastoma multiforme. In NEUROPATHOLOGY. ISSN 0919-6544, 2018, vol. 38, no. 5, pp. 457-462.
    SIEGERS, Gabrielle M. - DUTTA, Indrani - LAI, Raymond - POSTOVIT, Lynne-Marie. Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia. In FRONTIERS IN IMMUNOLOGY. ISSN 1664-3224, 2018, vol. 9, no., pp.
    TORRES LOPEZ, Manuel - PEREZ SAYANS, Mario - CHAMORRO PETRONACCI, Cintia - BARROS ANGUEIRA, Francisco - GANDARA VILA, Pilar - LORENZO POUSO, Alejandro - GARCIA GARCIA, Abel. Determination and diagnostic value of CA9 mRNA in peripheral blood of patients with oral leukoplakia. In JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. ISSN 1475-6366, 2018, vol. 33, no. 1, pp. 951-955.
    MARKS, Isaac S. - GARDEEN, Spencer S. - KURDZIEL, Sarah J. - NICOLAOU, Sonia T. - WOODS, J. Evan - KULARATNE, Sumith A. - LOW, Philip S. Development of a Small Molecule Tubulysin B Conjugate for Treatment of Carbonic Anhydrase IX Receptor Expressing Cancers. In MOLECULAR PHARMACEUTICS. ISSN 1543-8384, 2018, vol. 15, no. 6, pp. 2289-2296.
    SUPURAN, Claudiu T. - ALTERIO, Vincenzo - DI FIORE, Anna - D' AMBROSIO, Katia - CARTA, Fabrizio - MONTI, Simona Maria - DE SIMONE, Giuseppina. Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one. In MEDICINAL RESEARCH REVIEWS. ISSN 0198-6325, 2018, vol. 38, no. 6, pp. 1799-1836.
    WARD, Carol - MEEHAN, James - GRAY, Mark - KUNKLER, Ian H. - LANGDON, Simon P. - ARGYLE, David J. Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness. In METABOLITES. ISSN 2218-1989, 2018, vol. 8, no. 1, pp.
    CHEN, Zhijuan - AI, Lingbao - MBOGE, Mam Y. - MCKENNA, Robert - FROST, Christopher J. - HELDERMON, Coy D. - FROST, Susan C. UFH-001 cells: A novel triple negative, CAIX-positive, human breast cancer model system. In CANCER BIOLOGY & THERAPY. ISSN 1538-4047, 2018, vol. 19, no. 7, pp. 598-608.
    MORE, Kunal N. - LEE, Jun Young - KIM, Dong-Yeon - CHO, Nam-Chul - PYO, Ayoung - YUN, Misun - KIM, Hyeon Sik - KIM, Hangun - KO, Kwangseok - PARK, Jeong-Hoon - CHANG, Dong-Jo. Acetazolamide-based [F-18]-PET tracer: In vivo validation of carbonic anhydrase IX as a sole target for imaging of CA-IX expressing hypoxic solid tumors. In BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. ISSN 0960-894X, 2018, vol. 28, no. 5, pp. 915-921.
    WIJESEKERA, Dj - WILLIS, Scott A. - GUPTA, Abhishek - TORRES, Allan M. - ZHENG, Gang - PRICE, William S. NMR diffusion and relaxation studies of 2-nitroimidazole and albumin interactions. In SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY. ISSN 1386-1425, 2018, vol. 193, no., pp. 318-323.
    MORE, Tushar H. - ROYCHOUDHURY, Sourav - CHRISTIE, Joel - TAUNK, Khushman - MANE, Anupama - SANTRA, Manas K. - CHAUDHURY, Koel - RAPOLE, Srikanth. Metabolomic alterations in invasive ductal carcinoma of breast: A comprehensive metabolomic study using tissue and serum samples. In ONCOTARGET, 2018, vol. 9, no. 2, pp. 2678-2696.
    TIFFON, Celine. Histone Deacetylase Inhibition Restores Expression of Hypoxia-Inducible Protein NDRG1 in Pancreatic Cancer. In PANCREAS. ISSN 0885-3177, 2018, vol. 47, no. 2, pp. 200-207.
    NAKAMURA, Hiroshi - ICHIKAWA, Tomohiro - NAKASONE, Shoko - MIYOSHI, Tomohiro - SUGANO, Masato - KOJIMA, Motohiro - FUJII, Satoshi - OCHIAI, Atsushi - KUWATA, Takeshi - AOKAGE, Keiju - SUZUKI, Kenji - TSUBOI, Masahiro - ISHII, Genichiro. Abundant tumor promoting stromal cells in lung adenocarcinoma with hypoxic regions. In LUNG CANCER. ISSN 0169-5002, 2018, vol. 115, no., pp. 56-63.
    SHABANA, Ahmed M. - ILIES, Marc A. Drug Delivery to Hypoxic Tumors Targeting Carbonic Anhydrase IX. In TARGETED NANOSYSTEMS FOR THERAPEUTIC APPLICATIONS: NEW CONCEPTS, DYNAMIC PROPERTIES, EFFICIENCY, AND TOXICITY. ISSN 0097-6156, 2019, vol. 1309, no., pp. 223-252.
    PECK, Barrie - SCHULZE, Almut. Lipid Metabolism at the Nexus of Diet and Tumor Microenvironment. In TRENDS IN CANCER. ISSN 2405-8025, 2019, vol. 5, no. 11, pp. 693-703.
    UDA, Narasimha Rao - STENNER, Frank - SEIBERT, Volker - HERZIG, Petra - MARKULY, Norbert - VAN DIJK, Marc - ZIPPELIUS, Alfred - RENNER, Christoph. Humanized Monoclonal Antibody Blocking Carbonic Anhydrase 12 Enzymatic Activity Leads to Reduced Tumor Growth In Vitro. In ANTICANCER RESEARCH. ISSN 0250-7005, 2019, vol. 39, no. 8, pp. 4117-4128.
    STRAVINSKIENE, Dovile - IMBRASAITE, Aiste - PETRIKAITE, Vilma - MATULIS, Daumantas - MATULIENE, Jurgita - ZVIRBLIENE, Aurelija. New Monoclonal Antibodies for a Selective Detection of Membrane-Associated and Soluble Forms of Carbonic Anhydrase IX in Human Cell Lines and Biological Samples. In BIOMOLECULES, 2019, vol. 9, no. 8, pp.
    POSPISILOVA, Klara - KNEDLIK, Tomas - SACHA, Pavel - KOSTKA, Libor - SCHIMER, Jiri - BRYNDA, Jiri - KRAL, Vlastimil - CIGLER, Petr - NAVRATIL, Vaclav - ETRYCH, Tomas - SUBR, Vladimir - KUGLER, Michael - FABRY, Milan - REZACOVA, Pavlina - KONVALINKA, Jan. Inhibitor-Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms. In ACS OMEGA. ISSN 2470-1343, 2019, vol. 4, no. 4, pp. 6746-6756.
    REIJNEN, Casper - VAN WEELDEN, Willem Jan - ARTS, Martijn S. J. P. - PETERS, Johan P. - RIJKEN, Paul F. - VAN DE VIJVER, Koen - SANTACANA, Maria - BRONSERT, Peter - BULTEN, Johan - HIRSCHFELD, Marc - COLAS, Eva - GIL-MORENO, Antonio - REQUES, Armando - MANCEBO, Gemma - KRAKSTAD, Camilla - TROVIK, Jone - HALDORSEN, Ingfrid S. - HUVILA, Jutta - KOSKAS, Martin - WEINBERGER, Vit - MINAR, Lubos - JANDAKOVA, Eva - SNIJDERS, Marc P. L. M. - VAN DEN BERG-VAN ERP, Saskia - KUSTERS-VANDEVELDE, Heidi V. N. - MATIAS-GUIU, Xavier - AMANT, Frederic - MASSUGER, Leon F. A. G. - BUSSINK, Johan - PIJNENBORG, Johanna M. A. Poor outcome in hypoxic endometrial carcinoma is related to vascular density. In BRITISH JOURNAL OF CANCER. ISSN 0007-0920, 2019, vol. 120, no. 11, pp. 1037-1044.
    COWMAN, Sophie - FAN, Yuen Ngan - PIZER, Barry - SEE, Violaine. Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells. In BMC CANCER. ISSN 1471-2407, 2019, vol. 19, no., pp.
    GUETTLER, Antje - THEUERKORN, Katharina - RIEMANN, Anne - WICHMANN, Henri - KESSLER, Jacqueline - THEWS, Oliver - BACHE, Matthias - VORDERMARK, Dirk. Cellular and radiobiological effects of carbonic anhydrase IX in human breast cancer cells. In ONCOLOGY REPORTS. ISSN 1021-335X, 2019, vol. 41, no. 4, pp. 2585-2594.
    JANNING, Melanie - MUELLER, Volkmar - VETTORAZZI, Eik - CUBAS-CORDOVA, Miguel - GENSCH, Victoria - BEN-BATALLA, Isabel - ZU EULENBURG, Christine - SCHEM, Christian - FASCHING, Peter A. - SCHNAPPAUF, Benjamin - KARN, Thomas - FEHM, Tanja - JUST, Marianne - KUEHN, Thorsten - HOLMS, Frank - OVERKAMP, Friedrich - KRABISCH, Petra - RACK, Brigitte - DENKERT, Carsten - UNTCH, Michael - TESCH, Hans - REZAI, Mahdi - KITTEL, Kornelia - PANTEL, Klaus - BOKEMEYER, Carsten - LOIBL, Sibylle - VON MINCKWITZ, Gunter - LOGES, Sonja. Evaluation of soluble carbonic anhydrase IX as predictive marker for efficacy of bevacizumab: A biomarker analysis from the geparquinto phase III neoadjuvant breast cancer trial. In INTERNATIONAL JOURNAL OF CANCER. ISSN 0020-7136, 2019, vol. 145, no. 3, pp. 857-868.
    OHTAKI, Yoichi - SHIMIZU, Kimihiro - KAWABATA-IWAKAWA, Reika - GOMBODORJ, Navchaa - ALTAN, Bolag - ROKUDAI, Susumu - YAMANE, Arito - KAIRA, Kyoichi - YOKOBORI, Takehiko - NAGASHIMA, Toshiteru - OBAYASHI, Kai - NAKAZAWA, Seshiru - IIJIMA, Misaki - KOSAKA, Takayuki - YAJIMA, Toshiki - MOGI, Akira - KUWANO, Hiroyuki - SHIRABE, Ken - NISHIYAMA, Masahiko. Carbonic anhydrase 9 expression is associated with poor prognosis, tumor proliferation, and radiosensitivity of thymic carcinomas. In Oncotarget, 2019-02-01, 10, 13, pp. 1306-1319.
    VENKATESWARAN, G. - DEDHAR, S. Interplay of Carbonic Anhydrase IX With Amino Acid and Acid/Base Transporters in the Hypoxic Tumor Microenvironment. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, NOV 9 2020, vol. 8.
    SHIN, U.C. - CHOI, J.S. - BEAK, Y.J. - LEE, M.W. - KIM, H.S. - CHOI, D.W. - KIM, D.G. - KIM, S.W. Development of a Ga-68-labelled PET tracer for carbonic anhydrase IX-overexpressed tumors using the artificial sweetener saccharin. In JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. ISSN 0362-4803, MAR 2021, vol. 64, no. 3, p. 129-139.
    SARNELLA, A. - D'AVINO, G. - HILL, B.S. - ALTERIO, V. - WINUM, J.Y. - SUPURAN, C.T. - DE SIMONE, G. - ZANNETTI, A. A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. NOV 2020, vol. 21, no. 21.
    ANGELI, A. - CARTA, F. - NOCENTINI, A. - WINUM, J.Y. - ZALUBOVSKIS, R. - AKDEMIR, A. - ONNIS, V. - ELDEHNA, W.M. - CAPASSO, C. - DE SIMONE, G. - MONTI, S.M. - CARRADORI, S. - DONALD, W.A. - DEDHAR, S. - SUPURAN, C.T. Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment. In METABOLITES. OCT 2020, vol. 10, no. 10.
    MALEBARI, A.M. - IBRAHIM, T.S. - SALEM, I.M. - SALAMA, I. - KHAYYAT, A.N. - MOSTAFA, S.M. - EL-SABBAGH, O.I. - DARWISH, K.M. The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme. In PHARMACEUTICALS. SEP 2020, vol. 13, no. 9.
    DVORANOVA, J. - KUGLER, M. - HOLUB, J. - SICHA, V. - DAS, V. - NEKVINDA, J. - EL ANWAR, S. - HAVRANEK, M. - POSPISILOVA, K. - FABRY, M. - KRAL, V. - MEDVEDIKOVA, M. - MATEJKOVA, S. - LISKOVA, B. - GURSKA, S. - DZUBAK, P. - BRYNDA, J. - HAJDUCH, M. - GRUNER, B. - REZACOVA, P. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. In EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0223-5234, AUG 15 2020, vol. 200.
    CAO, Q. - ZHOU, D.J. - PAN, Z.Y. - YANG, G.G. - ZHANG, H. - JI, L.N. - MAO, Z.W. CAIXplatins: Highly Potent Platinum(IV) Prodrugs Selective Against Carbonic Anhydrase IX for the Treatment of Hypoxic Tumors. In ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. ISSN 1433-7851, OCT 12 2020, vol. 59, no. 42, p. 18556-18562.
    CARMONA-BOZO, J.C. - MANAVAKI, R. - WOITEK, R. - TORHEIM, T. - BAXTER, G.C. - CARACO, C. - PROVENZANO, E. - GRAVES, M.J. - FRYER, T.D. - PATTERSON, A.J. - GILBERT, F.J. Hypoxia and perfusion in breast cancer: simultaneous assessment using PET/MR imaging. In EUROPEAN RADIOLOGY. ISSN 0938-7994, JAN 2021, vol. 31, no. 1, p. 333-344.
    LEE, S.H. - GRIFFITHS, J.R. How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH. In CANCERS. JUN 2020, vol. 12, no. 6.
    VERMEULEN, M.A. - VAN DEURZEN, C.H.M. - SCHRODER, C.P. - MARTENS, J.W.M. - VAN DIEST, P.J. Expression of hypoxia-induced proteins in ductal carcinoma in situ and invasive cancer of the male breast. In JOURNAL OF CLINICAL PATHOLOGY. ISSN 0021-9746, APR 2020, vol. 73, no. 4, p. 204-208.
    LI, S.M. - TAN, L.F. - MENG, X.W. Nanoscale Metal-Organic Frameworks: Synthesis, Biocompatibility, Imaging Applications, and Thermal and Dynamic Therapy of Tumors. In ADVANCED FUNCTIONAL MATERIALS. ISSN 1616-301X, MAR 2020, vol. 30, no. 13.
    ZHANG, X.L. - LIU, X.Y. - CUI, W.W. - ZHANG, R.H. - LIU, Y. - LI, Y.K. - HAO, J. Sohlh2 alleviates malignancy of EOC cells under hypoxia via inhibiting the HIF1 alpha/CA9 signaling pathway. In BIOLOGICAL CHEMISTRY. ISSN 1431-6730, FEB 2020, vol. 401, no. 2, p. 263-271.
    MACHIAVELLI, N. Carbonic anhydrases. In INNOVATIVE APPROACH TO UNDERSTANDING AND TREATING CANCER: TARGETING PH: From Etiopathogenesis to New Therapeutic Avenues. 2020, p. 157-176.
    DINARVAND, N. - KHANAHMAD, H. - HAKIMIAN, S.M. - SHEIKHI, A. - RASHIDI, B. - POURFARZAM, M. Evaluation of long-chain acyl-coenzyme A synthetase 4 (ACSL4) expression in human breast cancer. In RESEARCH IN PHARMACEUTICAL SCIENCES. ISSN 1735-5362, JAN-FEB 2020, vol. 15, no. 1, p. 48-56.
    TAKACOVA, M. - BARATHOVA, M. - ZATOVICOVA, M. - GOLIAS, T. - KAJANOVA, I. - JELENSKA, L. - SEDLAKOVA, O. - SVASTOVA, E. - KOPACEK, J. - PASTOREKOVA, S. Carbonic Anhydrase IX-Mouse versus Human. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. JAN 1 2020, vol. 21, no. 1.
    BIAMONTI, G. - INFANTINO, L. - GAGLIO, D. - AMATO, A. An Intricate Connection between Alternative Splicing and Phenotypic Plasticity in Development and Cancer. In CELLS. JAN 2020, vol. 9, no. 1.
    MA, Z.Y. - YUAN, D.M. - CHENG, X.M. - TUO, B.G. - LIU, X.M. - LI, T.L. Function of ion transporters in maintaining acid-base homeostasis of the mammary gland and the pathophysiological role in breast cancer. In AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. ISSN 0363-6119, JAN 2020, vol. 318, no. 1, p. R98-R111.
    SUPURAN, C.T. Carbonic anhydrase inhibitors: an update on experimental agents for the treatment and imaging of hypoxic tumors. In EXPERT OPINION ON INVESTIGATIONAL DRUGS. ISSN 1354-3784, DEC 2 2021, vol. 30, no. 12, p. 1197-1208. Dostupné na: https://doi.org/10.1080/13543784.2021.2014813.
    DAI, H.J. - SHENG, X.N. - WANG, Y.H. - ZHOU, L.H. - LIN, Y.P. - DU, Y.Y. - YANG, F. - SHA, R. - PENG, J. - YAO, L.L. - YIN, W.J. - LU, J.S. HIF1 alpha Regulates IL17 Signaling Pathway Influencing Sensitivity of Taxane-Based Chemotherapy for Breast Cancer. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, SEP 14 2021, vol. 9. Dostupné na: https://doi.org/10.3389/fcell.2021.729965.
    DI FIORE, A. - SUPURAN, C.T. - SCALONI, A. - DE SIMONE, G. Post-translational modifications in tumor-associated carbonic anhydrases. In AMINO ACIDS. ISSN 0939-4451, APR 2022, vol. 54, no. 4, SI, p. 543-558. Dostupné na: https://doi.org/10.1007/s00726-021-03063-y.
    CHAFE, S.C. - VIZEACOUMAR, F.S. - VENKATESWARAN, G. - NEMIROVSKY, O. - AWREY, S. - BROWN, W.S. - MCDONALD, P.C. - CARTA, F. - METCALFE, A. - KARASINSKA, J.M. - HUANG, L. - MUTHUSWAMY, S.K. - SCHAEFFER, D.F. - RENOUF, D.J. - SUPURAN, C.T. - VIZEACOUMAR, F.J. - DEDHAR, S. Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors. In SCIENCE ADVANCES. ISSN 2375-2548, AUG 2021, vol. 7, no. 35. Dostupné na: https://doi.org/10.1126/sciadv.abj0364.
    GUTTLER, A. - EISELT, Y. - FUNTAN, A. - THIEL, A. - PETRENKO, M. - KESSLER, J. - THONDORF, I. - PASCHKE, R. - VORDERMARK, D. - BACHE, M. Betulin Sulfonamides as Carbonic Anhydrase Inhibitors and Anticancer Agents in Breast Cancer Cells. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. AUG 2021, vol. 22, no. 16. Dostupné na: https://doi.org/10.3390/ijms22168808.
    PEERZADA, M.N. - HAMEL, E. - BAI, R.L. - SUPURAN, C.T. - AZAM, A. Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development. In PHARMACOLOGY & THERAPEUTICS. ISSN 0163-7258, SEP 2021, vol. 225. Dostupné na: https://doi.org/10.1016/j.pharmthera.2021.107860.
    CHAFE, S.C. - RIAZ, N. - BURUGU, S. - GAO, D.X. - LEUNG, S.C.Y. - LEE, A.F. - LEE, C.H. - DEDHAR, S. - NIELSEN, T.O. Granulocyte Colony Stimulating Factor Expression in Breast Cancer and Its Association with Carbonic Anhydrase IX and Immune Checkpoints. In CANCERS. MAR 2021, vol. 13, no. 5. Dostupné na: https://doi.org/10.3390/cancers13051022.
    MBOGE, M.Y. - COMBS, J. - SINGH, S. - ANDRING, J. - WOLFF, A. - TU, C.K. - ZHANG, Z.H. - MCKENNA, R. - FROST, S.C. Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer. In JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623, FEB 11 2021, vol. 64, no. 3, p. 1713-1724. Dostupné na: https://doi.org/10.1021/acs.jmedchem.0c02077.
    KCIUK, M. - GIELECINSKA, A. - MUJWAR, S. - MOJZYCH, M. - MARCINIAK, B. - DROZDA, R. - KONTEK, R. Targeting carbonic anhydrase IX and XII isoforms with small molecule inhibitors and monoclonal antibodies. In JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. ISSN 1475-6366, DEC 31 2022, vol. 37, no. 1, p. 1278-1298. Dostupné na: https://doi.org/10.1080/14756366.2022.2052868.
    SAID, M.F. - GEORGE, R.F. - PETRENI, A. - SUPURAN, C.T. - MOHAMED, N.M. Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity. In JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. ISSN 1475-6366, DEC 31 2022, vol. 37, no. 1, p. 701-717. Dostupné na: https://doi.org/10.1080/14756366.2022.2036137.
    ABDEL-MOHSEN, H.T. - EL KERDAWY, A.M. - PETRENI, A. - SUPURAN, C.T. Novel benzenesulfonamide-thiouracil conjugates with a flexible N-ethyl acetamide linker as selective CA IX and CA XII inhibitors. In ARCHIV DER PHARMAZIE. ISSN 0365-6233, FEB 2023, vol. 356, no. 2. Dostupné na: https://doi.org/10.1002/ardp.202200434.
    HARRIS, B. - SALEEM, S. - COOK, N. - SEARLE, E. Targeting hypoxia in solid and haematological malignancies. In JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. NOV 2 2022, vol. 41, no. 1. Dostupné na: https://doi.org/10.1186/s13046-022-02522-y.
    NGUYEN, P.L. - ELKAMHAWY, A. - CHOI, Y.H. - LEE, C.H. - LEE, K. - CHO, J. Suppression of Tumor Growth and Cell Migration by Indole-Based Benzenesulfonamides and Their Synergistic Effects in Combination with Doxorubicin. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. SEP 2022, vol. 23, no. 17. Dostupné na: https://doi.org/10.3390/ijms23179903.
    ASPATWAR, A. - TOLVANEN, M.E.E. - BARKER, H. - SYRJANEN, L. - VALANNE, S. - PURMONEN, S. - WAHEED, A. - SLY, W.S. - PARKKILA, S. CARBONIC ANHYDRASES IN METAZOAN MODEL ORGANISMS: MOLECULES, MECHANISMS, AND PHYSIOLOGY. In PHYSIOLOGICAL REVIEWS. ISSN 0031-9333, JUL 2022, vol. 102, no. 3, p. 1327-1383. Dostupné na: https://doi.org/10.1152/physrev.00018.2021.
    ONG, C.H.C. - LEE, D.Y. - LEE, B. - LI, H.H. - LIM, J.C.T. - LIM, J.X. - YEONG, J.P.S. - LAU, H.Y. - THIKE, A.A. - TAN, P.H. - IQBAL, J. Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer. In BREAST CANCER RESEARCH. ISSN 1465-5411, JUN 3 2022, vol. 24, no. 1. Dostupné na: https://doi.org/10.1186/s13058-022-01532-0.
    LIU, Y. - KONG, X.X. - HE, J.J. - XU, Y.B. - ZHANG, J.K. - ZOU, L.Y. - DING, K.F. - XU, D. OLA1 promotes colorectal cancer tumorigenesis by activation of HIF1 alpha/CA9 axis. In BMC CANCER. APR 19 2022, vol. 22, no. 1. Dostupné na: https://doi.org/10.1186/s12885-022-09508-1.
    RYNIAWEC, J.M. - COOPE, M.R. - LOERTSCHER, E. - BAGEERATHAN, V. - PESSOA, D.D. - WARFEL, N.A. - CRESS, A.E. - PADI, M. - ROGERS, G.C. GLUT3/SLC2A3 Is an Endogenous Marker of Hypoxia in Prostate Cancer Cell Lines and Patient-Derived Xenograft Tumors. In DIAGNOSTICS. MAR 2022, vol. 12, no. 3. Dostupné na: https://doi.org/10.3390/diagnostics12030676.
    HADADI, E. - DESCHOEMAEKER, S. - VENEGAS, G.V. - LAOUI, D. Heterogeneity and function of macrophages in the breast during homeostasis and cancer. In ONE, NO ONE, ONE HUNDRED THOUSAND - THE MULTIFACETED ROLE OF MACROPHAGES IN HEALTH AND DISEASE, PT A. ISSN 1937-6448, 2022, vol. 367, A, p. 149-182. Dostupné na: https://doi.org/10.1016/bs.ircmb.2022.01.002.
    KOLTAI, T. The complex relationship between multiple drug resistance and the tumor pH gradient: a review. In CANCER DRUG RESISTANCE. 2022, vol. 5, no. 2, p. 277-303. Dostupné na: https://doi.org/10.20517/cdr.2021.134.
    KategóriaADCA - Vedecké práce v zahraničných karentovaných časopisoch impaktovaných
    Kategória (od 2022)V3 - Vedecký výstup publikačnej činnosti z časopisu
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    Rok vykazovania2001
    Registrované vWOS
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    200120008.773
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