Počet záznamov: 1
Probing sporadic and familial Alzheimer´s disease using induced pluripotent stem cells
Názov Probing sporadic and familial Alzheimer´s disease using induced pluripotent stem cells Autor Israel M.A. Herrera C. Hefferan Michael P. Maršala Martin 1961 SAVNEBIO - Neurobiologický ústav SAV Spoluautori Yuan S.H. Bardy C. Reyna S.M. Mu Y. Van Gorp S. Nazor K.L. Boscolo F.S. Carson C.T. Laurent L.C. Gage F.H. Remes A.M. Koo E.H. Goldstein L.S.B. Zdroj.dok. Nature. Vol. 482, no. 7384 (2012), p. 216-226 Jazyk dok. eng - angličtina Krajina GB - Veľká Británia Druh dok. rozpis článkov z periodík (rbx) Ohlasy HIRATA, Shinji - TAKAYAMA, Naoya - JONO-OHNISHI, Ryoko - ENDO, Hiroshi - NAKAMURA, Sou - DOHDA, Takeaki - NISHI, Masanori - HAMAZAKI, Yuhei - ISHII, Ei-ichi - KANEKO, Shin - OTSU, Makoto - NAKAUCHI, Hiromitsu - KUNISHIMA, Shinji - ETO, Koji. Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling. In JOURNAL OF CLINICAL INVESTIGATION. ISSN 0021-9738, SEP 2013, vol. 123, no. 9, p. 3802-3814. ALMEIDA, Sandra - GASCON, Eduardo - TRAN, Helene - CHOU, Hsin Jung - GENDRON, Tania F. - DEGROOT, Steven - TAPPER, Andrew R. - SELLIER, Chantal - CHARLET-BERGUERAND, Nicolas - KARYDAS, Anna - SEELEY, William W. - BOXER, Adam L. - PETRUCELLI, Leonard - MILLER, Bruce L. - GAO, Fen-Biao. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. In ACTA NEUROPATHOLOGICA. ISSN 0001-6322, SEP 2013, vol. 126, no. 3, p. 385-399. NAKANISHI, Nobuki - RYAN, Scott D. - ZHANG, Xiaofei - KHAN, Adnan - HOLLAND, Timothy - CHO, Eun-Gyung - HUANG, Xiayu - LIAO, Francesca-Fang - XU, Huaxi - LIPTON, Stuart A. - TU, Shichun. Synaptic Protein alpha 1-Takusan Mitigates Amyloid-beta-Induced Synaptic Loss via Interaction with Tau and Postsynaptic Density-95 at Postsynaptic Sites. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, AUG 28 2013, vol. 33, no. 35, p. 14170-14183. MOREL, Etienne - CHAMOUN, Zeina - LASIECKA, Zofia M. - CHAN, Robin B. - WILLIAMSON, Rebecca L. - VETANOVETZ, Christopher - DALL'ARMI, Claudia - SIMOES, Sabrina - DU JOUR, Kimberly S. Point - MCCABE, Brian D. - SMALL, Scott A. - DI PAOLO, Gilbert. Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system. In NATURE COMMUNICATIONS. ISSN 2041-1723, AUG 2013, vol. 4. MCINTIRE, Laura Beth J. - LANDMAN, Natalie - KANG, Min Suk - FINAN, Gina M. - HWANG, Jeremy C. - MOORE, Ann Z. - PARK, Lydia S. - LIN, Chyuan-Sheng - KIM, Tae-Wan. Phenotypic Assays for beta-Amyloid in Mouse Embryonic Stem Cell-Derived Neurons. In CHEMISTRY & BIOLOGY. ISSN 1074-5521, JUL 25 2013, vol. 20, no. 7, p. 956-967. GALIMBERTI, Daniela - SCARPINI, Elio. Progress in Alzheimer's disease research in the last year. In JOURNAL OF NEUROLOGY. ISSN 0340-5354, JUL 2013, vol. 260, no. 7, p. 1936-1941. TURAC, Gizem - HINDLEY, Christopher J. - THOMAS, Ria - DAVIS, Jason A. - DELEIDI, Michela - GASSER, Thomas - KARAOZ, Erdal - PRUSZAK, Jan. Combined Flow Cytometric Analysis of Surface and Intracellular Antigens Reveals Surface Molecule Markers of Human Neuropoiesis. In PLOS ONE. ISSN 1932-6203, JUN 24 2013, vol. 8, no. 6. ZHANG, Yingsha - PAK, ChangHui - HAN, Yan - AHLENIUS, Henrik - ZHANG, Zhenjie - CHANDA, Soham - MARRO, Samuele - PATZKE, Christopher - ACUNA, Claudio - COVY, Jason - XU, Wei - YANG, Nan - DANKO, Tamas - CHEN, Lu - WERNIG, Marius - SUEDHOF, Thomas C. Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells. In NEURON. ISSN 0896-6273, JUN 5 2013, vol. 78, no. 5, p. 785-798. YUAN, Shauna H. - SHANER, Mason. Bioengineered stem cells in neural development and neurodegeneration research. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, JUN 2013, vol. 12, no. 3, SI, p. 739-748. JONSON, Ida - OUGLAND, Rune - LARSEN, Elisabeth. DNA Repair Mechanisms in Huntington's Disease. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, JUN 2013, vol. 47, no. 3, p. 1093-1102. GARATE, Zita - DAVIS, Brian R. - QUINTANA-BUSTAMANTE, Oscar - SEGOVIA, Jose C. New Frontier in Regenerative Medicine: Site-Specific Gene Correction in Patient-Specific Induced Pluripotent Stem Cells. In HUMAN GENE THERAPY. ISSN 1043-0342, JUN 2013, vol. 24, no. 6, p. 571-583. XU, Xiao-hong - ZHONG, Zhong. Disease modeling and drug screening for neurological diseases using human induced pluripotent stem cells. In ACTA PHARMACOLOGICA SINICA. ISSN 1671-4083, JUN 2013, vol. 34, no. 6, p. 755-764. MARCELLO, Elena - SARACENO, Claudia - MUSARDO, Stefano - VARA, Hugo - DE LA FUENTE, Alerie Guzman - PELUCCHI, Silvia - DI MARINO, Daniele - BORRONI, Barbara - TRAMONTANO, Anna - PEREZ-OTANO, Isabel - PADOVANI, Alessandro - GIUSTETTO, Maurizio - GARDONI, Fabrizio - DI LUCA, Monica. Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. In JOURNAL OF CLINICAL INVESTIGATION. ISSN 0021-9738, JUN 2013, vol. 123, no. 6, p. 2523-2538. LI, Rui - BAI, Ye - LIU, Tongtong - WANG, Xiaoqun - WU, Qian. Induced pluripotency and direct reprogramming: a new window for treatment of neurodegenerative diseases. In PROTEIN & CELL. ISSN 1674-800X, JUN 2013, vol. 4, no. 6, p. 415-424. RIZZO, Stacey J. Sukoff - EDGERTON, Jeremy R. - HUGHES, Zoe A. - BRANDON, Nicholas J. Future Viable Models of Psychiatry Drug Discovery in Pharma. In JOURNAL OF BIOMOLECULAR SCREENING. ISSN 1087-0571, JUN 2013, vol. 18, no. 5, p. 509-521. FERREIRA, Leonardo M. R. - MOSTAJO-RADJI, Mohammed A. How induced pluripotent stem cells are redefining personalized medicine. In GENE. ISSN 0378-1119, MAY 10 2013, vol. 520, no. 1, p. 1-6. SCOTT, Clay W. - PETERS, Matthew F. - DRAGAN, Yvonne P. Human induced pluripotent stem cells and their use in drug discovery for toxicity testing. In TOXICOLOGY LETTERS. ISSN 0378-4274, MAY 10 2013, vol. 219, no. 1, p. 49-58. YAWO, Hiromu - ASANO, Toshifumi - SAKAI, Seiichiro - ISHIZUKA, Toru. Optogenetic manipulation of neural and non-neural functions. In DEVELOPMENT GROWTH & DIFFERENTIATION. ISSN 0012-1592, MAY 2013, vol. 55, no. 4, p. 474-490. GLAT, Micaela Johanna - OFFEN, Daniel. Cell and Gene Therapy in Alzheimer's Disease. In STEM CELLS AND DEVELOPMENT. ISSN 1547-3287, MAY 2013, vol. 22, no. 10, p. 1490-1496. HALES, Chadwick M. - HU, William T. From frontotemporal lobar degeneration pathology to frontotemporal lobar degeneration biomarkers. In INTERNATIONAL REVIEW OF PSYCHIATRY. ISSN 0954-0261, APR 2013, vol. 25, no. 2, p. 210-220. SILLER, Richard - GREENHOUGH, Sebastian - PARK, In-Hyun - SULLIVAN, Gareth J. Modelling Human Disease with Pluripotent Stem Cells. In CURRENT GENE THERAPY. ISSN 1566-5232, APR 2013, vol. 13, no. 2, p. 99-110. ANJAMROOZ, Seyed Hadi. The Cellular Memory Disc of Reprogrammed Cells. In STEM CELL REVIEWS AND REPORTS. ISSN 1550-8943, APR 2013, vol. 9, no. 2, p. 190-209. MACKAY-SIM, Alan. Patient-derived stem cells: pathways to drug discovery for brain diseases. In FRONTIERS IN CELLULAR NEUROSCIENCE. ISSN 1662-5102, MAR 27 2013, vol. 7. XU, Xiaohong - LEI, Ying - LUO, Jie - WANG, Jamie - ZHANG, Shu - YANG, Xiu-Juan - SUN, Mu - NUWAYSIR, Emile - FAN, Guohuang - ZHAO, Jing - LEI, Lei - ZHONG, Zhong. Prevention of beta-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events. In STEM CELL RESEARCH. ISSN 1873-5061, MAR 2013, vol. 10, no. 2, p. 213-227. LOMBINO, Franco - BIUNDO, Fabrizio - TAMAYEV, Robert - ARANCIO, Ottavio - D'ADAMIO, Luciano. An Intracellular Threonine of Amyloid-beta Precursor Protein Mediates Synaptic Plasticity Deficits and Memory Loss. In PLOS ONE. ISSN 1932-6203, FEB 22 2013, vol. 8, no. 2. TELESE, Francesca - GAMLIE, Amir - SKOWRONSKA-KRAWCZYK, Dorota - GARCIA-BASSETS, Ivan - ROSENFELD, Michael G. "Seq-ing" Insights into the Epigenetics of Neuronal Gene Regulation. In NEURON. ISSN 0896-6273, FEB 20 2013, vol. 77, no. 4, p. 606-623. NOBREGA MARINHO, Paulo Andre - VARESCHINI, Daniel Tait - GOMES, Ismael Carlos - PAULSEN, Bruna da Silveira - FURTADO, Daniel Rodrigues - CASTILHO, Leda dos Reis - REHEN, Stevens Kastrup. Xeno-Free Production of Human Embryonic Stem Cells in Stirred Microcarrier Systems Using a Novel Animal/Human-Component-Free Medium. In TISSUE ENGINEERING PART C-METHODS. ISSN 1937-3384, FEB 2013, vol. 19, no. 2, p. 146-155. EGASHIRA, Toru - YUASA, Shinsuke - FUKUDA, Keiichi. Novel Insights into Disease Modeling Using Induced Pluripotent Stem Cells. In BIOLOGICAL & PHARMACEUTICAL BULLETIN. ISSN 0918-6158, FEB 2013, vol. 36, no. 2, p. 182-188. SINGH, Ruchira - SHEN, Wei - KUAI, David - MARTIN, Jessica M. - GUO, Xiangrong - SMITH, Molly A. - PEREZ, Enio T. - PHILLIPS, M. Joseph - SIMONETT, Joseph M. - WALLACE, Kyle A. - VERHOEVEN, Amelia D. - CAPOWSKI, Elizabeth E. - ZHANG, Xiaoqing - YIN, Yingnan - HALBACH, Patrick J. - FISHMAN, Gerald A. - WRIGHT, Lynda S. - PATTNAIK, Bikash R. - GAMM, David M. iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, FEB 1 2013, vol. 22, no. 3, p. 593-607. KAZMEROVA, Zuzana - ZILKA, Norbert - CENTE, Martin - NERADIL, Peter - ZILKOVA, Monika - NOVAK, Michal. Can We Teach Old Dogs New Tricks? Neuroprotective Cell Therapy in Alzheimer's and Parkinson's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 37, no. 2, p. 251-272. RAMON LACADENA, Juan. Rewinding the genetic film of development. In ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA. ISSN 1697-4271, 2013, vol. 79, no. 1, p. 151-171. BHAT, Narayan R. - THIRUMANGALAKUDI, Lakshmi. Increased Tau Phosphorylation and Impaired Brain Insulin/IGF Signaling in Mice Fed a High Fat/High Cholesterol Diet. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 36, no. 4, p. 781-789. BUTZKE, Daniel - GRUNE, Barbara - KUGLER, Josephine - OELGESCHLAEGER, Michael - SEILER, Andrea - SITTNER, Dana - LIEBSCH, Manfred - LUCH, Andreas. The Advent of the Golden Era of Animal Alternatives. In ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE. 2013, p. 49-73. CHEN, Mengqi - KRETZSCHMAR, Doris - VERDILE, Giuseppe - LARDELLI, Michael. Models of Alzheimer's Disease. In ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE. 2013, p. 595-632. GARCIA-ESCUDERO, Vega - MARTIN-MAESTRO, Patricia - PERRY, George - AVILA, Jesus. Deconstructing Mitochondrial Dysfunction in Alzheimer Disease. In OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. ISSN 1942-0900, 2013. WOJDA, Urszula - KUZNICKI, Jacek. Alzheimer's Disease Modeling: Ups, Downs, and Perspectives for Human Induced Pluripotent Stem Cells. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 34, no. 3, p. 563-588. FROESTL, Wolfgang - PFEIFER, Andrea - MUHS, Andreas. Cognitive Enhancers (Nootropics). Part 3: Drugs Interacting with Targets other than Receptors or Enzymes. Disease-modifying Drugs. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 34, no. 1, p. 1-114. GAO, Aijing - PENG, Yuhua - DENG, Yulin - QING, Hong. POTENTIAL THERAPEUTIC APPLICATIONS OF DIFFERENTIATED INDUCED PLURIPOTENT STEM CELLS (iPSCS) IN THE TREATMENT OF NEURODEGENERATIVE DISEASES. In NEUROSCIENCE. ISSN 0306-4522, JAN 2013, vol. 228, p. 47-59. OOI, Lezanne - SIDHU, Kuldip - POLJAK, Anne - SUTHERLAND, Greg - O'CONNOR, Michael D. - SACHDEV, Perminder - MUENCH, Gerald. Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer's disease. In JOURNAL OF NEURAL TRANSMISSION. ISSN 0300-9564, JAN 2013, vol. 120, no. 1, SI, p. 103-111. WANG, Lihui - WANG, Linli - HUANG, Wenhao - SU, Huanxing - XUE, Yanting - SU, Zhenghui - LIAO, Baojian - WANG, Haitao - BAO, Xichen - QIN, Dajiang - HE, Jufang - WU, Wutian - SO, Kwok Fai - PAN, Guangjin - PEI, Duanqing. Generation of integration-free neural progenitor cells from cells in human urine. In NATURE METHODS. ISSN 1548-7091, JAN 2013, vol. 10, no. 1, p. 84-U124. BETTENS, Karolien - SLEEGERS, Kristel - VAN BROECKHOVEN, Christine. Genetic insights in Alzheimer's disease. In LANCET NEUROLOGY. ISSN 1474-4422, JAN 2013, vol. 12, no. 1, p. 92-104. CHIRILA, Florin V. - KHAN, Tapan K. - ALKON, Daniel L. Spatiotemporal Complexity of Fibroblast Networks Screens for Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2013, vol. 33, no. 1, p. 165-176. GARCIA, Isabella - KIM, Cynthia - ARENKIEL, Benjamin R. Genetic strategies to investigate neuronal circuit properties using stem cell-derived neurons. In FRONTIERS IN CELLULAR NEUROSCIENCE. ISSN 1662-5102, DEC 18 2012, vol. 6. TAMAYEV, Robert - AKPAN, Nsikan - ARANCIO, Ottavio - TROY, Carol M. - D'ADAMIO, Luciano. Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, DEC 10 2012, vol. 7. LIU, Guang-Hui - DING, Zhichao - IZPISUA BELMONTE, Juan Carlos. iPSC technology to study human aging and aging-related disorders. In CURRENT OPINION IN CELL BIOLOGY. ISSN 0955-0674, DEC 2012, vol. 24, no. 6, p. 765-774. CHEN, Wesley W. - BLURTON-JONES, Mathew. Concise Review: Can Stem Cells Be Used to Treat Or Model Alzheimer's Disease?. In STEM CELLS. ISSN 1066-5099, DEC 2012, vol. 30, no. 12, p. 2612-2618. DIEKMAN, Brian O. - CHRISTOFOROU, Nicolas - WILLARD, Vincent P. - SUN, Haosi - SANCHEZ-ADAMS, Johannah - LEONG, Kam W. - GUILAK, Farshid. Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells. In PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ISSN 0027-8424, NOV 20 2012, vol. 109, no. 47, p. 19172-19177. SEIDEL, Diana - KRINKE, Dana - JAHNKE, Heinz-Georg - HIRCHE, Anika - KLOSS, Daniel - MACK, Till G. A. - STRIGGOW, Frank - ROBITZKI, Andrea. Induced Tauopathy in a Novel 3D-Culture Model Mediates Neurodegenerative Processes: A Real-Time Study on Biochips. In PLOS ONE. ISSN 1932-6203, NOV 7 2012, vol. 7, no. 11. BROECKEL, Ulrich - MARESSO, Karen. Genetics, genomics and the power of stem cells to identify novel treatment options in complex diseases. In PERSONALIZED MEDICINE. ISSN 1741-0541, NOV 2012, vol. 9, no. 8, p. 821-828. SCHONROCK, Nicole - GOETZ, Juergen. Decoding the non-coding RNAs in Alzheimer's disease. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, NOV 2012, vol. 69, no. 21, p. 3543-3559. PANICKER, Leelamma M. - MILLER, Diana - PARK, Tea Soon - PATEL, Brijesh - AZEVEDO, Judi L. - AWAD, Ola - MASOOD, M. Athar - VEENSTRA, Timothy D. - GOLDIN, Ehud - STUBBLEFIELD, Barbara K. - TAYEBI, Nahid - POLUMURI, Swamy K. - VOGEL, Stefanie N. - SIDRANSKY, Ellen - ZAMBIDIS, Elias T. - FELDMAN, Ricardo A. Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease. In PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ISSN 0027-8424, OCT 30 2012, vol. 109, no. 44, p. 18054-18059. PETERS, Derek T. - MUSUNURU, Kiran. Functional evaluation of genetic variation in complex human traits. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, OCT 15 2012, vol. 21, 1, p. R18-R23. TOKUTAKE, Takayoshi - KASUGA, Kensaku - YAJIMA, Ryuji - SEKINE, Yumi - TEZUKA, Toshiyuki - NISHIZAWA, Masatoyo - IKEUCHI, Takeshi. Hyperphosphorylation of Tau Induced by Naturally Secreted Amyloid-beta at Nanomolar Concentrations Is Modulated by Insulin-dependent Akt-GSK3 beta Signaling Pathway. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, OCT 12 2012, vol. 287, no. 42, p. 35222-35233. LANE, Rachel F. - ST GEORGE-HYSLOP, Peter - HEMPSTEAD, Barbara L. - SMALL, Scott A. - STRITTMATTER, Stephen M. - GANDY, Sam. Vps10 Family Proteins and the Retromer Complex in Aging-Related Neurodegeneration and Diabetes. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, OCT 10 2012, vol. 32, no. 41, p. 14080-14086. ALMEIDA, Sandra - ZHANG, Zhijun - COPPOLA, Giovanni - MAO, Wenjie - FUTAI, Kensuke - KARYDAS, Anna - GESCHWIND, Michael D. - TARTAGLIA, M. Carmela - GAO, Fuying - GIANNI, Davide - SENA-ESTEVES, Miguel - GESCHWIND, Daniel H. - MILLER, Bruce L. - FARESE, Robert V., Jr. - GAO, Fen-Biao. Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects. In CELL REPORTS. ISSN 2211-1247, OCT 2012, vol. 2, no. 4, p. 789-798. SHI, Yichen - KIRWAN, Peter - LIVESEY, Frederick J. Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. In NATURE PROTOCOLS. ISSN 1754-2189, OCT 2012, vol. 7, no. 10, p. 1836-1846. ONDER, Tamer T. - DALEY, George Q. New lessons learned from disease modeling with induced pluripotent stem cells. In CURRENT OPINION IN GENETICS & DEVELOPMENT. ISSN 0959-437X, OCT 2012, vol. 22, no. 5, p. 500-508. HARTFIELD, Elizabeth M. - FERNANDES, Hugo J. R. - VOWLES, Jane - COWLEY, Sally A. - WADE-MARTINS, Richard. Cellular reprogramming: a new approach to modelling Parkinson's disease. In BIOCHEMICAL SOCIETY TRANSACTIONS. ISSN 0300-5127, OCT 2012, vol. 40, 5, p. 1152-1157. HAYTHORNTHWAITE, Alison - STOELZLE, Sonja - HASLER, Alexander - KISS, Andrea - MOSBACHER, Johannes - GEORGE, Michael - BRUEGGEMANN, Andrea - FERTIG, Niels. Characterizing Human Ion Channels in Induced Pluripotent Stem Cell-Derived Neurons. In JOURNAL OF BIOMOLECULAR SCREENING. ISSN 1087-0571, OCT 2012, vol. 17, no. 9, SI, p. 1264-1272. DEVALLE, Sylvie - SARTORE, Rafaela C. - PAULSEN, Bruna S. - BORGES, Helena L. - MARTINS, Rodrigo A. P. - REHEN, Stevens K. Implications of aneuploidy for stem cell biology and brain therapeutics. In FRONTIERS IN CELLULAR NEUROSCIENCE. ISSN 1662-5102, SEP 5 2012, vol. 6. WRAY, Selina - SELF, Matthew - LEWIS, Patrick A. - TAANMAN, Jan-Willem - RYAN, Natalie S. - MAHONEY, Colin J. - LIANG, Yuying - DEVINE, Michael J. - SHEERIN, Una-Marie - HOULDEN, Henry - MORRIS, Huw R. - HEALY, Daniel - MARTI-MASSO, Jose-Felix - PREZA, Elisavet - BARKER, Suzanne - SUTHERLAND, Margaret - CORRIVEAU, Roderick A. - D'ANDREA, Michael - SCHAPIRA, Anthony H. V. - UITTI, Ryan J. - GUTTMAN, Mark - OPALA, Grzegorz - JASINSKA-MYGA, Barbara - PUSCHMANN, Andreas - NILSSON, Christer - ESPAY, Alberto J. - SLAWEK, Jaroslaw - GUTMANN, Ludwig - BOEVE, Bradley F. - BOYLAN, Kevin - STOESSL, A. Jon - ROSS, Owen A. - MARAGAKIS, Nicholas J. - VAN GERPEN, Jay - GERSTENHABER, Melissa - GWINN, Katrina - DAWSON, Ted M. - ISACSON, Ole - MARDER, Karen S. - CLARK, Lorraine N. - PRZEDBORSKI, Serge E. - FINKBEINER, Steven - ROTHSTEIN, Jeffrey D. - WSZOLEK, Zbigniew K. - ROSSOR, Martin N. - HARDY, John. Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research. In PLOS ONE. ISSN 1932-6203, AUG 27 2012, vol. 7, no. 8. ITO, Daisuke - OKANO, Hideyuki - SUZUKI, Norihiro. Accelerating progress in induced pluripotent stem cell research for neurological diseases. In ANNALS OF NEUROLOGY. ISSN 0364-5134, AUG 2012, vol. 72, no. 2, p. 167-174. YAO, Zhao-hui - ZHANG, Jun-jian - XIE, Xiao-feng. Enriched Environment Prevents Cognitive Impairment and Tau hyperphosphorylation after Chronic Cerebral Hypoperfusion. In CURRENT NEUROVASCULAR RESEARCH. ISSN 1567-2026, AUG 2012, vol. 9, no. 3, p. 176-184. COSSEC, Jack-Christophe - LAVAUR, Jeremie - BERMAN, Diego E. - RIVALS, Isabelle - HOISCHEN, Alexander - STORA, Samantha - RIPOLL, Clementine - MIRCHER, Clotilde - GRATTAU, Yann - OLIVOMARIN, Jean-Christophe - DE CHAUMONT, Fabrice - LECOURTOIS, Magalie - ANTONARAKIS, Stylianos E. - VELTMAN, Joris A. - DELABAR, Jean M. - DUYCKAERTS, Charles - DI PAOLO, Gilbert - POTIER, Marie-Claude. Trisomy for Synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, JUL 15 2012, vol. 21, no. 14, p. 3156-3172. RING, Karen L. - TONG, Leslie M. - BALESTRA, Maureen E. - JAVIER, Robyn - ANDREWS-ZWILLING, Yaisa - LI, Gang - WALKER, David - ZHANG, William R. - KREITZER, Anatol C. - HUANG, Yadong. Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor. In CELL STEM CELL. ISSN 1934-5909, JUL 6 2012, vol. 11, no. 1, p. 100-109. COOPER, Oliver - SEO, Hyemyung - ANDRABI, Shaida - GUARDIA-LAGUARTA, Cristina - GRAZIOTTO, John - SUNDBERG, Maria - MCLEAN, Jesse R. - CARRILLO-REID, Luis - XIE, Zhong - OSBORN, Teresia - HARGUS, Gunnar - DELEIDI, Michela - LAWSON, Tristan - BOGETOFTE, Helle - PEREZ-TORRES, Eduardo - CLARK, Lorraine - MOSKOWITZ, Carol - MAZZULLI, Joseph - CHEN, Li - VOLPICELLI-DALEY, Laura - ROMERO, Norma - JIANG, Houbo - UITTI, Ryan J. - HUANG, Zhigao - OPALA, Grzegorz - SCARFFE, Leslie A. - DAWSON, Valina L. - KLEIN, Christine - FENG, Jian - ROSS, Owen A. - TROJANOWSKI, John Q. - LEE, Virginia M. -Y. - MARDER, Karen - SURMEIER, D. James - WSZOLEK, Zbigniew K. - PRZEDBORSKI, Serge - KRAINC, Dimitri - DAWSON, Ted M. - ISACSON, Ole. Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease. In SCIENCE TRANSLATIONAL MEDICINE. ISSN 1946-6234, JUL 4 2012, vol. 4, no. 141. DREWS, Katharina - JOZEFCZUK, Justyna - PRIGIONE, Alessandro - ADJAYE, James. Human induced pluripotent stem cells-from mechanisms to clinical applications. In JOURNAL OF MOLECULAR MEDICINE-JMM. ISSN 0946-2716, JUL 2012, vol. 90, no. 7, p. 735-745. BHALLA, Akhil - VETANOVETZ, Christopher P. - MOREL, Etienne - CHAMOUN, Zeina - DI PAOLO, Gilbert - SMALL, Scott A. The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, JUL 2012, vol. 47, no. 1, p. 126-134. ORR, Miranda E. - PITSTICK, Rose - CANINE, Brenda - ASHE, Karen H. - CARLSON, George A. Genotype-Specific Differences between Mouse CNS Stem Cell Lines Expressing Frontotemporal Dementia Mutant or Wild Type Human Tau. In PLOS ONE. ISSN 1932-6203, JUN 18 2012, vol. 7, no. 6. YAMANAKA, Shinya. Induced Pluripotent Stem Cells: Past, Present, and Future. In CELL STEM CELL. ISSN 1934-5909, JUN 14 2012, vol. 10, no. 6, p. 678-684. ROMANO, G. LATEST ADVANCES IN iPS CELL TECHNOLOGY: TOWARD THE DELINEATION OF THE GENETIC AND EPIGENETIC CODES FOR PLURIPOTENCY AND DEVELOPMENT OF A NOVEL SYSTEM FOR THE STUDY OF HUMAN MALADIES AND DRUG SCREENING. In DRUGS OF THE FUTURE. ISSN 0377-8282, JUN 2012, vol. 37, no. 6, p. 431-435. PIMENTEL-COELHO, Pedro M. - RIVEST, Serge. The early contribution of cerebrovascular factors to the pathogenesis of Alzheimer's disease. In EUROPEAN JOURNAL OF NEUROSCIENCE. ISSN 0953-816X, JUN 2012, vol. 35, no. 12, SI, p. 1917-1937. BYERS, Blake - LEE, Hsiao-lu - PERA, Renee Reijo. Modeling Parkinson's Disease Using Induced Pluripotent Stem Cells. In CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS. ISSN 1528-4042, JUN 2012, vol. 12, no. 3, p. 237-242. JUOPPERI, Tarja A. - KIM, Woon Ryoung - CHIANG, Cheng-Hsuan - YU, Huimei - MARGOLIS, Russell L. - ROSS, Christopher A. - MING, Guo-li - SONG, Hongjun. Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells. In MOLECULAR BRAIN. ISSN 1756-6606, MAY 21 2012, vol. 5. CHEN, Zhao - ZHAO, Tongbiao - XU, Yang. The genomic stability of induced pluripotent stem cells. In PROTEIN & CELL. ISSN 1674-800X, APR 2012, vol. 3, no. 4, p. 271-277. HUANG, Yadong - MUCKE, Lennart. Alzheimer Mechanisms and Therapeutic Strategies. In CELL. ISSN 0092-8674, MAR 16 2012, vol. 148, no. 6, p. 1204-1222. SHI, Yichen - KIRWAN, Peter - SMITH, James - MACLEAN, Glenn - ORKIN, Stuart H. - LIVESEY, Frederick J. A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome. In SCIENCE TRANSLATIONAL MEDICINE. ISSN 1946-6234, MAR 7 2012, vol. 4, no. 124. CHOI, Se Hoon - TANZI, Rudolph E. iPSCs to the Rescue in Alzheimer's Research. In CELL STEM CELL. ISSN 1934-5909, MAR 2 2012, vol. 10, no. 3, p. 235-236. ZHANG, Weiqi - DUAN, Shunlei - LI, Ying - XU, Xiuling - QU, Jing - ZHANG, Weizhou - LIU, Guang-Hui. Converted neural cells: induced to a cure?. In PROTEIN & CELL. ISSN 1674-800X, FEB 2012, vol. 3, no. 2, p. 91-97. GALASKO, Douglas - GOLDE, Todd - WILCOCK, Gordon. Recent Alzheimer's disease research highlights. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2012, vol. 4, no. 3. LIVESEY, Frederick J. Stem cell models of Alzheimer's disease and related neurological disorders. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2012, vol. 4, no. 6. XIA, Weiming - WONG, Stephen T. - HANLON, Eugene - MORIN, Peter. gamma-Secretase Modulator in Alzheimer's Disease: Shifting the End. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2012, vol. 31, no. 4, p. 685-696. WANG, Hansen - DOERING, Laurie C. Induced Pluripotent Stem Cells to Model and Treat Neurogenetic Disorders. In NEURAL PLASTICITY. ISSN 0792-8483, 2012. BHAT, N. R.- THIRUMANGALAKUDI, L. Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet. In JOURNAL OF ALZHEIMER'S DISEASE. ISSN 1387-2877 , 2013, vol. 36, no.4, p. 781-789. GALIMBERTI, D.- SCARPINI, E. Progress in alzheimer's disease research in the last year. In JOURNAL OF NEUROLOGY. ISSN 0340-5354,2013, vol.260, no.7, p.1936-1941. GARCÍA-ESCUDERO, V.- MARTÍN-MAESTRO, P.- PERRY, G.- AVILA, J. Deconstructing mitochondrial dysfunction in alzheimer disease. In OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. ISSN1942-0900, 2013, art. no. 162152 . IACONE, R.- ANSON, B. Patient in a dish. In EBR - EUROPEAN BIOPHARMACEUTICAL REVIEW, (WINTER), ISSN1369-0663, 2013, p.56-60 JIAO, J.- YANG, Y.- SHI, Y.- CHEN, J.-GAO, R.- FAN, Y.- GAO, S. Modeling dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, 2013, vol. 22, no.21,p. 4241-4252. LACADENA, J. R. Rewinding the genetic film of development. [Rebobinando la película genética del desarrollo] In ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA. ISSN 0034-0618, 2013, vol. 79, no.1, p.151-171. LIPPMANN, E. S.- AL-AHMAD, A.- PALECEK, S. P.- SHUSTA, E. V. Modeling the blood-brain barrier using stem cell sources. In FLUIDS AND BARRIERS OF THE CNS. ISSN 2045-8118, 2013, vol.10, no. 1, art. no. 2. MARINHO, P. A. N.-VARESCHINI, D. T.-GOMES, I. C.- PAULSEN, B. D. S.- FURTADO, D. R.- CASTILHO, L. D. R.- REHEN, S. K. Xeno-free production of human embryonic stem cells in stirred microcarrier systems using a novel animal/human-component-free medium. In TISSUE ENGINEERING - PART C: METHODS. ISSN 1937-3384, 2013, vol.19, no.2, p. 146-155. MARTIN, B.- CHEN, H.- DAIMON, C. M.- CHADWICK, W.- SIDDIQUI, S.- MAUDSLEY, S. Plurigon: Three dimensional visualization and classification of highdimensionality data. In FRONTIERS IN PHYSIOLOGY. ISSN 1664-042X, 2013, art. no. Article 190. MCKERNAN, R.- WATT, F. M. What is the point of large-scale collections of human induced pluripotent stem cells? In NATURE BIOTECHNOLOGY. ISSN 1087-0156, 2013, vol. 31, no.10, p. 875-877. MERKLE, F. T.- EGGAN, K. Modeling human disease with pluripotent stem cells: From genome association to function. In CELL STEM CELL. ISSN 1934-5909, 2013, vol.12, no.6, p.656-668. QIANG, L.- FUJITA, R.- ABELIOVICH, A. Remodeling neurodegeneration: Somatic cell reprogramming-based models of adult neurological disorders. In NEURON. ISSN 0896-6273, 2013, vol. 78, no.6, p.957-969. SARACENO, C.- MUSARDO, S.- MARCELLO, E.- PELUCCHI, S.- DI LUCA, M. Modeling alzheimer's disease: From past to future. In FRONTIERS IN PHARMACOLOGY. ISSN 1663-9812 , 2013, art. no. Article 77 . CHIRILA, F. V.- KHAN, T. K.- ALKON, D. L. Spatiotemporal complexity of fibroblast networks screens for alzheimer's disease. In JOURNAL OF ALZHEIMER'S DISEASE. ISSN 1387-2877, 2013,vol.33, no.1, p.165-176. FONG, H.- WANG, C.- KNOFERLE, J.- WALKER, D.- BALESTRA, M. E.- TONG, L. M.- HUANG, Y. Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells. In STEM CELL REPORTS, ISSN 22136711, 2013, vol.3,p. 226-234. FROESTL, W.- PFEIFER, A.- MUHS, A. Cognitive enhancers (nootropics). part 3: Drugs interacting with targets other than receptors or enzymes. disease-modifying drugs. In JOURNAL OF ALZHEIMER'S DISEASE. ISSN 1387-2877, 2013, vol. 34, no.1,p. 1-114. EGASHIRA, T.- YUASA, S.- FUKUDA, K. Novel insights into disease modeling using induced pluripotent stem cells. In BIOLOGICAL AND PHARMACEUTICAL BULLETIN. ISSN 0918-6158, 2013,vol.36, no.2, p. 182-188. AMMAR, M.- SMADJA, C.- GIANG THI PHUONG, L.- AZZOUZ, M.- VIGNERON, J.- ETCHEBERRY, A.- DUFOUR-GERGAM, E. A new controlled concept of immune-sensing platform for specific detection of alzheimer's biomarkers. In BIOSENSORS AND BIOELECTRONICS. ISSN 0956-5663, 2013, vol.40, no.1, p. 329-335. VAZIN, T.- BALL, K. A.- LU, H.- PARK, H.- ATAEIJANNATI, Y.- HEAD-GORDON, T.- SCHAFFER, D. V. Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: A model system to study neurotoxicity in alzheimer's disease. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, 2014, vol.62, p.62-72. BRACK, Andrew S. - HOCHEDLINGER, Konrad. ISSCR 2013: Back to Bean Town. In STEM CELL REPORTS. ISSN 2213-6711, DEC 17 2013, vol. 1, no. 6, p. 479-485. MERTENS, Jerome - STUEBER, Kathrin - WUNDERLICH, Patrick - LADEWIG, Julia - KESAVAN, Jaideep C. - VANDENBERGHE, Rik - VANDENBULCKE, Mathieu - VAN DAMME, Philip - WALTER, Jochen - BRUESTLE, Oliver - KOCH, Philipp. APP Processing in Human Pluripotent Stem Cell-Derived Neurons Is Resistant to NSAID-Based gamma-Secretase Modulation. In STEM CELL REPORTS. ISSN 2213-6711, DEC 17 2013, vol. 1, no. 6, p. 491-498. BRENNAND, Kristen J. Inducing Cellular Aging: Enabling Neurodegeneration-in-a-Dish. In CELL STEM CELL. ISSN 1934-5909, DEC 5 2013, vol. 13, no. 6, p. 635-636. PHANTHONG, Phetcharat - RAVEH-AMIT, Hadas - LI, Tong - KITIYANANT, Yindee - DINNYES, Andras. Is aging a barrier to reprogramming? Lessons from induced pluripotent stem cells. In BIOGERONTOLOGY. ISSN 1389-5729, DEC 2013, vol. 14, no. 6, SI, p. 591-602. FAIZ, Maryam - NAGY, Andras. Induced Pluripotent Stem Cells and Disorders of the Nervous System: Progress, Problems, and Prospects. In NEUROSCIENTIST. ISSN 1073-8584, DEC 2013, vol. 19, no. 6, p. 567-577. TANDON, Nina - MAROLT, Darja - CIMETTA, Elisa - VUNJAK-NOVAKOVIC, Gordana. Bioreactor engineering of stem cell environments. In BIOTECHNOLOGY ADVANCES. ISSN 0734-9750, NOV 15 2013, vol. 31, no. 7, SI, p. 1020-1031. WANG, Tao - WARREN, Stephen T. - JIN, Peng. Toward pluripotency by reprogramming: mechanisms and application. In PROTEIN & CELL. ISSN 1674-800X, NOV 2013, vol. 4, no. 11, p. 820-832. JIAO, Jiao - YANG, Yuanyuan - SHI, Yiwu - CHEN, Jiayu - GAO, Rui - FAN, Yong - YAO, Hui - LIAO, Weiping - SUN, Xiao-Fang - GAO, Shaorong. Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, NOV 1 2013, vol. 22, no. 21, p. 4241-4252. GAGE, Fred H. - TEMPLE, Sally. Neural Stem Cells: Generating and Regenerating the Brain. In NEURON. ISSN 0896-6273, OCT 30 2013, vol. 80, no. 3, p. 588-601. VERPELLI, Chiara - CARLESSI, Luigi - BECHI, Giulia - POLI, Elena Fusar - ORELLANA, Daniel - HEISE, Christopher - FRANCESCHETTI, Silvana - MANTEGAZZA, Renato - MANTEGAZZA, Massimo - DELIA, Domenico - SALA, Carlo. Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells. In FRONTIERS IN CELLULAR NEUROSCIENCE. ISSN 1662-5102, OCT 24 2013, vol. 7. RUTTEN, Bart P. F. - STEINBUSCH, Harry W. M. Current concepts in Alzheimer's Disease: molecules, models and translational perspectives. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, OCT 22 2013, vol. 8. ZHANG, Zhijun - ALMEIDA, Sandra - LU, Yubing - NISHIMURA, Agnes L. - PENG, Lingtao - SUN, Danqiong - WU, Bei - KARYDAS, Anna M. - TARTAGLIA, Maria C. - FONG, Jamie C. - MILLER, Bruce L. - FARESE, Robert V., Jr. - MOORE, Melissa J. - SHAW, Christopher E. - GAO, Fen-Biao. Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations. In PLOS ONE. ISSN 1932-6203, OCT 15 2013, vol. 8, no. 10. WU, Menghua - CHEN, Guilai - HU, Baoyang. Induced Pluripotency for Translational Research. In Genomics Proteomics & Bioinformatics. ISSN 1672-0229, OCT 2013, vol. 11, no. 5, Sp. Iss. SI, p. 288-293. MCKERNAN, Ruth - WATT, Fiona M. What is the point of large-scale collections of human induced pluripotent stem cells?. In NATURE BIOTECHNOLOGY. ISSN 1087-0156, OCT 2013, vol. 31, no. 10, p. 875-877. FONG, Helen - WANG, Chengzhong - KNOFERLE, Johanna - WALKER, David - BALESTRA, Maureen E. - TONG, Leslie M. - LEUNG, Laura - RING, Karen L. - SEELEY, William W. - KARYDAS, Anna - KSHIRSAGAR, Mihir A. - BOXER, Adam L. - KOSIK, Kenneth S. - MILLER, Bruce L. - HUANG, Yadong. Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells. In STEM CELL REPORTS. ISSN 2213-6711, SEP 10 2013, vol. 1, no. 3, p. 226-234. TANG, Xin - ZHOU, Li - WAGNER, Alecia M. - MARCHETTO, Maria C. N. - MUOTRI, Alysson R. - GAGE, Fred H. - CHEN, Gong. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. In STEM CELL RESEARCH. ISSN 1873-5061, SEP 2013, vol. 11, no. 2, p. 743-757. MAHAIRAKI, V. - RYU, J. - PETERS, A. - CHANG, Q. - LI, T. - PARK, T.S. - BURRIDGE, P.W. - TALBOT, C.C. - ASNAGHI, L. - MARTIN, L.J. - ZAMBIDIS, E.T. - KOLIATSOS, V.E. Induced Pluripotent Stem Cells from Familial Alzheimer's Disease Patients Differentiate into Mature Neurons with Amyloidogenic Properties. In STEM CELLS AND DEVELOPMENT. ISSN 1547-3287, DEC 15 2014, vol. 23, no. 24, p. 2996-3010. LIAO, F. - HOLTZMAN, D.M. Human Neurons Derived From Induced Pluripotent Stem Cells as a New Platform for Preclinical Drug Screening and Development. In JAMA NEUROLOGY. ISSN 2168-6149, DEC 2014, vol. 71, no. 12, p. 1475-1476. LIU, Q. - WALTZ, S. - WOODRUFF, G. - OUYANG, J. - ISRAEL, M.A. - HERRERA, C. - SARSOZA, F. - TANZI, R.E. - KOO, E.H. - RINGMAN, J.M. - GOLDSTEIN, L.S.B. - WAGNER, S.L. - YUAN, S.H. Effect of Potent gamma-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1-Induced Pluripotent Stem Cell Mutant Carriers. In JAMA NEUROLOGY. ISSN 2168-6149, DEC 2014, vol. 71, no. 12, p. 1481-1489. KOPPENSTEINER, P. - BOEHM, S. - ARANCIO, O. Electrophysiological Profiles of Induced Neurons Converted Directly from Adult Human Fibroblasts Indicate Incomplete Neuronal Conversion. In CELLULAR REPROGRAMMING. ISSN 2152-4971, DEC 1 2014, vol. 16, no. 6, p. 439-446. STANCU, I.C. - VASCONCELOS, B. - TERWEL, D. - DEWACHTER, I. Models of beta-amyloid induced Tau-pathology: the long and "folded" road to understand the mechanism. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, NOV 18 2014, vol. 9. KIM, H.S. - BERNITZ, J.M. - LEE, D.F. - LEMISCHKA, I.R. Genomic Editing Tools to Model Human Diseases with Isogenic Pluripotent Stem Cells. In STEM CELLS AND DEVELOPMENT. ISSN 1547-3287, NOV 15 2014, vol. 23, no. 22, p. 2673-2686. TU, S.C. - OKAMOTO, S. - LIPTON, S.A. - XU, H.X. Oligomeric A beta-induced synaptic dysfunction in Alzheimer's disease. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, NOV 14 2014, vol. 9. CHOI, S.H. - KIM, Y.H. - HEBISCH, M. - SLIWINSKI, C. - LEE, S. - D'AVANZO, C. - CHEN, H.C. - HOOLI, B. - ASSELIN, C. - MUFFAT, J. - KLEE, J.B. - ZHANG, C. - WAINGER, B.J. - PEITZ, M. - KOVACS, D.M. - WOOLF, C.J. - WAGNER, S.L. - TANZI, R.E. - KIM, D.Y. A three-dimensional human neural cell culture model of Alzheimer's disease. In NATURE. ISSN 0028-0836, NOV 13 2014, vol. 515, no. 7526, p. 274-U293. GRIESHAMMER, U. - SHEPARD, K.A. Proceedings: Consideration of Genetics in the Design of Induced Pluripotent Stem Cell-Based Models of Complex Disease. In STEM CELLS TRANSLATIONAL MEDICINE. ISSN 2157-6564, NOV 2014, vol. 3, no. 11, p. 1253-1258. VELASCO, I. - SALAZAR, P. - GIORGETTI, A. - RAMOS-MEJA, V. - CASTANO, J. - ROMERO-MOYA, D. - MENENDEZ, P. Concise Review: Generation of Neurons From Somatic Cells of Healthy Individuals and Neurological Patients Through Induced Pluripotency or Direct Conversion. In STEM CELLS. ISSN 1066-5099, NOV 2014, vol. 32, no. 11, p. 2811-2817. HEILKER, R. - TRAUB, S. - REINHARDT, P. - SCHOLER, H.R. - STERNECKERT, J. iPS cell derived neuronal cells for drug discovery. In TRENDS IN PHARMACOLOGICAL SCIENCES. ISSN 0165-6147, OCT 2014, vol. 35, no. 10, p. 510-519. FERRAIUOLO, L. The non-cell-autonomous component of ALS: new in vitro models and future challenges. In BIOCHEMICAL SOCIETY TRANSACTIONS. ISSN 0300-5127, OCT 2014, vol. 42, 5, p. 1270-1274. SMALL, S.A. Isolating Pathogenic Mechanisms Embedded within the Hippocampal Circuit through Regional Vulnerability. In NEURON. ISSN 0896-6273, OCT 1 2014, vol. 84, no. 1, p. 32-39. ALI, F. - STOTT, S.R.W. - BARKER, R.A. Stem cells and the treatment of Parkinson's disease. In EXPERIMENTAL NEUROLOGY. ISSN 0014-4886, OCT 2014, vol. 260, SI, p. 3-11. YAMASHITA, A. - MORIOKA, M. - KISHI, H. - KIMURA, T. - YAHARA, Y. - OKADA, M. - FUJITA, K. - SAWAI, H. - IKEGAWA, S. - TSUMAKI, N. Statin treatment rescues FGFR3 skeletal dysplasia phenotypes. In NATURE. ISSN 0028-0836, SEP 25 2014, vol. 513, no. 7519, p. 507-+. ISOBE, K. - CHENG, Z. - NISHIO, N. - SUGANYA, T. - TANAKA, Y. - ITO, S. iPSCs, aging and age-related diseases. In NEW BIOTECHNOLOGY. ISSN 1871-6784, SEP 25 2014, vol. 31, no. 5, p. 411-421. LIVESEY, F.J. Human stem cell models of dementia. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, SEP 15 2014, vol. 23, 1, p. R35-R39. ROSS, C.A. - AKIMOV, S.S. Human-induced pluripotent stem cells: potential for neurodegenerative diseases. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, SEP 15 2014, vol. 23, 1, p. R17-R26. FAN, X.T. - SUN, D.Y. - TANG, X.T. - CAI, Y.L. - YIN, Z.Q. - XU, H.W. Stem-Cell Challenges in the Treatment of Alzheimer's Disease: A Long Way from Bench to Bedside. In MEDICINAL RESEARCH REVIEWS. ISSN 0198-6325, SEP 2014, vol. 34, no. 5, p. 957-978. WANG, C.C. - KUO, Y.C. Capillary electrophoresis of induced pluripotent stem cells during differentiation toward neurons. In JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS. ISSN 1876-1070, SEP 2014, vol. 45, no. 5, p. 2096-2105. CANET-AVILES, R. - LOMAX, G.P. - FEIGAL, E.G. - PRIEST, C. Proceedings: Cell Therapies for Parkinson's Disease From Discovery to Clinic. In STEM CELLS TRANSLATIONAL MEDICINE. ISSN 2157-6564, SEP 2014, vol. 3, no. 9, p. 979-991. STERNECKERT, J.L. - REINHARDT, P. - SCHOLER, H.R. Investigating human disease using stem cell models. In NATURE REVIEWS GENETICS. ISSN 1471-0056, SEP 2014, vol. 15, no. 9, p. 625-639. LANE-DONOVAN, C. - PHILIPS, G.T. - HERZ, J. More than Cholesterol Transporters: Lipoprotein Receptors in CNS Function and Neurodegeneration. In NEURON. ISSN 0896-6273, AUG 20 2014, vol. 83, no. 4, p. 771-787. LU, P. - WOODRUFF, G. - WANG, Y.Z. - GRAHAM, L. - HUNT, M. - WU, D. - BOEHLE, E. - AHMAD, R. - POPLAWSKI, G. - BROCK, J. - GOLDSTEIN, L.S.B. - TUSZYNSKI, M.H. Long-Distance Axonal Growth from Human Induced Pluripotent Stem Cells after Spinal Cord Injury. In NEURON. ISSN 0896-6273, AUG 20 2014, vol. 83, no. 4, p. 789-796. DE BOER, A.S. - KOSZKA, K. - KISKINIS, E. - SUZUKI, N. - DAVIS-DUSENBERY, B.N. - EGGAN, K. Genetic validation of a therapeutic target in a mouse model of ALS. In SCIENCE TRANSLATIONAL MEDICINE. ISSN 1946-6234, AUG 6 2014, vol. 6, no. 248. GARBER, K. Between disease and a dish. In NATURE BIOTECHNOLOGY. ISSN 1087-0156, AUG 2014, vol. 32, no. 8, p. 712-715. LANGLEY, G.R. Considering a new paradigm for Alzheimer's disease research. In DRUG DISCOVERY TODAY. ISSN 1359-6446, AUG 2014, vol. 19, no. 8, p. 1114-1124. WESSELING, H. - GUEST, P.C. - LAGO, S.G. - BAHN, S. Technological advances for deciphering the complexity of psychiatric disorders: merging proteomics with cell biology. In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. ISSN 1461-1457, AUG 2014, vol. 17, no. 8, p. 1327-1341. PRE, D. - NESTOR, M.W. - SPROUL, A.A. - JACOB, S. - KOPPENSTEINER, P. - CHINCHALONGPORN, V. - ZIMMER, M. - YAMAMOTO, A. - NOGGLE, S.A. - ARANCIO, O. A Time Course Analysis of the Electrophysiological Properties of Neurons Differentiated from Human Induced Pluripotent Stem Cells (iPSCs). In PLOS ONE. ISSN 1932-6203, JUL 29 2014, vol. 9, no. 7. BROCCOLI, V. - GIANNELLI, S.G. - MAZZARA, P.G. Modeling physiological and pathological human neurogenesis in the dish. In FRONTIERS IN NEUROSCIENCE. ISSN 1662-453X, JUL 24 2014, vol. 8. DE LAZARO, I. - YILMAZER, A. - KOSTARELOS, K. Induced pluripotent stem (iPS) cells: A new source for cell-based therapeutics?. In JOURNAL OF CONTROLLED RELEASE. ISSN 0168-3659, JUL 10 2014, vol. 185, p. 37-44. STEIN, J.L. - DE LA TORRE-UBIETA, L. - TIAN, Y. - PARIKSHAK, N.N. - HERNANDEZ, I.A. - MARCHETTO, M.C. - BAKER, D.K. - LU, D.N. - HINMAN, C.R. - LOWE, J.K. - WEXLER, E.M. - MUOTRI, A.R. - GAGE, F.H. - KOSIK, K.S. - GESCHWIND, D.H. A Quantitative Framework to Evaluate Modeling of Cortical Development by Neural Stem Cells. In NEURON. ISSN 0896-6273, JUL 2 2014, vol. 83, no. 1, p. 69-86. MURATORE, C.R. - RICE, H.C. - SRIKANTH, P. - CALLAHAN, D.G. - SHIN, T. - BENJAMIN, L.N.P. - WALSH, D.M. - SELKOE, D.J. - YOUNG-PEARSE, T.L. The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, JUL 2014, vol. 23, no. 13, p. 3523-3536. JALALI, M. - KIRKPATRICK, W.N.A. - CAMERON, M.G. - PAUKLIN, S. - VALLIER, L. Human Stem Cells for Craniomaxillofacial Reconstruction. In STEM CELLS AND DEVELOPMENT. ISSN 1547-3287, JUL 1 2014, vol. 23, no. 13, p. 1437-1451. FITZSIMONS, C.P. - VAN BODEGRAVEN, E. - SCHOUTEN, M. - LARDENOIJE, R. - KOMPOTIS, K. - KENIS, G. - VAN DEN HURK, M. - BOKS, M.P. - BIOJONE, C. - JOCA, S. - STEINBUSCH, H.W.M. - LUNNON, K. - MASTROENI, D.F. - MILL, J. - LUCASSEN, P.J. - COLEMAN, P.D. - VAN DEN HOVE, D.L.A. - RUTTEN, B.P.F. Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, JUN 25 2014, vol. 9. QIANG, L. - INOUE, K. - ABELIOVICH, A. Instant Neurons: Directed Somatic Cell Reprogramming Models of Central Nervous System Disorders. In BIOLOGICAL PSYCHIATRY. ISSN 0006-3223, JUN 15 2014, vol. 75, no. 12, p. 945-951. CHEN, H. - QIAN, K. - DU, Z.W. - CAO, J.Y. - PETERSEN, A. - LIU, H.S. - BLACKBOURN, L.W. - HUANG, C.L. - ERRIGO, A. - YIN, Y.N. - LU, J.F. - AYALA, M. - ZHANG, S.C. Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons. In CELL STEM CELL. ISSN 1934-5909, JUN 5 2014, vol. 14, no. 6, p. 796-809. SCHONDORF, D.C. - AURELI, M. - MCALLISTER, F.E. - HINDLEY, C.J. - MAYER, F. - SCHMID, B. - SARDI, S.P. - VALSECCHI, M. - HOFFMANN, S. - SCHWARZ, L.K. - HEDRICH, U. - BERG, D. - SHIHABUDDIN, L.S. - HU, J. - PRUSZAK, J. - GYGI, S.P. - SONNINO, S. - GASSER, T. - DELEIDI, M. iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis. In NATURE COMMUNICATIONS. ISSN 2041-1723, JUN 2014, vol. 5. VAN DEN AMEELE, J. - TIBERI, L. - VANDERHAEGHEN, P. - ESPUNY-CAMACHO, I. Thinking out of the dish: what to learn about cortical development using pluripotent stem cells. In TRENDS IN NEUROSCIENCES. ISSN 0166-2236, JUN 2014, vol. 37, no. 6, p. 334-342. HSU, Y.C. - CHEN, S.L. - WANG, Y.J. - CHEN, Y.H. - WANG, D.Y. - CHEN, L.Y. - CHEN, C.H. - CHEN, H.H. - CHIU, I.M. Signaling Adaptor Protein SH2B1 Enhances Neurite Outgrowth and Accelerates the Maturation of Human Induced Neurons. In STEM CELLS TRANSLATIONAL MEDICINE. ISSN 2157-6564, JUN 2014, vol. 3, no. 6, p. 713-722. IMAIZUMI, Y. - OKANO, H. Modeling human neurological disorders with induced pluripotent stem cells. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, MAY 2014, vol. 129, no. 3, p. 388-399. ESCH, M.B. - SMITH, A.S.T. - PROT, J.M. - OLEAGA, C. - HICKMAN, J.J. - SHULER, M.L. How multi-organ microdevices can help foster drug development. In ADVANCED DRUG DELIVERY REVIEWS. ISSN 0169-409X, APR 20 2014, vol. 69, p. 158-169. HUNTER, S. - BRAYNE, C. Integrating the molecular and the population approaches to dementia research to help guide the future development of appropriate therapeutics. In BIOCHEMICAL PHARMACOLOGY. ISSN 0006-2952, APR 15 2014, vol. 88, no. 4, SI, p. 652-660. KEVERNE, E.B. SIGNIFICANCE OF EPIGENETICS FOR UNDERSTANDING BRAIN DEVELOPMENT, BRAIN EVOLUTION AND BEHAVIOUR. In NEUROSCIENCE. ISSN 0306-4522, APR 4 2014, vol. 264, p. 207-217. DOEGE, C.A. - ABELIOVICH, A. Dementia in a Dish. In BIOLOGICAL PSYCHIATRY. ISSN 0006-3223, APR 1 2014, vol. 75, no. 7, p. 558-564. OKANO, H. - YAMANAKA, S. iPS cell technologies: significance and applications to CNS regeneration and disease. In MOLECULAR BRAIN. ISSN 1756-6606, MAR 31 2014, vol. 7. GHATE, P.S. - SIDHAR, H. - CARLSON, G.A. - GIRI, R.K. Development of a novel cellular model of Alzheimer's disease utilizing neurosphere cultures derived from B6C3-Tg(APPswe,PSEN1dE9)85Dbo/J embryonic mouse brain. In SPRINGERPLUS. ISSN 2193-1801, MAR 26 2014, vol. 3. LEE, W.C. - ALMEIDA, S. - PRUDENCIO, M. - CAULFIELD, T.R. - ZHANG, Y.J. - TAY, W.M. - BAUER, P.O. - CHEW, J. - SASAGURI, H. - JANSEN-WEST, K.R. - GENDRON, T.F. - STETLER, C.T. - FINCH, N. - MACKENZIE, I.R. - RADEMAKERS, R. - GAO, F.B. - PETRUCELLI, L. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, MAR 15 2014, vol. 23, no. 6, p. 1467-1478. INOUE, H. - NAGATA, N. - KUROKAWA, H. - YAMANAKA, S. iPS cells: a game changer for future medicine. In EMBO JOURNAL. ISSN 0261-4189, MAR 3 2014, vol. 33, no. 5, p. 409-417. CHEN, H.M. - DELONG, C.J. - BAME, M. - RAJAPAKSE, I. - HERRON, T.J. - MCINNIS, M.G. - O'SHEA, K.S. Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients. In TRANSLATIONAL PSYCHIATRY. ISSN 2158-3188, MAR 2014, vol. 4. SRIKANTH, P. - YOUNG-PEARSE, T.L. Stem Cells on the Brain: Modeling Neurodevelopmental and Neurodegenerative Diseases Using Human Induced Pluripotent Stem Cells. In JOURNAL OF NEUROGENETICS. ISSN 0167-7063, MAR-JUN 2014, vol. 28, no. 1-2, p. 5-29. RUGGIERI, M. - RIBOLDI, G. - BRAJKOVIC, S. - BUCCHIA, M. - BRESOLIN, N. - COMI, G.P. - CORTI, S. Induced neural stem cells: Methods of reprogramming and potential therapeutic applications. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, MAR 2014, vol. 114, p. 15-24. JANG, S.F. - LIU, W.H. - SONG, W.S. - CHIANG, K.L. - MA, H.I. - KAO, C.L. - CHEN, M.T. Nanomedicine-Based Neuroprotective Strategies in Patient Specific-iPSC and Personalized Medicine. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, MAR 2014, vol. 15, no. 3, p. 3904-3925. MIRZA, Z. - PILLAI, V.G. - ZHONG, W.Z. Structure of N-Terminal Sequence Asp-Ala-Glu-Phe-Arg-His-Asp- Ser of A beta-Peptide with Phospholipase A(2) from Venom of Andaman Cobra Sub-Species Naja naja sagittifera at 2.0 angstrom Resolution. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, MAR 2014, vol. 15, no. 3, p. 4221-4236. VAN DER KANT, R. - NEEFJES, J. Small regulators, major consequences - Ca2+ and cholesterol at the endosome-ER interface. In JOURNAL OF CELL SCIENCE. ISSN 0021-9533, MAR 1 2014, vol. 127, no. 5, p. 929-938. SALIMI, A. - NADRI, S. - GHOLLASI, M. - KHAJEH, K. - SOLEIMANI, M. Comparison of different protocols for neural differentiation of human induced pluripotent stem cells. In MOLECULAR BIOLOGY REPORTS. ISSN 0301-4851, MAR 2014, vol. 41, no. 3, p. 1713-1721. AIGNER, S. - HECKEL, T. - ZHANG, J.T.D. - ANDREAE, L.C. - JAGASIA, R. Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish. In PSYCHOPHARMACOLOGY. ISSN 0033-3158, MAR 2014, vol. 231, no. 6, p. 1089-1104. ALMENAR-QUERALT, A. - FALZONE, T.L. - SHEN, Z.X. - LILLO, C. - KILLIAN, R.L. - ARREOLA, A.S. - NIEDERST, E.D. - NG, K.S. - KIM, S.N. - BRIGGS, S.P. - WILLIAMS, D.S. - GOLDSTEIN, L.S.B. UV Irradiation Accelerates Amyloid Precursor Protein (APP) Processing and Disrupts APP Axonal Transport. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, FEB 26 2014, vol. 34, no. 9, p. 3320-3339. NEEFJES, J. - VAN DER KANT, R. Stuck in traffic: an emerging theme in diseases of the nervous system. In TRENDS IN NEUROSCIENCES. ISSN 0166-2236, FEB 2014, vol. 37, no. 2, p. 66-76. HIBAOUI, Y. - GRAD, I. - LETOURNEAU, A. - SAILANI, M.R. - DAHOUN, S. - SANTONI, F.A. - GIMELLI, S. - GUIPPONI, M. - PELTE, M.F. - BENA, F. - ANTONARAKIS, S.E. - FEKI, A. Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21. In EMBO MOLECULAR MEDICINE. ISSN 1757-4676, FEB 2014, vol. 6, no. 2, p. 259-277. WANG, W. - MUTKA, A.L. - ZMRZLJAK, U.P. - ROZMAN, D. - TANILA, H. - GYLLING, H. - REMES, A.M. - HUTTUNEN, H.J. - IKONEN, E. Amyloid precursor protein alpha- and beta-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2. In FASEB JOURNAL. ISSN 0892-6638, FEB 2014, vol. 28, no. 2, p. 849-860. VAZIN, T. - BALL, K.A. - LU, H. - PARK, H. - ATAEIJANNATI, Y. - HEAD-GORDON, T. - POO, M.M. - SCHAFFER, D.V. Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: A model system to study neurotoxicity in Alzheimer's disease. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, FEB 2014, vol. 62, p. 62-72. ZHANG, D.W. - PEKKANEN-MATTILA, M. - SHAHSAVANI, M.O. - FALK, A. - TEIXEIRA, A.I. - HERLAND, A. A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons. In BIOMATERIALS. ISSN 0142-9612, FEB 2014, vol. 35, no. 5, p. 1420-1428. HARGUS, G. - EHRLICH, M. - HALLMANN, A.L. - KUHLMANN, T. Human stem cell models of neurodegeneration: a novel approach to study mechanisms of disease development. In ACTA NEUROPATHOLOGICA. ISSN 0001-6322, FEB 2014, vol. 127, no. 2, p. 151-173. ROMANO, G. - MORALES, F. - MARINO, I.R. - GIORDANO, A. A Commentary on iPS Cells: Potential Applications in Autologous Transplantation, Study of Illnesses and Drug Screening. In JOURNAL OF CELLULAR PHYSIOLOGY. ISSN 0021-9541, FEB 2014, vol. 229, no. 2, p. 148-152. DUAN, L.S. - BHATTACHARYYA, B.J. - BELMADANI, A. - PAN, L.L. - MILLER, R.J. - KESSLER, J.A. Stem cell derived basal forebrain cholinergic neurons from Alzheimer's disease patients are more susceptible to cell death. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, JAN 8 2014, vol. 9. SPROUL, A.A. - JACOB, S. - PRE, D. - KIM, S.H. - NESTOR, M.W. - NAVARRO-SOBRINO, M. - SANTA-MARIA, I. - ZIMMER, M. - AUBRY, S. - STEELE, J.W. - KAHLER, D.J. - DRANOVSKY, A. - ARANCIO, O. - CRARY, J.F. - GANDY, S. - NOGGLE, S.A. Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors. In PLOS ONE. ISSN 1932-6203, JAN 8 2014, vol. 9, no. 1. FOSSATI, V. - DOUVARAS, P. Generating induced pluripotent stem cells for multiple sclerosis therapy. In REGENERATIVE MEDICINE. ISSN 1746-0751, 2014, vol. 9, no. 6, p. 709-711. GAO, K. - NIU, M.Y. - ZHAI, X. - HUANG, Y.L. - TIAN, X. - LI, T.G. GENETIC AND NON-GENETIC FACTORS RESPONSIBLE FOR MITOCHONDRIAL FAILURE AND ALZHEIMER'S DISEASE. In GENETIKA-BELGRADE. ISSN 0534-0012, 2014, vol. 46, no. 2, p. 631-647. ALCOLEA, D. - CARMONA-IRAGUI, M. - SUAREZ-CALVET, M. - SANCHEZ-SAUDINOS, M.B. - SALA, I. - ANTON-AGUIRRE, S. - BLESA, R. - CLARIMON, J. - FORTEA, J. - LLEO, A. Relationship Between beta-Secretase, Inflammation and Core Cerebrospinal Fluid Biomarkers for Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2014, vol. 42, no. 1, p. 157-167. BALDASSARRO, V.A. - CALZA, L. - FERNANDEZ, M. - GIARDINO, L. - GIULIANI, A. - LORENZINI, L. - MANGANO, C. - SIVILIA, S. Alzheimer's Disease: Discussing the "Bench-to-Bed" and the "Bed-to-Bench" Pathway Linking Preclinical and Clinical Research. In LOST IN TRANSLATION: BARRIERS TO INCENTIVES FOR TRANSLATIONAL RESEARCH IN MEDICAL SCIENCES. 2014, p. 409-441. FELDMAN, H.H. - HAAS, M. - GANDY, S. - SCHOEPP, D.D. - CROSS, A.J. - MAYEUX, R. - SPERLING, R.A. - FILLIT, H. - VAN DE HOEF, D.L. - DOUGAL, S. - NYE, J.S. Alzheimer's disease research and development: a call for a new research roadmap. In ANNALS REPORTS. ISSN 0077-8923, 2014, vol. 1313, p. 1-16. ESEALONA, J.A.G. - MORATALLA, N.L. Pluripotent stem cells on cell therapy. In ANALES DEL SISTEMA SANITARIO DE NAVARRA. ISSN 1137-6627, JAN-APR 2014, vol. 37, no. 1, p. 129-136. FU, X.M. - RONG, Z.L. - ZHU, S.Y. - WANG, X.C. - XU, Y. - LAKE, B.B. Genetic approach to track neural cell fate decisions using human embryonic stem cells. In PROTEIN & CELL. ISSN 1674-800X, JAN 2014, vol. 5, no. 1, p. 69-79. JACOBS, B.M. Stemming the Hype: What Can We Learn from iPSC Models of Parkinson's Disease and How Can We Learn It?. In JOURNAL OF PARKINSONS DISEASE. ISSN 1877-7171, 2014, vol. 4, no. 1, p. 15-27. ZANELLA, F. - LYON, R.C. - SHEIKH, F. Modeling heart disease in a dish: From somatic cells to disease-relevant cardiomyocytes. In TRENDS IN CARDIOVASCULAR MEDICINE. ISSN 1050-1738, JAN 2014, vol. 24, no. 1, p. 32-44. ZHANG, M.H. - LUO, G.R. - ZHOU, Y.J. - WANG, S.H. - ZHONG, Z. Phenotypic Screens Targeting Neurodegenerative Diseases. In JOURNAL OF BIOMOLECULAR SCREENING. ISSN 1087-0571, JAN 2014, vol. 19, no. 1, SI, p. 1-16. AMMAR, M.- SMADJA, C.- PHUONG LY, G. T.- TANDJIGORA, D.- VIGNERON, J.- ETCHEBERRY, A.- DUFOUR-GERGAM, E. Chemical engineering of self-assembled alzheimers peptide on a silanized silicon surface. In LANGMUIR, ISSN 0743-7463, 2014, vol. 30, no.20, p. 5863-5872. CHOI, S. H.- KIM, Y. H.- HEBISCH, M.- SLIWINSKI, C.- LEE, S., D'AVANZO, C.- KIM, D. Y. A three-dimensional human neural cell culture model of alzheimer's disease. In NATURE, ISSN 0028-0836, 2014, vol.515, no.7526, p.274-278 FELDMAN, H. H.- HAAS, M.- GANDY, S.- SCHOEPP, D. D.- CROSS, A. J.- MAYEUX, R.- NYE, J. S. Alzheimer's disease research and development: A call for a new research roadmap In ANNALS OF THE NEW YORK ACADEMY OF SCIENCES ISSN 0077-8923, 2014, vol. 1313, no.1, p. 1-16 GÁMEZ ESCALONA, J. A.- LÓPEZ MORATALLA, N. Pluripotent stem cells on cell therapy. [Las células troncales pluripotenciales en la terapia celular] In ANALES DEL SISTEMA SANITARIO DE NAVARRA, ISSN 1137-6627, 2014, vol. 37, no.1, p.129-136. GRIESHAMMER, U.- SHEPARD, K. A. Proceedings: Consideration of genetics in the design of induced pluripotent stem cell-based models of complex disease. In STEM CELLS TRANSLATIONAL MEDICINE, ISSN 2157-6564, 2014, vol.3, no.11, p.1253-1259. HAN, G.- SUN, J.- WANG, J.- BAI, Z.- SONG, F.- LEI, H. Genomics in neurological disorders. In GENOMICS, PROTEOMICS AND BIOINFORMATICS, ISSN 1672-0229, 2014,vol. 12, no.4, p.156-163. HEILKER, R.- TRAUB, S.- REINHARDT, P.- SCHÖLER, H. R.- STERNECKERT, J. (2014). IPS cell derived neuronal cells for drug discovery. In TRENDS IN PHARMACOLOGICAL SCIENCES, ISSN 0165-6147, 2014, vol.35, no.10, p.510-519. KIM, H. S.- BERNITZ, J. M.- LEE, D. - LEMISCHKA, I. R. Genomic editing tools to model human diseases with isogenic pluripotent stem cells. In STEM CELLS AND DEVELOPMENT, ISSN 1547-3287, 2014, vol. 23, no.22, p.2673-2686. KOPPENSTEINER, P.- BOEHM, S.- ARANCIO, O. Electrophysiological profiles of induced neurons converted directly from adult human fibroblasts indicate incomplete neuronal conversion. In CELLULAR REPROGRAMMING, ISSN 2152-4971, vol. 16, no.6, p.439-446. LIAO, F.- HOLTZMAN, D. M. Human neurons derived from induced pluripotent stem cells as a new platform for preclinical drug screening and development. In JAMA NEUROLOGY,ISSN 2168-6149, 2014, vol. 71, no.12, p.1475-1476. LIU, J.- ZHANG, Z.- XUE, J.- ZHANG, H.- LIU, Y.- HU, F. A hypothesis for regenerative therapy for neuronal disease: Stem cells within artificial niche. In CURRENT SIGNAL TRANSDUCTION THERAPY, ISSN 1574-3624, 2014 vol.9, no.1, p.38-43. LIU, Q.- WALTZ, S.- WOODRUFF, G.- OUYANG, J.- ISRAEL, M. A.- HERRERA, C.- YUAN, S. H. Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers. In JAMA NEUROLOGY,ISSN 2168-6149, 2014, vol. 71, no.12, p.1481-1489. MA, Y. - DU, G. Development on neurodegenerative disorder modeling with induced pluripotent stem cells. In CHINESE PHARMACOLOGICAL BULLETIN,ISSN 1001-1978, 2014, vol. 30, no.9, p.1185-1189. STERNECKERT, J. L. REINHARDT, P.- SCHÖLER, H. R. Investigating human disease using stem cell models. In NATURE REVIEWS GENETICS, ISSN 1471-0056, 2014, vol. 15, no.9, p.625-639. TU, X. Effect of induced pluripotent stem cells in neurodegenerative diseases. In CHINESE JOURNAL OF CONTEMPORARY NEUROLOGY AND NEUROSURGERY, ISSN 1672-6731, 2014, vol.14, no.4, p.353-357. WANG, W.- LI, M.- WEI, Z.- WANG, Z.- BU, X.- LAI, W.- HU, Z. Bimodal imprint chips for peptide screening: Integration of high-throughput sequencing by MS and affinity analyses by surface plasmon resonance imaging. In ANALYTICAL CHEMISTRY, ISSN 0003-2700, 2014, vol.86, no.8, p.3703-3707. XIE, Y. Z.- ZHANG, R. X. Neurodegenerative diseases in a dish: The promise of iPSC technology in disease modeling and therapeutic discovery. In NEUROLOGICAL SCIENCES, ISSN 1590-1874, 2014, vol.36, no.1, p.21-27. PILECKA, I.- MIACZYNSKA, M. Efficient enhancement of signaling capacity: Signaling endosomes In VESICLE TRAFFICKING IN CANCER, Springer New York, ISBN 978-146146528-7, 2014, p.1-393 WADMAN, M. THE TRUTH ABOUT FETAL TISSUE RESEARCH. In NATURE. ISSN 0028-0836, DEC 10 2015, vol. 528, no. 7581, p. 178-181. IMAIZUMI, K. - SONE, T. - IBATA, K. - FUJIMORI, K. - YUZAKI, M. - AKAMATSU, W. - OKANO, H. Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. In STEM CELL REPORTS. ISSN 2213-6711, DEC 8 2015, vol. 5, no. 6, p. 1010-1022. MERTENS, J. - PAQUOLA, A.C.M. - KU, M.C. - HATCH, E. - BOHNKE, L. - LADJEVARDI, S. - MCGRATH, S. - CAMPBELL, B. - LEE, H. - HERDY, J.R. - GONCALVES, J.T. - TODA, T. - KIM, Y. - WINKLER, J. - YAO, J. - HETZER, M.W. - GAGE, F.H. Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. In CELL STEM CELL. ISSN 1934-5909, DEC 3 2015, vol. 17, no. 6, p. 705-718. SEAH, Y.F.S. - EL FARRAN, C.A. - WARRIER, T. - XU, J. - LOH, Y.H. Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, DEC 2015, vol. 16, no. 12, p. 28614-28634. NIZETIC, D. - CHEN, C.L. - HONG, W.J. - KOO, E.H. Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzhemer's Dementia in Down Syndrome: Multi-Faceted Roles of APP. In FRONTIERS IN BEHAVIORAL NEUROSCIENCE. ISSN 1662-5153, DEC 1 2015, vol. 9. WENKER, S.D. - CASALIA, M. - CANDEDO, V.C. - CASABONA, J.C. - PITOSSI, F.J. Cell reprogramming and neuronal differentiation applied to neurodegenerative diseases: Focus on Parkinson's disease. In FEBS LETTERS. ISSN 0014-5793, NOV 14 2015, vol. 589, no. 22, SI, p. 3396-3406. PALM, T. - BOLOGNIN, S. - MEISER, J. - NICKELS, S. - TRAGER, C. - MEILENBROCK, R.L. - BROCKHAUS, J. - SCHREITMULLER, M. - MISSLER, M. - SCHWAMBORN, J.C. Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. In SCIENTIFIC REPORTS. ISSN 2045-2322, NOV 6 2015, vol. 5. BEGUM, A.N. - GUOYNES, C. - CHO, J. - HAO, J.J. - LUTFY, K. - HONG, Y.L. Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres. In STEM CELL RESEARCH. ISSN 1873-5061, NOV 2015, vol. 15, no. 3, p. 731-741. LO CICERO, A. - NISSAN, X. Pluripotent stem cells to model Hutchinson-Gilford progeria syndrome (HGPS): Current trends and future perspectives for drug discovery. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, NOV 2015, vol. 24, B, p. 343-348. AMEMORI, T. - JENDELOVA, P. - RUZICKA, J. - URDZIKOVA, L.M. - SYKOVA, E. Alzheimer's Disease: Mechanism and Approach to Cell Therapy. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, NOV 2015, vol. 16, no. 11, p. 26417-26451. DENG, J. - HABIB, A. - OBREGON, D.F. - BARGER, S.W. - GIUNTA, B. - WANG, Y.J. - HOU, H.Y. - SAWMILLER, D. - TAN, J. Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3 signaling pathway. In JOURNAL OF NEUROCHEMISTRY. ISSN 0022-3042, NOV 2015, vol. 135, no. 3, p. 630-637. TANABE, K. - HAAG, D. - WERNIG, M. Direct somatic lineage conversion. In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. ISSN 0962-8436, OCT 19 2015, vol. 370, no. 1680. WILLEM, M. - TAHIROVIC, S. - BUSCHE, M.A. - OVSEPIAN, S.V. - CHAFAI, M. - KOOTAR, S. - HORNBURG, D. - EVANS, L.D.B. - MOORE, S. - DARIA, A. - HAMPEL, H. - MULLER, V. - GIUDICI, C. - NUSCHER, B. - WENNINGER-WEINZIERL, A. - KREMMER, E. - HENEKA, M.T. - THAL, D.R. - GIEDRAITIS, V. - LANNFELT, L. - MULLER, U. - LIVESEY, F.J. - MEISSNER, F. - HERMS, J. - KONNERTH, A. - MARIE, H. - HAASS, C. eta-Secretase processing of APP inhibits neuronal activity in the hippocampus. In NATURE. ISSN 0028-0836, OCT 15 2015, vol. 526, no. 7573, p. 443-+. D'AVANZO, C. - ARONSON, J. - KIM, Y.H. - CHOI, S.H. - TANZI, R.E. - KIM, D.Y. Alzheimer's in 3D culture: Challenges and perspectives. In BIOESSAYS. ISSN 0265-9247, OCT 2015, vol. 37, no. 10, p. 1139-1148. KIMBREL, E.A. - LANZA, R. Current status of pluripotent stem cells: moving the first therapies to the clinic. In NATURE REVIEWS DRUG DISCOVERY. ISSN 1474-1776, OCT 2015, vol. 14, no. 10, p. 681-692. LI, M. - PEHAR, M. - LIU, Y. - BHATTACHARYYA, A. - ZHANG, S.C. - O'RIORDAN, K.J. - BURGER, C. - D'ADAMIO, L. - PUGLIELLI, L. The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, OCT 2015, vol. 36, no. 10, p. 2725-2736. KIRWAN, P. - TURNER-BRIDGER, B. - PETER, M. - MOMOH, A. - ARAMBEPOLA, D. - ROBINSON, H.P.C. - LIVESEY, F.J. Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro. In DEVELOPMENT. ISSN 0950-1991, SEP 15 2015, vol. 142, no. 18, p. 3178-U152. XIAO, Q.L. - YAN, P. - MA, X.C. - LIU, H.Y. - PEREZ, R. - ZHU, A. - GONZALES, E. - TRIPOLI, D.L. - CZERNIEWSKI, L. - BALLABIO, A. - CIRRITO, J.R. - DIWAN, A. - LEE, J.M. Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing A beta Generation and Amyloid Plaque Pathogenesis. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, SEP 2 2015, vol. 35, no. 35, p. 12137-12151. LIU, W.N. - WANG, H.M. - WANG, Y.K. - LI, H.P. - JI, L. Metabolic factors-triggered inflammatory response drives anti-depressant effects of exercise in CUMS rats. In PSYCHIATRY RESEARCH. ISSN 0165-1781, AUG 30 2015, vol. 228, no. 3, p. 257-264. MENEGHELLO, G. - VERHEYEN, A. - VAN INGEN, M. - KUIJLAARS, J. - TUEFFERD, M. - VAN DEN WYNGAERT, I. - NUYDENS, R. EVALUATION OF ESTABLISHED HUMAN IPSC-DERIVED NEURONS TO MODEL NEURODEGENERATIVE DISEASES. In NEUROSCIENCE. ISSN 0306-4522, AUG 20 2015, vol. 301, p. 204-212. HUNSBERGER, J.G. - EFTHYMIOU, A.G. - MALIK, N. - BEHL, M. - MEAD, I.L. - ZENG, X.M. - SIMEONOV, A. - RAO, M. Induced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous System. In STEM CELLS AND DEVELOPMENT. ISSN 1547-3287, AUG 15 2015, vol. 24, no. 16, p. 1852-1864. SHUM, C. - MACEDO, S.C. - WARRE-CORNISH, K. - COCKS, G. - PRICE, J. - SRIVASTAVA, D.P. Utilizing induced pluripotent stem cells (iPSCs) to understand the actions of estrogens in human neurons. In HORMONES AND BEHAVIOR. ISSN 0018-506X, AUG 2015, vol. 74, SI, p. 228-242. YANG, D.J. - ZHU, L. - REN, J. - MA, R.J. - ZHU, H.W. - XU, J. Dysfunction of autophagy as the pathological mechanism of motor neuron disease based on a patient-specific disease. In NEUROSCIENCE BULLETIN. ISSN 1673-7067, AUG 2015, vol. 31, no. 4, SI, p. 445-451. LARDENOIJE, R. - IATROU, A. - KENIS, G. - KOMPOTIS, K. - STEINBUSCH, H.W.M. - MASTROENI, D. - COLEMAN, P. - LEMERE, C.A. - HOF, P.R. - VAN DEN HOVE, D.L.A. - RUTTEN, B.P.F. The epigenetics of aging and neurodegeneration. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, AUG 2015, vol. 131, p. 21-64. AKBARI, M. - MOREVATI, M. - CROTEAU, D. - BOHR, V.A. The role of DNA base excision repair in brain homeostasis and disease. In DNA REPAIR. ISSN 1568-7864, AUG 2015, vol. 32, SI, p. 172-179. WATSON, L.M. - WONG, M.M.K. - BECKER, E.B.E. Induced pluripotent stem cell technology for modelling and therapy of cerebellar ataxia. In OPEN BIOLOGY. ISSN 2046-2441, JUL 2015, vol. 5, no. 7. TREVISAN, M. - SINIGAGLIA, A. - DESOLE, G. - BERTO, A. - PACENTI, M. - PALU, G. - BARZON, L. Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems. In VIRUSES-BASEL. ISSN 1999-4915, JUL 2015, vol. 7, no. 7, p. 3835-3856. HUANG, C.Y. - CHU, H.L. - MUHEREMU, A. - ZUO, H.C. Neurorestorative strategies for Alzheimer's disease. In NEUROLOGY INDIA. ISSN 0028-3886, JUL-AUG 2015, vol. 63, no. 4, p. 583-588. SAYKIN, A.J. - SHEN, L. - YAO, X. - KIM, S. - NHO, K. - RISACHER, S.L. - RAMANAN, V.K. - FOROUD, T.M. - FABER, K.M. - SARWAR, N. - MUNSIE, L.M. - HU, X. - SOARES, H.D. - POTKIN, S.G. - THOMPSON, P.M. - KAUWE, J.S.K. - KADDURAH-DAOUK, R. - GREEN, R.C. - TOGA, A.W. - WEINER, M.W. Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans. In ALZHEIMERS & DEMENTIA. ISSN 1552-5260, JUL 2015, vol. 11, no. 7, p. 792-814. ACAB, A. - MUOTRI, A.R. The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment. In NEUROTHERAPEUTICS. ISSN 1933-7213, JUL 2015, vol. 12, no. 3, p. 534-545. KIM, Y.H. - CHOI, S.H. - D'AVANZO, C. - HEBISCH, M. - SLIWINSKI, C. - BYLYKBASHI, E. - WASHICOSKY, K.J. - KLEE, J.B. - BRUSTLE, O. - TANZI, R.E. - KIM, D.Y. A 3D human neural cell culture system for modeling Alzheimer's disease. In NATURE PROTOCOLS. ISSN 1754-2189, JUL 2015, vol. 10, no. 7, p. 985-1006. FU, C.H. - YAN, Z. - XU, H. - ZHANG, C. - ZHANG, Q. - WEI, A.H. - YANG, X. - WANG, Y. Isolation, identification and differentiation of human embryonic cartilage stem cells. In CELL BIOLOGY INTERNATIONAL. ISSN 1065-6995, JUL 2015, vol. 39, no. 7, p. 777-787. ROMERO, I.G. - PAVLOVIC, B.J. - HERNANDO-HERRAEZ, I. - ZHOU, X. - WARD, M.C. - BANOVICH, N.E. - KAGAN, C.L. - BURNETT, J.E. - HUANG, C.H. - MITRANO, A. - CHAVARRIA, C.I. - BEN-NUN, I.F. - LI, Y.C. - SABATINI, K. - LEONARDO, T.R. - PARAST, M. - MARQUES-BONET, T. - LAURENT, L.C. - LORING, J.F. - GILAD, Y. A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. In ELIFE. ISSN 2050-084X, JUN 23 2015, vol. 4. ICHIDA, J.K. - KISKINIS, E. Probing disorders of the nervous system using reprogramming approaches. In EMBO JOURNAL. ISSN 0261-4189, JUN 3 2015, vol. 34, no. 11, p. 1456-1477. SPROUL, A.A. Being human: The role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer's disease models. In MOLECULAR ASPECTS OF MEDICINE. ISSN 0098-2997, JUN-OCT 2015, vol. 43-44, SI, p. 54-65. BALOGH, Z. - RETHELYI, J. - MOLNAR, M. The role of induced pluripotent stem cells in neurological disease modeling. In ORVOSI HETILAP. ISSN 0030-6002, JUN 2015, vol. 156, no. 26, p. 1035-1039. BROCCOLI, V. - RUBIO, A. - TAVERNA, S. - YEKHLEF, L. Overcoming the hurdles for a reproducible generation of human functionally mature reprogrammed neurons. In EXPERIMENTAL BIOLOGY AND MEDICINE. ISSN 1535-3702, JUN 2015, vol. 240, no. 6, p. 787-794. CORTI, S. - FARAVELLI, I. - CARDANO, M. - CONTI, L. Human pluripotent stem cells as tools for neurodegenerative and neurodevelopmental disease modeling and drug discovery. In EXPERT OPINION ON DRUG DISCOVERY. ISSN 1746-0441, JUN 2015, vol. 10, no. 6, p. 615-629. MADISON, J.M. - ZHOU, F. - NIGAM, A. - HUSSAIN, A. - BARKER, D.D. - NEHME, R. - VAN DER VEN, K. - HSU, J. - WOLF, P. - FLEISHMAN, M. - O'DUSHLAINE, C. - ROSE, S. - CHAMBERT, K. - LAU, F.H. - AHFELDT, T. - RUECKERT, E.H. - SHERIDAN, S.D. - FASS, D.M. - NEMESH, J. - MULLEN, T.E. - DAHERON, L. - MCCARROLL, S. - SKLAR, P. - PERLIS, R.H. - HAGGARTY, S.J. Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, JUN 2015, vol. 20, no. 6, p. 703-717. NITYANANDAM, A. - BALDWIN, K.K. Advances in Reprogramming-Based Study of Neurologic Disorders. In STEM CELLS AND DEVELOPMENT. ISSN 1547-3287, JUN 1 2015, vol. 24, no. 11, p. 1265-1283. KIM, C. iPSC technology-Powerful hand for disease modeling and therapeutic screen. In BMB REPORTS. ISSN 1976-6696, MAY 31 2015, vol. 48, no. 5, p. 256-265. FERREIRA, S.T. - LOURENCO, M.V. - OLIVEIRA, M.M. - DE FELICE, F.G. Soluble amyloid-beta oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease. In FRONTIERS IN CELLULAR NEUROSCIENCE. ISSN 1662-5102, MAY 26 2015, vol. 9. BARDY, C. - VAN DEN HURK, M. - EAMES, T. - MARCHAND, C. - HERNANDEZ, R.V. - KELLOGG, M. - GORRIS, M. - GALET, B. - PALOMARES, V. - BROWN, J. - BANG, A.G. - MERTENS, J. - BOHNKE, L. - BOYER, L. - SIMON, S. - GAGE, F.H. Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro. In PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ISSN 0027-8424, MAY 19 2015, vol. 112, no. 20, p. E2725-E2734. MOORE, S. - EVANS, L.D.B. - ANDERSSON, T. - PORTELIUS, E. - SMITH, J. - DIAS, T.B. - SAURAT, N. - MCGLADE, A. - KIRWAN, P. - BLENNOW, K. - HARDY, J. - ZETTERBERG, H. - LIVESEY, F.J. APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex Neurons. In CELL REPORTS. ISSN 2211-1247, MAY 5 2015, vol. 11, no. 5, p. 689-696. LAI, S.Q. - ZHANG, M. - XU, D.S. - ZHANG, Y.Y. - QIU, L.S. - TIAN, C.H. - ZHENG, J.C. Direct reprogramming of induced neural progenitors: a new promising strategy for AD treatment. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, APR 18 2015, vol. 4. KIM, S.I. - OCEGUERA-YANEZ, F. - HIROHATA, R. - LINKER, S. - OKITA, K. - YAMADA, Y. - YAMAMOTO, T. - YAMANAKA, S. - WOLTJEN, K. KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency. In STEM CELL REPORTS. ISSN 2213-6711, APR 14 2015, vol. 4, no. 4, p. 727-743. FINKBEINER, S. - FRUMKIN, M. - KASSNER, P.D. Cell-Based Screening: Extracting Meaning from Complex Data. In NEURON. ISSN 0896-6273, APR 8 2015, vol. 86, no. 1, p. 160-174. YOUNG, J.E. - BOULANGER-WEILL, J. - WILLIAMS, D.A. - WOODRUFF, G. - BUEN, F. - REVILLA, A.C. - HERRERA, C. - ISRAEL, M.A. - YUAN, S.H. - EDLAND, S.D. - GOLDSTEIN, L.S.B. Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer's Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells. In CELL STEM CELL. ISSN 1934-5909, APR 2 2015, vol. 16, no. 4, p. 373-385. NIEWEG, K. - ANDREYEVA, A. - VAN STEGEN, B. - TANRIOVER, G. - GOTTMANN, K. Alzheimer's disease-related amyloid-beta induces synaptotoxicity in human iPS cell-derived neurons. In CELL DEATH & DISEASE. ISSN 2041-4889, APR 2015, vol. 6. BOGOMAZOVA, A.N. - VASSINA, E.M. - KISELEV, S.L. - LAGARKOVA, M.A. - LEBEDEVA, O.S. - NEKRASOV, E.D. - PANOVA, A.V. - PHILONENKO, E.S. - KHOMYAKOVA, E.A. - TSKHOVREBOVA, L.V. - CHESTKOV, I.V. - SHUTOVA, M.V. Genetic cell reprogramming: A new technology for basic research and applied usage. In RUSSIAN JOURNAL OF GENETICS. ISSN 1022-7954, APR 2015, vol. 51, no. 4, p. 386-396. REITZ, C. The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review. In MOLECULAR GENETICS AND GENOMICS. ISSN 1617-4615, APR 2015, vol. 290, no. 2, p. 413-427. CHANG, C.Y. - CHEN, S.M. - LU, H.E. - LAI, S.M. - LAI, P.S. - SHEN, P.W. - CHEN, P.Y. - SHEN, C.I. - HARN, H.J. - LIN, S.Z. - HWANG, S.M. - SU, H.L. N-butylidenephthalide Attenuates Alzheimer's Disease-Like Cytopathy in Down Syndrome Induced Pluripotent Stem Cell-Derived Neurons. In SCIENTIFIC REPORTS. ISSN 2045-2322, MAR 4 2015, vol. 5. BRANDL, B. - SCHNEIDER, S.A. - LORING, J.F. - HARDY, J. - GRIBBON, P. - MULLER, F.J. Stem Cell Reprogramming: Basic Implications and Future Perspective for Movement Disorders. In MOVEMENT DISORDERS. ISSN 0885-3185, MAR 2015, vol. 30, no. 3, p. 301-312. CROOK, J.M. - WALLACE, G. - TOMASKOVIC-CROOK, E. The potential of induced pluripotent stem cells in models of neurological disorders: implications on future therapy. In EXPERT REVIEW OF NEUROTHERAPEUTICS. ISSN 1473-7175, MAR 2015, vol. 15, no. 3, p. 295-304. ORACK, J.C. - DELEIDI, M. - PITT, D. - MAHAJAN, K. - NICHOLAS, J.A. - BOSTER, A.L. - RACKE, M.K. - COMABELLA, M. - WATANABE, F. - IMITOLA, J. Concise Review: Modeling Multiple Sclerosis With Stem Cell Biological Platforms: Toward Functional Validation of Cellular and Molecular Phenotypes in Inflammation-Induced Neurodegeneration. In STEM CELLS TRANSLATIONAL MEDICINE. ISSN 2157-6564, MAR 2015, vol. 4, no. 3, p. 252-260. SMALL, S.A. - PETSKO, G.A. Retromer in Alzheimer disease, Parkinson disease and other neurological disorders. In NATURE REVIEWS NEUROSCIENCE. ISSN 1471-003X, MAR 2015, vol. 16, no. 3, p. 126-132. WANG, W.Z. - ZHANG, D. - WEI, Z.W. - WANG, Z.H. - BU, X.L. - YANG, S. - FANG, Q.J. - HU, Z.Y. Label-free detection microarray for novel peptide ligands screening base on MS-SPRi combination. In TALANTA. ISSN 0039-9140, MAR 1 2015, vol. 134, p. 705-711. WEISSMILLER, A.M. - NATERA-NARANJO, O. - REYNA, S.M. - PEARN, M.L. - ZHAO, X.B. - NGUYEN, P. - CHENG, S. - GOLDSTEIN, L.S.B. - TANZI, R.E. - WAGNER, S.L. - MOBLEY, W.C. - WU, C.B. A gamma-Secretase Inhibitor, but Not a gamma-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP. In PLOS ONE. ISSN 1932-6203, FEB 24 2015, vol. 10, no. 2. VAN DER KANT, R. - GOLDSTEIN, L.S.B. Cellular Functions of the Amyloid Precursor Protein from Development to Dementia. In DEVELOPMENTAL CELL. ISSN 1534-5807, FEB 23 2015, vol. 32, no. 4, p. 502-515. HOSSINI, A.M. - MEGGES, M. - PRIGIONE, A. - LICHTNER, B. - TOLIAT, M.R. - WRUCK, W. - SCHROTER, F. - NUERNBERG, P. - KROLL, H. - MAKRANTONAKI, E. - ZOUBOULISS, C.C. - ADJAYE, J. Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks. In BMC GENOMICS. ISSN 1471-2164, FEB 14 2015, vol. 16. SKALOVA, S. - SVADLAKOVA, T. - QURESHI, W.M.S. - DEV, K. - MOKRY, J. Induced Pluripotent Stem Cells and Their Use in Cardiac and Neural Regenerative Medicine. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, FEB 2015, vol. 16, no. 2, p. 4043-4067. GARBETT, K.A. - VERECZKEI, A. - KALMAN, S. - BROWN, J.A. - TAYLOR, W.D. - FALUDI, G. - KORADE, Z. - SHELTON, R.C. - MIRNICS, K. Coordinated Messenger RNA/MicroRNA Changes in Fibroblasts of Patients with Major Depression. In BIOLOGICAL PSYCHIATRY. ISSN 0006-3223, FEB 1 2015, vol. 77, no. 3, p. 256-265. ISOBE, K. - CHENG, Z. - NISHIO, N. - SUGANYA, T. - TANAKA, Y. - ITO, S. Reprint of "iPSCs, aging and age-related diseases". In NEW BIOTECHNOLOGY. ISSN 1871-6784, JAN 25 2015, vol. 32, no. 1, p. 169-179. PAYNE, N.L. - SYLVAINI, A. - O'BRIEN, C. - HERSZFELD, D. - SUN, G. - BERNARD, C.C.A. Application of human induced pluripotent stem cells for modeling and treating neurodegenerative diseases. In NEW BIOTECHNOLOGY. ISSN 1871-6784, JAN 25 2015, vol. 32, no. 1, p. 212-228. OKADA, M. - IKEGAWA, S. - MORIOKA, M. - YAMASHITA, A. - SAITO, A. - SAWAI, H. - MUROTSUKI, J. - OHASHI, H. - OKAMOTO, T. - NISHIMURA, G. - IMAIZUMI, K. - TSUMAKI, N. Modeling type II collagenopathy skeletal dysplasia by directed conversion and induced pluripotent stem cells. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, JAN 15 2015, vol. 24, no. 2, p. 299-313. NIEDERST, E.D. - REYNA, S.M. - GOLDSTEIN, L.S.B. Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing. In MOLECULAR BIOLOGY OF THE CELL. ISSN 1059-1524, JAN 15 2015, vol. 26, no. 2, p. 205-217. CHINTAWAR, S. - GRAF, M. - CADER, Z. Utility of Human Stem Cells for Drug Discovery. In HUMAN-BASED SYSTEMS FOR TRANSLATIONAL RESEARCH. ISSN 2041-3203, 2015, no. 41, p. 162-193. SELFRIDGE, A. - HYUN, N. - CHIANG, C.C. - REYNA, S.M. - WEISSMILLER, A.M. - SHI, L.Z. - PREECE, D. - MOBLEY, W.C. - BERNS, M.W. Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy. In NEUROPHOTONICS. ISSN 2329-423X, JAN-MAR 2015, vol. 2, no. 1. WIETHOFF, S. - ARBER, C. - LI, A. - WRAY, S. - HOULDEN, H. - PATANI, R. Using human induced pluripotent stem cells to model cerebellar disease: Hope and hype. In JOURNAL OF NEUROGENETICS. ISSN 0167-7063, 2015, vol. 29, no. 2-3, p. 95-102. PISTOLLATO, F. - CAVANAUGH, S.E. - CHANDRASEKERA, P.C. A Human-Based Integrated Framework for Alzheimer's Disease Research. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2015, vol. 47, no. 4, p. 857-868. WAN, W.B. - CAO, L. - KALIONIS, B. - XIA, S.J. - TAI, X.T. Applications of Induced Pluripotent Stem Cells in Studying the Neurodegenerative Diseases. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2015. WOOD, L.B. - WINSLOW, A.R. - STRASSER, S.D. Systems biology of neurodegenerative diseases. In INTEGRATIVE BIOLOGY. ISSN 1757-9694, 2015, vol. 7, no. 7, p. 758-775. YAP, M.S. - NATHAN, K.R. - YEO, Y. - LIM, L.W. - POH, C.L. - RICHARDS, M. - LIM, W.L. - OTHMAN, I. - HENG, B.C. Neural Differentiation of Human Pluripotent Stem Cells for Nontherapeutic Applications: Toxicology, Pharmacology, and In Vitro Disease Modeling. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2015. KANO, S. - YUAN, M. - CARDARELLI, R.A. - MAEGAWA, G. - HIGURASHI, N. - GAVAL-CRUZ, M. - WILSON, A.M. - TRISTAN, C. - KONDO, M.A. - CHEN, Y. - KOGA, M. - OBIE, C. - ISHIZUKA, K. - SESHADRI, S. - SRIVASTAVA, R. - KATO, T.A. - HORIUCHI, Y. - SEDLAK, T.W. - LEE, Y. - RAPOPORT, J.L. - HIROSE, S. - OKANO, H. - VALLE, D. - O'DONNELL, P. - SAWA, A. - KAI, M. Clinical Utility of Neuronal Cells Directly Converted from Fibroblasts of Patients for Neuropsychiatric Disorders: Studies of Lysosomal Storage Diseases and Channelopathy. In CURRENT MOLECULAR MEDICINE. ISSN 1566-5240, 2015, vol. 15, no. 2, p. 138-145. MOORE, S. - LIVESEY, F.J. Neural Cell Fate Determination. In PRINCIPLES OF DEVELOPMENTAL GENETICS, 2ND EDITION. 2015, p. 283-296. ZHANG, Z.M. - HUANG, B. - GAO, F. - ZHANG, R.X. Impact of Immune Response on the Use of iPSCs in Disease Modeling. In CURRENT STEM CELL RESEARCH & THERAPY. ISSN 1574-888X, 2015, vol. 10, no. 3, p. 236-244. FRATTINI, E. - RUGGIERI, M. - SALANI, S. - FARAVELLI, I. - ZANETTA, C. - NIZZARDO, M. - SIMONE, C. - MAGRI, F. - CORTI, S. Pluripotent stem cell-based models of spinal muscular atrophy. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, JAN 2015, vol. 64, p. 44-50. BERMAN, D.E. - RINGE, D. - PETSKO, G.A. - SMALL, S.A. The Use of Pharmacological Retromer Chaperones in Alzheimer's Disease and other Endosomal-related Disorders. In NEUROTHERAPEUTICS. ISSN 1933-7213, JAN 2015, vol. 12, no. 1, p. 12-18. GOLDSTEIN, L.S.B. - REYNA, S. - WOODRUFF, G. Probing the Secrets of Alzheimer's Disease Using Human-induced Pluripotent Stem Cell Technology. In NEUROTHERAPEUTICS. ISSN 1933-7213, JAN 2015, vol. 12, no. 1, p. 121-125. KIM, T.W. Drug Repositioning Approaches for the Discovery of New Therapeutics for Alzheimer's Disease. In NEUROTHERAPEUTICS. ISSN 1933-7213, JAN 2015, vol. 12, no. 1, p. 132-142. JOHANNESSEN, C.M. - CLEMONS, P.A. - WAGNER, B.K. Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery. In TRENDS IN GENETICS. ISSN 0168-9525, JAN 2015, vol. 31, no. 1, p. 16-23. TSUMAKI, N. - OKADA, M. - YAMASHITA, A. iPS cell technologies and cartilage regeneration. In BONE. ISSN 8756-3282, JAN 2015, vol. 70, SI, p. 48-54. XIE, Y.Z. - ZHANG, R.X. Neurodegenerative diseases in a dish: the promise of iPSC technology in disease modeling and therapeutic discovery. In NEUROLOGICAL SCIENCES. ISSN 1590-1874, JAN 2015, vol. 36, no. 1, p. 21-27. SANTOSTEFANO, K.E. - HAMAZAKI, T. - BIEL, N.M. - JIN, S.G. - UMEZAWA, A. - TERADA, N. A practical guide to induced pluripotent stem cell research using patient samples. In LABORATORY INVESTIGATION. ISSN 0023-6837, JAN 2015, vol. 95, no. 1, p. 4-13. MUNGENAST, Alison E. - SIEGERT, Sandra - TSAI, Li-Huei. Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, JUN 2016, vol. 73, p. 13-31. HAGGARTY, Stephen J. - SILVA, M. Catarina - CROSS, Alan - BRANDON, Nicholas J. - PERLIS, Roy H. Advancing drug discovery for neuropsychiatric disorders using patient-specific stem cell models. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, JUN 2016, vol. 73, p. 104-115. CHAMI, B. - STEEL, A. J. - DE LA MONTE, S. M. - SUTHERLAND, Greg T. The rise and fall of insulin signaling in Alzheimer's disease. In METABOLIC BRAIN DISEASE. ISSN 0885-7490, JUN 2016, vol. 31, no. 3, p. 497-515. YANG, Juan - LI, Song - HE, Xi-Biao - CHENG, Cheng - LE, Weidong. Induced pluripotent stem cells in Alzheimer's disease: applications for disease modeling and cell-replacement therapy. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, MAY 17 2016, vol. 11. MASSA, Megan G. - GISEVIUS, Barbara - HIRSCHBERG, Sarah - HINZ, Lisa - SCHMIDT, Matthias - GOLD, Ralf - PROCHNOW, Nora - HAGHIKIA, Aiden. Multiple Sclerosis Patient-Specific Primary Neurons Differentiated from Urinary Renal Epithelial Cells via Induced Pluripotent Stem Cells. In PLOS ONE. ISSN 1932-6203, MAY 9 2016, vol. 11, no. 5. PAQUET, Dominik - KWART, Dylan - CHEN, Antonia - SPROUL, Andrew - JACOB, Samson - TEO, Shaun - OLSEN, Kimberly Moore - GREGG, Andrew - NOGGLE, Scott - TESSIER-LAVIGNE, Marc. Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9. In NATURE. ISSN 0028-0836, MAY 5 2016, vol. 533, no. 7601, p. 125-+. ZHENG, Fuyin - FU, Fanfan - CHENG, Yao - WANG, Chunyan - ZHAO, Yuanjin - GU, Zhongze. Organ-on-a-Chip Systems: Microengineering to Biomimic Living Systems. In SMALL. ISSN 1613-6810, MAY 4 2016, vol. 12, no. 17, p. 2253-2282. HOSSINI, Amir M. - QUAST, Annika S. - PLOETZ, Michael - GRAUEL, Katharina - EXNER, Tarik - KUECHLER, Judit - STACHELSCHEID, Harald - EBERLE, Juergen - RABIEN, Anja - MAKRANTONAKI, Evgenia - ZOUBOULIS, Christos C. PI3K/AKT Signaling Pathway Is Essential for Survival of Induced Pluripotent Stem Cells. In PLOS ONE. ISSN 1932-6203, MAY 3 2016, vol. 11, no. 5. XU, Wei - WEISSMILLER, April M. - WHITE, Joseph A., II - FANG, Fang - WANG, Xinyi - WU, Yiwen - PEARN, Matthew L. - ZHAO, Xiaobei - SAWA, Mariko - CHEN, Shengdi - GUNAWARDENA, Shermali - DING, Jianqing - MOBLEY, William C. - WU, Chengbiao. Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration. In JOURNAL OF CLINICAL INVESTIGATION. ISSN 0021-9738, MAY 2016, vol. 126, no. 5, p. 1815-1833. SIMSEK, Senem - ZHOU, Ting - ROBINSON, Christopher L. - TSAI, Su-Yi - CRESPO, Miguel - AMIN, Sadaf - LIN, Xiangyi - HON, Jane - EVANS, Todd - CHEN, Shuibing. Modeling Cystic Fibrosis Using Pluripotent Stem Cell-Derived Human Pancreatic Ductal Epithelial Cells. In STEM CELLS TRANSLATIONAL MEDICINE. ISSN 2157-6564, MAY 2016, vol. 5, no. 5, p. 572-579. KIM, S. - SATO, Y. - MOHAN, P. S. - PETERHOFF, C. - PENSALFINI, A. - RIGOGLIOSO, A. - JIANG, Y. - NIXON, R. A. Evidence that the rab5 effector APPL1 mediates APP-beta CTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, MAY 2016, vol. 21, no. 5, p. 707-716. KALMAN, S. - GARBETT, K. A. - JANKA, Z. - MIRNICS, K. HUMAN DERMAL FIBROBLASTS IN PSYCHIATRY RESEARCH. In NEUROSCIENCE. ISSN 0306-4522, APR 21 2016, vol. 320, p. 105-121. OTANI, Tomoki - MARCHETTO, Maria C. - GAGE, Fred H. - SIMONS, Benjamin D. - LIVESEY, Frederick J. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. In CELL STEM CELL. ISSN 1934-5909, APR 7 2016, vol. 18, no. 4, p. 467-480. VINNAKOTA, Kalyan C. - CHA, Chae Y. - RORSMAN, Patrik - BALABAN, Robert S. - LA GERCHE, Andre - WADE-MARTINS, Richard - BEARD, Daniel A. - JENESON, Jeroen A. L. Improving the physiological realism of experimental models. In INTERFACE FOCUS. ISSN 2042-8898, APR 2016, vol. 6, no. 2. DOULAMES, Vanessa M. - PLANT, Giles W. Induced Pluripotent Stem Cell Therapies for Cervical Spinal Cord Injury. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, APR 2016, vol. 17, no. 4. TIAN, Zuojun - GUO, Fuzheng - BISWAS, Sangita - DENG, Wenbin. Rationale and Methodology of Reprogramming for Generation of Induced Pluripotent Stem Cells and Induced Neural Progenitor Cells. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, APR 2016, vol. 17, no. 4. TELEZHKIN, Vsevolod - SCHNELL, Christian - YAROVA, Polina - YUNG, Sun - COPE, Emma - HUGHES, Alis - THOMPSON, Belinda A. - SANDERS, Philip - GEATER, Charlene - HANCOCK, Jane M. - JOY, Shona - BADDER, Luned - CONNOR-ROBSON, Natalie - COMELLA, Andrea - STRACCIA, Marco - BOMBAU, Georgina - BROWN, Jon T. - CANALS, Josep M. - RANDALL, Andrew D. - ALLEN, Nicholas D. - KEMP, Paul J. Forced cell cycle exit and modulation of GABA(A), CREB, and GSK3 beta signaling promote functional maturation of induced pluripotent stem cell-derived neurons. In AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. ISSN 0363-6143, APR 1 2016, vol. 310, no. 7, p. C520-C541. CHOU, Shih-Jie - TSENG, Wei-Lien - CHEN, Chien-Tsun - LAI, Yu-Fen - CHIEN, Chian-Shiu - CHANG, Yuh-Lih - LEE, Hsin-Chen - WEI, Yau-Huei - CHIOU, Shih-Hwa. Impaired ROS Scavenging System in Human Induced Pluripotent Stem Cells Generated from Patients with MERRF Syndrome. In SCIENTIFIC REPORTS. ISSN 2045-2322, MAR 30 2016, vol. 6. WANG, Lihui - LI, Xirui - HUANG, Wenhao - ZHOU, Tiancheng - WANG, Haitao - LIN, Aiping - HUTCHINS, Andrew Paul - SU, Zhenghui - CHEN, Qianyu - PEI, Duanqing - PAN, Guangjin. TGF beta signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells. In SCIENTIFIC REPORTS. ISSN 2045-2322, MAR 3 2016, vol. 6. HANDEL, Adam E. - CHINTAWAR, Satyan - LALIC, Tatjana - WHITELEY, Emma - VOWLES, Jane - GIUSTACCHINI, Alice - ARGOUD, Karene - SOPP, Paul - NAKANISHI, Mahito - BOWDEN, Rory - COWLEY, Sally - NEWEY, Sarah - AKERMAN, Colin - PONTING, Chris P. - CADER, M. Zameel. Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, MAR 1 2016, vol. 25, no. 5, p. 989-1000. TINCER, Gizem - MASHKARYAN, Violeta - BHATTARAI, Prabesh - KIZIL, Caghan. Neural stem/progenitor cells in Alzheimer's disease. In Yale Journal of Biology and Medicine. ISSN 0044-0086, MAR 2016, vol. 89, no. 1, p. 23-35. JIANG, Ying - RIGOGLIOSO, Andrew - PETERHOFF, Corrinne M. - PAWLIK, Monika - SATO, Yutaka - BLEIWAS, Cynthia - STAVRIDES, Philip - SMILEY, John F. - GINSBERG, Stephen D. - MATHEWS, Paul M. - LEVY, Efrat - NIXON, Ralph A. Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF. In NEUROBIOLOGY OF AGING. ISSN 0197-4580, MAR 2016, vol. 39, p. 90-98. AVIOR, Yishai - SAGI, Ido - BENVENISTY, Nissim. Pluripotent stem cells in disease modelling and drug discovery. In NATURE REVIEWS MOLECULAR CELL BIOLOGY. ISSN 1471-0072, MAR 2016, vol. 17, no. 3, p. 170-182. DI, J. - COHEN, L. S. - CORBO, C. P. - PHILLIPS, G. R. - EL IDRISSI, A. - ALONSO, A. D. Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss. In SCIENTIFIC REPORTS. ISSN 2045-2322, FEB 18 2016, vol. 6. LI, Xueyuan - BAO, Xinjie - WANG, Renzhi. Experimental models of Alzheimer's disease for deciphering the pathogenesis and therapeutic screening (Review). In INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. ISSN 1107-3756, FEB 2016, vol. 37, no. 2, p. 271-283. HUNSBERGER, Joshua G. - RAO, Mahendra - KURTZBERG, Joanne - BULTE, Jeff W. M. - ATALA, Anthony - LAFERLA, Frank M. - GREELY, Henry T. - SAWA, Akira - GANDY, Sam - SCHNEIDER, Lon S. - DORAISWAMY, P. Murali. Accelerating stem cell trials for Alzheimer's disease. In LANCET NEUROLOGY. ISSN 1474-4422, FEB 2016, vol. 15, no. 2, p. 219-230. TANG, Shibing - XIE, Min - CAO, Nan - DING, Sheng. Patient-Specific Induced Pluripotent Stem Cells for Disease Modeling and Phenotypic Drug Discovery. In JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623, JAN 14 2016, vol. 59, no. 1, p. 2-15. OCHALEK, Anna - SZCZESNA, Karolina - PETAZZI, Paolo - KOBOLAK, Julianna - DINNYES, Andras. Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2016. GONZALEZ, Rodolfo - HAMBLIN, Milton H. - LEE, Jean-Pyo. Neural Stem Cell Transplantation and CNS Diseases. In CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. ISSN 1871-5273, 2016, vol. 15, no. 8, p. 881-886. DEVINENI, Aditya - TOHME, Scarlett - KODY, Michael T. - COWLEY, R. Adams - HARRIS, Brent T. Stepping back to move forward: a current review of iPSCs in the fight against Alzheimer's disease. In AMERICAN JOURNAL OF STEM CELLS. ISSN 2160-4150, 2016, vol. 5, no. 3, p. 99-106. SALEM, Haitham - ROCHA, Natalia Pessoa - COLPO, Gabriela Delevati - TEIXEIRA, Antonio Lucio. Moving from the Dish to the Clinical Practice: A Decade of Lessons and Perspectives from the Pre-Clinical and Clinical Stem Cell Studies for Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2016, vol. 53, no. 3, p. 1209-1230. FRIGERIO, Carlo Sala - DE STROOPER, Bart. Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics. In ANNUAL REVIEW OF NEUROSCIENCE, VOL 39. ISSN 0147-006X, 2016, vol. 39, p. 57-79. ZHANG, Weiwei - JIAO, Bin - ZHOU, Miaojin - ZHOU, Tao - SHEN, Lu. Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2016. MENON, Siddharth - SHAILENDRA, Siny - RENDA, Andrea - LONGAKER, Michael - QUARTO, Natalina. An Overview of Direct Somatic Reprogramming: The Ins and Outs of iPSCs. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, JAN 2016, vol. 17, no. 1. CONFALONI, Annamaria - TOSTO, Giuseppe - TATA, Ada Maria. Promising Therapies for Alzheimer's Disease. In CURRENT PHARMACEUTICAL DESIGN. ISSN 1381-6128, 2016, vol. 22, no. 14, p. 2050-2056. XIE, Nina - TANG, Beisha. The Application of Human iPSCs in Neurological Diseases: From Bench to Bedside. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2016. WRUCK, Wasco - SCHROETER, Friederike - ADJAYE, James. Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer's Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2016, vol. 50, no. 4, p. 1065-1082. FERNANDEZ-SANTIAGO, Ruben - EZQUERRA, Mario. Epigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based Models. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2016. CASTRILLO, Juan I. - OLIVER, Stephen G. Alzheimer's as a Systems-Level Disease Involving the Interplay of Multiple Cellular Networks. In SYSTEMS BIOLOGY OF ALZHEIMER'S DISEASE. ISSN 1064-3745, 2016, vol. 1303, p. 3-48. WEICK, Jason P. - KANG, Huining - BONADURER, George F., III - BHATTACHARYYA, Anita. Gene Expression Studies on Human Trisomy 21 iPSCs and Neurons: Towards Mechanisms Underlying Down's Syndrome and Early Alzheimer's Disease-Like Pathologies. In SYSTEMS BIOLOGY OF ALZHEIMER'S DISEASE. ISSN 1064-3745, 2016, vol. 1303, p. 247-265. SAURAT, Nathalie G. - LIVESEY, Frederick J. - MOORE, Steven. Cortical Differentiation of Human Pluripotent Cells for In Vitro Modeling of Alzheimer's Disease. In SYSTEMS BIOLOGY OF ALZHEIMER'S DISEASE. ISSN 1064-3745, 2016, vol. 1303, p. 267-278. CSOEBOENYEIOVA, Maria - DANISOVIC, Lubos - POLAK, Stefan. Recent advances in iPSC technologies involving cardiovascular and neurodegenerative disease modeling. In GENERAL PHYSIOLOGY AND BIOPHYSICS. ISSN 0231-5882, JAN 2016, vol. 35, no. 1, p. 1-12. WANG, Weizhi - FANG, Qiaojun - HU, Zhiyuan. High-Throughput Peptide Screening on a Bimodal Imprinting Chip Through MS-SPRi Integration. In PEPTIDE MICROARRAYS: METHODS AND PROTOCOLS, 2ND EDITION. ISSN 1064-3745, 2016, vol. 1352, p. 111-125. KIM, Sewoong - KIM, Min-Kyoung - OH, Daeyoung - LEE, Sang-Hyuk - KIM, Borah. Induced Pluripotent Stem Cells as a Novel Tool in Psychiatric Research. In PSYCHIATRY INVESTIGATION. ISSN 1738-3684, JAN 2016, vol. 13, no. 1, p. 8-17. HASTON, Kelly M. - FINKBEINER, Steven. Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases. In ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56. ISSN 0362-1642, 2016, vol. 56, p. 489-510. CHOI, Se Hoon - KIM, Young Hye - QUINTI, Luisa - DOO, Rudolph E. Tanzi - KIM, Yeon. 3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish". In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, DEC 9 2016, vol. 11. VELEZ, Jorge I. - LOPERA, Francisco - PATEL, Hardip R. - JOHAR, Angad S. - CAI, Yeping - RIVERA, Dora - TOBON, Carlos - VILLEGAS, Andres - SEPULVEDA-FALLA, Diego - LEHMANN, Shaun G. - EASTEAL, Simon - MASTRONARDI, Claudio A. - ARCOS-BURGOS, Mauricio. Mutations Modifying Sporadic Alzheimer's Disease Age of Onset. In AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. ISSN 1552-4841, DEC 2016, vol. 171, no. 8, p. 1116-1130. SONG, Liqing - WANG, Kai - LI, Yan - YANG, Yong. Nanotopography promoted neuronal differentiation of human induced pluripotent stern cells. In COLLOIDS AND SURFACES B-BIOINTERFACES. ISSN 0927-7765, DEC 1 2016, vol. 148, p. 49-58. DAI, Sheng - LI, Rong - LONG, Yan - TITUS, Steve - ZHAO, Jinghua - HUANG, Ruili - XIA, Menghang - ZHENG, Wei. One-Step Seeding of Neural Stem Cells with Vitronectin-Supplemented Medium for High-Throughput Screening Assays. In JOURNAL OF BIOMOLECULAR SCREENING. ISSN 1087-0571, DEC 2016, vol. 21, no. 10, p. 1112-1124. HILL, Eric - NAGEL, David - PARRI, Rheinallt - COLEMAN, Michael. Stem cell-derived astrocytes: are they physiologically credible?. In JOURNAL OF PHYSIOLOGY-LONDON. ISSN 0022-3751, NOV 15 2016, vol. 594, no. 22, p. 6595-6606. KUIJLAARS, Jacobine - OYELAMI, Tutu - DIELS, Annick - ROHRBACHER, Jutta - VERSWEYVELD, Sofie - MENEGHELLO, Giulia - TUEFFERD, Marianne - VERSTRAELEN, Peter - DETREZ, Jan R. - VERSCHUUREN, Marlies - DE VOS, Winnok H. - MEERT, Theo - PEETERS, Pieter J. - CIK, Miroslav - NUYDENS, Rony - BRONE, Bert - VERHEYEN, An. Sustained synchronized neuronal network activity in a human astrocyte co-culture system. In SCIENTIFIC REPORTS. ISSN 2045-2322, NOV 7 2016, vol. 6. CHAMBERLAIN, Stormy J. Disease modelling using human iPSCs. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, OCT 1 2016, vol. 25, no. R2, p. R173-R181. ZHOU, Shuling - OCHALEK, Anna - SZCZESNA, Karolina - AVCI, Hasan X. - KOBOLAK, Julianna - VARGA, Eszter - RASMUSSEN, Mikkei - HOIST, Bjorn - CIRERA, Susanna - HYTTEL, Poul - FREUDE, Kristine K. - DINNYES, Andras. The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF. In DIFFERENTIATION. ISSN 0301-4681, OCT-NOV 2016, vol. 92, no. 4, p. 183-194. HOEFLING, Corinna - MORAWSKI, Markus - ZEITSCHEL, Ulrike - ZANIER, Elisa R. - MOSCHKE, Katrin - SERDAROGLU, Alperen - CANNEVA, Fabio - VON HOERSTEN, Stephan - DE SIMONI, Maria-Grazia - FORLONI, Gianluigi - JAEGER, Carsten - KREMMER, Elisabeth - ROSSNER, Steffen - LICHTENTHALER, Stefan F. - KUHN, Peer-Hendrik. Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies. In AGING CELL. ISSN 1474-9718, OCT 2016, vol. 15, no. 5, p. 953-963. ENGEL, Martin - DO-HA, Dzung - MUNOZ, Sonia Sanz - OOI, Lezanne. Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, OCT 2016, vol. 73, no. 19, p. 3693-3709. LEE, Han-Kyu - SANCHEZ, Clara Velazquez - CHEN, Mei - MORIN, Peter J. - WELLS, John M. - HANLON, Eugene B. - XIA, Weiming. Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells. In PLOS ONE. ISSN 1932-6203, SEP 29 2016, vol. 11, no. 9. SHERMAN, Sydney A. - PHILLIPS, Jack K. - COSTA, J. Tighe - CHO, Frances S. - OUNGOULIAN, Sevan R. - FINAN, John D. Stretch Injury of Human Induced Pluripotent Stem Cell Derived Neurons in a 96 Well Format. In SCIENTIFIC REPORTS. ISSN 2045-2322, SEP 27 2016, vol. 6. CHANDRASEKARAN, Abinaya - AVCI, Hasan X. - LEIST, Marcel - KOBOLAK, Julianna - DINNYES, Andras. Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research. In FRONTIERS IN CELLULAR NEUROSCIENCE. ISSN 1662-5102, SEP 26 2016, vol. 10. NISHIOKA, Hisae - TOOI, Norie - ISOBE, Takehisa - NAKATSUJI, Norio - AIBA, Kazuhiro. BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models. In SCIENTIFIC REPORTS. ISSN 2045-2322, SEP 19 2016, vol. 6. YAN, Yuanwei - BEJOY, Julie - XIA, Junfei - GUAN, Jingjiao - ZHOU, Yi - LI, Yan. Neural patterning of human induced pluripotent stem cells in 3-D cultures for studying biomolecule-directed differential cellular responses. In ACTA BIOMATERIALIA. ISSN 1742-7061, SEP 15 2016, vol. 42, p. 114-126. RAJA, Waseem K. - MUNGENAST, Alison E. - LIN, Yuan-Ta - KO, Tak - ABDURROB, Fatema - SEO, Jinsoo - TSAI, Li-Huei. Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. In PLOS ONE. ISSN 1932-6203, SEP 13 2016, vol. 11, no. 9. GURWITZ, David. Human iPSC-derived neurons and lymphoblastoid cells for personalized medicine research in neuropsychiatric disorders. In DIALOGUES IN CLINICAL NEUROSCIENCE. ISSN 1294-8322, SEP 2016, vol. 18, no. 3, p. 267-276. ZHANG, Chao - CAO, Jiani - LI, Xiaoyan - XU, Haoyu - WANG, Weixu - WANG, Libin - ZHAO, Xiaoyang - LI, Wei - JIAO, Jianwei - HU, Baoyang - ZHOU, Qi - ZHAO, Tongbiao. Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripotent stem cells. In SCIENCE CHINA-LIFE SCIENCES. ISSN 1674-7305, SEP 2016, vol. 59, no. 9, p. 950-957. ROCHA, Daniela N. - CARVALHO, Eva D. - PEGO, Ana Paula. High-throughput platforms for the screening of new therapeutic targets for neurodegenerative diseases. In DRUG DISCOVERY TODAY. ISSN 1359-6446, SEP 2016, vol. 21, no. 9, p. 1355-1366. YAMAZAKI, Yu - PAINTER, Meghan M. - BU, Guojun - KANEKIYO, Takahisa. Apolipoprotein E as a Therapeutic Target in Alzheimer's Disease: A Review of Basic Research and Clinical Evidence. In CNS DRUGS. ISSN 1172-7047, SEP 2016, vol. 30, no. 9, p. 773-789. BIAN, Hong - BIAN, Wei - LIN, Xiaoying - MA, Zhaoyin - CHEN, Wen - PU, Ying. RNA Interference Silencing of Glycogen Synthase Kinase 3 beta Inhibites Tau Phosphorylation in Mice with Alzheimer Disease. In NEUROCHEMICAL RESEARCH. ISSN 0364-3190, SEP 2016, vol. 41, no. 9, p. 2470-2480. ENGEL, Krysta L. - MACKIEWICZ, Mark - HARDIGAN, Andrew A. - MYERS, Richard M. - SAVIC, Daniel. Decoding transcriptional enhancers: Evolving from annotation to functional interpretation. In SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. ISSN 1084-9521, SEP 2016, vol. 57, p. 40-50. BALEZ, Rachelle - STEINER, Nicole - ENGEL, Martin - MUNOZ, Sonia Sanz - LUM, Jeremy Stephen - WU, Yizhen - WANG, Dadong - VALLOTTON, Pascal - SACHDEV, Perminder - O'CONNOR, Michael - SIDHU, Kuldip - MUENCH, Gerald - OOI, Lezanne. Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer's disease. In SCIENTIFIC REPORTS. ISSN 2045-2322, AUG 12 2016, vol. 6. SABAPATHY, Vikram - KUMAR, Sanjay. hiPSC-derived iMSCs: NextGen MSCs as an advanced therapeutically active cell resource for regenerative medicine. In JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. ISSN 1582-4934, AUG 2016, vol. 20, no. 8, p. 1571-1588. SORIA-VALLES, Clara - LOPEZ-OTIN, Carlos. iPSCs: On the Road to Reprogramming Aging. In TRENDS IN MOLECULAR MEDICINE. ISSN 1471-4914, AUG 2016, vol. 22, no. 8, p. 713-724. IACOVIDES, Demetris - RIZKI, Gizem - LAPATHITIS, Georgios - STRATI, Katerina. Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes. In STEM CELL RESEARCH & THERAPY. ISSN 1757-6512, JUL 29 2016, vol. 7. JOSEPH, Roy - SRIVASTAVA, Om P. - PFISTER, Roswell R. Modeling Keratoconus Using Induced Pluripotent Stem Cells. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. ISSN 0146-0404, JUL 2016, vol. 57, no. 8, p. 3685-3697. CSOBONYEIOVA, Maria - POLAK, Stefan - DANISOVIC, L'ubos. Recent approaches and challenges in iPSCs: modeling and cell-based therapy of Alzheimer's disease. In REVIEWS IN THE NEUROSCIENCES. ISSN 0334-1763, JUL 2016, vol. 27, no. 5, p. 457-464. MERTENS, Jerome - MARCHETTO, Maria C. - BARDY, Cedric - GAGE, Fred H. Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience. In NATURE REVIEWS NEUROSCIENCE. ISSN 1471-003X, JUL 2016, vol. 17, no. 7, p. 424-437. LIANG, Feng - ZHANG, Yiying - HONG, Wooyoung - DONG, Yuanlin - XIE, Zhongcong - QUAN, Qimin. Direct Tracking of Amyloid and Tau Dynamics in Neuroblastoma Cells Using Nanoplasmonic Fiber Tip Probes. In NANO LETTERS. ISSN 1530-6984, JUL 2016, vol. 16, no. 7, p. 3989-3994. PISTOLLATO, Francesca - OHAYON, Elan L. - LAM, Ann - LANGLEY, Gillian R. - NOVAK, Thomas J. - PAMIES, David - PERRY, George - TRUSHINA, Eugenia - WILLIAMS, Robin S. B. - ROHER, Alex E. - HARTUNG, Thomas - HARNAD, Stevan - BARNARD, Neal - MORRIS, Martha Clare - LAI, Mei-Chun - MERKLEY, Ryan - CHANDRASEKERA, P. Charukeshi. Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities. In ONCOTARGET. ISSN 1949-2553, JUN 28 2016, vol. 7, no. 26, p. 38999-39016. PAVONI, Serena - JARRAY, Rafika - NASSOR, Ferid - GUYOT, Anne-Cecile - COTTIN, Steve - RONTARD, Jessica - MIKOL, Jacqueline - MABONDZO, Aloise - DESLYS, Jean-Philippe - YATES, Frank. Small-molecule induction of A beta-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes. In PLOS ONE. ISSN 1932-6203, 2018, vol. 13, no. 12, pp. MURATORE, Christina R. - ZHOU, Constance - LIAO, Meichen - FERNANDEZ, Marty A. - TAYLOR, Walter M. - LAGOMARSINO, Valentina N. - PEARSE, Richard V. - RICE, Heather C. - NEGRI, Joseph M. - HE, Amy - SRIKANTH, Priya - CALLAHAN, Dana G. - SHIN, Taehwan - ZHOU, Monica - BENNETT, David A. - NOGGLE, Scott - LOVE, J. Christopher - SELKOE, Dennis J. - YOUNG-PEARSE, Tracy L. Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability. In STEM CELL REPORTS. ISSN 2213-6711, 2017, vol. 9, no. 6, pp. 1868-1884. SHIROTANI, Keiro - MATSUO, Kazuya - OHTSUKI, Sumio - MASUDA, Takeshi - ASAI, Masashi - KUTOKU, Yumiko - OHSAWA, Yutaka - SUNADA, Yoshihide - KONDO, Takayuki - INOUE, Haruhisa - IWATA, Nobuhisa. A simplified and sensitive method to identify Alzheimer's disease biomarker candidates using patient-derived induced pluripotent stem cells (iPSCs). In JOURNAL OF BIOCHEMISTRY. ISSN 0021-924X, 2017, vol. 162, no. 6, pp. 391-394. OCHALEK, Anna - MIHALIK, Balazs - AVCI, Hasan X. - CHANDRASEKARAN, Abinaya - TEGLASI, Annamaria - BOCK, Istvan - LO GIUDICE, Maria - TANCOS, Zsuzsanna - MOLNAR, Kinga - LASZLO, Lajos - NIELSEN, Jorgen E. - HOLST, Bjorn - FREUDE, Kristine - HYTTEL, Poul - KOBOLAK, Julianna - DINNYES, Andras. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2017, vol. 9, no., pp. INOUE, Keiichi - OLIVEIRA, Luis M. A. - ABELIOVICH, Asa. CRISPR Transcriptional Activation Analysis Unmasks an Occult gamma-Secretase Processivity Defect in Familial Alzheimer's Disease Skin Fibroblasts. In CELL REPORTS. ISSN 2211-1247, 2017, vol. 21, no. 7, pp. 1727-1736. MANN, Aman P. - SCODELLER, Pablo - HUSSAIN, Sazid - BRAUN, Gary B. - MOLDER, Tarmo - TOOME, Kadri - AMBASUDHAN, Rajesh - TEESALU, Tambet - LIPTON, Stuart A. - RUOSLAHTI, Erkki. Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease. In NATURE COMMUNICATIONS. ISSN 2041-1723, 2017, vol. 8, no., pp. LIU, Beihui - TESCHEMACHER, A. G. - KASPAROV, Sergey. Neuroprotective Potential of Astroglia. In JOURNAL OF NEUROSCIENCE RESEARCH. ISSN 0360-4012, 2017, vol. 95, no. 11, pp. 2126-2139. DE OLIVEIRA, Maira Souza - SALDANHA-ARAUJO, Felipe - DE GOES, Alfredo Miranda - COSTA, Fabricio F. - DE CARVALHO, Juliana Lott. Stem cells in cardiovascular diseases: turning bad days into good ones. In DRUG DISCOVERY TODAY. ISSN 1359-6446, 2017, vol. 22, no. 11, pp. 1730-1739. IMM, Jennifer - KERRIGAN, Talitha L. - JEFFRIES, Aaron - LUNNON, Katie. Using induced pluripotent stem cells to explore genetic and epigenetic variation associated with Alzheimer's disease. In EPIGENOMICS. ISSN 1750-1911, 2017, vol. 9, no. 11, pp. 1455-1468. LOPEZ-LEON, Micaela - OUTEIRO, Tiago F. - GOYA, Rodolfo G. Cell reprogramming: Therapeutic potential and the promise of rejuvenation for the aging brain. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, 2017, vol. 40, no., pp. 168-181. PRAMANIK, Subrata - SULISTIO, Yanuar Alan - HEESE, Klaus. Neurotrophin Signaling and Stem Cells-Implications for Neurodegenerative Diseases and Stem Cell Therapy. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, 2017, vol. 54, no. 9, pp. 7401-7459. ROBBINS, J. P. - PRICE, J. Human induced pluripotent stem cells as a research tool in Alzheimer's disease. In PSYCHOLOGICAL MEDICINE. ISSN 0033-2917, 2017, vol. 47, no. 15, pp. 2587-2592. POON, Anna - ZHANG, Yu - CHANDRASEKARAN, Abinaya - PHANTHONG, Phetcharat - SCHMID, Benjamin - NIELSEN, Troels T. - FREUDE, Kristine K. Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges. In NEW BIOTECHNOLOGY. ISSN 1871-6784, 2017, vol. 39, no., pp. 190-198. SEO, Jinsoo - KRITSKIY, Oleg - WATSON, L. Ashley - BARKER, Scarlett J. - DEY, Dilip - RAJA, Waseem K. - LIN, Yuan-Ta - KO, Tak - CHO, Sukhee - PENNEY, Jay - SILVA, M. Catarina - SHERIDAN, Steven D. - LUCENTE, Diane - GUSELLA, James F. - DICKERSON, Bradford C. - HAGGARTY, Stephen J. - TSAI, Li-Huei. Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, 2017, vol. 37, no. 41, pp. 9917-9924. WEI, Zheng Z. - ZHU, Yan-Bing - ZHANG, James Y. - MCCRARY, Myles R. - WANG, Song - ZHANG, Yong-Bo - YU, Shan-Ping - WEI, Ling. Priming of the Cells: Hypoxic Preconditioning for Stem Cell Therapy. In CHINESE MEDICAL JOURNAL. ISSN 0366-6999, 2017, vol. 130, no. 19, pp. 2361-2374. MENG, Shu - CHANDA, Palas - THANDAVARAYAN, Rajarajan A. - COOKE, John P. Transflammation: Innate immune signaling in nuclear reprogramming. In ADVANCED DRUG DELIVERY REVIEWS. ISSN 0169-409X, 2017, vol. 120, no., pp. 133-141. URBANCIC, Vasja - BUTLER, Richard - RICHIER, Benjamin - PETER, Manuel - MASON, Julia - LIVESEY, Frederick J. - HOLT, Christine E. - GALLOP, Jennifer L. Filopodyan: An open-source pipeline for the analysis of filopodia. In JOURNAL OF CELL BIOLOGY. ISSN 0021-9525, 2017, vol. 216, no. 10, pp. 3405-3422. SMITH, Derek K. - HE, Miao - ZHANG, Chun-Li - ZHENG, Jialin C. The therapeutic potential of cell identity reprogramming for the treatment of aging-related neurodegenerative disorders. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, 2017, vol. 157, no., pp. 212-229. SMALL, Scott A. - SIMOES-SPASSOV, Sabrina - MAYEUX, Richard - PETSKO, Gregory A. Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer's Disease. In TRENDS IN NEUROSCIENCES. ISSN 0166-2236, 2017, vol. 40, no. 10, pp. 592-602. REILLY, Patrick - WINSTON, Charisse N. - BARON, Kelsey R. - TREJO, Margarita - ROCKENSTEIN, Edward M. - AKERS, Johnny C. - KFOURY, Najla - DIAMOND, Marc - MASLIAH, Eliezer - RISSMAN, Robert A. - YUAN, Shauna H. Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, 2017, vol. 106, no., pp. 222-234. KANG, Sai - CHEN, Xiaoxia - GONG, Siyi - YU, Panpan - YAU, SukYu - SU, Zhenghui - ZHOU, Libing - YU, Jiandong - PAN, Guangjin - SHI, Lingling. Characteristic analyses of a neural differentiation model from iPSC-derived neuron according to morphology, physiology, and global gene expression pattern. In SCIENTIFIC REPORTS. ISSN 2045-2322, 2017, vol. 7, no., pp. HUNG, Sandy S. C. - KHAN, Shahnaz - LO, Camden Y. - HEWITT, Alex W. - WONG, Raymond C. B. Drug discovery using induced pluripotent stem cell models of neurodegenerative and ocular diseases. In PHARMACOLOGY & THERAPEUTICS. ISSN 0163-7258, 2017, vol. 177, no., pp. 32-43. HAN, Biao - NIA, Hadi T. - WANG, Chao - CHANDRASEKARAN, Prashant - LI, Qing - CHERY, Daphney R. - LI, Hao - GRODZINSKY, Alan J. - HAN, Lin. AFM-Nanomechanical Test: An Interdisciplinary Tool That Links the Understanding of Cartilage and Meniscus Biomechanics, Osteoarthritis Degeneration, and Tissue Engineering. In ACS BIOMATERIALS SCIENCE & ENGINEERING. ISSN 2373-9878, 2017, vol. 3, no. 9, pp. 2033-2049. ACUN, Aylin - ZORLUTUNA, Pinar. Engineered myocardium model to study the roles of HIF-1 alpha and HIF1A-AS1 in paracrine-only signaling under pathological level oxidative stress. In ACTA BIOMATERIALIA. ISSN 1742-7061, 2017, vol. 58, no., pp. 323-336. KIM, Hongwon - YOO, Junsang - SHIN, Jaein - CHANG, Yujung - JUNG, Junghyun - JO, Dong-Gyu - KIM, Janghwan - JANG, Wonhee - LENGNER, Christopher J. - KIM, Byung-Soo - KIM, Jongpil. Modelling APOE epsilon 3/4 allele-associated sporadic Alzheimer's disease in an induced neuron. In BRAIN. ISSN 0006-8950, 2017, vol. 140, no., pp. 2193-2209. NIXON, Ralph A. Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease. In FASEB JOURNAL. ISSN 0892-6638, 2017, vol. 31, no. 7, pp. 2729-2743. WRAY, Selina. Modeling tau pathology in human stem cell derived neurons. In BRAIN PATHOLOGY. ISSN 1015-6305, 2017, vol. 27, no. 4, pp. 525-529. LAUSCHKE, Karin - FREDERIKSEN, Lise - HALL, Vanessa Jane. Paving the Way Toward Complex Blood-Brain Barrier Models Using Pluripotent Stem Cells. In STEM CELLS AND DEVELOPMENT. ISSN 1547-3287, 2017, vol. 26, no. 12, pp. 857-874. ARBER, Charles - LOVEJOY, Christopher - WRAY, Selina. Stem cell models of Alzheimer's disease: progress and challenges. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2017, vol. 9, no., pp. YASUI, Tetsuro - UEZONO, Naohiro - NAKASHIMA, Hideyuki - NOGUCHI, Hirofumi - MATSUDA, Taito - NODA-ANDOH, Tomoko - OKANO, Hideyuki - NAKASHIMA, Kinichi. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. In STEM CELL REPORTS. ISSN 2213-6711, 2017, vol. 8, no. 6, pp. 1743-1756. ULIASSI, Elisa - GANDINI, Annachiara - PERONE, Rosaria Carmela - BOLOGNESI, Maria Laura. Neuroregeneration versus neurodegeneration: toward a paradigm shift in Alzheimer's disease drug discovery. In FUTURE MEDICINAL CHEMISTRY. ISSN 1756-8919, 2017, vol. 9, no. 10, pp. 995-1013. SHIROTANI, Keiro - ASAI, Masashi - IWATA, Nobuhisa. Paradigm shift from diagnosing patients based on common symptoms to categorizing patients into subtypes with different pathogenic mechanisms to guide treatment for Alzheimer's disease. In JOURNAL OF BIOCHEMISTRY. ISSN 0021-924X, 2017, vol. 161, no. 6, pp. 463-470. NEGORO, Takaharu - OKURA, Hanayuki - MATSUYAMA, Akifumi. Induced Pluripotent Stem Cells: Global Research Trends. In BIORESEARCH OPEN ACCESS. ISSN 2164-7860, 2017, vol. 6, no. 1, pp. 63-73. CRONIN, Peter - MCCARTHY, Michael J. - LIM, Andrew S. P. - SALMON, David P. - GALASKO, Douglas - MASLIAH, Eliezer - DE JAGER, Philip L. - BENNETT, David A. - DESPLATS, Paula. Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1. In ALZHEIMERS & DEMENTIA. ISSN 1552-5260, 2017, vol. 13, no. 6, pp. 689-700. KAMPMANN, Martin. A CRISPR Approach to Neurodegenerative Diseases. In TRENDS IN MOLECULAR MEDICINE. ISSN 1471-4914, 2017, vol. 23, no. 6, pp. 483-485. PARR, C. J. C. - YAMANAKA, S. - SAITO, H. An update on stem cell biology and engineering for brain development. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2017, vol. 22, no. 6, pp. 808-819. QIANG, Liang - RAO, Anand N. - MOSTOSLAVSKY, Gustavo - JAMES, Marianne F. - COMFORT, Nicole - SULLIVAN, Kimberly - BAAS, Peter W. Reprogramming cells from Gulf War veterans into neurons to study Gulf War illness. In NEUROLOGY. ISSN 0028-3878, 2017, vol. 88, no. 20, pp. 1968-1975. BROWNJOHN, Philip W. - SMITH, James - PORTELIUS, Erik - SERNEELS, Lutgarde - KVARTSBERG, Hlin - DE STROOPER, Bart - BLENNOW, Kaj - ZETTERBERG, Henrik - LIVESEY, Frederick J. Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease. In STEM CELL REPORTS. ISSN 2213-6711, 2017, vol. 8, no. 4, pp. 870-882. COOPER, Daniel J. - ZUNINO, Giulia - BIXBY, John L. - LEMMON, Vance P. Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, 2017, vol. 80, no., pp. 161-169. MARINOWIC, Daniel Rodrigo - MAJOLO, Fernanda - SEBBEN, Alessandra Deise - DA SILVA, Vinicius Duval - LOPES, Tiago Giuliani - PAGLIOLI, Eliseu - PALMINI, Andre - MACHADO, Denise Cantarelli - DA COSTA, Jaderson Costa. Induced pluripotent stem cells from patients with focal cortical dysplasia and refractory epilepsy. In MOLECULAR MEDICINE REPORTS. ISSN 1791-2997, 2017, vol. 15, no. 4, pp. 2049-2056. GUIX, Francesc X. - SANNERUD, Ragna - BERDITCHEVSKI, Fedor - ARRANZ, Amaia M. - HORRE, Katrien - SNELLINX, An - THATHIAH, Amantha - SAIDO, Takaomi - SAITO, Takashi - RAJESH, Sundaresan - OVERDUIN, Michael - KUMAR-SINGH, Samir - RADAELLI, Enrico - CORTHOUT, Nikky - COLOMBELLI, Julien - TOSI, Sebastien - MUNCK, Sebastian - SALAS, Isabel H. - ANNAERT, Wim - DE STROOPER, Bart. Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments. In MOLECULAR NEURODEGENERATION. ISSN 1750-1326, 2017, vol. 12, no., pp. JONES, V. C. - ATKINSON-DELL, R. - VERKHRATSKY, A. - MOHAMET, L. Aberrant iPSC-derived human astrocytes in Alzheimer's disease. In CELL DEATH & DISEASE. ISSN 2041-4889, 2017, vol. 8, no., pp. GAO, Rui - XIU, Wenchao - ZHANG, Linfeng - ZANG, Ruge - YANG, Lei - WANG, Chenfei - WANG, Min - WANG, Mingzhu - YI, Li - TANG, Yuanyuan - GAO, Yawei - WANG, Hong - XI, Jiajie - LIU, Wenqiang - WANG, Yixuan - WEN, Xuejun - YU, Yongchun - ZHANG, Yong - CHEN, Liang - CHEN, Jiayu - GAO, Shaorong. Direct induction of neural progenitor cells transiently passes through a partially reprogrammed state. In BIOMATERIALS. ISSN 0142-9612, 2017, vol. 119, no., pp. 53-67. BAHMAD, Hisham - HADADEH, Ola - CHAMAA, Farah - CHEAITO, Katia - DARWISH, Batoul - MAKKAWI, Ahmad-Kareem - ABOU-KHEIR, Wassim. Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, 2017, vol. 10, no., pp. ARMIJO, Enrique - GONZALEZ, Cesar - SHAHNAWAZ, Mohammad - FLORES, Andrea - DAVIS, Brian - SOTO, Claudio. Increased susceptibility to A beta toxicity in neuronal cultures derived from familial Alzheimer's disease (PSEN1-A246E) induced pluripotent stem cells. In NEUROSCIENCE LETTERS. ISSN 0304-3940, 2017, vol. 639, no., pp. 74-81. GOPALAKRISHNAN, Suhasni - HOR, Pooja - ICHIDA, Justin K. New approaches for direct conversion of patient fibroblasts into neural cells. In BRAIN RESEARCH. ISSN 0006-8993, 2017, vol. 1656, no., pp. 2-13. CORNACCHIA, Daniela - STUDER, Lorenz. Back and forth in time: Directing age in iPSC-derived lineages. In BRAIN RESEARCH. ISSN 0006-8993, 2017, vol. 1656, no., pp. 14-26. SULLIVAN, Sarah E. - YOUNG-PEARSE, Tracy L. Induced pluripotent stem cells as a discovery tool for Alzheimer's disease. In BRAIN RESEARCH. ISSN 0006-8993, 2017, vol. 1656, no., pp. 98-106. UGBODE, Chris - HU, Yuhan - WHALLEY, Benjamin - PEERS, Chris - RATTRAY, Marcus - DALLAS, Mark L. Astrocytic transporters in Alzheimer's disease. In BIOCHEMICAL JOURNAL. ISSN 0264-6021, 2017, vol. 474, no., pp. 333-355. SHI, Yanhong - INOUE, Haruhisa - WU, Joseph C. - YAMANAKA, Shinya. Induced pluripotent stem cell technology: a decade of progress. In NATURE REVIEWS DRUG DISCOVERY. ISSN 1474-1776, 2017, vol. 16, no. 2, pp. 115-130. DRUMMOND, Eleanor - WISNIEWSKI, Thomas. Alzheimer's disease: experimental models and reality. In ACTA NEUROPATHOLOGICA. ISSN 0001-6322, 2017, vol. 133, no. 2, pp. 155-175. YANG, Juan - ZHAO, Hanzhi - MA, Yu - SHI, Guilai - SONG, Jian - TANG, Yu - LI, Song - LI, Ting - LIU, Nan - TANG, Fan - GU, Junjie - ZHANG, Lingling - ZHANG, Zhuohua - ZHANG, Xiaohui - JIN, Ying - LE, Weidong. Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. In ONCOTARGET. ISSN 1949-2553, 2017, vol. 8, no. 5, pp. 7900-7913. LAM, Rebecca S. - TOEPFER, Felix M. - WOOD, Phillip G. - BUSSKAMP, Volker - BAMBERG, Ernst. Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures. In PLOS ONE. ISSN 1932-6203, 2017, vol. 12, no. 1, pp. HARASTA, Anne E. - ITTNER, Lars M. Alzheimer's Disease: Insights from Genetic Mouse Models and Current Advances in Human IPSC-Derived Neurons. In NEURODEGENERATIVE DISEASES: PATHOLOGY, MECHANISMS, AND POTENTIAL THERAPEUTIC TARGETS. ISSN 2190-5215, 2017, vol. 15, no., pp. 3-29. RIEMENS, Renzo J. M. - SOARES, Edilene S. - ESTELLER, Manel - DELGADO-MORALES, Raul. Stem Cell Technology for (Epi)genetic Brain Disorders. In NEUROEPIGENOMICS IN AGING AND DISEASE. ISSN 0065-2598, 2017, vol. 978, no., pp. 443-475. PATHARAGULPONG, Atipat. Stem Cells in Alzheimer's Disease Therapy. In NEUROLOGICAL REGENERATION. ISSN 2365-4198, 2017, vol., no., pp. 49-64. SOLDNER, Frank - JAENISCH, Rudolf. In Vitro Modeling of Complex Neurological Diseases. In GENOME EDITING IN NEUROSCIENCES. ISSN 0945-6082, 2017, vol., no., pp. 1-19. CHOI, Se Hoon - D'AVANZO, Carla - KIM, Young Hye - BYLYKBASHI, Enjana - HEBISCH, Matthias - BRUESTLE, Oliver - TANZI, Ruldolph E. - KIM, Doo Yeon. Three-Dimensional Cultures of Human Neural Stem Cells: An Application for Modeling Alzheimer's Disease Pathogenesis. In STEM CELL TECHNOLOGIES IN NEUROSCIENCE. ISSN 0893-2336, 2017, vol. 126, no., pp. 1-18. NAIR, Meera - SANDHU, Sardul Singh - SHARMA, Anil Kumar. Induced Pluripotent Stem Cell Technology: A Paradigm Shift in Medical Science for Drug Screening and Disease Modeling. In CURRENT MEDICINAL CHEMISTRY. ISSN 0929-8673, 2017, vol. 24, no. 39, pp. 4368-4398. SCHORK, N. J. - NAZOR, K. Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond. In ADVANCES IN GENETICS, VOL 97. ISSN 0065-2660, 2017, vol. 97, no., pp. 81-113. CLAES, Christel - TERRYN, Joke - VERFAILLIE, Catherine M. STEM CELLS IN NEURODEGENERATION: MIND THE GAP. In DISEASE-MODIFYING TARGETS IN NEURODEGENERATIVE DISORDERS: PAVING THE WAY FOR DISEASE-MODIFYING THERAPIES, 2017, vol., no., pp. 81-100. PETROV, A. M. - KASIMOV, M. R. - ZEFIROV, A. L. Cholesterol in the Pathogenesis of Alzheimer's, Parkinson's Diseases and Autism: Link to Synaptic Dysfunction. In ACTA NATURAE. ISSN 2075-8251, 2017, vol. 9, no. 1, pp. 26-37. ZOLLO, Alen - ALLEN, Zoe - RASMUSSEN, Helle F. - IANNUZZI, Filomena - SHI, Yichen - LARSEN, Agnete - MAIER, Thorsten J. - MATRONE, Carmela. Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele. In NEURAL PLASTICITY. ISSN 2090-5904, 2017, vol., no., pp. HANE, Francis T. - LEE, Brenda Y. - LEONENKO, Zoya. Recent Progress in Alzheimer's Disease Research, Part 1: Pathology. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2017, vol. 57, no. 1, pp. 1-28. GOLPICH, Mojtaba - AMINI, Elham - MOHAMED, Zahurin - ALI, Raymond Azman - IBRAHIM, Norlinah Mohamed - AHMADIANI, Abolhassan. Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment. In CNS NEUROSCIENCE & THERAPEUTICS. ISSN 1755-5930, 2017, vol. 23, no. 1, pp. 5-22. SUH, Wonhee. A new era of disease modeling and drug discovery using induced pluripotent stem cells. In ARCHIVES OF PHARMACAL RESEARCH. ISSN 0253-6269, 2017, vol. 40, no. 1, pp. 1-12. PEN, A. E. - JENSEN, U. B. Current status of treating neurodegenerative disease with induced pluripotent stem cells. In ACTA NEUROLOGICA SCANDINAVICA. ISSN 0001-6314, 2017, vol. 135, no. 1, pp. 57-72. JUNG-KLAWITTER, Sabine - OPLADEN, Thomas. Induced pluripotent stem cells (iPSCs) as model to study inherited defects of neurotransmission in inborn errors of metabolism. In JOURNAL OF INHERITED METABOLIC DISEASE. ISSN 0141-8955, 2018, vol. 41, no. 6, pp. 1103-1116. JUNG, Yeong Ju - KIM, Yoon Ha - BHALLA, Mridula - LEE, Sung Bae - SEO, Jinsoo. Genomics: New Light on Alzheimer's Disease Research. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. ISSN 1422-0067, 2018, vol. 19, no. 12, pp. CANTLEY, William L. - DU, Chuang - LOMOIO, Selene - DEPALMA, Thomas - PEIRENT, Emily - KLEINKNECHT, Dominic - HUNTER, Martin - TANG-SCHOMER, Min D. - TESCO, Giuseppina - KAPLAN, David L. Functional and Sustainable 3D Human Neural Network Models from Pluripotent Stem Cells. In ACS BIOMATERIALS SCIENCE & ENGINEERING. ISSN 2373-9878, 2018, vol. 4, no. 12, pp. 4278-4288. GONZALEZ, Cesar - ARMIJO, Enrique - BRAVO-ALEGRIA, Javiera - BECERRA-CALIXTO, Andrea - MAYS, Charles E. - SOTO, Claudio. Modeling amyloid beta and tau pathology in human cerebral organoids. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2018, vol. 23, no. 12, pp. 2363-2374. ROWLAND, Helen A. - HOOPER, Nigel M. - KELLETT, Katherine A. B. Modelling Sporadic Alzheimer's Disease Using Induced Pluripotent Stem Cells. In NEUROCHEMICAL RESEARCH. ISSN 0364-3190, 2018, vol. 43, no. 12, pp. 2179-2198. WILSON, Emily S. - NEWELL-LITWA, Karen. Stem cell models of human synapse development and degeneration. In MOLECULAR BIOLOGY OF THE CELL. ISSN 1059-1524, 2018, vol. 29, no. 24, pp. 2913-2921. JANCZURA, Karolina J. - VOLMAR, Claude-Henry - SARTOR, Gregory C. - RAO, Sunil J. - RICCIARDI, Natalie R. - LAMBERT, Guerline - BROTHERS, Shaun P. - WAHLESTEDT, Claes. Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model. In PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ISSN 0027-8424, 2018, vol. 115, no. 47, pp. E11148-E11157. REAL, Raquel - PETER, Manuel - TRABALZA, Antonio - KHAN, Shabana - SMITH, Mark A. - DOPP, Joana - BARNES, Samuel J. - MOMOH, Ayiba - STRANO, Alessio - VOLPI, Emanuela - KNOTT, Graham - LIVESEY, Frederick J. - DE PAOLA, Vincenzo. In vivo modeling of human neuron dynamics and Down syndrome. In SCIENCE. ISSN 0036-8075, 2018, vol. 362, no. 6416, pp. 793-+. YUAN, Shauna H. - HIRAMATSU, Nobuhiko - LIU, Qing - SUN, Xuehan Victoria - LENH, David - CHAN, Priscilla - CHIANG, Karen - KOO, Edward H. - KAO, Aimee Wi - LITVAN, Irene - LIN, Jonathan H. Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress. In HUMAN MOLECULAR GENETICS. ISSN 0964-6906, 2018, vol. 27, no. 22, pp. 3951-3963. CHANG, Chia-Yu - TING, Hsiao-Chien - LIU, Ching-Ann - SU, Hong-Lin - CHIOU, Tzyy-Wen - HARN, Horng-Jyh - LIN, Shinn-Zong. Induced Pluripotent Stem Cells A Powerful Neurodegenerative Disease Modeling Tool for Mechanism Study and Drug Discovery. In CELL TRANSPLANTATION. ISSN 0963-6897, 2018, vol. 27, no. 11, pp. 1588-1602. TAJIRI, Susumu - YAMANAKA, Shuichiro - FUJIMOTO, Toshinari - MATSUMOTO, Kei - TAGUCHI, Atsuhiro - NISHINAKAMURA, Ryuichi - OKANO, Hirotaka James - YOKOO, Takashi. Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration. In SCIENTIFIC REPORTS. ISSN 2045-2322, 2018, vol. 8, no., pp. DURBIN, Matthew D. - CADAR, Adrian G. - CHUN, Young Wook - HONG, Charles C. Investigating pediatric disorders with induced pluripotent stem cells. In PEDIATRIC RESEARCH. ISSN 0031-3998, 2018, vol. 84, no. 4, pp. 499-508. HAAPASALO, Annakaisa - HILTUNEN, Mikko. A report from the 8th Kuopio Alzheimer Symposium. In NEURODEGENERATIVE DISEASE MANAGEMENT. ISSN 1758-2024, 2018, vol. 8, no. 5, pp. 289-299. YU, Qiujian - LIU, Huimin - SANG, Shaoming - CHEN, Lulan - ZHAO, Yingya - WANG, Yun - ZHONG, Chunjiu. Thiamine deficiency contributes to synapse and neural circuit defects. In BIOLOGICAL RESEARCH. ISSN 0716-9760, 2018, vol. 51, no., pp. TAOUFIK, Era - KOUROUPI, Georgia - ZYGOGIANNI, Ourania - MATSAS, Rebecca. Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models. In OPEN BIOLOGY. ISSN 2046-2441, 2018, vol. 8, no. 9, pp. TOFARIS, George K. - BUCKLEY, Noel J. Convergent molecular defects underpin diverse neurodegenerative diseases. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. ISSN 0022-3050, 2018, vol. 89, no. 9, pp. 962-969. RANJAN, Vivek Damodar - QIU, Lifeng - TAN, Eng King - ZENG, Li - ZHANG, Yilei. Modelling Alzheimer's disease: Insights from in vivo to in vitro three-dimensional culture platforms. In JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. ISSN 1932-6254, 2018, vol. 12, no. 9, pp. 1944-1958. KARCH, Celeste M. - HERNANDEZ, Damian - WANG, Jen-Chyong - MARSH, Jacob - HEWITT, Alex W. - HSU, Simon - NORTON, Joanne - LEVITCH, Denise - DONAHUE, Tamara - SIGURDSON, Wendy - GHETTI, Bernardino - FARLOW, Martin - CHHATWAL, Jasmeer - BERMAN, Sarah - CRUCHAGA, Carlos - MORRIS, John C. - BATEMAN, Randall J. - PEBAY, Alice - GOATE, Alison M. Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network. In ALZHEIMERS RESEARCH & THERAPY. ISSN 1758-9193, 2018, vol. 10, no., pp. FONG, Lauren K. - YANG, Max M. - CHAVES, Rodrigo dos Santos - REYNA, Sol M. - LANGNESS, Vanessa F. - WOODRUFF, Grace - ROBERTS, Elizabeth A. - YOUNG, Jessica E. - GOLDSTEIN, Lawrence S. B. Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid- clearance in human astrocytes. In JOURNAL OF BIOLOGICAL CHEMISTRY. ISSN 0021-9258, 2018, vol. 293, no. 29, pp. 11341-11357. BERRY, Bonnie J. - SMITH, Alec S. T. - LONG, Christopher J. - MARTIN, Candace C. - HICKMAN, James J. Physiological A beta Concentrations Produce a More Biomimetic Representation of the Alzheimer's Disease Phenotype in iPSC Derived Human Neurons. In ACS CHEMICAL NEUROSCIENCE. ISSN 1948-7193, 2018, vol. 9, no. 7, pp. 1693-1701. SONG, Chang-Geng - ZHANG, Yi-Zhe - WU, Hai-Ning - CAO, Xiu-Li - GUO, Chen-Jun - LI, Yong-Qiang - ZHENG, Min-Hua - HAN, Hua. Stem cells: a promising candidate to treat neurological disorders. In NEURAL REGENERATION RESEARCH. ISSN 1673-5374, 2018, vol. 13, no. 7, pp. 1294-1304. PARK, Joseph - WETZEL, Isaac - MARRIOTT, Ian - DREAU, Didier - D'AVANZO, Carla - KIM, Doo Yeon - TANZI, Rudolph E. - CHO, Hansang. A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer's disease. In NATURE NEUROSCIENCE. ISSN 1097-6256, 2018, vol. 21, no. 7, pp. 941-+. MENG, Shu - CHANDA, Palas - THANDAVARAYAN, Rajarajan A. - COOKE, John P. Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming. In ANTIOXIDANTS & REDOX SIGNALING. ISSN 1523-0864, 2018, vol. 29, no. 2, pp. 205-218. YAN, Yuanwei - SONG, Liqing - BEJOY, Julie - ZHAO, Jing - KANEKIYO, Takahisa - BU, Guojun - ZHOU, Yi - LI, Yan. Modeling Neurodegenerative Microenvironment Using Cortical Organoids Derived from Human Stem Cells. In TISSUE ENGINEERING PART A. ISSN 1937-3341, 2018, vol. 24, no. 13-14, pp. 1125-1137. CHEN, Mei - LEE, Han-Kyu - MOO, Lauren - HANLON, Eugene - STEIN, Thor - XIA, Weiming. Common proteomic profiles of induced pluripotent stem cell-derived three-dimensional neurons and brain tissue from Alzheimer patients. In JOURNAL OF PROTEOMICS. ISSN 1874-3919, 2018, vol. 182, no., pp. 21-33. WLODAREK, Lukasz - LIM, Fievel. Rejuvenating the Elderly A Scientific Approach for Tackling Geriatric Intensive Care. In UNIVERSITY OF TORONTO MEDICAL JOURNAL. ISSN 0833-2207, 2018, vol. 95, no. 3, pp. 36-40. WANG YUAN-YUAN - BAO XIAO-MING - LING YUN-XIANG - WANG QIN-WEN - XU SHU-JUN. Recent Progress of Induced Pluripotent Stem Cells in Alzheimer's Disease. In PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. ISSN 1000-3282, 2018, vol. 45, no. 6, pp. 637-643. FLAMIER, Anthony - EL HAJJAR, Jida - ADJAYE, James - FERNANDES, Karl J. - ABDOUH, Mohamed - BERNIER, Gilbert. Modeling Late-Onset Sporadic Alzheimer''s Disease through BMI1 Deficiency. In CELL REPORTS. ISSN 2211-1247, 2018, vol. 23, no. 9, pp. 2653-2666. POPLAWSKI, Gunnar H. D. - LIE, Richard - HUNT, Matt - KUMAMARU, Hiromi - KAWAGUCHI, Riki - LU, Paul - SCHAEFER, Michael K. E. - WOODRUFF, Grace - ROBINSON, Jacob - CANETE, Philip - DULIN, Jennifer N. - GEOFFROY, Cedric G. - MENZEL, Lutz - ZHENG, Binhai - COPPOLA, Giovanni - TUSZYNSKI, Mark H. Adult rat myelin enhances axonal outgrowth from neural stem cells. In SCIENCE TRANSLATIONAL MEDICINE. ISSN 1946-6234, 2018, vol. 10, no. 442, pp. HU, Neng-Wei - CORBETT, Grant T. - MOORE, Steven - KLYUBIN, Igor - O'MALLEY, Tiernan T. - WALSH, Dominic M. - LIVESEY, Frederick J. - ROWAN, Michael J. Extracellular Forms of A beta and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity. In CELL REPORTS. ISSN 2211-1247, 2018, vol. 23, no. 7, pp. 1932-1938. RAJAMANI, Uthra - GROSS, Andrew R. - HJELM, Brooke E. - SEQUEIRA, Adolfo - VAWTER, Marquis P. - TANG, Jie - GANGALAPUDI, Vineela - WANG, Yizhou - ANDRES, Allen M. - GOTTLIEB, Roberta A. - SAREEN, Dhruv. Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses. In CELL STEM CELL. ISSN 1934-5909, 2018, vol. 22, no. 5, pp. 698-+. MOHAMET, Lisa - JONES, Vicky C. - DAYANITHI, Govindan - VERKHRATSKY, Alexei. Pathological human astroglia in Alzheimer's disease: opening new horizons with stem cell technology. In FUTURE NEUROLOGY. ISSN 1479-6708, 2018, vol. 13, no. 2, pp. 87-100. WANG, Chengzhong - NAJM, Ramsey - XU, Qin - JEONG, Dah-eun - WALKER, David - BALESTRA, Maureen E. - YOON, Seo Yeon - YUAN, Heidi - LI, Gang - MILLER, Zachary A. - MILLER, Bruce L. - MALLOY, Mary J. - HUANG, Yadong. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. In NATURE MEDICINE. ISSN 1078-8956, 2018, vol. 24, no. 5, pp. 647-+. GUNHANLAR, N. - SHPAK, G. - VAN DER KROEG, M. - GOUTY-COLOMER, L. A. - MUNSHI, S. T. - LENDEMEIJER, B. - GHAZVINI, M. - DUPONT, C. - HOOGENDIJK, W. J. G. - GRIBNAU, J. - DE VRIJ, F. M. S. - KUSHNER, S. A. A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2018, vol. 23, no. 5, pp. 1336-1344. GUENNEWIG, Boris - BITAR, Maina - OBIORAH, Ifeanyi - HANKS, James - O'BRIEN, Elizabeth A. - KACZOROWSKI, Dominik C. - HURD, Yasmin L. - ROUSSOS, Panos - BRENNAND, Kristen J. - BARRY, Guy. THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders. In TRANSLATIONAL PSYCHIATRY. ISSN 2158-3188, 2018, vol. 8, no., pp. BEJOY, Julie - SONG, Liqing - ZHOU, Yi - LI, Yan. Wnt/Yes-Associated Protein Interactions During Neural Tissue Patterning of Human Induced Pluripotent Stem Cells. In TISSUE ENGINEERING PART A. ISSN 1937-3341, 2018, vol. 24, no. 7-8, pp. 546-558. ZHANG, Hongfeng - HUANG, Timothy - HONG, Yujuan - YANG, Weijie - ZHANG, Xian - LUO, Hong - XU, Huaxi - WANG, Xin. The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, 2018, vol. 10, no., pp. FANG, Yi - GAO, Ting - ZHANG, Baorong - PU, Jiali. Recent Advances: Decoding Alzheimer's Disease With Stem Cells. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, 2018, vol. 10, no., pp. YOUNG, Jessica E. - FONG, Lauren K. - FRANKOWSKI, Harald - PETSKO, Gregory A. - SMALL, Scott A. - GOLDSTEIN, Lawrence S. B. Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein. In STEM CELL REPORTS. ISSN 2213-6711, 2018, vol. 10, no. 3, pp. 1046-1058. CHANG, Chia-Yu - TING, Hsiao-Chien - SU, Hong-Lin - JENG, Jing-Ren. Combining Induced Pluripotent Stem Cells and Genome Editing Technologies for Clinical Applications. In CELL TRANSPLANTATION. ISSN 0963-6897, 2018, vol. 27, no. 3, pp. 379-392. BIRNBAUM, Julian H. - WANNER, Debora - GIETL, Anton F. - SAAKE, Antje - KUENDIG, Thomas M. - HOCK, Christoph - NITSCH, Roger M. - TACKENBERG, Christian. Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-beta and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients. In STEM CELL RESEARCH. ISSN 1873-5061, 2018, vol. 27, no., pp. 121-130. YAN, Yuanwei - SONG, Liqing - MADINYA, Jason - MA, Teng - LI, Yan. Derivation of Cortical Spheroids from Human Induced Pluripotent Stem Cells in a Suspension Bioreactor. In TISSUE ENGINEERING PART A. ISSN 1937-3341, 2018, vol. 24, no. 5-6, pp. 418-431. LI, W. - HUANG, L. - ZENG, J. - LIN, W. - LI, K. - SUN, J. - HUANG, W. - CHEN, J. - WANG, G. - KE, Q. - DUAN, J. - LAI, X. - CHEN, R. - LIU, M. - LIU, Y. - WANG, T. - YANG, X. - CHEN, Y. - XIA, H. - XIANG, A. P. Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2018, vol. 23, no. 3, pp. 499-508. ILCE, Burcu Yener - CAGIN, Umut - YILMAZER, Acelya. Cellular reprogramming: A new way to understand aging mechanisms. In WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY. ISSN 1759-7684, 2018, vol. 7, no. 2, pp. LAU, Dawn H. W. - HARTOPP, Naomi - WELSH, Natalie J. - MUELLER, Sarah - GLENNON, Elizabeth B. - MOROTZ, Gabor M. - ANNIBALI, Ambra - GOMEZ-SUAGA, Patricia - STOICA, Radu - PAILLUSSON, Sebastien - MILLER, Christopher C. J. Disruption of ER-mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis. In CELL DEATH & DISEASE. ISSN 2041-4889, 2018, vol. 9, no., pp. GHAFFARI, Layla T. - STARR, Alexander - NELSON, Andrew T. - SATTLER, Rita. Representing Diversity in the Dish: Using Patient-Derived in Vitro Models to Recreate the Heterogeneity of Neurological Disease. In FRONTIERS IN NEUROSCIENCE. ISSN 1662-453X, 2018, vol. 12, no., pp. JORFI, Mehdi - D'AVANZO, Carla - TANZI, Rudolph E. - KIM, Doo Yeon - IRIMIA, Daniel. Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease. In SCIENTIFIC REPORTS. ISSN 2045-2322, 2018, vol. 8, no., pp. ZHOU, Lujia - VERSTREKEN, Patrik. Reprogramming neurodegeneration in the big data era. In CURRENT OPINION IN NEUROBIOLOGY. ISSN 0959-4388, 2018, vol. 48, no., pp. 167-173. BOSWORTH, Allison M. - FALEY, Shannon L. - BELLAN, Leon M. - LIPPMANN, Ethan S. Modeling Neurovascular Disorders and Therapeutic Outcomes with Human-Induced Pluripotent Stem Cells. In FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. ISSN 2296-4185, 2018, vol. 5, no., pp. YE, Mengchen - LEHIGH, Kathryn M. - GINTY, David D. Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling. In ELIFE. ISSN 2050-084X, 2018, vol. 7, no., pp. AHADIAN, Samad - CIVITARESE, Robert - BANNERMAN, Dawn - MOHAMMADI, Mohammad Hossein - LU, Rick - WANG, Erika - DAVENPORT-HUYER, Locke - LAI, Ben - ZHANG, Boyang - ZHAO, Yimu - MANDLA, Serena - KOROLJ, Anastasia - RADISIC, Milica. Organ-On-A-Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies. In ADVANCED HEALTHCARE MATERIALS. ISSN 2192-2640, 2018, vol. 7, no. 2, pp. JORFI, Mehdi - D'AVANZO, Carla - KIM, Doo Yeon - IRIMIA, Daniel. Three-Dimensional Models of the Human Brain Development and Diseases. In ADVANCED HEALTHCARE MATERIALS. ISSN 2192-2640, 2018, vol. 7, no. 1, pp. JURADO, Sandra. AMPA Receptor Trafficking in Natural and Pathological Aging. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, 2018, vol. 10, no., pp. CORREA-VELLOSO, Juliana C. - GONCALVES, Maria C. B. - NAALDIJK, Yahaira - OLIVEIRA-GIACOMELLI, Agatha - PILLAT, Micheli M. - ULRICH, Henning. Pathophysiology in the comorbidity of Bipolar Disorder and Alzheimer's Disease: pharmacological and stem cell approaches. In PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. ISSN 0278-5846, 2018, vol. 80, no., pp. 34-53. KAVYASUDHA, Chavali - MACRIN, Dannie - ARULJOTHI, K. N. - JOSEPH, Joel P. - HARISHANKAR, M. K. - DEVI, Arikketh. Clinical Applications of Induced Pluripotent Stem Cells Stato Attuale. In CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 1: STEM CELLS IN REGENERATIVE MEDICINE: ADVANCES AND CHALLENGES. ISSN 0065-2598, 2018, vol. 1079, no., pp. 127-149. MERTENS, Jerome - REID, Dylan - LAU, Shong - KIM, Yongsung - GAGE, Fred H. Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases. In ANNUAL REVIEW OF GENETICS, VOL 52. ISSN 0066-4197, 2018, vol. 52, no., pp. 271-293. LEMCHE, Erwin. Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review. In CURRENT GENOMICS. ISSN 1389-2029, 2018, vol. 19, no. 7, pp. 522-602. MA, Tian-Jun - GAO, Jie - LIU, Yan - ZHUANG, Jian-Hua - YIN, Chuan - LI, Peng - MAO, Lei - XU, Jin - XU, Yi-Xin - LI, Yan-Peng - ZHAO, Zhong-Xin - YIN, You. Nanomedicine Strategies for Sustained, Controlled and Targeted Treatment of Alzheimer's Disease. In MINI-REVIEWS IN MEDICINAL CHEMISTRY. ISSN 1389-5575, 2018, vol. 18, no. 12, pp. 1035-1046. KUMAR, Satish - BLANGERO, John - CURRAN, Joanne E. Induced Pluripotent Stem Cells in Disease Modeling and Gene Identification. In DISEASE GENE IDENTIFICATION: METHODS AND PROTOCOLS, 2ND EDITION. ISSN 1064-3745, 2018, vol. 1706, no., pp. 17-38. KWAK, Kyeong-Ah - LEE, Seung-Pyo - YANG, Jin-Young - PARK, Young-Seok. Current Perspectives regarding Stem Cell-Based Therapy for Alzheimer's Disease. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2018, vol., no., pp. GIAU, Vo Van - LEE, Hyon - SHIM, Kyu Hwan - BAGYINSZKY, Eva - AN, Seong Soo A. Genome-editing applications of CRISPR-Cas9 to promote in vitro studies of Alzheimer's disease. In CLINICAL INTERVENTIONS IN AGING. ISSN 1178-1998, 2018, vol. 13, no., pp. 221-233. COLACURCIO, Daniel J. - PENSALFINI, Anna - JIANG, Ying - NIXON, Ralph A. Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease. In FREE RADICAL BIOLOGY AND MEDICINE. ISSN 0891-5849, 2018, vol. 114, no., pp. 40-51. KARAGIANNIS, Peter - TAKAHASHI, Kazutoshi - SAITO, Megumu - YOSHIDA, Yoshinori - OKITA, Keisuke - WATANABE, Akira - INOUE, Haruhisa - YAMASHITA, Jun K. - TODANI, Masaya - NAKAGAWA, Masato - OSAWA, Mitsujiro - YASHIRO, Yoshimi - YAMANAKA, Shinya - OSAFUNE, Kenji. INDUCED PLURIPOTENT STEM CELLS AND THEIR USE IN HUMAN MODELS OF DISEASE AND DEVELOPMENT. In PHYSIOLOGICAL REVIEWS. ISSN 0031-9333, 2019, vol. 99, no. 1, pp. 79-114. MAHMOUDI, Salah - XU, Lucy - BRUNET, Anne. Turning back time with emerging rejuvenation strategies. In NATURE CELL BIOLOGY. ISSN 1465-7392, 2019, vol. 21, no. 1, pp. 32-43. LIN, Haishuang - LI, Qiang - DU, Qian - WANG, Ou - WANG, Zhanqi - AKERT, Leonard - CARLSON, Mark A. - ZHANG, Chi - SUBRAMANIAN, Anuradha - ZHANG, Chi - LUNNING, Matthew - LI, Ming - LEI, Yuguo. Integrated generation of induced pluripotent stem cells in a low-cost device. In BIOMATERIALS. ISSN 0142-9612, 2019, vol. 189, no., pp. 23-36. HOES, Martijn F. - BOMER, Nils - VAN DER MEER, Peter. Concise Review: The Current State of Human In Vitro Cardiac Disease Modeling: A Focus on Gene Editing and Tissue Engineering. In STEM CELLS TRANSLATIONAL MEDICINE. ISSN 2157-6564, 2019, vol. 8, no. 1, pp. 66-74. FOVEAU, Benedicte - CORREIA, Ana Sofia - HEBERT, Sebastien S. - RAINONE, Sara - POTVIN, Olivier - KERGOAT, Marie-Jeanne - BELLEVILLE, Sylvie - DUCHESNE, Simon - LEBLANC, Andrea C. Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 67, no. 3, pp. 893-910. WINSTON, Charisse N. - AULSTON, Brent - ROCKENSTEIN, Edward M. - ADAME, Anthony - PRIKHODKO, Olga - DAVE, Kishan N. - MISHRA, Priyanka - RISSMAN, Robert A. - YUAN, Shauna H. Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 67, no. 2, pp. 541-553. WU, Yi-Ying - CHIU, Feng-Lan - YEH, Chan-Shien - KUO, Hung-Chih. Opportunities and challenges for the use of induced pluripotent stem cells in modelling neurodegenerative disease. In OPEN BIOLOGY. ISSN 2046-2441, 2019, vol. 9, no. 1, pp. QIU, Qiongqiong - SHEN, Luxi - JIA, Longfei - WANG, Qi - LI, Fangyu - LI, Ying - JIA, Jianping. A Novel PSEN1 M139L Mutation Found in a Chinese Pedigree with Early-Onset Alzheimer's Disease Increases A beta(42)/A beta(40) ratio. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 69, no. 1, pp. 199-212. LEWIS, Patrick A. - SPILLANE, Jennifer E. ALZHEIMER'S DISEASE AND DEMENTIA. In MOLECULAR AND CLINICAL PATHOLOGY OF NEURODEGENERATIVE DISEASE, 2019, vol., no., pp. 25-82. STODDARD-BENNETT, Theo - PERA, Renee Reijo. Treatment of Parkinson's Disease through Personalized Medicine and Induced Pluripotent Stem Cells. In CELLS, 2019, vol. 8, no. 1, pp. EASLEY, Charles A. Induced Pluripotent Stem Cells (iPSCs) in Developmental Toxicology. In DEVELOPMENTAL TOXICOLOGY: METHODS AND PROTOCOLS, 2ND EDITION. ISSN 1064-3745, 2019, vol. 1965, no., pp. 19-34. LO GIUDICE, Maria - MIHALIK, Balazs - TURI, Zsofia - DINNYES, Andras - KOBOLAK, Julianna. Calcilytic NPS 2143 Reduces Amyloid Secretion and Increases sA beta PP alpha Release from PSEN1 Mutant iPSC-Derived Neurons. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 72, no. 3, pp. 885-899. AULSTON, Brent - LIU, Qing - MANTE, Michael - FLORIO, Jazmin - RISSMAN, Robert A. - YUAN, Shauna H. Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2019, vol. 72, no. 2, pp. 575-585. DANTER, Wayne R. DeepNEU: cellular reprogramming comes of age a machine learning platform with application to rare diseases research. In ORPHANET JOURNAL OF RARE DISEASES. ISSN 1750-1172, 2019, vol. 14, no., pp. PHILLIPS, Jack K. - SHERMAN, Sydney A. - COTTON, Kristen Y. - HEDDLESTON, John M. - TAYLOR, Aaron B. - FINAN, John D. Characterization of neurite dystrophy after trauma by high speed structured illumination microscopy and lattice light sheet microscopy. In JOURNAL OF NEUROSCIENCE METHODS. ISSN 0165-0270, 2019, vol. 312, no., pp. 154-161. PAONESSA, Francesco - EVANS, Lewis D. - SOLANKI, Ravi - LARRIEU, Delphine - WRAY, Selina - HARDY, John - JACKSON, Stephen P. - LIVESEY, Frederick J. Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia. In CELL REPORTS. ISSN 2211-1247, 2019, vol. 26, no. 3, pp. 582-+. MEYER, Katharina - FELDMAN, Heather M. - LU, Tao - DRAKE, Derek - LIM, Elaine T. - LING, King-Hwa - BISHOP, Nicholas A. - PAN, Ying - SEO, Jinsoo - LIN, Yuan-Ta - SU, Susan C. - CHURCH, George M. - TSAI, Li-Huei - YANKNER, Bruce A. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. In CELL REPORTS. ISSN 2211-1247, 2019, vol. 26, no. 5, pp. 1112-+. EGLEN, Richard M. - REISINE, Terry. Human iPS Cell-Derived Patient Tissues and 3D Cell Culture Part 1: Target Identification and Lead Optimization. In SLAS TECHNOLOGY. ISSN 2472-6303, 2019, vol. 24, no. 1, pp. 3-17. ZIFF, Oliver J. - PATANI, Rickie. Harnessing cellular aging in human stem cell models of amyotrophic lateral sclerosis. In AGING CELL. ISSN 1474-9726, 2019, vol. 18, no. 1, pp. MITRA, Sumonto - BEHBAHANI, Homira - ERIKSDOTTER, Maria. Innovative Therapy for Alzheimer's Disease-With Focus on Biodelivery of NGF. In FRONTIERS IN NEUROSCIENCE. ISSN 1662-453X, 2019, vol. 13, no., pp. MAJOLO, Fernanda - MARINOWIC, Daniel Rodrigo - MACHADO, Denise Cantarelli - DA COSTA, Jaderson Costa. Important advances in Alzheimer's disease from the use of induced pluripotent stem cells. In JOURNAL OF BIOMEDICAL SCIENCE. ISSN 1021-7770, 2019, vol. 26, no., pp. DUBEY, Sunil Kumar - RAM, Munnangi Siva - KRISHNA, Kowthavarapu Venkata - SAHA, Ranendra Narayan - SINGHVI, Gautam - AGRAWAL, Mukta - AJAZUDDIN - SARAF, Swarnlata - SARAF, Shailendra - ALEXANDER, Amit. Recent Expansions on Cellular Models to Uncover the Scientific Barriers Towards Drug Development for Alzheimer's Disease. In CELLULAR AND MOLECULAR NEUROBIOLOGY. ISSN 0272-4340, 2019, vol. 39, no. 2, pp. 181-209. VAN DER KANT, Rik - LANGNESS, Vanessa F. - HERRERA, Cheryl M. - WILLIAMS, Daniel A. - FONG, Lauren K. - LEESTEMAKER, Yves - STEENVOORDEN, Evelyne - RYNEARSON, Kevin D. - BROUWERS, Jos F. - HELMS, J. Bernd - OVAA, Huib - GIERA, Martin - WAGNER, Steven L. - BANG, Anne G. - GOLDSTEIN, Lawrence S. B. Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-beta in iPSC-Derived Alzheimer's Disease Neurons. In CELL STEM CELL. ISSN 1934-5909, 2019, vol. 24, no. 3, pp. 363-+. BLANCHARD, Joel W. - TSAI, Li-Huei. Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer's Disease. In CELL STEM CELL. ISSN 1934-5909, 2019, vol. 24, no. 3, pp. 347-349. HUANG, Guanqun - CHEN, Shuting - CHEN, Xiaoxia - ZHENG, Jiajun - XU, Zhuoran - TORSHIZI, Abolfazl Doostparast - GONG, Siyi - CHEN, Qingpei - MA, Xiaokuang - YU, Jiandong - ZHOU, Libing - QIU, Shenfeng - WANG, Kai - SHI, Lingling. Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons. In FRONTIERS IN NEUROANATOMY. ISSN 1662-5129, 2019, vol. 13, no., pp. YAN, Yuanwei - BEJOY, Julie - MARZANO, Mark - LI, Yan. The Use of Pluripotent Stem Cell-Derived Organoids to Study Extracellular Matrix Development during Neural Degeneration. In CELLS, 2019, vol. 8, no. 3, pp. PERHOC, Ana Babic - BARILAR, Jelena Osmanovic - KNEZOVIC, Ana - FARKAS, Vladimir - BAGARIC, Robert - SVARC, Alfred - GRUNBLATT, Edna - RIEDERER, Peter - SALKOVIC-PETRISIC, Melita. Cognitive, behavioral and metabolic effects of oral galactose treatment in the transgenic Tg2576 mice. In NEUROPHARMACOLOGY. ISSN 0028-3908, 2019, vol. 148, no., pp. 50-67. KUMAR, Sundramurthy - KARTHIKEYAN, Narayanan - MISHRA, Sachin - PADMANABHAN, Parasuraman - RADDA, George - GULYAS, Balazs. Misfolded Protein Linked Strategies Toward Biomarker Development for Neurodegenerative Diseases. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, 2019, vol. 56, no. 4, pp. 2559-2578. JULIA, T. C. W. Human iPSC application in Alzheimer's disease and Tau-related neurodegenerative diseases. In NEUROSCIENCE LETTERS. ISSN 0304-3940, 2019, vol. 699, no., pp. 31-40. WADHWANI, Anil R. - AFFANEH, Amira - VAN GULDEN, Stephanie - KESSLER, John A. Neuronal apolipoprotein E4 increases cell death and phosphorylated tau release in alzheimer disease. In ANNALS OF NEUROLOGY. ISSN 0364-5134, 2019, vol. 85, no. 5, pp. 726-739. MOYSIDOU, E. - GOULIELMAKI, M. - CHRISTODOULOU, I - ZOUMPOURLIS, V. Induced pluripotent stem cells: Cell therapy in regenerative medicine and modeling of human disease. In ARCHIVES OF HELLENIC MEDICINE. ISSN 1105-3992, 2019, vol. 36, no. 3, pp. 300-311. XIA, Weiming. gamma-Secretase and its modulators: Twenty years and beyond. In NEUROSCIENCE LETTERS. ISSN 0304-3940, 2019, vol. 701, no., pp. 162-169. PAPARIELLO, Alexis - NEWELL-LITWA, Karen. Human-Derived Brain Models: Windows Into Neuropsychiatric Disorders and Drug Therapies. In ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES. ISSN 1540-658X, 2019, vol., no., pp. PORTERFIELD, Veronica. Neural Progenitor Cell Derivation Methodologies for Drug Discovery Applications. In ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES. ISSN 1540-658X, 2019, vol., no., pp. CHONG, Cheong-Meng - SU, Huanxing - LU, Jin-Jian - WANG, Yitao. The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer's disease. In CHINESE MEDICINE. ISSN 1749-8546, 2019, vol. 14, no., pp. HAWKINS, Kate Elizabeth - DUCHEN, Michael. 'Modelling mitochondrial dysfunction in Alzheimer's disease using human induced pluripotent stem cells. In WORLD JOURNAL OF STEM CELLS. ISSN 1948-0210, 2019, vol. 11, no. 5, pp. 236-253. CHANG, Kuo-Hsuan - LEE-CHEN, Guey-Jen - HUANG, Ching-Chang - LIN, Jia-Li - CHEN, Yi-Jing - WEI, Pei-Chi - LO, Yen-Shi - YAO, Chin-Fa - KUO, Ming-Wei - CHEN, Chiung-Mei. Modeling Alzheimer's Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation. In MOLECULAR NEUROBIOLOGY. ISSN 0893-7648, 2019, vol. 56, no. 6, pp. 3972-3983. ANTONIO GARCIA-LEON, Juan - VITORICA, Javier - GUTIERREZ, Antonia. Use of human pluripotent stem cell-derived cells for neurodegenerative disease modeling and drug screening platform. In FUTURE MEDICINAL CHEMISTRY. ISSN 1756-8919, 2019, vol. 11, no. 11, pp. 1305-1322. CHUKWURAH, Evelyn - OSMUNDSEN, Allison - DAVIS, Shannon W. - LIZARRAGA, Sofia B. All Together Now: Modeling the Interaction of Neural With Non-neura Systems Using Organoid Models. In FRONTIERS IN NEUROSCIENCE. ISSN 1662-453X, 2019, vol. 13, no., pp. CASTRO, Manuel A. - HADZISELIMOVIC, Arina - SANDERS, Charles R. The vexing complexity of the amyloidogenic pathway. In PROTEIN SCIENCE. ISSN 0961-8368, 2019, vol. 28, no. 7, pp. 1177-1193. KHASPEKOV, L. G. Modeling of Alzheimer's Disease and Outlooks for its Therapy Using Induced Pluripotent Stem Cells. In NEUROCHEMICAL JOURNAL. ISSN 1819-7124, 2019, vol. 13, no. 3, pp. 215-228. DE LEEUW, Sherida - TACKENBERG, Christian. Alzheimer's in a dish induced pluripotent stem cell-based disease modeling. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, 2019, vol. 8, no., pp. POVERO, Davide - PINATEL, Eva M. - LESZCZYNSKA, Aleksandra - LOYAL, Nidhi P. - NISHIO, Takahiro - KIM, Jihoon - KNEIBER, David - HORCEL, Lucas de Araujo - EGUCHI, Akiko - ORDONEZ, Paulina M. - KISSELEVA, Tatiana - FELDSTEIN, Ariel E. Human induced pluripotent stem cell-derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis. In JCI INSIGHT, 2019, vol. 4, no. 14, pp. SONG, Liqing - YUAN, Xuegang - JONES, Zachary - VIED, Cynthia - MIAO, Yu - MARZANO, Mark - HUA, Thien - SANG, Qing-Xiang Amy - GUAN, Jingjiao - MA, Teng - ZHOU, Yi - LI, Yan. Functionalization of Brain Region-specific Spheroids with Isogenic Microglia-like Cells. In SCIENTIFIC REPORTS. ISSN 2045-2322, 2019, vol. 9, no., pp. CHAKARI-KHIAVI, Forough - DOLATI, Sanam - CHAKARI-KHIAVI, Aref - ABBASZADEH, Hossein - AGHEBATI-MALEKI, Leili - POURLAK, Tannaz - MEHDIZADEH, Amir - YOUSEFI, Mehdi. Prospects for the application of mesenchymal stem cells in Alzheimer's disease treatment. In LIFE SCIENCES. ISSN 0024-3205, 2019, vol. 231, no., pp. FERNANDEZ-SUSAVILA, Hector - BUGALLO-CASAL, Ana - CASTILLO, Jose - CAMPOS, Francisco. Adult Stem Cells and Induced Pluripotent Stem Cells for Stroke Treatment. In FRONTIERS IN NEUROLOGY. ISSN 1664-2295, 2019, vol. 10, no., pp. VAN DEN HURK, Mark - BARDY, Cedric. Single-cell multimodal transcriptomics to study neuronal diversity in human stem cell-derived brain tissue and organoid models. In JOURNAL OF NEUROSCIENCE METHODS. ISSN 0165-0270, 2019, vol. 325, no., pp. CHANG, Eun-Ah - JIN, Sung-Won - NAM, Myung-Hyun - KIM, Sang-Dae. Human Induced Pluripotent Stem Cells : Clinical Significance and Applications in Neurologic Diseases. In JOURNAL OF KOREAN NEUROSURGICAL SOCIETY. ISSN 2005-3711, 2019, vol. 62, no. 5, pp. 493-501. MARZANO, Mark - BEJOY, Julie - CHEERATHODI, Mujeeb R. - SUN, Li - YORK, Sara B. - ZHAO, Jing - KANEKIYO, Takahisa - BU, Guojun - MECKES, David G. - LI, Yan. Differential Effects of Extracellular Vesicles of Lineage-Specific Human Pluripotent Stem Cells on the Cellular Behaviors of Isogenic Cortical Spheroids. In CELLS, 2019, vol. 8, no. 9, pp. UBINA, Teresa - MAGALLANES, Martha - SRIVASTAVA, Saumya - WARDEN, Charles D. - YEE, Jiing-Kuan - SALVATERRA, Paul M. A Human Embryonic Stem Cell Model of A beta-Dependent Chronic Progressive Neurodegeneration. In FRONTIERS IN NEUROSCIENCE, 2019, vol. 13, no., pp. GUIX, Francesc X. The interplay between aging-associated loss of protein homeostasis and extracellular vesicles in neurodegeneration. In JOURNAL OF NEUROSCIENCE RESEARCH. ISSN 0360-4012, 2019, vol., no., pp. ESSAYAN-PEREZ, Sofia - ZHOU, Bo - NABET, Amber M. - WERNIG, Marius - HUANG, Yu-Wen Alvin. Modeling Alzheimer's disease with human iPS cells: advancements, lessons, and applications. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, 2019, vol. 130, no., pp. ZHANG, Yuehou - HU, Wenzhi - MA, Kui - ZHANG, Cuiping - FU, Xiaobing. Reprogramming of Keratinocytes as Donor or Target Cells Holds Great Promise for Cell Therapy and Regenerative Medicine. In STEM CELL REVIEWS AND REPORTS. ISSN 2629-3269, 2019, vol. 15, no. 5, pp. 680-689. KWART, Dylan - GREGG, Andrew - SCHECKEL, Claudia - MURPHY, Elisabeth - PAQUET, Dominik - DUFFIELD, Michael - FAK, John - OLSEN, Olav - DARNELL, Robert - TESSIER-LAVIGNE, Marc. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP beta-CTFs, Not A beta. In NEURON. ISSN 0896-6273, 2019, vol. 104, no. 2, pp. 256-+. TRAXLER, Larissa - EDENHOFER, Frank - MERTENS, Jerome. Next-generation disease modeling with direct conversion: a new path to old neurons. In FEBS LETTERS. ISSN 0014-5793, 2019, vol., no., pp. CANDELARIO, Kate M. - BALAJ, Leonora - ZHENG, Tong - SKOG, Johan - SCHEFFLER, Bjorn - BREAKEFIELD, Xandra - SCHULE, Birgitt - STEINDLER, Dennis A. Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cells. In JOURNAL OF COMPARATIVE NEUROLOGY. ISSN 0021-9967, 2019, vol., no., pp. OLIVEIRA, Barbara - YAHYA, Aysan Cerag - NOVARINO, Gaia. Modeling cell-cell interactions in the brain using cerebral organoids. In BRAIN RESEARCH. ISSN 0006-8993, 2019, vol. 1724, no., pp. LI, Yuan - SUN, Xueying - LIU, Houfu - HUANG, Liang - MENG, Guofeng - DING, Yu - SU, Wenji - LU, Jiaqi - GONG, Sophie - TERSTAPPEN, Georg C. - ZHANG, Ru - ZHANG, Wandong. Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs. In NEUROSCIENCE BULLETIN. ISSN 1673-7067, 2019, vol. 35, no. 6, pp. 996-1010. ZHOU, Yuanshuai - XU, Zhongjuan - YU, Yanzhen - CAO, Junjun - QIAO, Yong - QIAO, Hong - SUO, Guangli. Comprehensive analysis of the lncRNA-associated ceRNA network identifies neuroinflammation biomarkers for Alzheimer's disease. In MOLECULAR OMICS, 2019, vol. 15, no. 6, pp. 459-469. NAPHADE, Swati - TSHILENGE, Kizito-Tshitoko - ELLERBY, Lisa M. Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells. In NEUROTHERAPEUTICS. ISSN 1933-7213, 2019, vol., no., pp. AMIN, Nashwa - TAN, Xiaoning - REN, Qiannan - ZHU, Ning - BOTCHWAY, Benson O. A. - HU, Zhiying - FANG, Marong. Recent advances of induced pluripotent stem cells application in neurodegenerative diseases. In PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. ISSN 0278-5846, 2019, vol. 95, no., pp. VAN DER KANT, Rik - GOLDSTEIN, Lawrence S. B. - OSSENKOPPELE, Rik. Amyloid-beta-independent regulators of tau pathology in Alzheimer disease. In NATURE REVIEWS NEUROSCIENCE. ISSN 1471-003X, 2020, vol. 21, no. 1, pp. 21-35. PENNEY, Jay - RALVENIUS, William T. - TSAI, Li-Huei. Modeling Alzheimer's disease with iPSC-derived brain cells. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2020, vol. 25, no. 1, pp. 148-167. LIU, Yanying - WANG, Hongmin. Modeling Sporadic Alzheimer's Disease by Efficient Direct Reprogramming of the Elderly Derived Disease Dermal Fibroblasts into Neural Stem Cells. In JOURNAL OF ALZHEIMERS DISEASE. ISSN 1387-2877, 2020, vol. 73, no. 3, pp. 919-933. HAN, Fabin - BI, Jianzhong - QIAO, Liyan - ARANCIO, Ottavio. Stem Cell Therapy for Alzheimer's Disease. In STEM CELL-BASED THERAPY FOR NEURODEGENERATIVE DISEASES. ISSN 0065-2598, 2020, vol. 1266, no., pp. 39-55. ROMANAZZO, Sara - LIN, Kang - SRIVASTAVA, Pallavi - KILIAN, Kristopher A. Targeting cell plasticity for regeneration: From in vitro to in vivo reprogramming. In ADVANCED DRUG DELIVERY REVIEWS. ISSN 0169-409X, 2020, vol. 161, no., pp. 124-144. BOTTE, Alexandra - POTIER, Marie-Claude. Focusing on cellular biomarkers: The endo-lysosomal pathway in Down syndrome. In PRECLINICAL RESEARCH IN DOWN SYNDROME: INSIGHTS FOR PATHOPHYSIOLOGY AND TREATMENTS. ISSN 0079-6123, 2020, vol. 251, no., pp. 209-243. FARAVELLI, I. - COSTAMAGNA, G. - TAMANINI, S. - CORTI, S. Back to the origins: Human brain organoids to investigate neurodegeneration. In BRAIN RESEARCH. ISSN 0006-8993, 2020, vol. 1727, no., pp. CIFELLI, Jessica L. - BERG, Kyle R. - YANG, Jerry. Benzothiazole amphiphiles promote RasGRF1-associated dendritic spine formation in human stem cell-derived neurons. In FEBS OPEN BIO. ISSN 2211-5463, 2020, vol. 10, no. 3, pp. 386-395. AMATO, Paula - DAAR, Judith - FRANCIS, Leslie - KLIPSTEIN, Sigal - BALL, David - RINAUDO, Paolo - RAJOVIC, Alexandar - PALMORE, Marissa - TIPTON, Sean - COUTIFARIS, Christos - REINDOLLAR, Richard - GITLIN, Susan - COLLINS, Lee - DAVIS, Joseph - DAVIS, Owen - GATES, Elena - GINSBURG, Elizabeth - MCCULLOUGH, Laurence - PAULSON, Richard - RYAN, Ginny - SAUER, Mark - WESTPHAL, Lynn - ZWEIFEL, Julianne. Ethics in embryo research: a position statement by the ASRM Ethics in Embryo Research Task Force and the ASRM Ethics Committee. In FERTILITY AND STERILITY. ISSN 0015-0282, 2020, vol. 113, no. 2, pp. 270-294. ZHANG, Fu-Qiang - JIANG, Jin-Lan - ZHANG, Jing-Tian - NIU, Han - FU, Xue-Qi - ZENG, Lin-Lin. Current status and future prospects of stem cell therapy in Alzheimer's disease. In NEURAL REGENERATION RESEARCH. ISSN 1673-5374, 2020, vol. 15, no. 2, pp. 242-250. WEI WULI - TSAI, Sheng-Tzung - CHIOU, Tzyy-Wen - HARN, Horng-Jyh. Human-Induced Pluripotent Stem Cells and Herbal Small-Molecule Drugs for Treatment of Alzheimer's Disease. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, vol. 21, no. 4, pp. ROULEAU, Nicolas - CANTLEY, William L. - LIAUDANSKAYA, Volha - BERK, Alexander - DU, Chuang - RUSK, William - PEIRENT, Emily - KOESTER, Cole - NIELAND, Thomas J. F. - KAPLAN, David L. A Long-Living Bioengineered Neural Tissue Platform to Study Neurodegeneration. In MACROMOLECULAR BIOSCIENCE. ISSN 1616-5187, 2020, vol. 20, no. 3, pp. SIMS, Rebecca - HILL, Matthew - WILLIAMS, Julie. The multiplex model of the genetics of Alzheimer's disease. In NATURE NEUROSCIENCE. ISSN 1097-6256, 2020, vol. 23, no. 3, pp. 311-322. ARGENTATI, Chiara - TORTORELLA, Ilaria - BAZZUCCHI, Martina - MORENA, Francesco - MARTINO, Sabata. Harnessing the Potential of Stem Cells for Disease Modeling: Progress and Promises. In JOURNAL OF PERSONALIZED MEDICINE, 2020, vol. 10, no. 1, pp. CAVALLI, Eugenio - BATTAGLIA, Giuseppe - BASILE, Maria Sofia - BRUNO, Valeria - PETRALIA, Maria Cristina - LOMBARDO, Salvo Danilo - PENNISI, Manuela - KALFIN, Reni - TANCHEVA, Lyubka - FAGONE, Paolo - NICOLETTI, Ferdinando - MANGANO, Katia. Exploratory Analysis of iPSCS-Derived Neuronal Cells as Predictors of Diagnosis and Treatment of Alzheimer Disease. In BRAIN SCIENCES, 2020, vol. 10, no. 3, pp. CASAMASSA, Alessia - FERRARI, Daniela - GELATI, Maurizio - CARELLA, Massimo - VESCOVI, Angelo Luigi - ROSATI, Jessica. A Link between Genetic Disorders and Cellular Impairment, Using Human Induced Pluripotent Stem Cells to Reveal the Functional Consequences of Copy Number Variations in the Central Nervous System-A Close Look at Chromosome 15. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, vol. 21, no. 5, pp. TOMASKOVIC-CROOK, Eva - GU, Qi - RAHIM, Siti N. Abdul - WALLACE, Gordon G. - CROOK, Jeremy M. Conducting Polymer Mediated Electrical Stimulation Induces Multilineage Differentiation with Robust Neuronal Fate Determination of Human Induced Pluripotent Stem Cells. In CELLS, 2020, vol. 9, no. 3, pp. SHARMA, Arun - SANCES, Samuel - WORKMAN, Michael J. - SVENDSEN, Clive N. Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery. In CELL STEM CELL. ISSN 1934-5909, 2020, vol. 26, no. 3, pp. 309-329. KWAK, Sang Su - WASHICOSKY, Kevin J. - BRAND, Emma - VON MAYDELL, Djuna - ARONSON, Jenna - KIM, Susan - CAPEN, Diane E. - CETINBAS, Murat - SADREYEV, Ruslan - NING, Shen - BYLYKBASHI, Enjana - XIA, Weiming - WAGNER, Steven L. - CHOI, Se Hoon - TANZI, Rudolph E. - KIM, Doo Yeon. Amyloid-beta 42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer's disease. In NATURE COMMUNICATIONS. ISSN 2041-1723, 2020, vol. 11, no. 1, pp. D'SOUZA, Gary X. - ROSE, Shannon E. - KNUPP, Allison - NICHOLSON, Daniel A. - KEENE, Christopher Dirk - YOUNG, Jessica E. The application ofin vitro-derived human neurons in neurodegenerative disease modeling. In JOURNAL OF NEUROSCIENCE RESEARCH. ISSN 0360-4012, 2021, vol. 99, no. 1, pp. 124-140. BINDER, Jessica L. - CHANDER, Praveen - DERETIC, Vojo - WEICK, Jason P. - BHASKAR, Kiran. Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons. In PLOS ONE. ISSN 1932-6203, 2020, vol. 15, no. 3, pp. LI, Ling - KIM, Hee Jin - ROH, Jee Hoon - KIM, Minchul - KOH, Wonyoung - KIM, Younghoon - HEO, Hyohoon - CHUNG, Jaehoon - NAKANISHI, Mahito - YOON, Taeyoung - HONG, Chang Pyo - SEO, Sang Won - NA, Duk L. - SONG, Jihwan. Pathological manifestation of the induced pluripotent stem cell-derived cortical neurons from an early-onset Alzheimer's disease patient carrying a presenilin-1 mutation (S170F). In CELL PROLIFERATION. ISSN 0960-7722, 2020, vol. 53, no. 4, pp. PAPASPYROPOULOS, Angelos - TSOLAKI, Magdalini - FOROGLOU, Nicolas - PANTAZAKI, Anastasia A. Modeling and Targeting Alzheimer's Disease With Organoids. In FRONTIERS IN PHARMACOLOGY. ISSN 1663-9812, 2020, vol. 11, no., pp. ZHANG, Xinwen - HU, Di - SHANG, Yutong - QI, Xin. Using induced pluripotent stem cell neuronal models to study neurodegenerative diseases. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, 2020, vol. 1866, no. 4, pp. PAGE, Shyanne - PATEL, Ronak - RAUT, Snehal - AL-AHMAD, Abraham. Neurological diseases at the blood-brain barrier: Stemming new scientific paradigms using patient-derived induced pluripotent cells. In BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. ISSN 0925-4439, 2020, vol. 1866, no. 4, pp. KLIMMT, Julien - DANNERT, Angelika - PAQUET, Dominik. Neurodegeneration in a dish: advancing human stem-cell-based models of Alzheimer's disease. In CURRENT OPINION IN NEUROBIOLOGY. ISSN 0959-4388, 2020, vol. 61, no., pp. 96-104. CHANG, Chia-Yu - TING, Hsiao-Chien - LIU, Ching-Ann - SU, Hong-Lin - CHIOU, Tzyy-Wen - LIN, Shinn-Zong - HARN, Horng-Jyh - HO, Tsung-Jung. Review Induced Pluripotent Stem Cell (iPSC)-Based Neurodegenerative Disease Models for Phenotype Recapitulation and Drug Screening. In MOLECULES, 2020, vol. 25, no. 8, pp. BERA, Sujoy - CAMBLOR-PERUJO, Santiago - CALLEJA BARCA, Elena - NEGRETE-HURTADO, Albert - RACHO, Julia - DE BRUYCKERE, Elodie - WITTICH, Christoph - ELLRICH, Nina - MARTINS, Soraia - ADJAYE, James - KONONENKO, Natalia L. AP-2 reduces amyloidogenesis by promoting BACE1 trafficking and degradation in neurons. In EMBO REPORTS. ISSN 1469-221X, 2020, vol. 21, no. 6, pp. TRAN, Jenne - ANASTACIO, Helena - BARDY, Cedric. Genetic predispositions of Parkinson's disease revealed in patient-derived brain cells. In NPJ PARKINSONS DISEASE, 2020, vol. 6, no. 1, pp. RAMAN, Sreedevi - BROOKHOUSER, Nicholas - BRAFMAN, David A. Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, 2020, vol. 138, no., pp. XU, Shisan - ZHANG, Huan - PAO, Ping-Chieh - LEE, Audrey - WANG, Jun - CHAN, Yu Suen - MANNO, Francis A. M. - CHAN, Shun Wan - CHENG, Shuk Han - CHEN, Xueping. Exposure to phthalates impaired neurodevelopment through estrogenic effects and induced DNA damage in neurons. In AQUATIC TOXICOLOGY. ISSN 0166-445X, 2020, vol. 222, no., pp. WANG, Yong - LIANG, Ge - LIANG, Shuqing - MUND, Rachel - SHI, Yun - WEI, Huafeng. Dantrolene Ameliorates Impaired Neurogenesis and Synaptogenesis in Induced Pluripotent Stem Cell Lines Derived from Patients with Alzheimer's Disease. In ANESTHESIOLOGY. ISSN 0003-3022, 2020, vol. 132, no. 5, pp. 1062-1079. LOGAN, Sarah - ARZUA, Thiago - YAN, Yasheng - JIANG, Congshan - LIU, Xiaojie - YU, Lai-Kang - LIU, Qing-Song - BAI, Xiaowen. Dynamic Characterization of Structural, Molecular, and Electrophysiological Phenotypes of Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids, and Comparison with Fetal and Adult Gene Profiles. In CELLS, 2020, vol. 9, no. 5, pp. SLANZI, Anna - IANNOTO, Giulia - ROSSI, Barbara - ZENARO, Elena - CONSTANTIN, Gabriela. In vitro Models of Neurodegenerative Diseases. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, 2020, vol. 8, no., pp. CHEN, Shi-Dong - LI, Hong-Qi - CUI, Mei - DONG, Qiang - YU, Jin-Tai. Pluripotent stem cells for neurodegenerative disease modeling: an expert view on their value to drug discovery. In EXPERT OPINION ON DRUG DISCOVERY. ISSN 1746-0441, 2020, vol. 15, no. 9, pp. 1081-1094. GHATAK, Swagata - DOLATABADI, Nima - GAO, Richard - WU, Yin - SCOTT, Henry - TRUDLER, Dorit - SULTAN, Abdullah - AMBASUDHAN, Rajesh - NAKAMURA, Tomohiro - MASLIAH, Eliezer - TALANTOVA, Maria - VOYTEK, Bradley - LIPTON, Stuart A. NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2020, vol., no., pp. VADODARIA, Krishna C. - JONES, Jeffrey R. - LINKER, Sara - GAGE, Fred H. Modeling Brain Disorders Using Induced Pluripotent Stem Cells. In COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. ISSN 1943-0264, 2020, vol. 12, no. 6, pp. KNUPP, Allison - MISHRA, Swati - MARTINEZ, Refugio - BRAGGIN, Jacquelyn E. - SZABO, Marcell - KINOSHITA, Chizuru - HAILEY, Dale W. - SMALL, Scott A. - JAYADEV, Suman - YOUNG, Jessica E. Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing. In CELL REPORTS. ISSN 2211-1247, 2020, vol. 31, no. 9, pp. FRANCISTIOVA, Linda - BIANCHI, Carolina - DI LAURO, Caterina - SEBASTIAN-SERRANO, Alvaro - DE DIEGO-GARCIA, Laura - KOBOLAK, Julianna - DINNYES, Andras - DIAZ-HERNANDEZ, Miguel. The Role of P2X7 Receptor in Alzheimer's Disease. In FRONTIERS IN MOLECULAR NEUROSCIENCE. ISSN 1662-5099, 2020, vol. 13, no., pp. BLANCHARD, Joel W. - BULA, Michael - DAVILA-VELDERRAIN, Jose - AKAY, Leyla Anne - ZHU, Lena - FRANK, Alexander - VICTOR, Matheus B. - BONNER, Julia Maeve - MATHYS, Hansruedi - LIN, Yuan-Ta - KO, Tak - BENNETT, David A. - CAM, Hugh P. - KELLIS, Manolis - TSAI, Li-Huei. Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes. In NATURE MEDICINE. ISSN 1078-8956, 2020, vol. 26, no. 6, pp. 952-+. SINGH, Manisha - PANDEY, Pranav K. - BHASIN, Ashu - PADMA, M. - MOHANTY, Sujata. Application of Stem Cells in Stroke: A Multifactorial Approach. In FRONTIERS IN NEUROSCIENCE, 2020, vol. 14, no., pp. BRANSCOME, Heather - PAUL, Siddhartha - YIN, Dezhong - EL-HAGE, Nazira - AGBOTTAH, Emmanuel T. - ZADEH, Mohammad Asad - LIOTTA, Lance A. - KASHANCHI, Fatah. Use of Stem Cell Extracellular Vesicles as a "Holistic" Approach to CNS Repair. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, 2020, vol. 8, no., pp. HERNANDEZ-SAPIENS, Mercedes A. - REZA-ZALDIVAR, Edwin E. - CEVALLOS, Ricardo R. - MARQUEZ-AGUIRRE, Ana L. - GAZARIAN, Karlen - CANALES-AGUIRRE, Alejandro A. A Three-Dimensional Alzheimer's Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1. In FRONTIERS IN CELLULAR NEUROSCIENCE, 2020, vol. 14, no., pp. BOTTE, Alexandra - LAINE, Jeanne - XICOTA, Laura - HEILIGENSTEIN, Xavier - FONTAINE, Gaelle - KASRI, Amal - RIVALS, Isabelle - GOH, Pollyanna - FAKLARIS, Orestis - COSSEC, Jack-Christophe - MOREL, Etienne - REBILLAT, Anne-Sophie - NIZETIC, Dean - RAPOSO, Graca - POTIER, Marie-Claude. Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome. In ACTA NEUROPATHOLOGICA COMMUNICATIONS. ISSN 2051-5960, 2020, vol. 8, no. 1, pp. SCEARCE-LEVIE, Kimberly - SANCHEZ, Pascal E. - LEWCOCK, Joseph W. Leveraging preclinical models for the development of Alzheimer disease therapeutics. In NATURE REVIEWS DRUG DISCOVERY. ISSN 1474-1776, 2020, vol. 19, no. 7, pp. 447-462. SILVA, M. Catarina - HAGGARTY, Stephen J. Human pluripotent stem cell-derived models and drug screening in CNS precision medicine. In ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. ISSN 0077-8923, 2020, vol. 1471, no. 1, pp. 18-56. COLLINS, Lila R. - SHEPARD, Kelly A. CIRMtools and technologies: Breaking bottlenecks to the development of stem cell therapies. In STEM CELLS TRANSLATIONAL MEDICINE. ISSN 2157-6564, 2020, vol. 9, no. 10, pp. 1129-1136. KAMPMANN, Martin. CRISPR-based functional genomics for neurological disease. In NATURE REVIEWS NEUROLOGY. ISSN 1759-4758, 2020, vol. 16, no. 9, pp. 465-480. MAHONEY, Rebekah - THOMAS, Elizabeth Ochoa - RAMIREZ, Paulino - MILLER, Henry E. - BECKMANN, Adrian - ZUNIGA, Gabrielle - DOBROWOLSKI, Radek - FROST, Bess. Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium. In CELL REPORTS. ISSN 2211-1247, 2020, vol. 32, no. 2, pp. POMESHCHIK, Yuriy - KLEMENTIEVA, Oxana - GIL, Jeovanis - MARTINSSON, Isak - HANSEN, Marita Gronning - DE VRIES, Tessa - SANCHO-BALSELLS, Anna - RUSS, Kaspar - SAVCHENKO, Ekaterina - COLLIN, Anna - VAZ, Ana Rita - BAGNOLI, Silvia - NACMIAS, Benedetta - RAMPON, Claire - SORBI, Sandro - BRITES, Dora - MARKO-VARGA, Gyorrgy - KOKAIA, Zaal - REZELI, Melinda - GOURAS, Gunnar K. - ROYBON, Laurent. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies. In STEM CELL REPORTS. ISSN 2213-6711, 2020, vol. 15, no. 1, pp. 256-273. LEE, Davin - CHOI, Yoon Ha - SEO, Jinsoo - KIM, Jong Kyoung - LEE, Sung Bae. Discovery of new epigenomics-based biomarkers and the early diagnosis of neurodegenerative diseases. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, 2020, vol. 61, no., pp. ROMANO, G. - MARINO, I. R. Organoids and organs-on-chips: systems for disease modeling, drug screening and identification of environmental risk factors for human illnesses. In DRUGS OF THE FUTURE. ISSN 0377-8282, 2020, vol. 45, no. 8, pp. 553-563. BUSCHE, Marc Aurel - HYMAN, Bradley T. Synergy between amyloid-beta and tau in Alzheimer's disease. In NATURE NEUROSCIENCE. ISSN 1097-6256, 2020, vol. 23, no. 10, pp. 1183-1193. LIU, Xin-Yu - YANG, Lin-Po - ZHAO, Lan. Stem cell therapy for Alzheimer's disease. In WORLD JOURNAL OF STEM CELLS. ISSN 1948-0210, 2020, vol. 12, no. 8, pp. 787-802. LEE, Christopher - WILLERTH, Stephanie M. - NYGAARD, Haakon B. The Use of Patient-Derived Induced Pluripotent Stem Cells for Alzheimer's Disease Modeling. In PROGRESS IN NEUROBIOLOGY. ISSN 0301-0082, 2020, vol. 192, no., pp. LAU, Dawn H. W. - PAILLUSSON, Sebastien - HARTOPP, Naomi - RUPAWALA, Huzefa - MOROTZ, Gabor M. - GOMEZ-SUAGA, Patricia - GREIG, Jenny - TROAKES, Claire - NOBLE, Wendy - MILLER, Christopher C. J. Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, 2020, vol. 143, no., pp. FLANAGAN, Emma - LAMPORT, Daniel - BRENNAN, Lorraine - BURNET, Philip - CALABRESE, Vittorio - CUNNANE, Stephen C. - DE WILDE, Martijn C. - DYE, Louise - FARRIMOND, Jonathan A. - LOMBARDO, Nancy Emerson - HARTMANN, Tobias - HARTUNG, Thomas - KALLIOMAKI, Marko - KUHNLE, Gunther G. - LA FATA, Giorgio - SALA-VILA, Aleix - SAMIERI, Cecilia - SMITH, A. David - SPENCER, Jeremy P. E. - THURET, Sandrine - TUOHY, Kieran - TURRONI, Silvia - VANDEN BERGHE, Wim - VERKUIJL, Martin - VERZIJDEN, Karin - YANNAKOULIA, Mary - GEURTS, Lucie - VAUZOUR, David. Nutrition and the ageing brain: Moving towards clinical applications. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, 2020, vol. 62, no., pp. ARGENTATI, Chiara - TORTORELLA, Ilaria - BAZZUCCHI, Martina - EMILIANI, Carla - MORENA, Francesco - MARTINO, Sabata. The Other Side of Alzheimer's Disease: Influence of Metabolic Disorder Features for Novel Diagnostic Biomarkers. In JOURNAL OF PERSONALIZED MEDICINE, 2020, vol. 10, no. 3, pp. GARCIA-LEON, Juan Antonio - CACERES-PALOMO, Laura - SANCHEZ-MEJIAS, Elisabeth - MEJIAS-ORTEGA, Marina - NUNEZ-DIAZ, Cristina - FERNANDEZ-VALENZUELA, Juan Jose - SANCHEZ-VARO, Raquel - DAVILA, Jose Carlos - VITORICA, Javier - GUTIERREZ, Antonia. Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, vol. 21, no. 18, pp. RANJAN, Vivek Damodar - QIU, Lifeng - LEE, Jolene Wei-Ling - CHEN, Xuelong - JANG, Se Eun - CHAI, Chou - LIM, Kah-Leong - TAN, Eng-King - ZHANG, Yilei - HUANG, Wei Min - ZENG, Li. A microfiber scaffold-based 3Din vitrohuman neuronal culture model of Alzheimer's disease. In BIOMATERIALS SCIENCE. ISSN 2047-4830, 2020, vol. 8, no. 17, pp. 4861-4874. TANG, Yueyu - HAN, Yingying - YU, Hongxiang - ZHANG, Bei - LI, Gang. Increased GABAergic development in iPSC-derived neurons from patients with sporadic Alzheimer's disease. In NEUROSCIENCE LETTERS. ISSN 0304-3940, 2020, vol. 735, no., pp. CHOI, Won-Young - HWANG, Ji-Hyun - LEE, Jin-Young - CHO, Ann-Na - LEE, Andrew J. - JUNG, Inkyung - CHO, Seung-Woo - KIM, Lark Kyun - KIM, Young-Joon. Chromatin Interaction Changes during the iPSC-NPC Model to Facilitate the Study of Biologically Significant Genes Involved in Differentiation. In GENES, 2020, vol. 11, no. 10, pp. TAO, Ran - LU, Rui - WANG, Junfeng - ZENG, Shujun - ZHANG, Ting - GUO, Wenke - ZHANG, Xiaobing - CHENG, Qi - YUE, Chunmei - WANG, Yizheng - JING, Naihe. Probing the therapeutic potential of TRPC6 for Alzheimer's disease in live neurons from patient-specific iPSCs. In JOURNAL OF MOLECULAR CELL BIOLOGY. ISSN 1674-2788, 2020, vol. 12, no. 10, pp. 807-816. GALIAKBEROVA, Adelya A. - DASHINIMAEV, Erdem B. Neural Stem Cells and Methods for Their Generation From Induced Pluripotent Stem Cellsin vitro. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, 2020, vol. 8, no., pp. FANG, Jiansong - PIEPER, Andrew A. - NUSSINOV, Ruth - LEE, Garam - BEKRIS, Lynn - LEVERENZ, James B. - CUMMINGS, Jeffrey - CHENG, Feixiong. Harnessing endophenotypes and network medicine for Alzheimer's drug repurposing. In MEDICINAL RESEARCH REVIEWS. ISSN 0198-6325, 2020, vol. 40, no. 6, pp. 2386-2426. CALDWELL, Andrew B. - LIU, Qing - SCHROTH, Gary P. - GALASKO, Douglas R. - YUAN, Shauna H. - WAGNER, Steven L. - SUBRAMANIAM, Shankar. Dedifferentiation and neuronal repression define familial Alzheimer's disease. In SCIENCE ADVANCES. ISSN 2375-2548, 2020, vol. 6, no. 46, pp. ARBER, Charles - TOOMBS, Jamie - LOVEJOY, Christopher - RYAN, Natalie S. - PATERSON, Ross W. - WILLUMSEN, Nanet - GKANATSIOU, Eleni - PORTELIUS, Erik - BLENNOW, Kaj - HESLEGRAVE, Amanda - SCHOTT, Jonathan M. - HARDY, John - LASHLEY, Tammaryn - FOX, Nick C. - ZETTERBERG, Henrik - WRAY, Selina. Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2020, vol. 25, no. 11, pp. 2919-2931. ZHAO, Jing - FU, Yuan - YAMAZAKI, Yu - REN, Yingxue - DAVIS, Mary D. - LIU, Chia-Chen - LU, Wenyan - WANG, Xue - CHEN, Kai - CHERUKURI, Yesesri - JIA, Lin - MARTENS, Yuka A. - JOB, Lucy - SHUE, Francis - THANH THANH NGUYEN - YOUNKIN, Steven G. - GRAFF-RADFORD, Neill R. - WSZOLEK, Zbigniew K. - BRAFMAN, David A. - ASMANN, Yan W. - ERTEKIN-TANER, Nilufer - KANEKIYO, Takahisa - BU, Guojun. APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids. In NATURE COMMUNICATIONS. ISSN 2041-1723, 2020, vol. 11, no. 1, pp. ZABOLOCKI, Michael - MCCORMACK, Kasandra - VAN DEN HURK, Mark - MILKY, Bridget - SHOUBRIDGE, Andrew P. - ADAMS, Robert - TRAN, Jenne - MAHADEVAN-JANSEN, Anita - REINECK, Philipp - THOMAS, Jacob - HUTCHINSON, Mark R. - MAK, Carmen K. H. - ANONUEVO, Adam - CHEW, Leon H. - HIRST, Adam J. - LEE, Vivian M. - KNOCK, Erin - BARDY, Cedric. BrainPhys neuronal medium optimized for imaging and optogenetics in vitro. In NATURE COMMUNICATIONS. ISSN 2041-1723, 2020, vol. 11, no. 1, pp. GUHA, Sanjib - FISCHER, Sarah - JOHNSON, Gail V. W. - NEHRKE, Keith. Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model. In MOLECULAR NEURODEGENERATION, 2020, vol. 15, no. 1, pp. ROBIN, Gaelle - EVANS, J. Corey - HAUSER, David N. - WREN, Paul - ZEMBRZYCKI, Andreas. Longitudinal Characterization of Transcriptomic, Functional, and Morphological Features in Human iPSC-Derived Neurons and Their Application to Investigate Translational Progranulin Disease Biology. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, 2020, vol. 12, no., pp. ZHANG, Ying - XIE, Xinyang - HU, Jiangnan - AFREEN, Kazi Sabrina - ZHANG, Chun-Li - ZHUGE, Qichuan - YANG, Jianjing. Prospects of Directly Reprogrammed Adult Human Neurons for Neurodegenerative Disease Modeling and Drug Discovery: iN vs. iPSCs Models. In FRONTIERS IN NEUROSCIENCE, 2020, vol. 14, no., pp. PENSALFINI, Anna - KIM, Seonil - SUBBANNA, Shivakumar - BLEIWAS, Cynthia - GOULBOURNE, Chris N. - STAVRIDES, Philip H. - JIANG, Ying - LEE, Ju-Hyun - DARJI, Sandipkumar - PAWLIK, Monika - HUO, Chunfeng - PEDDY, James - BERG, Martin J. - SMILEY, John F. - BASAVARAJAPPA, Balapal S. - NIXON, Ralph A. Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease. In CELL REPORTS. ISSN 2211-1247, 2020, vol. 33, no. 8, pp. SIMOES, Sabrina - NEUFELD, Jessica L. - TRIANA-BALTZER, Gallen - MOUGHADAM, Setareh - CHEN, Emily - KOTHIYA, Milankumar - QURESHI, Yasir H. - PATEL, Vivek - HONIG, Lawrence S. - KOLB, Hartmuth - SMALL, Scott A. Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans. In SCIENCE TRANSLATIONAL MEDICINE. ISSN 1946-6234, 2020, vol. 12, no. 571, pp. HOSSEINI, Kimia - LEKHOLM, Emilia - AHEMAITI, Aikeremu - FREDRIKSSON, Robert. Differentiation of Human Embryonic Stem Cells into Neuron, Cholinergic, and Glial Cells. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2020, vol. 2020, no., pp. FINKBEINER, Steven. Functional genomics, genetic risk profiling and cell phenotypes in neurodegenerative disease. In NEUROBIOLOGY OF DISEASE. ISSN 0969-9961, 2020, vol. 146, no., pp. VALADEZ-BARBA, Valeria - COTA-CORONADO, A. - HERNANDEZ-PEREZ, O. R. - LUGO-FABRES, Pavel H. - PADILLA-CAMBEROS, Eduardo - FABIAN DIAZ, Nestor - EMMANUEL DIAZ-MARTINEZ, N. iPSC for modeling neurodegenerative disorders. In REGENERATIVE THERAPY. ISSN 2352-3204, 2020, vol. 15, no., pp. 332-339. PODLESNY-DRABINIOK, Anna - MARCORA, Edoardo - GOATE, Alison M. Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer's Disease Genetics. In TRENDS IN NEUROSCIENCES. ISSN 0166-2236, 2020, vol. 43, no. 12, pp. 965-979. LIU, Sijun - ZHAO, Yuying - SU, Xiaoying - ZHOU, Chengcheng - YANG, Peifen - LIN, Qiusan - LI, Shijun - TAN, Hanxu - WANG, Qi - WANG, Changjun - WU, Qingguang. Reconstruction of Alzheimer's Disease Cell Model In Vitro via Extracted Peripheral Blood Molecular Cells from a Sporadic Patient. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2020, vol. 2020, no., pp. ZOU, Yulian - GAN, Chen-Ling - XIN, Zhiming - ZHANG, Hai-Tao - ZHANG, Qi - LEE, Tae Ho - PAN, Xiaodong - CHEN, Zhou. Programmed Cell Death Protein 1 Blockade Reduces Glycogen Synthase Kinase 3 beta Activity and Tau Hyperphosphorylation in Alzheimer's Disease Mouse Models. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, 2021, vol. 9, no., pp. Dostupné na: https://doi.org/10.3389/fcell.2021.769229. CHAVES, Rodrigo S. - MY TRAN - HOLDER, Andrew R. - BALCER, Alexandra M. - DICKEY, Andrea M. - ROBERTS, Elizabeth A. - BOBER, Brian G. - GUTIERREZ, Edgar - HEAD, Brian P. - GROISMAN, Alex - GOLDSTEIN, Lawrence S. B. - ALMENAR-QUERALT, Angels - SHAH, Sameer B. Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons. In JOURNAL OF NEUROSCIENCE. ISSN 0270-6474, 2021, vol. 41, no. 49, pp. 10034-10053. Dostupné na: https://doi.org/10.1523/JNEUROSCI.2553-20.2021. SAWA, Mariko - OVERK, Cassia - BECKER, Ann - DERSE, Dominique - ALBAY, Ricardo - WELDY, Kim - SALEHI, Ahmad - BEACH, Thomas G. - DORAN, Eric - HEAD, Elizabeth - YU, Y. Eugene - MOBLEY, William C. Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model. In ALZHEIMERS & DEMENTIA. ISSN 1552-5260, 2021, vol., no., pp. Dostupné na: https://doi.org/10.1002/alz.12463. SUPAKUL, Sopak - OKANO, Hideyuki - MAEDA, Sumihiro. Utilization of Human Induced Pluripotent Stem Cells-Derived In vitro Models for the Future Study of Sex Differences in Alzheimer's Disease. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, 2021, vol. 13, no., pp. Dostupné na: https://doi.org/10.3389/fnagi.2021.768948. LAGOMARSINO, Valentina N. - PEARSE, Richard V. - LIU, Lei - HSIEH, Yi-Chen - FERNANDEZ, Marty A. - VINTON, Elizabeth A. - PAULL, Daniel - FELSKY, Daniel - TASAKI, Shinya - GAITERI, Chris - VARDARAJAN, Badri - LEE, Hyo - MURATORE, Christina R. - BENOIT, Courtney R. - CHOU, Vicky - FANCHER, Seeley B. - HE, Amy - MERCHANT, Julie P. - DUONG, Duc M. - MARTINEZ, Hector - ZHOU, Monica - BAH, Fatmata - VICENT, Maria A. - STRICKER, Jonathan M. S. - XU, Jishu - DAMMER, Eric B. - LEVEY, Allan - CHIBNIK, Lori B. - MENON, Vilas - SEYFRIED, Nicholas T. - DE JAGER, Philip L. - NOGGLE, Scott - SELKOE, Dennis J. - BENNETT, David A. - YOUNG-PEARSE, Tracy L. Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. In NEURON. ISSN 0896-6273, 2021, vol. 109, no. 21, pp. 3402-+. Dostupné na: https://doi.org/10.1016/j.neuron.2021.08.003. HWANG, Joel Jihwan - CHOI, Jinhyeok - RIM, Yeri Alice - NAM, Yoojun - JU, Ji Hyeon. Application of Induced Pluripotent Stem Cells for Disease Modeling and 3D Model Construction: Focus on Osteoarthritis. In CELLS, 2021, vol. 10, no. 11, pp. Dostupné na: https://doi.org/10.3390/cells10113032. PRASANNA, Pragya - RATHEE, Shweta - RAHUL, Vedanabhatla - MANDAL, Debabrata - CHANDRA GOUD, Macherla Sharath - YADAV, Pardeep - HAWTHORNE, Susan - SHARMA, Ankur - GUPTA, Piyush Kumar - OJHA, Shreesh - JHA, Niraj Kumar - VILLA, Chiara - JHA, Saurabh Kumar. Microfluidic Platforms to Unravel Mysteries of Alzheimer's Disease: How Far Have We Come? In LIFE-BASEL, 2021, vol. 11, no. 10, pp. Dostupné na: https://doi.org/10.3390/life11101022. MATSUMOTO, Ryusaku - YAMAMOTO, Takuya - TAKAHASHI, Yutaka. Complex Organ Construction from Human Pluripotent Stem Cells for Biological Research and Disease Modeling with New Emerging Techniques. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, vol. 22, no. 19, pp. Dostupné na: https://doi.org/10.3390/ijms221910184. KUO, Chih-Chung - CHIANG, Austin W. T. - BAGHDASSARIAN, Hratch M. - LEWIS, Nathan E. Dysregulation of the secretory pathway connects Alzheimer's disease genetics to aggregate formation. In CELL SYSTEMS. ISSN 2405-4712, 2021, vol. 12, no. 9, pp. 873-+. Dostupné na: https://doi.org/10.1016/j.cels.2021.06.001. INOUE, Keiichi. CRISPR-activated patient fibroblasts for modeling of familial Alzheimer's disease. In NEUROSCIENCE RESEARCH. ISSN 0168-0102, 2021, vol. 172, no., pp. 7-12. Dostupné na: https://doi.org/10.1016/j.neures.2021.03.008. MERTENS, Jerome - HERDY, Joseph R. - TRAXLER, Larissa - SCHAFER, Simon T. - SCHLACHETZKI, Johannes C. M. - BOHNKE, Lena - REID, Dylan A. - LEE, Hyungjun - ZANGWILL, Dina - FERNANDES, Diana P. - AGARWAL, Ravi K. - LUCCIOLA, Raffaella - ZHOU-YANG, Lucia - KARBACHER, Lukas - EDENHOFER, Frank - STERN, Shani - HORVATH, Steve - PAQUOLA, Apua C. M. - GLASS, Christopher K. - YUAN, Shauna H. - KU, Manching - SZUCS, Attila - GOLDSTEIN, Lawrence S. B. - GALASKO, Douglas - GAGE, Fred H. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. In CELL STEM CELL. ISSN 1934-5909, 2021, vol. 28, no. 9, pp. 1533-+. Dostupné na: https://doi.org/10.1016/j.stem.2021.04.004. CHEN, Carol X-Q - ABDIAN, Narges - MAUSSION, Gilles - THOMAS, Rhalena A. - DEMIROVA, Iveta - CAI, Eddie - TABATABAEI, Mahdieh - BEITEL, Lenore K. - KARAMCHANDANI, Jason - FON, Edward A. - DURCAN, Thomas M. A Multistep Workflow to Evaluate Newly Generated iPSCs and Their Ability to Generate Different Cell Types. In METHODS AND PROTOCOLS, 2021, vol. 4, no. 3, pp. Dostupné na: https://doi.org/10.3390/mps4030050. BI, Feng-Chen - YANG, Xin-He - CHENG, Xiao-Yu - DENG, Wen-Bin - GUO, Xiao-Li - YANG, Hui - WANG, Yin - LI, Juan - YAO, Yao. Optimization of cerebral organoids: a more qualified model for Alzheimer's disease research. In TRANSLATIONAL NEURODEGENERATION. ISSN 2047-9158, 2021, vol. 10, no. 1, pp. Dostupné na: https://doi.org/10.1186/s40035-021-00252-3. TRUDLER, Dorit - GHATAK, Swagata - LIPTON, Stuart A. Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, vol. 22, no. 15, pp. Dostupné na: https://doi.org/10.3390/ijms22158196. RYU, Woo-In - COHEN, Bruce M. - SONNTAG, Kai-C. Hypothesis and Theory: Characterizing Abnormalities of Energy Metabolism Using a Cellular Platform as a Personalized Medicine Approach for Alzheimer's Disease. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, 2021, vol. 9, no., pp. Dostupné na: https://doi.org/10.3389/fcell.2021.697578. HATTERSLEY, Kathryn J. - CAROSI, Julian M. - HEIN, Leanne K. - BENSALEM, Julien - SARGEANT, Timothy J. PICALM regulates cathepsin D processing and lysosomal function. In BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. ISSN 0006-291X, 2021, vol. 570, no., pp. 103-109. Dostupné na: https://doi.org/10.1016/j.bbrc.2021.07.024. PATWARDHAN, Aryaman Girish - BELEMKAR, Sateesh. An update on Alzheimer's disease: Immunotherapeutic agents, stem cell therapy and gene editing. In LIFE SCIENCES. ISSN 0024-3205, 2021, vol. 282, no., pp. Dostupné na: https://doi.org/10.1016/j.lfs.2021.119790. FERRARI, Camilla - SORBI, Sandro. THE COMPLEXITY OF ALZHEIMER'SDISEASE: AN EVOLVING PUZZLE. In PHYSIOLOGICAL REVIEWS. ISSN 0031-9333, 2021, vol. 101, no. 3, pp. 1047-1081. Dostupné na: https://doi.org/10.1152/physrev.00015.2020. HUNG, Christy - TUCK, Eleanor - STUBBS, Victoria - VAN DER LEE, Sven J. - AALFS, Cora - VAN SPAENDONK, Resie - SCHELTENS, Philip - HARDY, John - HOLSTEGE, Henne - LIVESEY, Frederick J. SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network. In CELL REPORTS. ISSN 2211-1247, 2021, vol. 35, no. 11, pp. Dostupné na: https://doi.org/10.1016/j.celrep.2021.109259. ELSWORTHY, Richard J. - KING, Marianne C. - GRAINGER, Alastair - FISHER, Emily - CROWE, James A. - ALQATTAN, Sarah - LUDLAM, Adele - HILL, Eric J. - ALDRED, Sarah. Amyloid-beta precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiation. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, 2021, vol. 114, no., pp. Dostupné na: https://doi.org/10.1016/j.mcn.2021.103631. DRABIK, Karolina - MALINSKA, Dominika - PIECYK, Karolina - DEBSKA-VIELHABER, Grazyna - VIELHABER, Stefan - DUSZYNSKI, Jerzy - SZCZEPANOWSKA, Joanna. Effect of Chronic Stress Present in Fibroblasts Derived from Patients with a Sporadic Form of AD on Mitochondrial Function and Mitochondrial Turnover. In ANTIOXIDANTS, 2021, vol. 10, no. 6, pp. Dostupné na: https://doi.org/10.3390/antiox10060938. SUMA, Sarojini - RASHMI, Agarwal. Genetic Causes of Male Infertility and Emerging Potential of Stem Cell Therapeutics. In RESEARCH JOURNAL OF BIOTECHNOLOGY. ISSN 2278-4535, 2021, vol. 16, no. 6, pp. 183-189. SCHULZ, Joseph M. The Potential of Induced Pluripotent Stem Cells to Treat and Model Alzheimer's Disease. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2021, vol. 2021, no., pp. Dostupné na: https://doi.org/10.1155/2021/5511630. GUTOVA, M. - CHENG, J. - TSATURYAN, L. - NELSON, M. - BARISH, M. - ROCKNE, R. - BONDI, C. - KLINE, A. Intranasally Administered L-Myc Immortalized Human Neural Stem Cells Migrate to Primary and Distal Sites of Damage After Cortical Impact and Enhance Spatial Learning. In JOURNAL OF HEAD TRAUMA REHABILITATION. ISSN 0885-9701, 2020, vol. 35, no. 2, pp. E223-E224. PODVIN, Sonia - JONES, Alexander - LIU, Qing - AULSTON, Brent - MOSIER, Charles - AMES, Janneca - WINSTON, Charisse - LIETZ, Christopher B. - JIANG, Zhenze - O'DONOGHUE, Anthony J. - IKEZU, Tsuneya - RISSMAN, Robert A. - YUAN, Shauna H. - HOOK, Vivian. Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons. In ACS OMEGA. ISSN 2470-1343, 2021, vol. 6, no. 20, pp. 13033-13056. Dostupné na: https://doi.org/10.1021/acsomega.1c00660. GANESAN, Dhasarathan - CAI, Qian. Understanding amphisomes. In BIOCHEMICAL JOURNAL. ISSN 0264-6021, 2021, vol. 478, no. 10, pp. 1959-1976. Dostupné na: https://doi.org/10.1042/BCJ20200917. AMPONSAH, Asiamah Ernest - GUO, Ruiyun - KONG, Desheng - FENG, Baofeng - HE, Jingjing - ZHANG, Wei - LIU, Xin - DU, Xiaofeng - MA, Zhenhuan - LIU, Boxin - MA, Jun - CUI, Huixian. Patient-derived iPSCs, a reliable in vitro model for the investigation of Alzheimer's disease. In REVIEWS IN THE NEUROSCIENCES. ISSN 0334-1763, 2021, vol. 32, no. 4, pp. 379-402. Dostupné na: https://doi.org/10.1515/revneuro-2020-0065. SI, Zizhen - WANG, Xidi. Stem Cell Therapies in Alzheimer's Disease: Applications for Disease Modeling. In JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. ISSN 0022-3565, 2021, vol. 377, no. 2, pp. 207-217. Dostupné na: https://doi.org/10.1124/jpet.120.000324. BROOKHOUSER, Nicholas - RAMAN, Sreedevi - FRISCH, Carlye - SRINIVASAN, Gayathri - BRAFMAN, David A. APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer's disease. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2021, vol. 26, no. 10, pp. 5715-5732. Dostupné na: https://doi.org/10.1038/s41380-021-01076-3. TRUJILLO-ESTRADA, Laura - SANCHEZ-MEJIAS, Elisabeth - SANCHEZ-VARO, Raquel - ANTONIO GARCIA-LEON, Juan - NUNEZ-DIAZ, Cristina - CARLOS DAVILA, Jose - VITORICA, Javier - LAFERLA, Frank M. - MORENO-GONZALEZ, Ines - GUTIERREZ, Antonia - BAGLIETTO-VARGAS, David. Animal and Cellular Models of Alzheimer's Disease: Progress, Promise, and Future Approaches. In NEUROSCIENTIST. ISSN 1073-8584, 2021, vol., no., pp. Dostupné na: https://doi.org/10.1177/10738584211001753. HANNA, Roy - FLAMIER, Anthony - BARABINO, Andrea - BERNIER, Gilbert. G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease. In NATURE COMMUNICATIONS. ISSN 2041-1723, 2021, vol. 12, no. 1, pp. Dostupné na: https://doi.org/10.1038/s41467-021-22129-9. KONIJNENBERG, Elles - TOMASSEN, Jori - DEN BRABER, Anouk - TEN KATE, Mara - YAQUB, Maqsood - MULDER, Sandra D. - NIVARD, Michel G. - VANDERSTICHELE, Hugo - LAMMERTSMA, Adriaan A. - TEUNISSEN, Charlotte E. - VAN BERCKEL, Bart N. M. - BOOMSMA, Dorret - SCHELTENS, Philip - TIJMS, Betty M. - VISSER, Pieter Jelle. Onset of Preclinical Alzheimer Disease in Monozygotic Twins. In ANNALS OF NEUROLOGY. ISSN 0364-5134, 2021, vol. 89, no. 5, pp. 987-1000. Dostupné na: https://doi.org/10.1002/ana.26048. MACDOUGALL, Gabriella - BROWN, Logan Y. - KANTOR, Boris - CHIBA-FALEK, Ornit. The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models. In MOLECULAR THERAPY. ISSN 1525-0016, 2021, vol. 29, no. 3, pp. 949-972. Dostupné na: https://doi.org/10.1016/j.ymthe.2021.01.001. FRANKOWSKI, Harald - YEBOAH, Fred - BERRY, Bonnie J. - KINOSHITA, Chizuru - LEE, Michelle - EVITTS, Kira - DAVIS, Joshua - KINOSHITA, Yoshito - MORRISON, Richard S. - YOUNG, Jessica E. Knock-Down of HDAC2 in Human Induced Pluripotent Stem Cell Derived Neurons Improves Neuronal Mitochondrial Dynamics, Neuronal Maturation and Reduces Amyloid Beta Peptides. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, vol. 22, no. 5, pp. Dostupné na: https://doi.org/10.3390/ijms22052526. WATANABE, Hirotaka - IMAIZUMI, Kent - CAI, Tetsuo - ZHOU, Zhi - TOMITA, Taisuke - OKANO, Hideyuki. Flexible and Accurate Substrate Processing with Distinct Presenilin/gamma-Secretases in Human Cortical Neurons. In ENEURO, 2021, vol. 8, no. 2, pp. Dostupné na: https://doi.org/10.1523/ENEUR0.0500-20.2021. ANDO, Kunie - ERNEUX, Christophe - HOMA, Megane - HOUBEN, Sarah - DE FISENNE, Marie-Ange - BRION, Jean-Pierre - LEROY, Karelle. Dysregulation of Phosphoinositide 5-Phosphatases and Phosphoinositides in Alzheimer's Disease. In FRONTIERS IN NEUROSCIENCE, 2021, vol. 15, no., pp. Dostupné na: https://doi.org/10.3389/fnins.2021.614855. PASTEUNING-VUHMAN, Svetlana - DE JONGH, Rianne - TIMMERS, Annabel - PASTERKAMP, R. Jeroen. Towards Advanced iPSC-based Drug Development for Neurodegenerative Disease. In TRENDS IN MOLECULAR MEDICINE. ISSN 1471-4914, 2021, vol. 27, no. 3, pp. 263-279. Dostupné na: https://doi.org/10.1016/j.molmed.2020.09.013. WRAY, Selina. Modelling neurodegenerative disease using brain organoids. In SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. ISSN 1084-9521, 2021, vol. 111, no., pp. 60-66. Dostupné na: https://doi.org/10.1016/j.semcdb.2020.05.012. WANG, Mian - XIN, Yuanfeng - CAO, Hao - LI, Wanlu - HUA, Yifei - WEBSTER, Thomas J. - ZHANG, Chao - TANG, Wenjie - LIU, Zhongmin. Recent advances in mesenchymal stem cell membrane-coated nanoparticles for enhanced drug delivery. In BIOMATERIALS SCIENCE. ISSN 2047-4830, 2021, vol. 9, no. 4, pp. 1088-1103. Dostupné na: https://doi.org/10.1039/d0bm01164a. LIM, HoTae - CHOI, In Young - HYUN, Sang-Hwan - KIM, Hyesoo - LEE, Gabsang. Approaches to characterize the transcriptional trajectory of human myogenesis. In CELLULAR AND MOLECULAR LIFE SCIENCES. ISSN 1420-682X, 2021, vol. 78, no. 9, pp. 4221-4234. Dostupné na: https://doi.org/10.1007/s00018-021-03782-1. YE, Tao - DUAN, Yangyang - TSANG, Hayley W. S. - XU, He - CHEN, Yuewen - CAO, Han - CHEN, Yu - FU, Amy K. Y. - IP, Nancy Y. Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases. In COMMUNICATIONS BIOLOGY, 2021, vol. 4, no. 1, pp. Dostupné na: https://doi.org/10.1038/s42003-021-01722-0. DAVIS, Oliver B. - SHIN, Hijai R. - LIM, Chun-Yan - WU, Emma Y. - KUKURUGYA, Matthew - MAHER, Claire F. - PERERA, Rushika M. - ORDONEZ, M. Paulina - ZONCU, Roberto. NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C. In DEVELOPMENTAL CELL. ISSN 1534-5807, 2021, vol. 56, no. 3, pp. 260-+. Dostupné na: https://doi.org/10.1016/j.devcel.2020.11.016. KONSTANTOULEA, Katerina - LOUROS, Nikolaos - ROUSSEAU, Frederic - SCHYMKOWITZ, Joost. Heterotypic interactions in amyloid function and disease. In FEBS JOURNAL. ISSN 1742-464X, 2021, vol., no., pp. Dostupné na: https://doi.org/10.1111/febs.15719. TROMBETTA-LIMA, Marina - SABOGAL-GUAQUETA, Angelica Maria - DOLGA, Amalia M. Mitochondrial dysfunction in neurodegenerative diseases: A focus on iPSC-derived neuronal models. In CELL CALCIUM. ISSN 0143-4160, 2021, vol. 94, no., pp. Dostupné na: https://doi.org/10.1016/j.ceca.2021.102362. GUPTA, Swapnil - YOU, Panpan - SENGUPTA, Tanima - NILSEN, Hilde - SHARMA, Kulbhushan. Crosstalk between Different DNA Repair Pathways Contributes to Neurodegenerative Diseases. In BIOLOGY-BASEL, 2021, vol. 10, no. 2, pp. Dostupné na: https://doi.org/10.3390/biology10020163. LANGNESS, Vanessa F. - VAN DER KANT, Rik - DAS, Utpal - WANG, Louie - CHAVES, Rodrigo dos Santos - GOLDSTEIN, Lawrence S. B. Cholesterol-lowering drugs reduce APP processing to A beta by inducing APP dimerization. In MOLECULAR BIOLOGY OF THE CELL. ISSN 1059-1524, 2021, vol. 32, no. 3, pp. 247-259. Dostupné na: https://doi.org/10.1091/mbc.E20-05-0345. SOHEILI, Masoud - KARIMIAN, Mohammad - HAMIDI, Gholamali - SALAMI, Mahmoud. Alzheimer's disease treatment: The share of herbal medicines. In IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES. ISSN 2008-3866, 2021, vol. 24, no. 2, pp. 123-135. Dostupné na: https://doi.org/10.22038/IJBMS.2020.50536.11512. DE RUS JACQUET, Aurelie - DENIS, Helena L. - CICCHETTI, Francesca - ALPAUGH, Melanie. Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders. In MOLECULAR PSYCHIATRY. ISSN 1359-4184, 2021, vol. 26, no. 7, pp. 2685-2706. Dostupné na: https://doi.org/10.1038/s41380-020-00999-7. PARK, Jong-Chan - JANG, So-Yeong - LEE, Dongjoon - LEE, Jeongha - KANG, Uiryong - CHANG, Hongjun - KIM, Haeng Jun - HAN, Sun-Ho - SEO, Jinsoo - CHOI, Murim - LEE, Dong Young - BYUN, Min Soo - YI, Dahyun - CHO, Kwang-Hyun - MOOK-JUNG, Inhee. A logical network-based drug-screening platform for Alzheimer's disease representing pathological features of human brain organoids. In NATURE COMMUNICATIONS, 2021, vol. 12, no. 1, pp. Dostupné na: https://doi.org/10.1038/s41467-020-20440-5. CENINI, Giovanna - HEBISCH, Matthias - IEFREMOVA, Vira - FLITSCH, Lea J. - BREITKREUZ, Yannik - TANZI, Rudolph E. - KIM, Doo Yeon - PEITZ, Michael - BRUESTLE, Oliver. Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models. In MOLECULAR AND CELLULAR NEUROSCIENCE. ISSN 1044-7431, 2021, vol. 110, no., pp. Dostupné na: https://doi.org/10.1016/j.mcn.2020.103568. HARSCHNITZ, Oliver - STUDER, Lorenz. Human stem cell models to study host-virus interactions in the central nervous system. In NATURE REVIEWS IMMUNOLOGY. ISSN 1474-1733, 2021, vol. 21, no. 7, pp. 441-453. Dostupné na: https://doi.org/10.1038/s41577-020-00474-y. ZOUBOULIS, Christos C. - MAKRANTONAKI, Evgenia - HOSSINI, Amir M. Skin Mirrors Brain: A Chance for Alzheimer's Disease Research. In GENEDIS 2020: GENETICS AND NEURODEGENERATIVE DISEASES. ISSN 0065-2598, 2021, vol. 1339, no., pp. Dostupné na: https://doi.org/10.1007/978-3-030-78787-5_45. JACOB, Fadi - SCHNOLL, Jordan G. - SONG, Hongjun - MING, Guo-li. Building the brain from scratch: Engineering region-specific brain organoids from human stem cells to study neural development and disease. In MOLECULAR MECHANISMS OF NEURAL DEVELOPMENT AND INSIGHTS INTO DISEASE. ISSN 0070-2153, 2021, vol. 142, no., pp. 477-530. Dostupné na: https://doi.org/10.1016/bs.ctdb.2020.12.011. SILVA, Ana M. - CEDERBALK, Anna - EBNER, Daniel - DI DANIEL, Elena. Chemical Probes in Cellular Assays for Target Validation and Screening in Neurodegeneration. In DISCOVERY AND UTILITY OF CHEMICAL PROBES IN TARGET DISCOVERY. ISSN 2055-1975, 2021, vol. 16, no., pp. 276-319. SILVA, Ana M. - CEDERBALK, Anna - EBNER, Daniel - DI DANIEL, Elena. Chemical Probes in Cellular Assays for Target Validation and Screening in Neurodegeneration. In DISCOVERY AND UTILITY OF CHEMICAL PROBES IN TARGET DISCOVERY. ISSN 2055-1975, 2021, vol. 16, no., pp. 276-319. AMICO, Claudia Dell' - TATA, Alice - PELLEGRINO, Enrica - ONORATI, Marco - CONTI, Luciano. Genome editing in stem cells for genetic neurodisorders. In CURING GENETIC DISEASES THROUGH GENOME REPROGRAMMING. ISSN 1877-1173, 2021, vol. 182, no., pp. 403-438. Dostupné na: https://doi.org/10.1016/bs.pmbts.2020.12.006. GOLDSTEIN, Lawrence S. B. - DAS, Utpal. The cellular machinery of post-endocytic APP trafficking in Alzheimer's disease: A future target for therapeutic intervention? In MOLECULAR BIOLOGY OF NEURODEGENERATIVE DISEASES: VISIONS FOR THE FUTURE, PT B. ISSN 1877-1173, 2021, vol. 177, no., pp. 109-122. Dostupné na: https://doi.org/10.1016/bs.pmbts.2020.08.001. CHOI, Dong-Kyu - KIM, Yong-Kyu - HOONYU, Ji - MIN, Sang-Hyun - PARK, Sang-Wook. Genome editing of hPSCs: Recent progress in hPSC-based disease modeling for understanding disease mechanisms. In REPROGRAMMING THE GENOME: CRISPR-CAS-BASED HUMAN DISEASE THERAPY. ISSN 1877-1173, 2021, vol. 181, no., pp. 271-287. Dostupné na: https://doi.org/10.1016/bs.pmbts.2021.01.020. YIN, Juan - VANDONGEN, Antonius M. Enhanced Neuronal Activity and Asynchronous Calcium Transients Revealed in a 3D Organoid Model of Alzheimer's Disease. In ACS BIOMATERIALS SCIENCE & ENGINEERING. ISSN 2373-9878, 2021, vol. 7, no. 1, pp. 254-264. Dostupné na: https://doi.org/10.1021/acsbiomaterials.0c01583. AYTON, Scott - BUSH, Ashley. beta-amyloid: The known unknowns. In AGEING RESEARCH REVIEWS. ISSN 1568-1637, 2021, vol. 65, no., pp. Dostupné na: https://doi.org/10.1016/j.arr.2020.101212. ZAYED, Mohamed A. - SULTAN, Samar - ALSAAB, Hashem O. - YOUSOF, Shimaa Mohammad - ALREFAEI, Ghadeer I. - ALSUBHI, Nouf H. - ALKARIM, Saleh - AL GHAMDI, Kholoud S. - BAGABIR, Sali Abubaker - JANA, Ankit - ALGHAMDI, Badrah S. - ATTA, Hazem M. - ASHRAF, Ghulam Md. Stem-Cell-Based Therapy: The Celestial Weapon against Neurological Disorders. In CELLS, 2022, vol. 11, no. 21, pp. Dostupné na: https://doi.org/10.3390/cells11213476. GARCIA, Goncalo - PINTO, Sara - FERREIRA, Sofia - LOPES, Daniela - SERRADOR, Maria Joao - FERNANDES, Adelaide - VAZ, Ana Rita - DE MENDONCA, Alexandre - EDENHOFER, Frank - MALM, Tarja - KOISTINAHO, Jari - BRITES, Dora. Emerging Role of miR-21-5p in Neuron-Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer's Disease. In CELLS, 2022, vol. 11, no. 21, pp. Dostupné na: https://doi.org/10.3390/cells11213377. MAGNI, Manuela - BOSSI, Beatrice - CONFORTI, Paola - GALIMBERTI, Maura - DEZI, Fabio - LISCHETTI, Tiziana - HE, Xiaoling - BARKER, Roger A. - ZUCCATO, Chiara - ESPUNY-CAMACHO, Ira - CATTANEO, Elena. Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid Models. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, vol. 23, no. 21, pp. Dostupné na: https://doi.org/10.3390/ijms232113159. NG, Bryan - ROWLAND, Helen A. - WEI, Tina - ARUNASALAM, Kanisa - HAYES, Emma Mee - KOYCHEV, Ivan - HEDEGAARD, Anne - RIBE, Elena M. - CHAN, Dennis - CHESSELL, Tharani - FFYTCHE, Dominic - GUNN, Roger N. - KOCAGONCU, Ece - LAWSON, Jennifer - MALHOTRA, Paresh A. - RIDHA, Basil H. - ROWE, James B. - THOMAS, Alan J. - ZAMBONI, Giovanna - BUCKLEY, Noel J. - CADER, Zameel M. - LOVESTONE, Simon - WADE-MARTINS, Richard. Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability. In BRAIN COMMUNICATIONS, 2022, vol. 4, no. 6, pp. Dostupné na: https://doi.org/10.1093/braincomms/fcac267. SABOUNI, Nasim - MARZOUNI, Hadi Zare - PALIZBAN, Sepideh - MEIDANINIKJEH, Sepideh - KESHARWANI, Prashant - JAMIALAHMADI, Tannaz - SAHEBKAR, Amirhossein. Role of curcumin and its nanoformulations in the treatment of neurological diseases through the effects on stem cells. In JOURNAL OF DRUG TARGETING, 2022, vol., no., pp. ISSN 1061-186X. Dostupné na: https://doi.org/10.1080/1061186X.2022.2141755. RICKNER, Hannah Drew - JIANG, Lulu - HONG, Rui - O'NEILL, Nicholas K. - MOJICA, Chromewell A. - SNYDER, Benjamin J. - ZHANG, Lushuang - SHAW, Dipan - MEDALLA, Maria - WOLOZIN, Benjamin - CHENG, Christine S. Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model. In NATURE COMMUNICATIONS, 2022, vol. 13, no. 1, pp. Dostupné na: https://doi.org/10.1038/s41467-022-34005-1. VAN DEN HURK, Mark - LAU, Shong - MARCHETTO, Maria C. - MERTENS, Jerome - STERN, Shani - CORTI, Olga - BRICE, Alexis - WINNER, Beate - WINKLER, Juergen - GAGE, Fred H. - BARDY, Cedric. Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons. In NPJ PARKINSONS DISEASE, 2022, vol. 8, no. 1, pp. Dostupné na: https://doi.org/10.1038/s41531-022-00400-0. EICHMUELLER, Oliver L. - KNOBLICH, Juergen A. Human cerebral organoids a new tool for clinical neurology research. In NATURE REVIEWS NEUROLOGY, 2022, vol. 18, no. 11, pp. 661-680. ISSN 1759-4758. Dostupné na: https://doi.org/10.1038/s41582-022-00723-9. SHIM, Yu Jeong - SHIN, Min Kyoung - JUNG, Junghyun - KOO, Bongseong - JANG, Wonhee. An in-silico approach to studying a very rare neurodegenerative disease using a disease with higher prevalence with shared pathways and genes: Cerebral adrenoleukodystrophy and Alzheimer's disease. In FRONTIERS IN MOLECULAR NEUROSCIENCE, 2022, vol. 15, no., pp. ISSN 1662-5099. Dostupné na: https://doi.org/10.3389/fnmol.2022.996698. SALA-JARQUE, Julia - ZIMKOWSKA, Karolina - AVILA, Jesus - FERRER, Isidro - ANTONIO DEL RIO, Jose. Towards a Mechanistic Model of Tau-Mediated Pathology in Tauopathies: What Can We Learn from Cell-Based In Vitro Assays? In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, vol. 23, no. 19, pp. Dostupné na: https://doi.org/10.3390/ijms231911527. ALGHAMDI, Abeer - BIRCH, David J. S. - VYSHEMIRSKY, Vladislav - ROLINSKI, Olaf J. Impact of the Flavonoid Quercetin on beta-Amyloid Aggregation Revealed by Intrinsic Fluorescence. In JOURNAL OF PHYSICAL CHEMISTRY B, 2022, vol., no., pp. ISSN 1520-6106. Dostupné na: https://doi.org/10.1021/acs.jpcb.2c02763. PRANTY, Abida Islam - SHUMKA, Sara - ADJAYE, James. Bilirubin-Induced Neurological Damage: Current and Emerging iPSC-Derived Brain Organoid Models. In CELLS, 2022, vol. 11, no. 17, pp. Dostupné na: https://doi.org/10.3390/cells11172647. FERNANDEZ, Marty A. - BAH, Fatmata - MA, Li - LEE, YouJin - SCHMIDT, Michael - WELCH, Elizabeth - MORROW, Eric M. - YOUNG-PEARSE, Tracy L. Loss of endosomal exchanger NHE6 leads to pathological changes in tau in human neurons. In STEM CELL REPORTS, 2022, vol. 17, no. 9, pp. 2111-2126. ISSN 2213-6711. Dostupné na: https://doi.org/10.1016/j.stemcr.2022.08.001. SEN, Tirthankar - THUMMER, Rajkumar P. CRISPR and iPSCs: Recent Developments and Future Perspectives in Neurodegenerative Disease Modelling, Research, and Therapeutics. In NEUROTOXICITY RESEARCH, 2022, vol. 40, no. 5, pp. 1597-1623. ISSN 1029-8428. Dostupné na: https://doi.org/10.1007/s12640-022-00564-w. WU, Qi - KARTHIVASHAN, Govindarajan - NAKHAEI-NEJAD, Maryam - ANAND, Bibin G. - GIULIANI, Fabrizio - KAR, Satyabrata. Native PLGA nanoparticles regulate APP metabolism and protect neurons against ?-amyloid toxicity: Potential significance in Alzheimer's disease pathology. In INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, vol. 219, no., pp. 1180-1196. ISSN 0141-8130. Dostupné na: https://doi.org/10.1016/j.ijbiomac.2022.08.148. NAMCHAIW, Poommaree - BUNREANGSRI, Patapon - EIAMCHAROEN, Piyaporn - EIAMBOONSERT, Salita - POO-ARPORN, Rungtiva P. An in vitro workflow of neuron-laden agarose-laminin hydrogel for studying small molecule-induced amyloidogenic condition. In PLOS ONE, 2022, vol. 17, no. 8, pp. ISSN 1932-6203. Dostupné na: https://doi.org/10.1371/journal.pone.0273458. LIMONE, Adriana - VENERUSO, Iolanda - D'ARGENIO, Valeria - SARNATARO, Daniela. Endosomal trafficking and related genetic underpinnings as a hub in Alzheimer's disease. In JOURNAL OF CELLULAR PHYSIOLOGY, 2022, vol. 237, no. 10, pp. 3803-3815. ISSN 0021-9541. Dostupné na: https://doi.org/10.1002/jcp.30864. AUGUST, Isabel - SEMENDEFERI, Katerina - MARCHETTO, Maria Carolina. Brain aging, Alzheimer's disease, and the role of stem cells in primate comparative studies. In JOURNAL OF COMPARATIVE NEUROLOGY, 2022, vol. 530, no. 17, pp. 2940-2953. ISSN 0021-9967. Dostupné na: https://doi.org/10.1002/cne.25394. ANAND, Bibin - WU, Qi - NAKHAEI-NEJAD, Maryam - KARTHIVASHAN, Govindarajan - DOROSH, Lyudmyla - AMIDIAN, Sara - DAHAL, Abhishek - LI, Xiuju - STEPANOVA, Maria - WILLE, Holger - GIULIANI, Fabrizio - KAR, Satyabrata. Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology. In BIOACTIVE MATERIALS, 2022, vol. 17, no., pp. 506-525. Dostupné na: https://doi.org/10.1016/j.bioactmat.2022.05.030. BEHL, Tapan - KAUR, Ishnoor - SEHGAL, Aayush - SINGH, Sukhbir - SHARMA, Neelam - CHIGURUPATI, Sridevi - FELEMBAN, Shatha Ghazi - ALSUBAYIEL, Amal M. - IQBAL, Muhammad Shahid - BHATIA, Saurabh - AL-HARRASI, Ahmed - BUNGAU, Simona - MOSTAFAVI, Ebrahim. "Cutting the Mustard"with Induced Pluripotent Stem Cells: An Overview and Applications in Healthcare Paradigm. In STEM CELL REVIEWS AND REPORTS, 2022, vol. 18, no. 8, pp. 2757-2780. ISSN 2629-3269. Dostupné na: https://doi.org/10.1007/s12015-022-10390-4. OLESEN, Margrethe A. - VILLAVICENCIO-TEJO, Francisca - QUINTANILLA, Rodrigo A. The use of fibroblasts as a valuable strategy for studying mitochondrial impairment in neurological disorders. In TRANSLATIONAL NEURODEGENERATION, 2022, vol. 11, no. 1, pp. ISSN 2047-9158. Dostupné na: https://doi.org/10.1186/s40035-022-00308-y. KONDO, Takayuki - YADA, Yuichiro - IKEUCHI, Takeshi - INOUE, Haruhisa. CDiP technology for reverse engineering of sporadic Alzheimer's disease. In JOURNAL OF HUMAN GENETICS, 2022, vol., no., pp. ISSN 1434-5161. Dostupné na: https://doi.org/10.1038/s10038-022-01047-8. KUSUMOTO, Dai - YUASA, Shinsuke - FUKUDA, Keiichi. Induced Pluripotent Stem Cell-Based Drug Screening by Use of Artificial Intelligence. In PHARMACEUTICALS, 2022, vol. 15, no. 5, pp. Dostupné na: https://doi.org/10.3390/ph15050562. HASAN, Md Fayad - TRUSHINA, Eugenia. Advances in Recapitulating Alzheimer's Disease Phenotypes Using Human Induced Pluripotent Stem Cell-Based In Vitro Models. In BRAIN SCIENCES, 2022, vol. 12, no. 5, pp. Dostupné na: https://doi.org/10.3390/brainsci12050552. LEE, Ju-Hyun - YOO, Geon - CHOI, Juhyun - PARK, Si-Hyung - SHIN, Hyogeun - PRASAD, Renuka - LEE, Yeunehee - AHN, Mee Ryung - CHO, Il-Joo - SUN, Woong. Cell-line dependency in cerebral organoid induction: cautionary observations in Alzheimer's disease patient-derived induced pluripotent stem cells. In MOLECULAR BRAIN, 2022, vol. 15, no. 1, pp. Dostupné na: https://doi.org/10.1186/s13041-022-00928-5. FANIZZA, Francesca - CAMPANILE, Marzia - FORLONI, Gianluigi - GIORDANO, Carmen - ALBANI, Diego. Induced pluripotent stem cell-based organ-on-a-chip as personalized drug screening tools: A focus on neurodegenerative disorders. In JOURNAL OF TISSUE ENGINEERING, 2022, vol. 13, no., pp. ISSN 2041-7314. Dostupné na: https://doi.org/10.1177/20417314221095339. BREZOVAKOVA, Veronika - SYKOVA, Eva - JADHAV, Santosh. Astrocytes Derived from Familial and Sporadic Alzheimer's Disease iPSCs Show Altered Calcium Signaling and Respond Differently to Misfolded Protein Tau. In CELLS, 2022, vol. 11, no. 9, pp. Dostupné na: https://doi.org/10.3390/cells11091429. CANNAVO, Claudia - CLEVERLEY, Karen - MADURO, Cheryl - MUMFORD, Paige - MOULDING, Dale - FISHER, Elizabeth M. C. - WISEMAN, Frances K. Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome. In PLOS ONE, 2022, vol. 17, no. 5, pp. ISSN 1932-6203. Dostupné na: https://doi.org/10.1371/journal.pone.0262558. TELLO, Judith A. - WILLIAMS, Haley E. - EPPLER, Robert M. - STEINHILB, Michelle L. - KHANNA, May. Animal Models of Neurodegenerative Disease: Recent Advances in Fly Highlight Innovative Approaches to Drug Discovery. In FRONTIERS IN MOLECULAR NEUROSCIENCE, 2022, vol. 15, no., pp. ISSN 1662-5099. Dostupné na: https://doi.org/10.3389/fnmol.2022.883358. KIM, Jennifer Yejean - MO, Hyunkyung - KIM, Juryun - KIM, Jang Woon - NAM, Yoojun - RIM, Yeri Alice - JU, Ji Hyeon. Mitigating Effect of Estrogen in Alzheimer's Disease-Mimicking Cerebral Organoid. In FRONTIERS IN NEUROSCIENCE, 2022, vol. 16, no., pp. Dostupné na: https://doi.org/10.3389/fnins.2022.816174. GABRIELE, Rebecca M. C. - ABEL, Emily - FOX, Nick C. - WRAY, Selina - ARBER, Charles. Knockdown of Amyloid Precursor Protein: Biological Consequences and Clinical Opportunities. In FRONTIERS IN NEUROSCIENCE, 2022, vol. 16, no., pp. Dostupné na: https://doi.org/10.3389/fnins.2022.835645. MOAZAMIYANFAR, Reza - HALABIAN, Raheleh - GHOLLASI, Marzieh - POORMOGHADAM, Delaram - ENTEZARI, Maliheh - ENDORAMI, Seyed Ehsan. Neural Differentiation of Human-Induced Pluripotent Stem Cells (hiPSc) on Surface-Modified Nanofibrous Scaffolds Coated with Platelet-Rich Plasma. In NEUROCHEMICAL RESEARCH, 2022, vol. 47, no. 7, pp. 1991-2001. ISSN 0364-3190. Dostupné na: https://doi.org/10.1007/s11064-022-03584-2. VISSER, Pieter Jelle - REUS, Lianne M. - GOBOM, Johan - JANSEN, Iris - DICKS, Ellen - VAN DER LEE, Sven J. - TSOLAKI, Magda - VERHEY, Frans R. J. - POPP, Julius - MARTINEZ-LAGE, Pablo - VANDENBERGHE, Rik - LLEO, Alberto - MOLINUEVO, Jose Luis - ENGELBORGHS, Sebastiaan - FREUND-LEVI, Yvonne - FROELICH, Lutz - SLEEGERS, Kristel - DOBRICIC, Valerija - LOVESTONE, Simon - STREFFER, Johannes - VOS, Stephanie J. B. - BOS, Isabelle - SMIT, August B. - BLENNOW, Kaj - SCHELTENS, Philip - TEUNISSEN, Charlotte E. - BERTRAM, Lars - ZETTERBERG, Henrik - TIJMS, Betty M. Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. In MOLECULAR NEURODEGENERATION, 2022, vol. 17, no. 1, pp. Dostupné na: https://doi.org/10.1186/s13024-022-00521-3. KUMAR, Mandeep - NHUNG THI PHUONG NGUYEN - MILANESE, Marco - BONANNO, Giambattista. Insights into Human-Induced Pluripotent Stem Cell-Derived Astrocytes in Neurodegenerative Disorders. In BIOMOLECULES, 2022, vol. 12, no. 3, pp. Dostupné na: https://doi.org/10.3390/biom12030344. LIM, Jung Yeon - LEE, Jung Eun - PARK, Soon A. - PARK, Sang In - YON, Jung-Min - PARK, Jeong-Ah - JEUN, Sin-Soo - KIM, Seung Joon - LEE, Hong Jun - KIM, Sung Won - YANG, Seung Ho. Protective Effect of Human-Neural-Crest-Derived Nasal Turbinate Stem Cells against Amyloid-beta Neurotoxicity through Inhibition of Osteopontin in a Human Cerebral Organoid Model of Alzheimer's Disease. In CELLS, 2022, vol. 11, no. 6, pp. Dostupné na: https://doi.org/10.3390/cells11061029. NOGUEIRA, Giovanna O. O. - GARCEZ, Patricia P. P. - BARDY, Cedric - CUNNINGHAM, Mark O. O. - SEBOLLELA, Adriano. Modeling the Human Brain With ex vivo Slices and in vitro Organoids for Translational Neuroscience. In FRONTIERS IN NEUROSCIENCE, 2022, vol. 16, no., pp. Dostupné na: https://doi.org/10.3389/fnins.2022.838594. LANGLIE, Jake - MITTAL, Rahul - FINBERG, Ariel - BENCIE, Nathalie - MITTAL, Jeenu - OMIDIAN, Hossein - OMIDI, Yadollah - ESHRAGHI, Adrien. Unraveling pathological mechanisms in neurological disorders: the impact of cell-based and organoid models. In NEURAL REGENERATION RESEARCH, 2022, vol. 17, no. 10, pp. 2131-2140. ISSN 1673-5374. Dostupné na: https://doi.org/10.4103/1673-5374.335836. MANSFIELD, Corrin - ZHAO, Ming-Tao - BASU, Madhumita. Translational potential of hiPSCs in predictive modeling of heart development and disease. In BIRTH DEFECTS RESEARCH, 2022, vol. 114, no. 16, pp. 926-947. ISSN 2472-1727. Dostupné na: https://doi.org/10.1002/bdr2.1999. BUBNYS, Adele - TSAI, Li-Huei. Harnessing cerebral organoids for Alzheimer's disease research. In CURRENT OPINION IN NEUROBIOLOGY, 2022, vol. 72, no., pp. 120-130. ISSN 0959-4388. Dostupné na: https://doi.org/10.1016/j.conb.2021.10.003. SRINIVASAN, Gayathri - BRAFMAN, David A. The Emergence of Model Systems to Investigate the Link Between Traumatic Brain Injury and Alzheimer's Disease. In FRONTIERS IN AGING NEUROSCIENCE, 2022, vol. 13, no., pp. ISSN 1663-4365. Dostupné na: https://doi.org/10.3389/fnagi.2021.813544. MILKY, Bridget - ZABOLOCKI, Michael - AL-BATAINEH, Sameer A. - VAN DEN HURK, Mark - GREENBERG, Zarina - TURNER, Lucy - MAZZACHI, Paris - WILLIAMS, Amber - ILLEPERUMA, Imanthi - ADAMS, Robert - STRINGER, Brett W. - ORMSBY, Rebecca - POONNOOSE, Santosh - SMITH, Louise E. - KRASOWSKA, Marta - WHITTLE, Jason D. - SIMULA, Antonio - BARDY, Cedric. Long-term adherence of human brain cells in vitro is enhanced by charged amine-based plasma polymer coatings. In STEM CELL REPORTS, 2022, vol. 17, no. 3, pp. 489-506. ISSN 2213-6711. Dostupné na: https://doi.org/10.1016/j.stemcr.2022.01.013. YANG, Shi Yu - TAANMAN, Jan-Willem - GEGG, Matthew - SCHAPIRA, Anthony H. Ambroxol reverses tau and alpha-synuclein accumulation in a cholinergic N370S GBA1 mutation model. In HUMAN MOLECULAR GENETICS, 2022, vol. 31, no. 14, pp. 2396-2405. ISSN 0964-6906. Dostupné na: https://doi.org/10.1093/hmg/ddac038. BINDER, Jessica - URSU, Oleg - BOLOGA, Cristian - JIANG, Shanya - MAPHIS, Nicole - DADRAS, Somayeh - CHISHOLM, Devon - WEICK, Jason - MYERS, Orrin - KUMAR, Praveen - YANG, Jeremy J. - BHASKAR, Kiran - OPREA, Tudor. Machine learning prediction and tau-based screening identifies potential Alzheimer's disease genes relevant to immunity. In COMMUNICATIONS BIOLOGY, 2022, vol. 5, no. 1, pp. Dostupné na: https://doi.org/10.1038/s42003-022-03068-7. OKANO, Hideyuki - MORIMOTO, Satoru. iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders. In CELL STEM CELL, 2022, vol. 29, no. 2, pp. 189-208. ISSN 1934-5909. Dostupné na: https://doi.org/10.1016/j.stem.2022.01.007. BANERJEE, Rajashree - RAI, Arushi - IYER, Shreyas M. - NARWAL, Sonia - TARE, Meghana. Animal models in the study of Alzheimer's disease and Parkinson's disease: A historical perspective. In ANIMAL MODELS AND EXPERIMENTAL MEDICINE, 2022, vol. 5, no. 1, pp. 27-37. ISSN 2096-5451. Dostupné na: https://doi.org/10.1002/ame2.12209. BARAK, Martin - FEDOROVA, Veronika - POSPISILOVA, Veronika - RASKA, Jan - VOCHYANOVA, Simona - SEDMIK, Jiri - HRIBKOVA, Hana - KLIMOVA, Hana - VANOVA, Tereza - BOHACIAKOVA, Dasa. Human iPSC-Derived Neural Models for Studying Alzheimer's Disease: from Neural Stem Cells to Cerebral Organoids. In STEM CELL REVIEWS AND REPORTS, 2022, vol. 18, no. 2, pp. 792-820. ISSN 2629-3269. Dostupné na: https://doi.org/10.1007/s12015-021-10254-3. HOU, Pei-Shan - KUO, Hung-Chih. Central nervous system organoids for modeling neurodegenerative diseases. In IUBMB LIFE, 2022, vol. 74, no. 8, pp. 812-825. ISSN 1521-6543. Dostupné na: https://doi.org/10.1002/iub.2595. ELBERT, Donald L. - PATTERSON, Bruce W. - LUCEY, Brendan P. - BENZINGER, Tammie L. S. - BATEMAN, Randall J. Importance of CSF-based A beta clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways. In COMMUNICATIONS BIOLOGY, 2022, vol. 5, no. 1, pp. Dostupné na: https://doi.org/10.1038/s42003-022-03037-0. CALDWELL, Andrew B. - LIU, Qing - ZHANG, Can - SCHROTH, Gary P. - GALASKO, Douglas R. - RYNEARSON, Kevin D. - TANZI, Rudolph E. - YUAN, Shauna H. - WAGNER, Steven L. - SUBRAMANIAM, Shankar. Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease. In ALZHEIMERS & DEMENTIA, 2022, vol. 18, no. 11, pp. 2117-2130. ISSN 1552-5260. Dostupné na: https://doi.org/10.1002/alz.12553. GREKHNEV, Dmitriy A. - KAZNACHEYEVA, Elena V. - VIGONT, Vladimir A. Patient-Specific iPSCs-Based Models of Neurodegenerative Diseases: Focus on Aberrant Calcium Signaling. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, vol. 23, no. 2, pp. Dostupné na: https://doi.org/10.3390/ijms23020624. CLEMENT, Jean-Pierre - AL-ALWAN, Laila - GLASGOW, Stephen D. - STOLOW, Avya - DING, Yi - MELO, Thaiany Quevedo - KHAYACHI, Anouar - LIU, Yumin - HELLMUND, Markus - HAAG, Rainer - MILNERWOOD, Austen J. - GRUTTER, Peter - KENNEDY, Timothy E. Dendritic Polyglycerol Amine: An Enhanced Substrate to Support Long-Term Neural Cell Culture. In ASN NEURO, 2022, vol. 14, no., pp. ISSN 1759-0914. Dostupné na: https://doi.org/10.1177/17590914211073276. LAMBERT, Erwan - SAHA, Orthis - LANDEIRA, Bruna Soares - DE FARIAS, Ana Raquel Melo - HERMANT, Xavier - CARRIER, Arnaud - PELLETIER, Alexandre - GADAUT, Johanna - DAVOINE, Lindsay - DUPONT, Cloe - AMOUYEL, Philippe - BONNEFOND, Amelie - LAFONT, Frank - ABDELFETTAH, Farida - VERSTREKEN, Patrik - CHAPUIS, Julien - BAROIS, Nicolas - DELAHAYE, Fabien - DERMAUT, Bart - LAMBERT, Jean-Charles - COSTA, Marcos R. - DOURLEN, Pierre. The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects. In ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2022, vol. 10, no. 1, pp. ISSN 2051-5960. Dostupné na: https://doi.org/10.1186/s40478-021-01285-5. BARTESAGHI, Renata - VICARI, Stefano - MOBLEY, William C. Prenatal and Postnatal Pharmacotherapy in Down Syndrome: The Search to Prevent or Ameliorate Neurodevelopmental and Neurodegenerative Disorders. In ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2022, vol. 62, no., pp. 211-233. ISSN 0362-1642. Dostupné na: https://doi.org/10.1146/annurev-pharmtox-041521-103641. CAI, Qian - GANESAN, Dhasarathan. Regulation of neuronal autophagy and the implications in neurodegenerative diseases. In NEUROBIOLOGY OF DISEASE, 2022, vol. 162, no., pp. ISSN 0969-9961. Dostupné na: https://doi.org/10.1016/j.nbd.2021.105582. VU THU THUY NGUYEN - KOENIG, Svenja - EGGERT, Simone - ENDRES, Kristina - KINS, Stefan. The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research. In BIOLOGICAL CHEMISTRY, 2022, vol. 403, no. 1, pp. 3-26. ISSN 1431-6730. Dostupné na: https://doi.org/10.1515/hsz-2021-0214. SAWA, Mariko - OVERK, Cassia - BECKER, Ann - DERSE, Dominique - ALBAY, Ricardo - WELDY, Kim - SALEHI, Ahmad - BEACH, Thomas G. - DORAN, Eric - HEAD, Elizabeth - YU, Y. Eugene - MOBLEY, William C. Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model. In ALZHEIMERS & DEMENTIA, 2022, vol. 18, no. 6, pp. 1203-1234. ISSN 1552-5260. Dostupné na: https://doi.org/10.1002/alz.12463. BLANCHARD, Joel W. - VICTOR, Matheus B. - TSAI, Li-Huei. Dissecting the complexities of Alzheimer disease with in vitro models of the human brain. In NATURE REVIEWS NEUROLOGY, 2022, vol. 18, no. 1, pp. 25-39. ISSN 1759-4758. Dostupné na: https://doi.org/10.1038/s41582-021-00578-6. CHIAVELLINI, Priscila - CANATELLI-MALLAT, Martina - LEHMANN, Marianne - GOYA, Rodolfo - MOREL, Gustavo. Therapeutic potential of glial cell line-derived neurotrophic factor and cell reprogramming for hippocampal-related neurological disorders. In NEURAL REGENERATION RESEARCH, 2022, vol. 17, no. 3, pp. 469-476. ISSN 1673-5374. Dostupné na: https://doi.org/10.4103/1673-5374.320966. ZAYED, M.A. - SULTAN, S. - ALSAAB, H.O. - YOUSOF, S.M. - ALREFAEI, G.I. - ALSUBHI, N.H. - ALKARIM, S. - AL GHAMDI, K.S. - BAGABIR, S.A. - JANA, A. - ALGHAMDI, B.S. - ATTA, H.M. - ASHRAF, G.M. Stem-Cell-Based Therapy: The Celestial Weapon against Neurological Disorders. In CELLS. NOV 2022, vol. 11, no. 21. Dostupné na: https://doi.org/10.3390/cells11213476. CHEN, H. - JIN, X. - LI, T. - YE, Z. Brain organoids: Establishment and application. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. ISSN 2296-634X, NOV 23 2022, vol. 10. Dostupné na: https://doi.org/10.3389/fcell.2022.1029873. HERDY, J.R. - TRAXLER, L. - AGARWAL, R.K. - KARBACHER, L. - SCHLACHETZKI, J.C.M. - BOEHNKE, L. - ZANGWILL, D. - GALASKO, D. - GLASS, C.K. - MERTENS, J. - GAGE, F.H. Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease. In CELL STEM CELL. ISSN 1934-5909, DEC 1 2022, vol. 29, no. 12, p. 1637-+. Dostupné na: https://doi.org/10.1016/j.stem.2022.11.010. MAHALI, S. - MARTINEZ, R. - KING, M. - VERBECK, A. - HARARI, O. - BENITEZ, B.A. - HORIE, K. - SATO, C. - TEMPLE, S. - KARCH, C.M. Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. In TRANSLATIONAL PSYCHIATRY. ISSN 2158-3188, DEC 10 2022, vol. 12, no. 1. Dostupné na: https://doi.org/10.1038/s41398-022-02274-5. AVERSANO, S. - CAIAZZA, C. - CAIAZZO, M. Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures. In FRONTIERS IN AGING NEUROSCIENCE. ISSN 1663-4365, DEC 20 2022, vol. 14. Dostupné na: https://doi.org/10.3389/fnagi.2022.1069482. Kategória ADCA - Vedecké práce v zahraničných karentovaných časopisoch impaktovaných Kategória (od 2022) V3 - Vedecký výstup publikačnej činnosti z časopisu Typ výstupu článok Rok vykazovania 2012 Registrované v WOS Registrované v SCOPUS Registrované v CCC DOI 10.1038/nature10821 
článok
Názov súboru Prístup Veľkosť Stiahnuté Typ Licence Probing sporadic and familial Alzheimer´s disease using induced pluripotent stem cells.pdf Prístupný 896.9 KB 2 Vydavateľská verzia rok CC IF IF Q (best) JCR Av Jour IF Perc SJR SJR Q (best) CiteScore A rok vydania rok metriky IF IF Q (best) SJR SJR Q (best) 2012 2011 36.280 Q1 17.598 Q1
Počet záznamov: 1