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Why is the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine in its diphosphorylated form (PMEApp(4-)) initially a better substrate for polymerases than (2 '-deoxy)adenosine 5 '-triphosphate (dATP(4-)/ATP(4-))? Considerations on the mechanism of nucleic acid polymerases

  1. TitleWhy is the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine in its diphosphorylated form (PMEApp(4-)) initially a better substrate for polymerases than (2 '-deoxy)adenosine 5 '-triphosphate (dATP(4-)/ATP(4-))? Considerations on the mechanism of nucleic acid polymerases
    Author infoHelmut Sigel ... [et al.]
    Author Sigel Helmut (20%)
    Co-authors Song Bin (16%)
    Blindauer Claudia A. (16%)
    Kapinos Larisa E. (16%)
    Gregáň Fridrich 1944- (16%) UMBFP08 - Katedra chémie
    Prónayová Nadja (16%)
    Source document Chemical Communications. No. 8 (1999), pp. 743-744. - Cambridge : The Royal Society of Chemistry, 1999
    Keywords metal ion complexes   aqueous solution   deriváty - derivatives   hydrolysis  
    LanguageEnglish
    CountryGreat Britian
    systematics 54
    Public work category ADC
    No. of Archival Copy26159
    Repercussion category EVANS, Bradley S. - ZHAO, Changming - GAO, Jiangtao et al. Discovery of the antibiotic phosacetamycin via a new mass spectrometry-based method for phosphonic acid detection. In ACS chemical biology. ISSN 1554-8929, 2013, vol. 8, no. 5, pp. 908-913.
    GUO, Y.H. - GE, Q.C. - LIN, H.K. et al. The role of copper(II) ion in regulating H-bonding and coulombic interactions in copper(II)/tripod/polyphosphate systems. In Transition metal chemistry. ISSN 0340-4285, 2003, vol. 28, no. 6, pp. 609-615.
    Catal.org.BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici
    Databasexpca - PUBLIKAČNÁ ČINNOSŤ
    ReferencesPERIODIKÁ-Súborný záznam periodika
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Number of the records: 1  

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